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  1. Article ; Online: Characteristics and Management of Children with COVID-19 in Turkey

    Cura Yayla, Burcu Ceylan / Özsürekçi, Yasemin / Aykaç, Kübra / Derin Oygar, Pembe / Laçinel Gürlevik, Sibel / İlbay, Sare / Kukul, Musa Gürel / Karahan, Sevilay / Cengiz, Ali Bülent / Ceyhan, Mehmet

    Balkan medical journal

    2020  Volume 37, Issue 6, Page(s) 341–347

    Abstract: Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for ... ...

    Abstract Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for understanding the disease course in children.
    Methods: A retrospective review of the medical records of pediatric patients aged under 18 years who were confirmed as coronavirus disease-2019 between March 11, and June 23, 2020, and were admitted to our hospitals was conducted.
    Results: A total of 220 pediatric patients with coronavirus disease-2019 were evaluated, of which 48.2% were boys, with a median age of 10 years, and 9.5% had underlying diseases. Patients were classified according to severity, with the percentages of asymptomatic, mild, moderate, and critical/severe cases determined to be 25.5%, 45%, 26.8%, and 2.7%, respectively. Extracorporeal membrane oxygenation was required in two patients (0.9%) and mechanical ventilation in three (1.4%). Targeted therapies were used in six patients (2.7%), with hydroxychloroquine being the most commonly used agent either alone (one patient) or in combination with favipiravir (five patients). Two patients (0.9%) died, and nine (4.1%) were still hospitalized during the study period.
    Conclusion: Although the disease course of coronavirus disease-2019 seems to be mild in children, critical illness is significant, and the treatment strategy primarily should consist of supportive care according to our preliminary observations.
    MeSH term(s) Adolescent ; Amides/therapeutic use ; Antimalarials/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Extracorporeal Membrane Oxygenation ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Infant ; Infant, Newborn ; Intensive Care Units, Pediatric ; Length of Stay ; Male ; Pandemics ; Patient Acuity ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pyrazines/therapeutic use ; Respiration, Artificial ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; Turkey
    Chemical Substances Amides ; Antimalarials ; Antiviral Agents ; Pyrazines ; Hydroxychloroquine (4QWG6N8QKH) ; favipiravir (EW5GL2X7E0)
    Keywords covid19
    Language English
    Publishing date 2020-08-31
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2612982-6
    ISSN 2146-3131 ; 2146-3131
    ISSN (online) 2146-3131
    ISSN 2146-3131
    DOI 10.4274/balkanmedj.galenos.2020.2020.7.52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Characteristics and Management of Children with COVID-19 in Turkey

    Cura Yayla, Burcu Ceylan / Özsürekçi, Yasemin / Aykaç, Kübra / Derin Oygar, Pembe / Laçinel Gürlevik, Sibel / Ilbay, Sare / Kukul, Musa Gürel / Karahan, Sevilay / Cengiz, Ali Bülent / Ceyhan, Mehmet

    Balkan Med J

    Abstract: Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for ... ...

    Abstract Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for understanding the disease course in children. Methods: A retrospective review of the medical records of pediatric patients aged under 18 years who were confirmed as coronavirus disease-2019 between March 11, and June 23, 2020, and were admitted to our hospitals was conducted. Results: A total of 220 pediatric patients with coronavirus disease-2019 were evaluated, of which 48.2% were boys, with a median age of 10 years, and 9.5% had underlying diseases. Patients were classified according to severity, with the percentages of asymptomatic, mild, moderate, and critical/severe cases determined to be 25.5%, 45%, 26.8%, and 2.7%, respectively. Extracorporeal membrane oxygenation was required in two patients (0.9%) and mechanical ventilation in three (1.4%). Targeted therapies were used in six patients (2.7%), with hydroxychloroquine being the most commonly used agent either alone (one patient) or in combination with favipiravir (five patients). Two patients (0.9%) died, and nine (4.1%) were still hospitalized during the study period. Conclusion: Although the disease course of coronavirus disease-2019 seems to be mild in children, critical illness is significant, and the treatment strategy primarily should consist of supportive care according to our preliminary observations.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #737856
    Database COVID19

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