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  1. Article: Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia

    Desai, Nirali S. / Tukvadze, Nestani / Frediani, Jennifer K.

    Nutrition

    2012  Volume 28, Issue 4, Page(s) 362

    Language English
    Document type Article
    ZDB-ID 639259-3
    ISSN 0899-9007
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

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  2. Article ; Online: Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials.

    Yamshchikov, Alexandra V / Desai, Nirali S / Blumberg, Henry M / Ziegler, Thomas R / Tangpricha, Vin

    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

    2009  Volume 15, Issue 5, Page(s) 438–449

    Abstract: Objective: To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in settings of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence ... ...

    Abstract Objective: To review the existing human controlled intervention studies of vitamin D as adjunctive therapy in settings of infection and provide recommendations for design and implementation of future studies in this field on the basis of the evidence reviewed.
    Methods: We conducted a systematic review of randomized controlled clinical trials that studied vitamin D for treatment or prevention of infectious diseases in humans. Studies from 1948 through 2009 were identified through search terms in PubMed and Ovid MEDLINE.
    Results: Thirteen published controlled trials were identified by our search criteria. Ten trials were placebo controlled, and 9 of the 10 were conducted in a rigorous double-blind design. The selected clinical trials demonstrated substantial heterogeneity in baseline patient demographics, sample size, and vitamin D intervention strategies. Serious adverse events attributable to vitamin D supplementation were rare across all studies. On the basis of studies reviewed to date, the strongest evidence supports further research into adjunctive vitamin D therapy for tuberculosis, influenza, and viral upper respiratory tract illnesses. In the selected studies, certain aspects of study design are highlighted to help guide future clinical research in the field.
    Conclusion: More rigorously designed clinical trials are needed for further evaluation of the relationship between vitamin D status and the immune response to infection as well as for delineation of necessary changes in clinical practice and medical care of patients with vitamin D deficiency in infectious disease settings.
    MeSH term(s) Communicable Diseases/drug therapy ; Communicable Diseases/microbiology ; Communicable Diseases/transmission ; Communicable Diseases/virology ; Humans ; Randomized Controlled Trials as Topic ; Vitamin D/therapeutic use ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/prevention & control
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2009-06-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review ; Systematic Review
    ZDB-ID 1473503-9
    ISSN 1934-2403 ; 1530-891X
    ISSN (online) 1934-2403
    ISSN 1530-891X
    DOI 10.4158/EP09101.ORR
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5034: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 508: Show issues

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  3. Article ; Online: Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia.

    Desai, Nirali S / Tukvadze, Nestani / Frediani, Jennifer K / Kipiani, Maia / Sanikidze, Ekaterine / Nichols, Memorie M / Hebbar, Gautam / Kempker, Russell R / Mirtskhulava, Veriko / Kalandadze, Iagor / Seydafkan, Shabnam / Sutaria, Nilay / Chen, Tai C / Blumberg, Henry M / Ziegler, Thomas R / Tangpricha, Vin

    Nutrition (Burbank, Los Angeles County, Calif.)

    2012  Volume 28, Issue 4, Page(s) 362–366

    Abstract: Objective: Vitamin D deficiency is common in tuberculosis (TB) and this may modulate immune responses. This study investigated vitamin D status in patients with TB and examined the sources of vitamin D in Tbilisi, Georgia.: Methods: We measured ... ...

    Abstract Objective: Vitamin D deficiency is common in tuberculosis (TB) and this may modulate immune responses. This study investigated vitamin D status in patients with TB and examined the sources of vitamin D in Tbilisi, Georgia.
    Methods: We measured plasma 25-hydroxyvitamin D (25[OH]D) and dietary vitamin D intake in patients with pulmonary TB (n = 85) in Tbilisi, Georgia. To determine the impact of season on vitamin D status, we tested the in vitro conversion of 7-dehydrocholesterol (7-DHC) to previtamin D(3) after sunlight exposure.
    Results: In subjects with TB, mean plasma 25(OH)D concentrations were 14.4 ± 7.0 ng/mL, and vitamin D insufficiency (25[OH]D <30 ng/mL) occurred in 97% of subjects. The dietary sources of vitamin D were mainly fish, eggs, and butter. The daily intake was well below recommended daily intakes in subjects with TB (172 ± 196 IU). The conversion of 7-DHC to previtamin D(3) was undetectable from October to March and highest in June and July from 11:00 to 14:00 h.
    Conclusion: An insufficient vitamin D dietary intake and a limited production of vitamin D from sunlight for most of the year may explain the high prevalence of vitamin D insufficiency in patients with TB in Tbilisi.
    MeSH term(s) Adult ; Cholecalciferol/blood ; Dehydrocholesterols/blood ; Diet ; Female ; Georgia/epidemiology ; Humans ; Male ; Middle Aged ; Nutrition Policy ; Nutritional Requirements ; Nutritional Status ; Prevalence ; Sunlight ; Tuberculosis, Pulmonary/blood ; Tuberculosis, Pulmonary/complications ; Vitamin D/administration & dosage ; Vitamin D/analogs & derivatives ; Vitamin D/blood ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/epidemiology ; Vitamins/administration & dosage ; Vitamins/blood ; Young Adult
    Chemical Substances Dehydrocholesterols ; Vitamins ; Vitamin D (1406-16-2) ; Cholecalciferol (1C6V77QF41) ; 25-hydroxyvitamin D (A288AR3C9H) ; 7-dehydrocholesterol (BK1IU07GKF)
    Language English
    Publishing date 2012-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2011.08.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2290: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia

    Desai, Nirali S / Tukvadze, Nestani / Frediani, Jennifer K / Kipiani, Maia / Sanikidze, Ekaterine / Nichols, Memorie M / Hebbar, Gautam / Kempker, Russell R / Mirtskhulava, Veriko / Kalandadze, Iagor / Seydafkan, Shabnam / Sutaria, Nilay / Chen, Tai C / Blumberg, Henry M / Ziegler, Thomas R / Tangpricha, Vin

    Nutrition. 2012 Apr., v. 28, no. 4

    2012  

    Abstract: OBJECTIVE: Vitamin D deficiency is common in tuberculosis (TB) and this may modulate immune responses. This study investigated vitamin D status in patients with TB and examined the sources of vitamin D in Tbilisi, Georgia. METHODS: We measured plasma 25- ... ...

    Abstract OBJECTIVE: Vitamin D deficiency is common in tuberculosis (TB) and this may modulate immune responses. This study investigated vitamin D status in patients with TB and examined the sources of vitamin D in Tbilisi, Georgia. METHODS: We measured plasma 25-hydroxyvitamin D (25[OH]D) and dietary vitamin D intake in patients with pulmonary TB (n = 85) in Tbilisi, Georgia. To determine the impact of season on vitamin D status, we tested the in vitro conversion of 7-dehydrocholesterol (7-DHC) to previtamin D3 after sunlight exposure. RESULTS: In subjects with TB, mean plasma 25(OH)D concentrations were 14.4 ± 7.0 ng/mL, and vitamin D insufficiency (25[OH]D <30 ng/mL) occurred in 97% of subjects. The dietary sources of vitamin D were mainly fish, eggs, and butter. The daily intake was well below recommended daily intakes in subjects with TB (172 ± 196 IU). The conversion of 7-DHC to previtamin D3 was undetectable from October to March and highest in June and July from 11:00 to 14:00 h. CONCLUSION: An insufficient vitamin D dietary intake and a limited production of vitamin D from sunlight for most of the year may explain the high prevalence of vitamin D insufficiency in patients with TB in Tbilisi.
    Keywords 7-dehydrocholesterol ; butter ; diet ; eggs ; immune response ; patients ; solar radiation ; tuberculosis ; vitamin D ; vitamin deficiencies ; Georgia
    Language English
    Dates of publication 2012-04
    Size p. 362-366.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 639259-3
    ISSN 1873-1244 ; 0899-9007
    ISSN (online) 1873-1244
    ISSN 0899-9007
    DOI 10.1016/j.nut.2011.08.012
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4802: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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