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Article ; Online: Impact of a Multicomponent Exercise Training Program on Muscle Strength After Bariatric Surgery: A Randomized Controlled Trial.

Boppre, Giorjines / Diniz-Sousa, Florêncio / Veras, Lucas / Bezerra, Andrea / Devezas, Vitor / Preto, John / Santos-Sousa, Hugo / Oliveira, José / Fonseca, Hélder

Obesity surgery

2024 Volume 34, Issue 5, Page(s) 1704–1716

Abstract: Purpose: This study examined the benefits of an 11-months multicomponent exercise program (MEP) on muscular strength (MS) after bariatric surgery.: Methods: Of the 84 randomized patients, 41 participants from the exercise group (EG) and 20 ... ...

Abstract	Purpose: This study examined the benefits of an 11-months multicomponent exercise program (MEP) on muscular strength (MS) after bariatric surgery. Methods: Of the 84 randomized patients, 41 participants from the exercise group (EG) and 20 participants from the control group (CG) were included in the analysis. The EG received supervised MEP for 11 months, starting 1-month post-bariatric surgery (BS) in addition to standard medical care, while the CG received medical care recommendations only. Knee and trunk MS was assessed by isokinetic dynamometry pre-surgery, 1-, 6-, and 12-month post-surgery, while body composition was assessed by dual-energy X-ray absorptiometry. Results: The MEP did not significantly impact absolute MS in the dominant knee and trunk regions at 6- and 12-month post-BS. However, relative MS showed significant improvements. At 6-month post-BS, knee flexion at 60°/s relative to body weight (BW) increased significantly (p = 0.047), as did knee extension at 180°/s relative to BW (p = 0.009), and knee extension at 60°/s relative to total lean mass (p=0.040). At 12-month post-BS, knee flexion at 60°/s relative to BW also significantly improved (p=0.038). Conclusion: While absolute MS was not significantly improved with MEP, this study found significant enhancements in relative MS, particularly in dominant knee flexion post-MEP participation. Further research should explore different exercise intensities and frequencies to optimize postoperative MS recovery post-BS. Clinical trial registration: ClinicalTrials.gov (NCT02843048).
MeSH term(s)	Humans ; Obesity, Morbid/surgery ; Exercise ; Muscle Strength/physiology ; Exercise Therapy ; Bariatric Surgery
Language	English
Publishing date	2024-03-27
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-024-07173-w
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Article: Appendiceal Neuroendocrine Tumours – Experience of One Service

Devezas, Vítor / Barbosa, Laura Elisabete

Journal of Coloproctology

2021 Volume 41, Issue 02, Page(s) 152–155

Abstract: Tumours of the appendix are rare and tend to be diagnosed incidentally, in cases of acute appendicitis. For some authors, appendiceal neuroendocrine tumours (ANETs) are the most frequent neoplasm of the appendix, observed in 0.3% to 0.9% of cases acute ... ...

Abstract	Tumours of the appendix are rare and tend to be diagnosed incidentally, in cases of acute appendicitis. For some authors, appendiceal neuroendocrine tumours (ANETs) are the most frequent neoplasm of the appendix, observed in 0.3% to 0.9% of cases acute appendicitis. The present is a unicentric retrospective study conducted between January 2005 and March 2017. Out of a total of 3,007 surgeries for appendiceal pathologies performed in the adult population at the hospital where the present study was conducted, there were 70 (2.33%) malignant cases, 20 (28.6%) of which were ANETs. The patients had a median age of 44 years (range: 18 to 85 years), and were predominantly women (there were 1.9 times more women than men). In 16 cases (80%), a simple appendicectomy was performed (1 patient was submitted to a right hemicolectomy later). The cases of ANETs had a good prognosis in our series: 85% of the patients are either alive today or were alive after 5 years of follow-up. Despite the fact that ANETs are described as the most frequent tumor of the appendix, this was not confirmed in our series, in which they only represented 28.6% of the cases; adenocarcinoma was the most frequent tumor (65.7%) among our sample.
Keywords	appendix ; neuroendocrine tumors ; carcinoids ; appendectomy ; apêndice ; tumores neuroendócrinos ; carcinoides ; apendicectomia
Language	English
Publishing date	2021-05-24
Publisher	Thieme Revinter Publicações Ltda.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2664477-0
ISSN	2317-6423 ; 2237-9363 ; 2317-6423
ISSN (online)	2317-6423
ISSN	2237-9363 ; 2317-6423
DOI	10.1055/s-0041-1724064
Database	Thieme publisher's database

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Article: A rare case of abdominal pain.

Devezas, Vítor / Canão, Pedro Amoroso / Barbosa, Laura Elisabete

Autopsy & case reports

2019 Volume 9, Issue 2, Page(s) e2019088

Language	English
Publishing date	2019-06-11
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2815488-5
ISSN	2236-1960
ISSN	2236-1960
DOI	10.4322/acr.2019.088
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Article ; Online: The impact of the prognostic nutritional index (PNI) in gastric cancer.

Nogueiro, Jorge / Santos-Sousa, Hugo / Pereira, André / Devezas, Vítor / Fernandes, Cristina / Sousa, Fabiana / Fonseca, Telma / Barbosa, Elisabete / Barbosa, José Adelino

Langenbeck's archives of surgery

2022 Volume 407, Issue 7, Page(s) 2703–2714

Abstract: Background: Regarding the assessment of patients' immune and nutritional status, prognostic nutritional index (PNI) has been reported as a predictive marker for surgical outcomes in various types of cancer. The aim of our study was to evaluate the ... ...

Abstract	Background: Regarding the assessment of patients' immune and nutritional status, prognostic nutritional index (PNI) has been reported as a predictive marker for surgical outcomes in various types of cancer. The aim of our study was to evaluate the effect of PNI in prognosis of gastric cancer patients submitted to curative-intent resectional surgery. Material and methods: A retrospective analysis with 637 gastric cancer cases submitted to curative-intent surgery, between 2010 and 2017, in an upper GI surgery unit. We analyzed 396 patients that met the inclusion criteria for this study. The median follow-up was 37 (0-113) months. Results: According to Youden's method, the optimal PNI cutoff for OS was 41.625 (sensitivity 89.3% and specificity 41.3%). OS was significantly shorter in the lower-PNI group of patients when compared to the higher-PNI group (40.26 vs 77.49 months; p < 0.001). Higher PNI had a positive impact on OS in univariable analysis. When adjusted to pStage, higher PNI was still significantly associated with better OS (HR 0.405; CI 95% 0.253-0.649; p < 0.001). Regarding DFS, higher PNI was associated with better DFS (HR 0.421; CI 95% 0.218-0.815; p = 0.010). Higher-PNI group had a protective effect regarding postoperative morbidity and mortality. Conclusions: In this cohort, PNI was disclosed to significantly impact GC patients' OS and DFS, including in multivariable analysis when adjusting for classical prognostic features. PNI can be used to predict patients at increased risk of postoperative morbidity and mortality. This index may be of use in identifying candidate patients who would benefit from perioperative nutritional support to improve surgical outcomes.
MeSH term(s)	Humans ; Nutrition Assessment ; Stomach Neoplasms/surgery ; Gastrectomy/adverse effects ; Prognosis ; Retrospective Studies ; Nutritional Status
Language	English
Publishing date	2022-08-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1423681-3
ISSN	1435-2451 ; 1435-2443
ISSN (online)	1435-2451
ISSN	1435-2443
DOI	10.1007/s00423-022-02627-0
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Article ; Online: Effects of a supervised exercise training on body composition after bariatric surgery: a randomized controlled trial.

Boppre, Giorjines / Borges, Lara Pereira Saraiva Leão / Diniz-Sousa, Florêncio / Veras, Lucas / Devezas, Vitor / Preto, John / Santos-Sousa, Hugo / da Costa, Teresa Helena Macedo / Oliveira, José / Fonseca, Hélder

Obesity (Silver Spring, Md.)

2023 Volume 31, Issue 11, Page(s) 2750–2761

Abstract: Objective: This study aimed to determine the effects of a multicomponent exercise intervention during the first year post-bariatric surgery (BS) on body composition, weight loss (WL), energy expenditure, and nutrient intake.: Methods: A total of 84 ... ...

Abstract	Objective: This study aimed to determine the effects of a multicomponent exercise intervention during the first year post-bariatric surgery (BS) on body composition, weight loss (WL), energy expenditure, and nutrient intake. Methods: A total of 84 patients were included in this study and were randomly assigned to either an exercise group (n = 41) or a control group (n = 20). The exercise group participated in a multicomponent exercise program that began 1-month post-BS, whereas the control group received only standard medical care post-BS. Body composition was assessed by dual-energy x-ray absorptiometry, and physical activity energy expenditure was assessed by accelerometers. Nutritional intake was assessed through a 4-day food diary. Results: A total of 6-months post-BS, exercise was found to be effective in mitigating the loss of lower-limb and appendicular lean mass (LM), as well as favoring trunk fat mass (FM) loss. Moreover, it further decreased percent FM and promoted additional excess WL. After 12 months, exercise not only reduced waist circumference but also helped to lessen the loss of total, trunk, and appendicular LM. Conclusions: Exercise further induced trunk fat mass, percent FM, excess WL, and waist circumference reductions. Moreover, exercise attenuated the loss of total and regional LM.
MeSH term(s)	Humans ; Body Composition ; Exercise ; Bariatric Surgery ; Weight Loss ; Energy Intake
Language	English
Publishing date	2023-04-04
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2230457-5
ISSN	1930-739X ; 1071-7323 ; 1930-7381
ISSN (online)	1930-739X
ISSN	1071-7323 ; 1930-7381
DOI	10.1002/oby.23894
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Article ; Online: Using Raw Accelerometer Data to Predict High-Impact Mechanical Loading.

Veras, Lucas / Diniz-Sousa, Florêncio / Boppre, Giorjines / Devezas, Vítor / Santos-Sousa, Hugo / Preto, John / Vilas-Boas, João Paulo / Machado, Leandro / Oliveira, José / Fonseca, Hélder

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 4

Abstract: The purpose of this study was to develop peak ground reaction force (pGRF) and peak loading rate (pLR) prediction equations for high-impact activities in adult subjects with a broad range of body masses, from normal weight to severe obesity. A total of ... ...

Abstract	The purpose of this study was to develop peak ground reaction force (pGRF) and peak loading rate (pLR) prediction equations for high-impact activities in adult subjects with a broad range of body masses, from normal weight to severe obesity. A total of 78 participants (27 males; 82.4 ± 20.6 kg) completed a series of trials involving jumps of different types and heights on force plates while wearing accelerometers at the ankle, lower back, and hip. Regression equations were developed to predict pGRF and pLR from accelerometry data. Leave-one-out cross-validation was used to calculate prediction accuracy and Bland-Altman plots. Body mass was a predictor in all models, along with peak acceleration in the pGRF models and peak acceleration rate in the pLR models. The equations to predict pGRF had a coefficient of determination (R
MeSH term(s)	Adult ; Male ; Humans ; Acceleration ; Accelerometry ; Ankle Joint ; Back ; Research Design
Language	English
Publishing date	2023-02-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23042246
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Article ; Online: Accelerometer-based prediction of skeletal mechanical loading during walking in normal weight to severely obese subjects.

Veras, L / Diniz-Sousa, F / Boppre, G / Devezas, V / Santos-Sousa, H / Preto, J / Vilas-Boas, J P / Machado, L / Oliveira, J / Fonseca, H

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

2020 Volume 31, Issue 7, Page(s) 1239–1250

Abstract: There is no objective way to monitor mechanical loading characteristics during exercise for bone health improvement. We developed accelerometry-based equations to predict ground reaction force (GRF) and loading rate (LR) in normal weight to severely ... ...

Abstract	There is no objective way to monitor mechanical loading characteristics during exercise for bone health improvement. We developed accelerometry-based equations to predict ground reaction force (GRF) and loading rate (LR) in normal weight to severely obese subjects. Equations developed had a high and moderate accuracy for GRF and LR prediction, respectively, thereby representing an accessible way to determine mechanical loading characteristics in clinical settings. Introduction: There is no way to objectively prescribe and monitor exercise for bone health improvement in obese patients based on mechanical loading characteristics. We aimed to develop accelerometry-based equations to predict peak ground reaction forces (pGRFs) and peak loading rate (pLR) on normal weight to severely obese subjects. Methods: Sixty-four subjects (45 females; 84.6 ± 21.7 kg) walked at different speeds (2-6 km·h Results: Body mass and peak acceleration were included for pGRF prediction and body mass and peak acceleration transient rate for pLR prediction. All pGRF equation coefficients of determination were above 0.89, a good agreement between actual and predicted pGRFs, with a mean absolute percent error (MAPE) below 6.7%. No significant differences were observed between actual and predicted pGRFs at each walking speed. Accuracy indices from our equations were better than previously developed equations for normal weight subjects, namely a MAPE approximately 3 times smaller. All pLR prediction equations presented a lower accuracy compared to those developed to predict pGRF. Conclusion: Walking pGRF and pLR in normal weight to severely obese subjects can be predicted with moderate to high accuracy by accelerometry-based equations, representing an easy and accessible way to determine mechanical loading characteristics in clinical settings.
MeSH term(s)	Acceleration ; Accelerometry ; Exercise ; Female ; Humans ; Obesity ; Walking
Language	English
Publishing date	2020-01-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1064892-6
ISSN	1433-2965 ; 0937-941X
ISSN (online)	1433-2965
ISSN	0937-941X
DOI	10.1007/s00198-020-05295-2
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Article ; Online: Effects of a Multicomponent Exercise Training Program on Balance Following Bariatric Surgery.

Diniz-Sousa, Florêncio / Granja, Tiago / Boppre, Giorjines / Veras, Lucas / Devezas, Vítor / Santos-Sousa, Hugo / Preto, John / Machado, Leandro / Vilas Boas, Joao Paulo / Oliveira, Jose / Fonseca, Hélder

International journal of sports medicine

2022 Volume 43, Issue 9, Page(s) 818–824

Abstract: Patients who undergo bariatric surgery (BS) have an increased risk of falls. Our aim was to determine if a multicomponent exercise intervention after BS improves balance. Eighty-four patients with obesity enrolled for BS were recruited and 1 month after ... ...

Abstract	Patients who undergo bariatric surgery (BS) have an increased risk of falls. Our aim was to determine if a multicomponent exercise intervention after BS improves balance. Eighty-four patients with obesity enrolled for BS were recruited and 1 month after BS randomly allocated to a control (CG; standard medical care) or exercise group (EG; exercise plus standard medical care) consisting of a supervised multicomponent training program (3d/week; 75 min/session; 5 months). Anthropometry, lower limb muscle strength (isokinetic dynamometer), vitamin D (ELISA) and balance in bipedal stance (force platform) were assessed pre-BS, 1 month and 6 months post-BS. One month post-BS, significant balance improvements were observed, namely in antero-posterior center of gravity (CoG) displacement and velocity, and medio-lateral and total CoG velocity. Between 1- and 6-months post-BS, improvements in balance were observed only in the EG, with a significant treatment effect on CoG displacement area and antero-posterior CoG displacement. No significant differences were observed between EG and CG over time in any of the anthropometric, muscle strength, and vitamin D variables assayed. In conclusion, a multicomponent exercise intervention program improves some balance parameters in patients with severe obesity following BS and therefore should be part of post-BS follow-up care as a potential strategy to reduce falls and associated injuries.
MeSH term(s)	Accidental Falls/prevention & control ; Bariatric Surgery ; Exercise/physiology ; Exercise Therapy ; Humans ; Muscle Strength/physiology ; Postural Balance/physiology ; Vitamin D
Chemical Substances	Vitamin D (1406-16-2)
Language	English
Publishing date	2022-04-13
Publishing country	Germany
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	603122-5
ISSN	1439-3964 ; 0172-4622 ; 0943-917X
ISSN (online)	1439-3964
ISSN	0172-4622 ; 0943-917X
DOI	10.1055/a-1766-5803
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Article ; Online: Mechanical loading prediction through accelerometry data during walking and running.

Veras, Lucas / Diniz-Sousa, Florêncio / Boppre, Giorjines / Resende-Coelho, Ana / Moutinho-Ribeiro, Edgar / Devezas, Vítor / Santos-Sousa, Hugo / Preto, John / Vilas-Boas, João Paulo / Machado, Leandro / Oliveira, José / Fonseca, Hélder

European journal of sport science

2022 Volume 23, Issue 8, Page(s) 1518–1527

Abstract: Currently, there is no way to assess mechanical loading variables such as peak ground reaction forces (pGRF) and peak loading rate (pLR) in clinical settings. The purpose of this study was to develop accelerometry-based equations to predict both pGRF and ...

Abstract	Currently, there is no way to assess mechanical loading variables such as peak ground reaction forces (pGRF) and peak loading rate (pLR) in clinical settings. The purpose of this study was to develop accelerometry-based equations to predict both pGRF and pLR during walking and running. One hundred and thirty one subjects (79 females; 76.9 ± 19.6 kg) walked and ran at different speeds (2-14 km·h
MeSH term(s)	Female ; Humans ; Walking ; Accelerometry ; Running ; Ankle ; Ankle Joint ; Biomechanical Phenomena
Language	English
Publishing date	2022-08-11
Publishing country	England
Document type	Journal Article
ISSN	1536-7290
ISSN (online)	1536-7290
DOI	10.1080/17461391.2022.2102437
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Article: Large desmoid tumors in familial adenomatous polyposis: a successful outcome.

Devezas, Vítor / Barbosa, Laura Elisabete / Ramalho, Rosa / Sarmento, Cristina / Maia, José Costa

Autopsy & case reports

2018 Volume 8, Issue 4, Page(s) e2018045

Abstract: Desmoid tumors develop from connective tissue, fasciae, and aponeuroses, and may occur in the context of familial adenomatous polyposis or may arise sporadically; also, they may be extra-abdominal, intra-abdominal, or located in the abdominal wall. These ...

Abstract	Desmoid tumors develop from connective tissue, fasciae, and aponeuroses, and may occur in the context of familial adenomatous polyposis or may arise sporadically; also, they may be extra-abdominal, intra-abdominal, or located in the abdominal wall. These benign tumors have a great aggressiveness with a high rate of local recurrence. Familial adenomatous polyposis is an inherited condition with autosomal dominant transmission, and is characterized by the development of multiple colonic and rectal adenomatous polyps, as well as desmoid tumors. We present the case of a 54-year-old woman with germline
Language	English
Publishing date	2018-09-26
Publishing country	Brazil
Document type	Case Reports
ZDB-ID	2815488-5
ISSN	2236-1960
ISSN	2236-1960
DOI	10.4322/acr.2018.045
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