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  1. Article: Unusual Cardiac Manifestations of a Pheochromocytoma in a Girl.

    D'Angelo, Lisa / Parent, Anne-Simone / Derwael, Céline / Hustinx, Roland / Seghaye, Marie-Christine

    Pediatric reports

    2023  Volume 15, Issue 1, Page(s) 237–244

    Abstract: We report the case of an 11-year-old girl who complained about severe asthenia, orthostatic dizziness and abdominal pain for 4 weeks. The primary investigation concluded on febrile urinary tract infection treated by antibiotics. Symptom persistence ... ...

    Abstract We report the case of an 11-year-old girl who complained about severe asthenia, orthostatic dizziness and abdominal pain for 4 weeks. The primary investigation concluded on febrile urinary tract infection treated by antibiotics. Symptom persistence prompted cardiological and endocrinological investigations. A fluctuation in blood pressure, long QT interval, dilation of the aortic root and left ventricular hypertrophy were documented. Elevated levels of urinary catecholamines together with the presence of a right-sided adrenal mass shown via abdominal ultrasound and magnetic resonance imaging were highly suggestive of a pheochromocytoma. This was confirmed by through iodine-123-metaiodobenzylguathdine ([
    Language English
    Publishing date 2023-03-17
    Publishing country Switzerland
    Document type Case Reports
    ISSN 2036-749X
    ISSN 2036-749X
    DOI 10.3390/pediatric15010019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Comment j’explore. Innovations technologiques récentes en scintigraphie de perfusion myocardique et maladie coronarienne.

    Lejeune, Thomas / Derwael, Céline / Bernard, Claire / Letesson, Gaetan / Daenen, Frédéric / Hustinx, Roland

    Revue medicale de Liege

    2023  Volume 78, Issue 10, Page(s) 580–585

    Abstract: Cardiovascular diseases represent the first cause of mortality in the world. Various exploration methods exist to prevent and diagnose them. Among them, cardiac scintigraphy holds a predominant place. There are various equipments and procedures for its ... ...

    Title translation Myocardial perfusion imaging and coronary artery disease : recent technological innovations.
    Abstract Cardiovascular diseases represent the first cause of mortality in the world. Various exploration methods exist to prevent and diagnose them. Among them, cardiac scintigraphy holds a predominant place. There are various equipments and procedures for its realization. We compared the practical aspects of using a conventional Anger camera (Symbia, Siemens) according to a two-days examination protocol with a dedicated cardio CzT camera (D-Spect, Spectrum Dynamics) according to a two-days protocol and a 360°SPECT/CT CzT camera (Veriton, Spectrum Dynamics) according to a one-day protocol. The use of CzT detectors allows a reduction of the activity injected to the patient and of the acquisition time in order to make this examination faster and less irradiating for the patient.
    MeSH term(s) Humans ; Coronary Artery Disease/diagnostic imaging ; Myocardial Perfusion Imaging/methods ; Inventions ; Tomography, Emission-Computed, Single-Photon/methods ; Gamma Cameras
    Language French
    Publishing date 2023-10-13
    Publishing country Belgium
    Document type English Abstract ; Practice Guideline
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Deep learning based identification of bone scintigraphies containing metastatic bone disease foci.

    Ibrahim, Abdalla / Vaidyanathan, Akshayaa / Primakov, Sergey / Belmans, Flore / Bottari, Fabio / Refaee, Turkey / Lovinfosse, Pierre / Jadoul, Alexandre / Derwael, Celine / Hertel, Fabian / Woodruff, Henry C / Zacho, Helle D / Walsh, Sean / Vos, Wim / Occhipinti, Mariaelena / Hanin, François-Xavier / Lambin, Philippe / Mottaghy, Felix M / Hustinx, Roland

    Cancer imaging : the official publication of the International Cancer Imaging Society

    2023  Volume 23, Issue 1, Page(s) 12

    Abstract: Purpose: Metastatic bone disease (MBD) is the most common form of metastases, most frequently deriving from prostate cancer. MBD is screened with bone scintigraphy (BS), which have high sensitivity but low specificity for the diagnosis of MBD, often ... ...

    Abstract Purpose: Metastatic bone disease (MBD) is the most common form of metastases, most frequently deriving from prostate cancer. MBD is screened with bone scintigraphy (BS), which have high sensitivity but low specificity for the diagnosis of MBD, often requiring further investigations. Deep learning (DL) - a machine learning technique designed to mimic human neuronal interactions- has shown promise in the field of medical imaging analysis for different purposes, including segmentation and classification of lesions. In this study, we aim to develop a DL algorithm that can classify areas of increased uptake on bone scintigraphy scans.
    Methods: We collected 2365 BS from three European medical centres. The model was trained and validated on 1203 and 164 BS scans respectively. Furthermore we evaluated its performance on an external testing set composed of 998 BS scans. We further aimed to enhance the explainability of our developed algorithm, using activation maps. We compared the performance of our algorithm to that of 6 nuclear medicine physicians.
    Results: The developed DL based algorithm is able to detect MBD on BSs, with high specificity and sensitivity (0.80 and 0.82 respectively on the external test set), in a shorter time compared to the nuclear medicine physicians (2.5 min for AI and 30 min for nuclear medicine physicians to classify 134 BSs). Further prospective validation is required before the algorithm can be used in the clinic.
    MeSH term(s) Male ; Humans ; Deep Learning ; Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/secondary ; Radionuclide Imaging ; Machine Learning ; Algorithms
    Language English
    Publishing date 2023-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2104862-9
    ISSN 1470-7330 ; 1470-7330
    ISSN (online) 1470-7330
    ISSN 1470-7330
    DOI 10.1186/s40644-023-00524-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Distinction of Lymphoma from Sarcoidosis on

    Lovinfosse, Pierre / Ferreira, Marta / Withofs, Nadia / Jadoul, Alexandre / Derwael, Céline / Frix, Anne-Noelle / Guiot, Julien / Bernard, Claire / Diep, Anh Nguyet / Donneau, Anne-Françoise / Lejeune, Marie / Bonnet, Christophe / Vos, Wim / Meyer, Patrick E / Hustinx, Roland

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    2022  Volume 63, Issue 12, Page(s) 1933–1940

    Abstract: Sarcoidosis and lymphoma often share common features ... ...

    Abstract Sarcoidosis and lymphoma often share common features on
    MeSH term(s) Humans ; Fluorodeoxyglucose F18 ; Positron Emission Tomography Computed Tomography ; Retrospective Studies ; Hodgkin Disease/diagnostic imaging ; Machine Learning ; Lymphoma, Large B-Cell, Diffuse ; Sarcoidosis/diagnostic imaging
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2022-05-19
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80272-4
    ISSN 1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
    ISSN (online) 1535-5667
    ISSN 0097-9058 ; 0161-5505 ; 0022-3123
    DOI 10.2967/jnumed.121.263598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Interobserver agreement of [

    Derwael, Céline / Lavergne, Olivier / Lovinfosse, Pierre / Nechifor, Vlad / Salvé, Mallory / Waltregny, David / Hustinx, Roland / Withofs, Nadia

    EJNMMI research

    2020  Volume 10, Issue 1, Page(s) 15

    Abstract: Background: Prostate-specific membrane antigen (PSMA) ligand PET/CT has already provided promising results in prostate cancer (PC) imaging, yet simple and reproductible reporting criteria are still lacking. This study aimed at retrospectively evaluating ...

    Abstract Background: Prostate-specific membrane antigen (PSMA) ligand PET/CT has already provided promising results in prostate cancer (PC) imaging, yet simple and reproductible reporting criteria are still lacking. This study aimed at retrospectively evaluating interobserver agreement of [
    Methods: Forty-three patients with newly diagnosed, histologically proven intermediate- or high-risk PC, eligible for radical prostatectomy and who underwent [
    Conclusion: Visual interpretation of [
    Language English
    Publishing date 2020-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2619892-7
    ISSN 2191-219X
    ISSN 2191-219X
    DOI 10.1186/s13550-020-0596-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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