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  1. Article ; Online: Caution With Conclusions and Context of Mechanical Circulatory Devices-Reply.

    Miller, P Elliott / Desai, Nihar R

    JAMA internal medicine

    2023  Volume 183, Issue 3, Page(s) 277–278

    MeSH term(s) Humans ; Heart Failure/therapy ; Heart Transplantation ; Heart-Assist Devices/adverse effects
    Language English
    Publishing date 2023-01-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2022.6171
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  2. Article ; Online: Moving toward combination lipid-lowering therapy for all patients with atherosclerotic cardiovascular disease.

    Faridi, Kamil F / Desai, Nihar R

    American journal of preventive cardiology

    2023  Volume 14, Page(s) 100491

    Language English
    Publishing date 2023-03-15
    Publishing country Netherlands
    Document type Editorial
    ISSN 2666-6677
    ISSN (online) 2666-6677
    DOI 10.1016/j.ajpc.2023.100491
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  3. Article ; Online: Reimagining Evidence Generation for Heart Failure and the Role of Integrated Health Care Systems.

    Ahmad, Tariq / Desai, Nihar R

    Circulation. Cardiovascular quality and outcomes

    2022  Volume 15, Issue 4, Page(s) e008292

    MeSH term(s) Angiotensin Receptor Antagonists ; Delivery of Health Care, Integrated ; Drug Combinations ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Neprilysin ; Stroke Volume
    Chemical Substances Angiotensin Receptor Antagonists ; Drug Combinations ; Neprilysin (EC 3.4.24.11)
    Language English
    Publishing date 2022-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2483197-9
    ISSN 1941-7705 ; 1941-7713
    ISSN (online) 1941-7705
    ISSN 1941-7713
    DOI 10.1161/CIRCOUTCOMES.121.008292
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  4. Article ; Online: The EHR Has Exposed an Urgent Moral Imperative to Improve Heart Failure Care.

    Ahmad, Tariq / Desai, Nihar R / Clark, Katherine A A

    Journal of the American College of Cardiology

    2023  Volume 81, Issue 14, Page(s) 1317–1319

    MeSH term(s) Humans ; Heart Failure ; Electronic Health Records ; Morals
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.02.040
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  5. Article ; Online: Defining a path toward improved heart failure care.

    Desai, Nihar R / Clark, Katherine A A

    The American journal of managed care

    2023  Volume 29, Issue 10 Suppl, Page(s) S195–S200

    Abstract: Defining a path toward improved heart failure (HF) care is essential, as there is a clear need to improve HF treatment quality, outcomes, and value. This article reviews potential strategies to help improve the quality of HF clinical care and decrease ... ...

    Abstract Defining a path toward improved heart failure (HF) care is essential, as there is a clear need to improve HF treatment quality, outcomes, and value. This article reviews potential strategies to help improve the quality of HF clinical care and decrease costs. To start, HF phenotyping may be useful in guiding patient treatment, as some phenotypes are associated with higher hospitalization costs and longer length of stay. Identifying and addressing social determinants of health that may be barriers to optimal health may improve management of HF and help to prevent disease progression. In addition, patient-reported outcomes can be useful for evaluating the effectiveness of treatment regimens and assessing which treatments lead to a genuine improvement in quality of life (QOL). Recent innovations in payment reform have seen the implementation of value-based payment (VBP) models over the traditional fee-for-service (FFS) models. FFS models can lead to low-quality care focused on treating illness instead of supporting wellness initiatives. By contrast, VBP models aim to decrease excessive health care costs, thereby increasing incentives to hospitals that deliver high-quality patient care. Further, novel care delivery approaches, such as hospital-at-home and other digital tools, can provide patients with lower-cost care and are associated with improved QOL, including reductions in hospital readmission.
    MeSH term(s) Humans ; Quality of Life ; Heart Failure/therapy ; Disease Progression ; Fee-for-Service Plans ; Health Care Costs
    Language English
    Publishing date 2023-09-07
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2035781-3
    ISSN 1936-2692 ; 1088-0224 ; 1096-1860
    ISSN (online) 1936-2692
    ISSN 1088-0224 ; 1096-1860
    DOI 10.37765/ajmc.2023.89418
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    Zs.MG 86: Show issues

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  6. Article ; Online: Nonadherence to lipid-lowering therapy and strategies to improve adherence in patients with atherosclerotic cardiovascular disease.

    Desai, Nihar R / Farbaniec, Michael / Karalis, Dean G

    Clinical cardiology

    2022  Volume 46, Issue 1, Page(s) 13–21

    Abstract: Despite the availability of effective therapies that lower low-density lipoprotein cholesterol (LDL-C) levels in patients with atherosclerotic cardiovascular disease, many eligible patients are inadequately treated and their LDL-C levels remain ... ...

    Abstract Despite the availability of effective therapies that lower low-density lipoprotein cholesterol (LDL-C) levels in patients with atherosclerotic cardiovascular disease, many eligible patients are inadequately treated and their LDL-C levels remain suboptimal. Patient nonadherence to lipid-lowering therapy (LLT) is a major contributor to the failure of LDL-C goal attainment. Several factors have been identified as contributing to LLT nonadherence, including healthcare disparities due to socioeconomic status, age, race, sex, and cost; limited access to healthcare; perceived side effects associated with LLT; health literacy; and the presence of comorbidities. Suboptimal LLT use has also been associated with clinician factors, including failure to identify patients who require LDL-C reassessment, insufficient LDL-C monitoring, and clinical inertia such as a lack of therapy intensification. Several strategies to enhance LLT adherence have been shown to be effective, including the implementation of educational initiatives and tools for both patients and physicians, the use of clinical protocols and algorithms to identify patients at risk and optimize treatment, and improvements in electronic healthcare records. Pharmacy-based programs designed to help patients with prescription refills, including reminders or the use of prescription delivery by mail, have also proven effective. Drugs requiring frequent administration can represent a barrier to treatment adherence; therefore, newer, more effective LLTs with lower frequency of administration and lower potential for polypharmacy may improve patient adherence to LLT. Implementation of strategies to identify patients at risk for LLT nonadherence and the use of flexible tools such as telemedicine to overcome geographical barriers may improve LLT adherence.
    MeSH term(s) Humans ; Cholesterol, LDL ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/prevention & control ; Atherosclerosis/drug therapy ; Comorbidity ; Practice Patterns, Physicians' ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
    Chemical Substances Cholesterol, LDL ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2022-10-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.23935
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    Zs.A 1423: Show issues Location:
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  7. Article ; Online: Increased Dropout Rates in Model Year 4 of the Bundled Payments for Care Improvement Advanced Model.

    Spivack, Steven B / Xin, Xin / Desai, Nihar R

    Journal of general internal medicine

    2022  Volume 37, Issue 11, Page(s) 2901–2903

    MeSH term(s) Humans ; Medicare ; Patient Care Bundles ; Reimbursement Mechanisms ; United States
    Language English
    Publishing date 2022-01-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-021-07290-7
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    Zs.A 2205: Show issues Location:
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  8. Article ; Online: SGLT2 Inhibitors Should Be Considered for All Patients With Heart Failure.

    Ahmad, Tariq / Desai, Nihar R / Velazquez, Eric J

    Journal of the American College of Cardiology

    2022  Volume 80, Issue 14, Page(s) 1311–1313

    MeSH term(s) Diabetes Mellitus, Type 2 ; Glucose ; Heart Failure/drug therapy ; Humans ; Sodium-Glucose Transporter 2 ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use ; Stroke Volume
    Chemical Substances Sodium-Glucose Transporter 2 ; Sodium-Glucose Transporter 2 Inhibitors ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2022-08-27
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.08.005
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  9. Article ; Online: From Reactivity to Proactivity: On the Path to Pre-Empting Heart Failure Hospitalizations.

    Desai, Nihar R / Krumholz, Harlan M

    JACC. Heart failure

    2020  Volume 8, Issue 12, Page(s) 1035–1037

    MeSH term(s) Delivery of Health Care ; Heart Failure/therapy ; Hospitalization ; Humans
    Language English
    Publishing date 2020-11-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2020.09.007
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  10. Article ; Online: US False Claims Act Investigations of Unnecessary Percutaneous Coronary Interventions.

    Howard, David H / Desai, Nihar R

    JAMA internal medicine

    2020  Volume 180, Issue 11, Page(s) 1534–1536

    MeSH term(s) Coronary Artery Disease/surgery ; Fraud/legislation & jurisprudence ; Humans ; Percutaneous Coronary Intervention/legislation & jurisprudence ; United States ; Unnecessary Procedures/statistics & numerical data
    Language English
    Publishing date 2020-09-19
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2020.2812
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