Article ; Online: Characteristics and Management of Children with COVID-19 in Turkey
2020 Volume 37, Issue 6, Page(s) 341–347
Abstract: Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for ... ...
Abstract | Aims: Limited data about disease management strategies are available for pediatric patients with coronavirus disease-2019, particularly in Turkey. This study aimed to share the data on patients aged under 18 years in our country to be beneficial for understanding the disease course in children. Methods: A retrospective review of the medical records of pediatric patients aged under 18 years who were confirmed as coronavirus disease-2019 between March 11, and June 23, 2020, and were admitted to our hospitals was conducted. Results: A total of 220 pediatric patients with coronavirus disease-2019 were evaluated, of which 48.2% were boys, with a median age of 10 years, and 9.5% had underlying diseases. Patients were classified according to severity, with the percentages of asymptomatic, mild, moderate, and critical/severe cases determined to be 25.5%, 45%, 26.8%, and 2.7%, respectively. Extracorporeal membrane oxygenation was required in two patients (0.9%) and mechanical ventilation in three (1.4%). Targeted therapies were used in six patients (2.7%), with hydroxychloroquine being the most commonly used agent either alone (one patient) or in combination with favipiravir (five patients). Two patients (0.9%) died, and nine (4.1%) were still hospitalized during the study period. Conclusion: Although the disease course of coronavirus disease-2019 seems to be mild in children, critical illness is significant, and the treatment strategy primarily should consist of supportive care according to our preliminary observations. |
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MeSH term(s) | Adolescent ; Amides/therapeutic use ; Antimalarials/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Child ; Child, Preschool ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Extracorporeal Membrane Oxygenation ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Infant ; Infant, Newborn ; Intensive Care Units, Pediatric ; Length of Stay ; Male ; Pandemics ; Patient Acuity ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pyrazines/therapeutic use ; Respiration, Artificial ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome ; Turkey |
Chemical Substances | Amides ; Antimalarials ; Antiviral Agents ; Pyrazines ; Hydroxychloroquine (4QWG6N8QKH) ; favipiravir (EW5GL2X7E0) |
Keywords | covid19 |
Language | English |
Publishing date | 2020-08-31 |
Publishing country | Turkey |
Document type | Journal Article |
ZDB-ID | 2612982-6 |
ISSN | 2146-3131 ; 2146-3131 |
ISSN (online) | 2146-3131 |
ISSN | 2146-3131 |
DOI | 10.4274/balkanmedj.galenos.2020.2020.7.52 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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