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Article ; Online: Can we accurately measure the ankle-brachial index in patients with atrial fibrillation?

Aboyans, Victor / Desormais, Ileana

Hypertension research : official journal of the Japanese Society of Hypertension

2018 Volume 41, Issue 7, Page(s) 487–488

MeSH term(s)	Ankle Brachial Index ; Atrial Fibrillation ; Humans ; Ultrasonography, Doppler
Language	English
Publishing date	2018-05-02
Publishing country	England
Document type	Editorial ; Comment
ZDB-ID	1175297-x
ISSN	1348-4214 ; 0916-9636
ISSN (online)	1348-4214
ISSN	0916-9636
DOI	10.1038/s41440-018-0039-z
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Article ; Online: Hypertension and associated factors in HIV-infected patients receiving antiretroviral treatment in Burundi: a cross-sectional study.

Harimenshi, Déo / Niyongabo, Théodore / Preux, Pierre-Marie / Aboyans, Victor / Desormais, Ileana

Scientific reports

2022 Volume 12, Issue 1, Page(s) 20509

Abstract: Currently, the life expectancy of people living with the human immunodeficiency virus (HIV) and the general population are similar. Hypertension is a major public health issue in Africa and is largely underdiagnosed. Most HIV-infected individuals, ... ...

Abstract	Currently, the life expectancy of people living with the human immunodeficiency virus (HIV) and the general population are similar. Hypertension is a major public health issue in Africa and is largely underdiagnosed. Most HIV-infected individuals, especially those on Anti-Retroviral Therapy (ART) have hypertension. Our project aims to determine the prevalence of hypertension and associated factors amongst HIV-infected adults treated by ART in Burundi. A cross-sectional study was conducted among HIV-infected subjects over the age of 20, managed in five healthcare centers for people living with HIV (PLWH). The World Health Organization STEPWISE survey and anthropometric measurements were employed. Blood pressure was measured according to the ESC 2018 recommendations. 1 250 HIV-infected patients aged between 35.4 and 50.2 years were included (18.4% men). The prevalence of hypertension was 17.4% (95% CI 13.2-22.1). Approximately 47.25% of HIV patients with hypertension were previously undiagnosed. Other factors were associated with HTN, such as being overweight (OR 2.88; 95% CI 1.46-5.62), obesity (OR 2.65; 95% CI 1.27-5.55), longer duration of HIV infection: ≥ 10 years (OR 1.04; 95% CI 1.14-3.20), diabetes (OR 2.1; 95% CI 1.37-3.32) and age (OR 1.13; 95% CI 1.09-1.14). Despite their young age, almost 20% of HIV-ART treated patients had hypertension, 50% of these were undiagnosed. Blood pressure monitoring is crucial in these patients, especially those identified as high-risk, with prompt life and disability-saving interventions.
MeSH term(s)	Adult ; Male ; Humans ; Middle Aged ; Female ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; Cross-Sectional Studies ; Burundi/epidemiology ; Anti-Retroviral Agents/therapeutic use ; Hypertension/complications ; Hypertension/epidemiology
Chemical Substances	Anti-Retroviral Agents
Language	English
Publishing date	2022-11-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-24997-7
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Article ; Online: HIV clinical stages and lower extremity arterial disease among HIV infected outpatients in Burundi.

Desormais, Ileana / Harimenshi, Deo / Niyongabo, Théodore / Lacroix, Philippe / Aboyans, Victor / Preux, Pierre Marie

Scientific reports

2021 Volume 11, Issue 1, Page(s) 8296

Abstract: Chronic disease of people living with human immunodeficiency virus (HIV) infection are now approaching those of the general population. Previous, in vitro studies shown that HIV causes arterial injuries resulting in inflammation and atherosclerosis but ... ...

Abstract	Chronic disease of people living with human immunodeficiency virus (HIV) infection are now approaching those of the general population. Previous, in vitro studies shown that HIV causes arterial injuries resulting in inflammation and atherosclerosis but direct relationship between HIV infection clinical stages and lower extremity arterial disease (LEAD) remain controversial. No study assessed, with an accurate method, both the prevalence of LEAD and the influence of HIV severity on LEAD in HIV outpatients in Central Africa. A cross-sectional study was conducted among 300 HIV-infected outpatients, aged ≥ 40 years in Bujumbura, Burundi. All patients underwent ankle-brachial index (ABI) measurement and LEAD was diagnosed by ABI ≤ 0.9. The prevalence of LEAD was 17.3% (CI 95% 13.2-22.1). The mean age was 49.6 ± 7.1 years. On multivariable analysis, factors associated with LEAD were hypertension (OR = 2.42; 95% CI 1.10-5.80), and stage IV HIV clinical infection (OR = 4.92, 95% CI 1.19-20.36). This is the first study performed on a large HIV population in Central Africa, reporting high LEAD prevalence. It underlines the influence of HIV infection on peripheral atherosclerosis at latest clinical stages and the need for LEAD screening in HIV-infected patients.
MeSH term(s)	Adult ; Ankle Brachial Index ; Atherosclerosis/diagnosis ; Atherosclerosis/epidemiology ; Atherosclerosis/etiology ; Atherosclerosis/physiopathology ; Burundi/epidemiology ; Cross-Sectional Studies ; Female ; HIV Infections/complications ; Humans ; Hypertension/epidemiology ; Hypertension/etiology ; Lower Extremity ; Male ; Mass Screening ; Middle Aged ; Outpatients ; Prevalence ; Severity of Illness Index
Language	English
Publishing date	2021-04-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-87862-z
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Article ; Online: Artériopathie des membres inférieurs : le traitement.

Desormais, Iléana / Aboyans, Victor / Pesteil, Francis / Lacroix, Philipe

Presse medicale (Paris, France : 1983)

2018 Volume 47, Issue 1, Page(s) 56–61

Abstract: Medical management of peripheral arterial disease (PAD) patients is aimed at limb symptom relief and reducing systemic major adverse events risk. For the first purpose: exercise therapy is recommended in case of claudication; multidisciplinary evaluation ...

Title translation	Peripheral arterial disease: Treatment.
Abstract	Medical management of peripheral arterial disease (PAD) patients is aimed at limb symptom relief and reducing systemic major adverse events risk. For the first purpose: exercise therapy is recommended in case of claudication; multidisciplinary evaluation for surgical options is mandatory in case of critical limb ischaemia. Reducing cardiac and stroke risk can be achieved through: statin prescription in most of the cases; antiplatelet agents in symptomatic PAD patients; cardio-vascular risk factors control.
MeSH term(s)	Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Arteriosclerosis Obliterans/drug therapy ; Disease Management ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Intermittent Claudication/drug therapy ; Ischemia/drug therapy ; Ischemia/surgery ; Leg/blood supply ; Patient Education as Topic ; Peripheral Arterial Disease/complications ; Peripheral Arterial Disease/drug therapy ; Peripheral Arterial Disease/surgery ; Platelet Aggregation Inhibitors/therapeutic use ; Risk Factors ; Stroke/prevention & control ; Thrombophilia/drug therapy ; Thrombophilia/etiology ; Vascular Grafting/methods
Chemical Substances	Angiotensin-Converting Enzyme Inhibitors ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Platelet Aggregation Inhibitors
Language	French
Publishing date	2018-01
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	120943-7
ISSN	2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
ISSN (online)	2213-0276
ISSN	0032-7867 ; 0755-4982 ; 0301-1518
DOI	10.1016/j.lpm.2017.09.019
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Zs.A 794: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Ua VI Zs.87: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Accuracy and Reliability of the Ankle Brachial Index Measurement Using a Multicuff Oscillometric Device Versus the Doppler Method.

Ichihashi, Shigeo / Desormais, Ileana / Hashimoto, Tomoko / Magne, Julien / Kichikawa, Kimihiko / Aboyans, Victor

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

2020 Volume 60, Issue 3, Page(s) 462–468

Abstract: Objective: Ankle brachial index (ABI) is widely used for the diagnosis of lower extremity artery disease (LEAD). The purpose of this prospective study was to validate the diagnostic ability and reproducibility of a four cuff automated oscillometric ... ...

Abstract	Objective: Ankle brachial index (ABI) is widely used for the diagnosis of lower extremity artery disease (LEAD). The purpose of this prospective study was to validate the diagnostic ability and reproducibility of a four cuff automated oscillometric device vs. the Doppler method. Methods: Patients with suspected LEAD or asymptomatic individuals at risk because of the presence two or more cardiovascular risk factors were enrolled. For each patient, Doppler and oscillometric ABI measurements were repeated by two observers to address intra- and interobserver reproducibility. Results: In total, 118 patients were evaluated. The prevalence of Doppler ABI (Dop-ABI) ≤ 0.90 was 45.8%. Taking the Dop-ABI as the reference, the sensitivity, specificity, accuracy, positive and negative predictive values of oscillometric ABI (Osc-ABI) during the first measurement by the first observer were 89.1%, 94.4%, 94.1%, 91.8%, and 92.4%, respectively. The concordance for diagnosing ABI ≤0.90 between methods was excellent (kappa coefficients ranging from 0.80 to 0.88 with different observers). Intra-observer reproducibility assessed by intraclass correlation coefficient (ICC) between methods were 0.94 for observer 1 and 0.96 for observer 2. The intra-observer reproducibility using the same method was also excellent (ICC 0.94, 95% confidence interval [CI] 0.91-0.95) for Dop-ABI and 0.95 (95% CI 0.93-0.97) for Osc-ABI). The ICC for interobserver reproducibility using the same method was 0.95 (95% CI 0.92-0.96) for Dop-ABI and 0.96 (95% CI 0.94-0.97) for Osc-ABI. Conclusion: This study validates the excellent diagnostic performances of a four cuff oscillometric device specifically designed for screening for LEAD. The simple measurement method could therefore be advocated in primary care where fast, easy, and reliable methods are suitable.
MeSH term(s)	Aged ; Aged, 80 and over ; Ankle Brachial Index/instrumentation ; Equipment Design ; Female ; France ; Humans ; Japan ; Lower Extremity/blood supply ; Male ; Middle Aged ; Observer Variation ; Oscillometry/instrumentation ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/diagnostic imaging ; Peripheral Arterial Disease/physiopathology ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Ultrasonography, Doppler
Language	English
Publishing date	2020-08-03
Publishing country	England
Document type	Comparative Study ; Journal Article ; Multicenter Study ; Validation Study
ZDB-ID	1225869-6
ISSN	1532-2165 ; 1078-5884
ISSN (online)	1532-2165
ISSN	1078-5884
DOI	10.1016/j.ejvs.2020.06.013
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Zs.A 2283: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 381: Show issues

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Article ; Online: Estimation of pulse wave velocity in patients with peripheral artery disease: a word of caution.

Aboyans, Victor / Desormais, Ileana / Oueslati, Aida / Lacroix, Philippe

Hypertension research : official journal of the Japanese Society of Hypertension

2016 Volume 39, Issue 1, Page(s) 4–5

MeSH term(s)	Blood Flow Velocity ; Brachial Artery ; Humans ; Peripheral Arterial Disease ; Pulsatile Flow ; Pulse ; Pulse Wave Analysis ; Regression Analysis
Language	English
Publishing date	2016-01
Publishing country	England
Document type	Comment ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1175297-x
ISSN	1348-4214 ; 0916-9636
ISSN (online)	1348-4214
ISSN	0916-9636
DOI	10.1038/hr.2015.115
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Zs.A 3898: Show issues

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Article ; Online: Épidémiologie de l’artériopathie des membres inférieurs.

Aboyans, Victor / Sevestre, Marie-Antoinette / Désormais, Ileana / Lacroix, Philippe / Fowkes, Gerry / Criqui, Michael H

Presse medicale (Paris, France : 1983)

2018 Volume 47, Issue 1, Page(s) 38–46

Abstract: It is estimated that more than 200 million individuals are affected by lower extremity artery disease (LEAD) worldwide. This prevalence has increased between 2000 and 2010 by 25%, especially in low/middle income countries. In France, about one million ... ...

Title translation	Epidemiology of lower extremity artery disease.
Abstract	It is estimated that more than 200 million individuals are affected by lower extremity artery disease (LEAD) worldwide. This prevalence has increased between 2000 and 2010 by 25%, especially in low/middle income countries. In France, about one million people are affected by this condition. Almost two-thirds of patients with LEAD are asymptomatic. This explains the interest of the measurement of the ankle-brachial index (ABI), an objective and harmless diagnostic tool. An ABI≤0.90 is considered as diagnostic for LEAD. The detection of symptomatic LEAD requires standardized questionnaires identifying intermittent claudication. Epidemiological studies on chronic limb-threatening ischemia (CLTI) - the most severe presentation of the disease - are scarce: the prevalence is estimated around 0.5-2.0% after the age of 40, mostly affecting elderly people. Similar to other atherosclerotic diseases, the risk factors are multiple (genetic factors, traditional risk factors, metabolic and inflammatory factors, socioeconomic factors), with different weighs of association as compared to coronary artery diseases. Due to their high prevalence and strength of association, cigarette smoking and hypertension are the most frequent purveyors of this disease in population. Diabetes mellitus is a strong risk factor, and its increasing prevalence contributes to the global epidemics of LEAD. In claudicants, the 5-year amputation risk is estimated at 5%, increasing to 25% at one year in case of CLTI. However, the main risk is related to general cardiovascular events. It is estimated that patients with LEAD present concomitantly coronary and cerebrovascular disease in respectively 50% and 20% of cases. The non-cardiovascular mortality, especially related to cancer, is also higher than in general population. Overall, the control of traditional risk factors has a beneficial effect both for the limb and general prognosis.
MeSH term(s)	Aged ; Cardiovascular Diseases/epidemiology ; Cigarette Smoking/epidemiology ; Comorbidity ; Diabetes Mellitus/epidemiology ; Dyslipidemias/epidemiology ; Female ; France/epidemiology ; Genetic Predisposition to Disease ; Humans ; Hypertension/epidemiology ; Incidence ; Inflammation/epidemiology ; Intermittent Claudication/epidemiology ; Ischemia/epidemiology ; Leg/blood supply ; Male ; Middle Aged ; Neoplasms/epidemiology ; Peripheral Arterial Disease/epidemiology ; Prevalence ; Prognosis ; Risk Factors ; Socioeconomic Factors
Language	French
Publishing date	2018-01
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	120943-7
ISSN	2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
ISSN (online)	2213-0276
ISSN	0032-7867 ; 0755-4982 ; 0301-1518
DOI	10.1016/j.lpm.2018.01.012
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Zs.A 794: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Ua VI Zs.87: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

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Article ; Online: V. Aboyans et al. in response to the article by M. Helfre et al.: Usefulness of a systematic screening of carotid atherosclerosis in asymptomatic people with type 2 diabetes for cardiovascular risk reclassification. Ann Endocrinol (Paris). 2017;78:14-19.

Aboyans, Victor / Desormais, Ileana / Jarlan, Lucile / Teissier, Marie-Pierre / Lacroix, Philippe

Annales d'endocrinologie

2017 Volume 78, Issue 5, Page(s) 484–485

MeSH term(s)	Aspirin/administration & dosage ; Cardiovascular Diseases/prevention & control ; Carotid Artery Diseases/diagnosis ; Diabetes Mellitus, Type 2/complications ; Humans ; Risk Factors
Chemical Substances	Aspirin (R16CO5Y76E)
Language	English
Publishing date	2017-09-01
Publishing country	France
Document type	Letter
ZDB-ID	299-9
ISSN	2213-3941 ; 0003-4266
ISSN (online)	2213-3941
ISSN	0003-4266
DOI	10.1016/j.ando.2017.05.003
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Article ; Online: Epidemiology of coronary artery disease and stroke and associated risk factors in Gaza community -Palestine.

Jamee Shahwan, Amal / Abed, Yehia / Desormais, Ileana / Magne, Julien / Preux, Pierre Marie / Aboyans, Victor / Lacroix, Philippe

PloS one

2019 Volume 14, Issue 1, Page(s) e0211131

Abstract: Aim of study: To determine the prevalence of cardiovascular disease and associated risk factors in the population of Gaza strip in Palestine.: Methods: A cross-sectional stratified cluster sample design was applied in this study. A sample of 2240 ... ...

Abstract	Aim of study: To determine the prevalence of cardiovascular disease and associated risk factors in the population of Gaza strip in Palestine. Methods: A cross-sectional stratified cluster sample design was applied in this study. A sample of 2240 participant (1121 males and 1119 females) aged ≥25 years participated in the study. For each individual, trained staff administered a questionnaire, where all variables of interest followed WHO's STEP wise approach to surveillance chronic disease risk factors (STEPS) (WHO, 2001). Sociodemographic data, anthropometric measure (body mass index, blood pressure), and biochemical test (blood sugar and lipids profiles) were measured. Short International Physical Activity (IPAQ) questionnaire form was used. Bivariate analysis and logistic regression were used with SPSS (version 22.0) to analyze the data. Results: The most common condition was coronary artery disease (8.3%), followed by stroke events (3%). The associated risk factors were obesity (47.8%), hypertension (28.4%), current smoking account for (23.2%), diabetes mellitus (19.1%), high cholesterol level (8.8%), and high triglycerides level (40.2%). Additionally, the proportion of being physical active was found to be low (48.3%); particularly with increasing age. More than 30% of the population has less than 4 days of consumption of fruit and vegetables per week and 65.9% has less than 2 servings per day. Conclusion: The burden of CVDs and their associated risk factors is considerable in Gaza and represents a major public health concern. Effective strategies in management, education and healthcare centers are required for an accurate management and implementation of preventive measure in this area.
MeSH term(s)	Adult ; Age Factors ; Aged ; Coronary Artery Disease/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Middle East/epidemiology ; Risk Factors ; Stroke/epidemiology
Language	English
Publishing date	2019-01-25
Publishing country	United States
Document type	Clinical Trial ; Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0211131
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Article ; Online: Cardiovascular Health and Near Visual Impairment Among Older Adults in the Republic of Congo: A Population-Based Study.

Gbessemehlan, Antoine / Helmer, Catherine / Delcourt, Cécile / Boumediene, Farid / Ndamba-Bandzouzi, Bébène / Mbelesso, Pascal / Samba, Harielle / Kehoua, Gilles / Désormais, Ileana / Lacroix, Philippe / Aboyans, Victor / Dartigues, Jean-François / Houinato, Dismand / Preux, Pierre-Marie / Guerchet, Maëlenn

The journals of gerontology. Series A, Biological sciences and medical sciences

2021 Volume 76, Issue 5, Page(s) 842–850

Abstract: Background: Visual impairment (VI) and determinants of poor cardiovascular health are very common in Sub-Saharan Africa. However, we do not know whether these determinants are associated with VI among older adults in this region. This study aimed at ... ...

Abstract	Background: Visual impairment (VI) and determinants of poor cardiovascular health are very common in Sub-Saharan Africa. However, we do not know whether these determinants are associated with VI among older adults in this region. This study aimed at investigating the association between the determinants of poor cardiovascular health and near VI among older adults living in Congo. Methods: Participants were Congolese adults aged 65 or older included in Epidemiology of Dementia in Central Africa-Follow-up population-based cohort. Near VI was defined as visual acuity less than 20/40 measured at 30 cm. Associations between determinants of poor cardiovascular health collected at baseline and near visual acuity measured at first follow-up were investigated using multivariable logistic regression models. Results: Among the 549 participants included, 378 (68.8%; 95% confidence interval [CI]: 64.9%-72.7%]) had near VI. Of the determinants of poor cardiovascular health explored, we found that having high body mass index of at least 25 kg/m2 (odds ratio [OR] = 2.15; 95% CI: 1.25-3.68), diabetes (OR = 2.12; 95% CI: 1.06-4.25) and hypertension (OR = 1.65; 95% CI: 1.02-2.64) were independently associated with near VI. Conclusions: Several determinants of poor cardiovascular health were associated with near VI in this population. This study suggests that promoting good cardiovascular health could represent a target for VI prevention among older adults.
MeSH term(s)	Aged ; Body Mass Index ; Cardiovascular Diseases/epidemiology ; Cohort Studies ; Congo/epidemiology ; Diabetes Mellitus/epidemiology ; Female ; Follow-Up Studies ; Humans ; Hypertension/epidemiology ; Male ; Visually Impaired Persons
Language	English
Publishing date	2021-01-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1223643-3
ISSN	1758-535X ; 1079-5006
ISSN (online)	1758-535X
ISSN	1079-5006
DOI	10.1093/gerona/glaa304
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