Article ; Online: Urinary immunoglobulins in viral diagnosis
Indian Journal of Medical Research, Vol 155, Iss 1, Pp 11-
An overview
2022 Volume 21
Abstract: Antibody detection by serological methods gained a lot of interest in recent years and has become the backbone of virological diagnosis. Despite the detection of all five classes of immunoglobulins in urine, not much attention has been paid to the use of ...
| Abstract | Antibody detection by serological methods gained a lot of interest in recent years and has become the backbone of virological diagnosis. Despite the detection of all five classes of immunoglobulins in urine, not much attention has been paid to the use of urine as a diagnostic sample to detect viral antibodies. Unlike venipuncture, this non-invasive mode of sample collection can help cover all age groups, especially paediatric and old age patients, where blood collection is difficult. Using urine as a sample is also economical and involves lesser risk in sample collection. The antibodies are found to be stable in urine at room temperature for a prolonged period, which makes the sample transport management easier as well. A few recent studies, have also shown that the detection limit of antibodies in urine is at par with serum or other clinical material. So, the ease in sample collection, availability of samples in large quantity and stability of immunoglobulins in urine for prolonged periods can make urine an ideal sample for viral diagnosis. |
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| Keywords | antibody detection - diagnostics - immunoglobulins - urine - viral diseases ; Medicine ; R |
| Language | English |
| Publishing date | 2022-01-01T00:00:00Z |
| Publisher | Wolters Kluwer Medknow Publications |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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