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Article ; Online: Cutaneous tests and interest of iobitridol in non-immediate hypersensitivity to contrast media: a case series of 43 patients.

Gaudin, O / Deschamps, O / Duong, T A / Gener, G / Paul, M / Luciani, A / Chosidow, O / Wolkenstein, P / Ingen-Housz-Oro, S / Assier, H

Journal of the European Academy of Dermatology and Venereology : JEADV

2020 Volume 34, Issue 4, Page(s) e178–e180

MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Contrast Media/adverse effects ; Drug Hypersensitivity/diagnosis ; Female ; Humans ; Iohexol/adverse effects ; Iohexol/analogs & derivatives ; Male ; Middle Aged ; Retrospective Studies ; Skin Tests
Chemical Substances	Contrast Media ; iobitridol (182ECH14UH) ; Iohexol (4419T9MX03)
Language	English
Publishing date	2020-01-06
Publishing country	England
Document type	Letter
ZDB-ID	1128828-0
ISSN	1468-3083 ; 0926-9959
ISSN (online)	1468-3083
ISSN	0926-9959
DOI	10.1111/jdv.16139
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Article ; Online: Complications After Anterior Cruciate Ligament Reconstruction and Their Relation to the Type of Graft: A Prospective Study of 958 Cases.

Rousseau, Romain / Labruyere, Charlotte / Kajetanek, Charles / Deschamps, Olivia / Makridis, Konstantinos G / Djian, Patrick

The American journal of sports medicine

2019 Volume 47, Issue 11, Page(s) 2543–2549

Abstract: Background: Complications and adverse events after anterior cruciate ligament (ACL) reconstruction are well known, but they have been underestimated in previous studies.: Purpose: To describe the complications and adverse events after ACL ... ...

Abstract	Background: Complications and adverse events after anterior cruciate ligament (ACL) reconstruction are well known, but they have been underestimated in previous studies. Purpose: To describe the complications and adverse events after ACL reconstruction within a 2-year follow-up and analyze them in relation to the type of graft. Study design: Cohort study; Level of evidence, 3. Methods: From 2000 to 2012, 958 patients with an isolated ACL injury underwent surgery by a single knee surgeon. ACL reconstruction was performed with the medial portal technique for the femoral tunnel and the use of bone-patellar tendon-bone (BPTB) or hamstring tendon graft. Patients were reviewed at 6 weeks and 3, 6, 12, and 24 months after surgery with the International Knee Documentation Committee score, plain radiographs, and the KT-1000 arthrometer. Results: Of 958 patients enrolled, 147 (15%) were lost at last follow-up. The 2 groups (bone-patellar tendon-bone [n = 257] and hamstring [n = 554]) were similar regarding the mean age at the time of surgery and preoperative anterior laxity. The main complications were as follows: anterior knee pain (n = 130 of 811, 16%), stiffness (n = 72, 8.8%), secondary meniscal lesions (n = 59, 7.2%), pain attributed to fixation (n = 79, 9.7%), ACL rerupture (n = 47, 5.7%), contralateral ACL ruptures (n = 24, 3%), patellar fractures (n = 3, 0.3%), infections (n = 9, 1%), and thromboembolic complications (n = 5, 0.6%). There was no significant difference between the grafts with respect to the frequency of joint stiffness, secondary meniscal lesions, or anterior knee pain. During the first 2 postoperative years, the percentage of patients with anterior knee pain was higher in the patellar tendon group (23.3% vs 12.6%, Conclusion: The total rate of complications after an ACL reconstruction was 39%, and the surgical revision rate for any reason was 28%. Problems with the hardware material were more frequent in the hamstring group, leading to an increased rate of surgical revision. Anterior knee pain was initially higher in the patellar tendon group, but there was no significant difference in a 2-year interval. The rerupture rate was statistically higher in the hamstring group.
MeSH term(s)	Adolescent ; Adult ; Anterior Cruciate Ligament Reconstruction/classification ; Anterior Cruciate Ligament Reconstruction/methods ; Anterior Cruciate Ligament Reconstruction/statistics & numerical data ; Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Prospective Studies ; Reoperation/statistics & numerical data ; Young Adult
Language	English
Publishing date	2019-08-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	197482-8
ISSN	1552-3365 ; 0363-5465
ISSN (online)	1552-3365
ISSN	0363-5465
DOI	10.1177/0363546519867913
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Article ; Online: Acute exanthemas: a prospective study of 98 adult patients with an emphasis on cytokinic and metagenomic investigation.

Deschamps, O / Ortonne, N / Hüe, S / Rodriguez, C / Deschodt, C / Hirsch, G / Colin, A / Grégoire, L / Delfau-Larue, M-H / Chosidow, O / Wolkenstein, P / Ingen-Housz-Oro, S

The British journal of dermatology

2019 Volume 182, Issue 2, Page(s) 355–363

Abstract: Background: Acute exanthemas (AEs) are frequently seen; they can be caused by drugs or viruses but often the cause is unknown.: Objectives: To describe the clinical, virological and histological aspects of AEs and explore their cytokinic and ... ...

Abstract	Background: Acute exanthemas (AEs) are frequently seen; they can be caused by drugs or viruses but often the cause is unknown. Objectives: To describe the clinical, virological and histological aspects of AEs and explore their cytokinic and metagenomic profiles. Methods: This prospective study examined 98 patients with AE, from February to July 2014. Clinical data were recorded in a standardized chart. Virological investigation and skin biopsies were performed. In addition, blood and skin samples were analysed for cytokines and then by a shotgun metagenomic approach. We identified five groups of patients: those with maculopapular exanthemas (MPEs) that were virally induced (group 1); those with drug-induced MPEs (group 2), those with MPEs that were both viral and drug induced (group 3), those with idiopathic MPEs (group 4) and those with pityriasis rosea (group 5). Results: A virus was identified in 29 cases (human herpesvirus 6, 72%). Cytokinic analysis of the skin (n = 23 MPEs) showed higher levels of interferon-γ and interleukin-1 receptor-α in viral MPEs, higher interleukin-33 levels in idiopathic MPEs, and higher macrophage inflammatory protein 1α levels in drug-induced MPEs. By metagenomics analysis (n = 10 MPEs), viruses identified with routine practice methods were not found in group 1 (n = 4 MPEs). However, Enterovirus A was detected in two cases, especially in a group 1 patient for whom metagenomic analysis rectified the diagnosis of the culprit agent. Conclusions: Human herpesvirus 6 was the virus most frequently identified, and histology did not discriminate MPEs. In addition, the level of interleukin-33 seen in idiopathic MPEs suggests that an environmental factor may be the trigger for these. The results bring into question the utility of routine polymerase chain reaction analysis and viral serology for determining cause in AE. What's already known about this topic? Acute exanthemas, especially maculopapular exanthemas, are a frequent reason for patients consulting emergency and dermatology departments. It is difficult to evaluate the aetiology of acute exanthema based on the clinical aspects. Few data are available on the investigations needed in routine practice, and no prospective series have been published. What does this study add? Our study provides a global and prospective description of acute exanthemas. Cytokine analysis could help to investigate the pathophysiology of idiopathic eruptions. Metagenomic analysis provides new insights about the value of routine practice virological investigations. We show for the first time the feasibility of metagenomics analysis in the skin, which results question the interest of routine PCR and viral sérologies for the exploration of such acute exanthemas.
MeSH term(s)	Adult ; Exanthema/chemically induced ; Exanthema/genetics ; Humans ; Metagenomics ; Pityriasis Rosea ; Prospective Studies ; Skin
Language	English
Publishing date	2019-08-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80076-4
ISSN	1365-2133 ; 0007-0963
ISSN (online)	1365-2133
ISSN	0007-0963
DOI	10.1111/bjd.18166
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Book ; Online: Prospects for $B^0_{(s)}\to\pi^0\pi^0$ and $B^0_{(s)}\to\eta\eta$ modes and corresponding $CP$ asymmetries at Tera-$Z$

Wang, Yuexin / Descotes-Genon, Sébastien / Deschamps, Olivier / Li, Lingfeng / Chen, Shanzhen / Zhu, Yongfeng / Ruan, Manqi

2022

Abstract: The physics potential of measuring $B^0_{(s)}\to\pi^0\pi^0$ and $B^0_{(s)}\to\eta\eta$ decays via four-photon final states at Tera-$Z$ phase of CEPC or FCC-ee is investigated in this paper. We propose an electromagnetic calorimeter (ECAL) with both high ... ...

Abstract	The physics potential of measuring $B^0_{(s)}\to\pi^0\pi^0$ and $B^0_{(s)}\to\eta\eta$ decays via four-photon final states at Tera-$Z$ phase of CEPC or FCC-ee is investigated in this paper. We propose an electromagnetic calorimeter (ECAL) with both high energy resolution and excellent separation power to efficiently reconstruct $\pi^0$ and $\eta$ from hadronic final states with high photon multiplicity. The resulting $B$-meson mass resolution is approximately 30 MeV, allowing 3 $\sigma$ separation between $B^0$ and $B_s^0$. With the assistance of the $b$-jet tagging, the relative sensitivities to $B^0\to\pi^0\pi^0$, $B^0_s\to\pi^0\pi^0$, $B^0\to\eta\eta$, and $B^0_s\to\eta\eta$ signal strengths at Tera-$Z$ are projected as 0.45%, 4.5%, 18%, and 0.95%, respectively. Their dependence on various detector performances is also discussed. In addition, $B^0\to\pi^0\pi^0$ and its two isospin-related modes are paid special attention due to their roles in the determination of the CKM angle $\alpha$ ($\phi_2$). The anticipated precisions of their branching-ratio and $CP$-asymmetry measurements at Tera-$Z$ are evaluated. We show that the measurement of the time-integrated $B^0\to\pi^0\pi^0$ $CP$ asymmetry at Tera-$Z$ is complementary to $B$-factory ones. The precision on $\alpha$ combining $Z$- and $B$-factory results reaches $0.4^\circ$, lower than the systematic uncertainties attached to isospin breaking.
Keywords	High Energy Physics - Phenomenology
Subject code	551
Publishing date	2022-08-17
Publishing country	us
Document type	Book ; Online
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Article ; Online: Treatment of mycosis fungoides and Sézary syndrome with romidepsin: a series of 32 cases from the French Study Group for Cutaneous Lymphoma.

Deschamps, O / Ram-Wolff, C / Beylot-Barry, M / Grange, F / Skowron, F / Dereure, O / Boulinguez, S / Aubin, F / Ingen-Housz-Oro, S / Bagot, M

The British journal of dermatology

2018 Volume 180, Issue 2, Page(s) 423–424

MeSH term(s)	Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/adverse effects ; Depsipeptides/administration & dosage ; Depsipeptides/adverse effects ; Disease Progression ; Follow-Up Studies ; France/epidemiology ; Humans ; Infusions, Intravenous ; Mycosis Fungoides/diagnosis ; Mycosis Fungoides/drug therapy ; Progression-Free Survival ; Severity of Illness Index ; Sezary Syndrome/diagnosis ; Sezary Syndrome/drug therapy ; Sezary Syndrome/mortality ; Skin/drug effects ; Skin/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/drug therapy ; Skin Neoplasms/mortality ; Time Factors
Chemical Substances	Antibiotics, Antineoplastic ; Depsipeptides ; romidepsin (CX3T89XQBK)
Language	English
Publishing date	2018-11-22
Publishing country	England
Document type	Letter
ZDB-ID	80076-4
ISSN	1365-2133 ; 0007-0963
ISSN (online)	1365-2133
ISSN	0007-0963
DOI	10.1111/bjd.17269
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Article ; Online: Splénomégalie palustre hyper-réactive.

Maazoun, F / Deschamps, O / Barros-Kogel, E / Ngwem, E / Fauchet, N / Buffet, P / Froissart, A

La Revue de medecine interne

2015 Volume 36, Issue 11, Page(s) 753–759

Abstract: Hyper-reactive malarial splenomegaly is a rare and severe form of chronic malaria. This condition is a common cause of splenomegaly in endemic areas. The pathophysiology of hyper-reactive malarial splenomegaly involves an intense immune reaction ( ... ...

Title translation	Hyper-reactive malarial splenomegaly.
Abstract	Hyper-reactive malarial splenomegaly is a rare and severe form of chronic malaria. This condition is a common cause of splenomegaly in endemic areas. The pathophysiology of hyper-reactive malarial splenomegaly involves an intense immune reaction (predominantly B cell-driven) to repeated/chronic infections with Plasmodium sp. The diagnosis may be difficult, due to a poorly specific clinical presentation (splenomegaly, fatigue, cytopenias), a long delay between residence in a malaria-endemic area and onset of symptoms, and a frequent absence of parasites on conventional thin and thick blood smears. A strongly contributive laboratory parameter is the presence of high levels of total immunoglobulin M. When the diagnostic of hyper-reactive malarial splenomegaly is considered, search for anti-Plasmodium antibodies and Plasmodium nucleic acids (genus and species) by PCR is useful. Diagnosis of hyper-reactive malarial splenomegaly relies on the simultaneous presence of epidemiological, clinical, biological and follow-up findings. Regression of both splenomegaly and hypersplenism following antimalarial therapy allows the differential diagnosis with splenic lymphoma, a common complication of hyper-reactive malarial splenomegaly. Although rare in Western countries, hyper-reactive malarial splenomegaly deserves increased medical awareness to reduce the incidence of incorrect diagnosis, to prevent progression to splenic lymphoma and to avoid splenectomy.
MeSH term(s)	Antibodies/blood ; Antimalarials/therapeutic use ; Diagnosis, Differential ; Humans ; Immunoglobulin M/blood ; Malaria, Falciparum/diagnosis ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/epidemiology ; Plasmodium falciparum/genetics ; Plasmodium falciparum/immunology ; Splenomegaly/drug therapy ; Splenomegaly/epidemiology ; Splenomegaly/immunology
Chemical Substances	Antibodies ; Antimalarials ; Immunoglobulin M
Language	French
Publishing date	2015-11
Publishing country	France
Document type	English Abstract ; Journal Article ; Review
ZDB-ID	604679-4
ISSN	1768-3122 ; 0248-8663
ISSN (online)	1768-3122
ISSN	0248-8663
DOI	10.1016/j.revmed.2015.06.002
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Book ; Thesis: Recherche du boson de higgs du modele standard minimal dans les etats finals hadroniques avec le detecteur ALEPH A LEP2

Deschamps, Olivier

(EDSF ; 233 ; PCCF T ; 9903)

1999

Author's details	per Olivier Deschamps
Series title	EDSF ; 233 PCCF T ; 9903
Language	French
Size	273 S, graph. Darst
Publisher	Univ. Blaise Pascal
Publishing place	Aubière
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Univ. Blaise Pascal, Diss.--Zugl.: Clermont-Ferrand, 1999
Note	Numéro d'ordre: DU 1129
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Association polyarthrite rhumatoïde--maladie de Kaposi. A propos d'un cas survenant au décours d'une corticothérapie intra-articulaire.

Azais, I / Lambert de Cursay, G / Deblais, F / Deschamps, O / Gandon, P / Alcalay, M / Bontoux, D

Revue du rhumatisme (Ed. francaise : 1993)

1993 Volume 60, Issue 3, Page(s) 240–244

Abstract: A 66 year old Corsican HLA A2 and DR5-positive male with moderately active seropositive destructive rheumatoid arthritis developed Kaposi's sarcoma after intraarticular administration of corticosteroids. He had no history of oral corticosteroid therapy, ... ...

Title translation	Association of rheumatoid arthritis and Kaposi disease. Apropos of a case arising after intraarticular corticotherapy.
Abstract	A 66 year old Corsican HLA A2 and DR5-positive male with moderately active seropositive destructive rheumatoid arthritis developed Kaposi's sarcoma after intraarticular administration of corticosteroids. He had no history of oral corticosteroid therapy, organ transplantation, AIDS, or cancer. Chlorambucil proved ineffective but the outcome was spontaneously favorable following discontinuation of oral corticosteroid therapy initiated after the development of the skin lesions. Six previous reports of concomitant rheumatoid arthritis and Kaposi's sarcoma were found. All six cases occurred following systemic corticosteroid therapy. The high incidence of rheumatoid arthritis and the small number of patients with rheumatoid arthritis and Kaposi's sarcoma suggest that concomitant occurrence of the two conditions may be fortuitous. However, the responsibility of corticosteroid therapy, which preceded development of Kaposi's sarcoma in every case, cannot be ruled out.
MeSH term(s)	Aged ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/immunology ; Chlorambucil/therapeutic use ; Humans ; Immunity ; Injections, Intra-Articular/adverse effects ; Male ; Prednisolone/administration & dosage ; Prednisolone/adverse effects ; Sarcoma, Kaposi/chemically induced ; Xeroderma Pigmentosum/drug therapy ; Xeroderma Pigmentosum/etiology ; Xeroderma Pigmentosum/immunology
Chemical Substances	Chlorambucil (18D0SL7309) ; Prednisolone (9PHQ9Y1OLM)
Language	French
Publishing date	1993-03
Publishing country	France
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	2036640-1
ISSN	1768-3130 ; 1169-8330
ISSN (online)	1768-3130
ISSN	1169-8330
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Article: A propos d'un cas d'asthme á l'anhydride maléique.

Guérin, J C / Deschamps, O / Guillot, Y L / Chavaillon, J M / Kalb, J C

Le Poumon et le coeur

1980 Volume 36, Issue 6, Page(s) 393–395

Abstract: On the basis of a case of asthma due to maleic anhydride, a description is given of occupational asthma due to anhydrides, the physiopathology of which is similar to that related to isocyanates. In contrast to the latter, this disorder is not listed ... ...

Title translation	A case of asthma due to maleic anhydride (author's transl).
Abstract	On the basis of a case of asthma due to maleic anhydride, a description is given of occupational asthma due to anhydrides, the physiopathology of which is similar to that related to isocyanates. In contrast to the latter, this disorder is not listed amongst occupational diseases, which should not prevent action by the occupational health physician.
MeSH term(s)	Adult ; Asthma/chemically induced ; Asthma/diagnosis ; Female ; Furans/adverse effects ; Humans ; Maleic Anhydrides/adverse effects ; Occupational Diseases/chemically induced
Chemical Substances	Furans ; Maleic Anhydrides
Language	French
Publishing date	1980
Publishing country	France
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	208996-8
ISSN	0032-5821
ISSN	0032-5821
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Article: Comparaison de différentes techniques d'exploration fonctionnelle dans le diagnostic précoce du trouble ventilatoire obstructif.

Guillot, Y L / Guérin, J C / Deschamps, O / Chavaillon, J M / Mornex, J F / Kalb, J C

Le Poumon et le coeur

1982 Volume 38, Issue 1, Page(s) 17–23

Abstract: The diagnostic value of different respiratory function tests in the respiratory distress syndrome was compared in 5 groups of subjects: healthy non-smokers, asymptomatic smokers, patients with bronchitis affecting the large bronchi, asthmatic patients ... ...

Title translation	Comparative value of different respiratory function tests for the early diagnosis of the respiratory distress syndrome (author's transl).
Abstract	The diagnostic value of different respiratory function tests in the respiratory distress syndrome was compared in 5 groups of subjects: healthy non-smokers, asymptomatic smokers, patients with bronchitis affecting the large bronchi, asthmatic patients between attacks, and patients with emphysema. Indices measured were the forced expiratory volume per second (FEV1), mean expiratory flow between 25 and 75% of vital capacity (MEF 25-75%), maximum instantaneous flow at 25-50-75% of vital capacity, and peak flow (Vmax 25-50-75%, PF), residual volume, expiratory resistance volume, and the curve of the alveolar plateau of expired nitrogen. The Vmax 50% and the MEF 25-75% appear to be sufficiently sensitive indices of bronchial obstruction in current practice, the MEF 25-75% being simple to measure, and presenting the advantage of not requiring complicated equipment. The Vmax 25% and the respiratory resistance volume present wide inter-individual variations, and this, together with their lack of reproducibility, limit their value in exploratory tests in isolated cases.
MeSH term(s)	Adult ; Aged ; Asthma/diagnosis ; Bronchitis/diagnosis ; Female ; Humans ; Lung Diseases, Obstructive/diagnosis ; Lung Volume Measurements ; Male ; Middle Aged ; Pulmonary Emphysema/diagnosis ; Smoking
Language	French
Publishing date	1982
Publishing country	France
Document type	Comparative Study ; English Abstract ; Journal Article
ZDB-ID	208996-8
ISSN	0032-5821
ISSN	0032-5821
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