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Article ; Online: Late Systemic Right Ventricle Failure: Moving Toward a Real-Time Prediction Tool.

Karamlou, Tara / Devlin, Paul J / Hammoud, Miza Salim

Journal of the American College of Cardiology

2022 Volume 80, Issue 10, Page(s) 964–966

MeSH term(s)	Heart Failure/diagnosis ; Heart Failure/therapy ; Heart Ventricles/diagnostic imaging ; Humans ; Transposition of Great Vessels
Language	English
Publishing date	2022-09-01
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2022.06.021
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Zs.MO 196: Show issues

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Article ; Online: Commentary: Food for Thought.

Devlin, Paul J / Mehta, Christopher K

Seminars in thoracic and cardiovascular surgery

2020 Volume 33, Issue 1, Page(s) 116–117

MeSH term(s)	Cardiac Surgical Procedures ; Food ; Humans ; Prospective Studies
Language	English
Publishing date	2020-09-20
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	1038278-1
ISSN	1532-9488 ; 1043-0679
ISSN (online)	1532-9488
ISSN	1043-0679
DOI	10.1053/j.semtcvs.2020.09.021
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Zs.A 2747: Show issues

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Article ; Online: Commentary: "Fact-checking" the authors: Assessing understandability or awareness in cardiothoracic papers.

Karamlou, Tara / Devlin, Paul J

The Journal of thoracic and cardiovascular surgery

2020 Volume 163, Issue 3, Page(s) 1125–1126

Language	English
Publishing date	2020-11-06
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2020.11.002
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Uk I Zs.104: Show issues

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Article ; Online: The Congenital Heart Surgeons' Society Kirklin/Ashburn Fellowship: The Fellows' Perspective.

Jegatheeswaran, Anusha / Argo, Madison B / Devlin, Paul J / Callahan, Connor P / Meza, James M / Wilder, Travis J / Hickey, Edward J / Karamlou, Tara

World journal for pediatric & congenital heart surgery

2023 Volume 14, Issue 5, Page(s) 575–586

Abstract: Since its establishment in 2001, the Congenital Heart Surgeons' Society John W. Kirklin/David Ashburn Fellowship has contributed substantially to the field of congenital heart surgery research while simultaneously training the next generation of surgeon- ...

Abstract	Since its establishment in 2001, the Congenital Heart Surgeons' Society John W. Kirklin/David Ashburn Fellowship has contributed substantially to the field of congenital heart surgery research while simultaneously training the next generation of surgeon- scientists. To date, ten fellows (and counting) have successfully completed this rigorous training, producing over 40 published articles focused on longitudinal outcomes from the various Congenital Heart Surgeons' Society cohorts. As the Kirklin/Ashburn Fellowship expands and additional fellows matriculate, its legacy, the network of support, and the contribution to congenital heart surgery research will undoubtedly hold strong.
MeSH term(s)	Humans ; Fellowships and Scholarships ; Surgeons ; Heart Defects, Congenital/surgery
Language	English
Publishing date	2023-10-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2550261-X
ISSN	2150-136X ; 2150-1351
ISSN (online)	2150-136X
ISSN	2150-1351
DOI	10.1177/21501351231190087
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Article ; Online: Neighborhood Socioeconomic Status and Readmission in Acute Type A Aortic Dissection Repair.

Liu, Tom / Devlin, Paul J / Whippo, Beth / Vassallo, Patricia / Hoel, Andrew / Pham, Duc Thinh / Johnston, Douglas R / Chris Malaisrie, Sukit / Mehta, Christopher K

The Journal of surgical research

2024 Volume 296, Page(s) 772–780

Abstract: Introduction: We examined the association of socioeconomic status as defined by median household income quartile (MHIQ) with mortality and readmission patterns following open repair of acute type A aortic dissection (ATAAD) in a nationally ... ...

Abstract	Introduction: We examined the association of socioeconomic status as defined by median household income quartile (MHIQ) with mortality and readmission patterns following open repair of acute type A aortic dissection (ATAAD) in a nationally representative registry. Methods: Adults who underwent open repair of ATAAD were selected using the US Nationwide Readmissions Database and stratified by MHIQ. Patients were selected based on diagnostic and procedural codes. The primary endpoint was 30-d readmission. Results: Between 2016 and 2019, 10,288 individuals (65% male) underwent open repair for ATAAD. Individuals in the lowest income quartile were younger (median: 60 versus 64, P < 0.05) but had greater Elixhauser comorbidity burden (5.9 versus 5.7, P < 0.05). Across all groups, in-hospital mortality was approximately 15% (P = 0.35). On multivariable analysis adjusting for baseline comorbidity burden, low socioeconomic status was associated with increased readmission at 90 d, but not at 30 d. Concomitant renal disease (odds ratio [OR], 1.68; P < 0.001), pulmonary disease (OR, 1.26; P < 0.001), liver failure (OR 1.2, P = 0.04), and heart failure (OR, 1.17; P < 0.001) were all associated with readmission at 90 d. The primary indication for readmission was most commonly cardiac (33%), infectious (16.5%), and respiratory (9%). Conclusions: In patients who undergo surgery for ATAAD, lower MHIQ was associated with higher odds of readmission following open repair. While early readmission for individuals living in the lowest income communities is likely attributable to greater baseline comorbidity burden, we observed that 90-d readmission rates are associated with lower MHIQ regardless of comorbidity burden. Further investigation is required to determine which patient-level and system-level interventions are needed to reduce readmissions in the immediate postoperative period for resource poor areas.
MeSH term(s)	Adult ; Humans ; Male ; Female ; Patient Readmission ; Risk Factors ; Comorbidity ; Social Class ; Aortic Dissection/epidemiology ; Aortic Dissection/surgery ; Retrospective Studies
Language	English
Publishing date	2024-02-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2023.12.049
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Zs.A 178: Show issues

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Article ; Online: Fracture of dual lumen cannula leading to cerebrovascular accident in a patient supported with ECMO.

Argaw, Salem T / Devlin, Paul J / Clark, James A / Garza-Castillon, Rafael / Kurihara, Chitaru / Bharat, Ankit

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

2022 Volume 25, Issue 3, Page(s) 279–282

Abstract: Extended duration extracorporeal membrane oxygenation (ECMO), using dual-lumen cannulas, is being used with increased frequency to support patients, including those with COVID-19; both as a bridge to transplant and lung recovery. During such an extended ... ...

Abstract	Extended duration extracorporeal membrane oxygenation (ECMO), using dual-lumen cannulas, is being used with increased frequency to support patients, including those with COVID-19; both as a bridge to transplant and lung recovery. During such an extended duration of support, there are several factors that might lead to the attrition of the physical structure of the ECMO cannulas, predisposing them to the risk of fracture. Although rare, fracture of the ECMO cannula can be a potentially lethal event. Here, we present a case where fracture of a dual lumen cannula during veno-venous (VV) ECMO support resulted in a cerebrovascular accident. We discuss the potential contributing factors and suggest steps to mitigate the risks for such a complication.
MeSH term(s)	COVID-19 ; Cannula ; Extracorporeal Membrane Oxygenation ; Humans ; Stroke
Language	English
Publishing date	2022-01-18
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	1463555-0
ISSN	1619-0904 ; 1434-7229
ISSN (online)	1619-0904
ISSN	1434-7229
DOI	10.1007/s10047-021-01306-z
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Zs.A 5024: Show issues

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Article ; Online: Senior and Junior Rugby League Players Improve Lower-Body Strength and Power Differently During a Rugby League Season.

Wade, Jarrod A / Fuller, Joel T / Devlin, Paul J / Doyle, Tim L A

Journal of strength and conditioning research

2020 Volume 36, Issue 5, Page(s) 1367–1372

Abstract: Abstract: Wade, JA, Fuller, JT, Devlin, PJ, and Doyle, TLA. Senior and junior rugby league players improve lower-body strength and power differently during a rugby league season. J Strength Cond Res 36(5): 1367-1372, 2022-This investigation evaluated ... ...

Abstract	Abstract: Wade, JA, Fuller, JT, Devlin, PJ, and Doyle, TLA. Senior and junior rugby league players improve lower-body strength and power differently during a rugby league season. J Strength Cond Res 36(5): 1367-1372, 2022-This investigation evaluated lower-body strength and power changes across a rugby league season in elite junior and senior athletes. Twenty-five senior and 20 junior rugby league players performed an isometric midthigh pull and countermovement jump at 3 time points in a National Rugby League training season (mid-preseason, end-preseason, and in-season). Linear fixed-effects models were used to compare isometric midthigh pull force and countermovement jump power between player experience groups (senior vs. junior) across the season phases (mid-preseason vs. end-preseason vs. and in-season). Cohen's effect sizes (ES) with 95% confidence intervals were calculated for pairwise comparisons. For senior players, absolute and relative strength (ES = 0.38, p < 0.007) and power (ES = 0.64, p < 0.008) increases were observed at end-preseason compared with mid-preseason, but there were no changes in-season (ES = 0.02, p > 0.571). For junior players, strength did not change (ES < 0.01, p > 0.738) and absolute power decreased (ES = 0.29, p < 0.014) at end-preseason compared with mid-preseason; large increases were evident for absolute and relative strength (ES = 1.43, p < 0.001) and power (ES = 0.62, p < 0.001) in-season. This research demonstrates senior and junior rugby league players exhibit unique patterns of improvements in lower-body strength and power across different phases of the season. This highlights the importance for training programs to differ between junior and senior athletes and target different physical qualities for both groups at different times of the season, thus providing guidance for strength and conditioning coaches.
MeSH term(s)	Athletes ; Football ; Humans ; Rugby ; Seasons
Language	English
Publishing date	2020-06-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000003652
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Zs.A 6263: Show issues

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Article ; Online: Contemporary Applications and Outcomes of Pulmonary Artery Banding: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database.

Devlin, Paul J / Argo, Madison / Habib, Robert H / McCrindle, Brian W / Jegatheeswaran, Anusha / Jacobs, Marshall L / Jacobs, Jeffrey P / Backer, Carl L / Overman, David M / Karamlou, Tara

The Annals of thoracic surgery

2023 Volume 117, Issue 1, Page(s) 128–135

Abstract: Background: Pulmonary artery banding (PAB) in isolation or combined with a congenital cardiac surgical procedure is common and has important mortality. We aimed to determine patient characteristics, clinical outcomes, variation in clinical outcomes by ... ...

Abstract	Background: Pulmonary artery banding (PAB) in isolation or combined with a congenital cardiac surgical procedure is common and has important mortality. We aimed to determine patient characteristics, clinical outcomes, variation in clinical outcomes by diagnoses, and center variation in PAB use. Methods: Using The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD), this study evaluated outcomes of patients undergoing PAB across diagnoses, participating centers, and additional procedures. Patients were identified by procedure and diagnosis codes from 2016 to 2019. We separated patients into groups of main and bilateral PAB and described their outcomes, focusing on patients with main PAB. Results: This study identified 3367 PAB procedures from 2016 to 2019 (3% of all STS CHSD cardiovascular cases during this period): 2677 main PAB, 690 bilateral PAB. Operative mortality was 8% after main PAB and 26% after bilateral PAB. There was significant variation in use of main PAB by center, with 115 centers performing at least 1 main PAB procedure (range, 1-134; Q1-Q3, 8-33). For patients with main PAB, there were substantial differences in mortality, depending on timing of main PAB relative to other procedures. The highest operative mortality (25%; P < .0001) was in patients who underwent main PAB after another separate procedure during their admission, with extracorporeal membrane oxygenation being the most frequent preceding procedure. Conclusions: PAB is a frequently used congenital cardiac procedure with high mortality and variation in use across centers. Outcomes vary widely by banding type and patient diagnosis. Main PAB after cardiac surgical procedures, especially extracorporeal membrane oxygenation, is associated with very high operative mortality.
MeSH term(s)	Humans ; Treatment Outcome ; Pulmonary Artery/surgery ; Cardiac Surgical Procedures ; Databases, Factual ; Heart Defects, Congenital/surgery ; Surgeons ; Thoracic Surgery
Language	English
Publishing date	2023-09-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2023.09.020
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Zs.A 252: Show issues

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Article ; Online: Bleeding risk associated with combination thromboprophylaxis therapy is low for patients with coronary artery aneurysms after Kawasaki disease.

Low, Tisiana / Jegatheeswaran, Anusha / Devlin, Paul J / Chahal, Nita / Brandão, Leonardo R / McCrindle, Brian W

International journal of cardiology

2020 Volume 321, Page(s) 6–11

Abstract: Background: Kawasaki disease (KD) may lead to coronary artery aneurysms (CAA) with potential for thrombosis. We aimed to determine the bleeding risk during thromboprophylaxis regimens with dual and triple therapy.: Methods: KD patients with medium to ...

Abstract	Background: Kawasaki disease (KD) may lead to coronary artery aneurysms (CAA) with potential for thrombosis. We aimed to determine the bleeding risk during thromboprophylaxis regimens with dual and triple therapy. Methods: KD patients with medium to large CAAs receiving combination thromboprophylaxis therapy (dual or triple therapy with acetylsalicylic acid (ASA), clopidogrel, low molecular weight heparin (LMWH) or warfarin) were reviewed (1979-2017). Treatment periods <30 days were excluded. Bleeding events were classified using the Bleeding Academic Research Consortium (BARC) Score. The incidence of bleeding events per patient year of exposure was determined for each regimen. Results: n = 98 of 3022 KD (23 females:75 males) were included. Median age at diagnosis was 2.6 years (IQR: 0.6-6.2), median maximum CAA z-score was 18.0 (range: 5-65.5, IQR: 10.8-28.0, m = 6) and median follow-up duration was 6.5 years (IQR: 2.5-20.2). The incidence of type ≥2 bleeds per patient-year for each regimen was 0 (ASA + clopidogrel+LMWH), 0.03 (ASA + clopidogrel), 0.06 (ASA + warfarin), 0.06 (ASA + clopidogrel+warfarin), and 0.1 (ASA + LMWH) in ascending order. 31 bleeding events requiring medical attention (type ≥2) occurred in 30 patients (median age 7.8 years). Of the 17 type ≥2 bleeds on warfarin with an International Normalised Ratio (INR) available, 13 occurred with an INR >3. For patients receiving triple therapy (dual antiplatelet with anticoagulant), there were 57 bleeding events over 20 treatment periods. Conclusions: The overall bleeding risk was low in KD patients receiving combination thromboprophylaxis, and not significantly different across all regimens. Type ≥2 bleeding events that occurred on warfarin were most frequently associated with high INR values.
MeSH term(s)	Anticoagulants/adverse effects ; Child ; Coronary Vessels ; Drug Therapy, Combination ; Female ; Heparin, Low-Molecular-Weight/therapeutic use ; Humans ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Mucocutaneous Lymph Node Syndrome/drug therapy ; Platelet Aggregation Inhibitors/adverse effects ; Venous Thromboembolism/drug therapy
Chemical Substances	Anticoagulants ; Heparin, Low-Molecular-Weight ; Platelet Aggregation Inhibitors
Language	English
Publishing date	2020-07-19
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2020.07.022
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Zs.A 1673: Show issues

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Article ; Online: 24-Year Results of Nonfenestrated Extracardiac Fontan Including Fontan Conversions.

Stephens, Elizabeth H / Talwar, Abhinav A / Devlin, Paul J / Eltayeb, Osama / Mongé, Michael C / Tsao, Sabrina / Backer, Carl L

The Annals of thoracic surgery

2020 Volume 112, Issue 2, Page(s) 619–625

Abstract: Background: There is active debate regarding the optimal method of Fontan palliation. In light of this, we reviewed our experience with the nonfenestrated extracardiac Fontan including Fontan conversion.: Methods: We performed a retrospective review ... ...

Abstract	Background: There is active debate regarding the optimal method of Fontan palliation. In light of this, we reviewed our experience with the nonfenestrated extracardiac Fontan including Fontan conversion. Methods: We performed a retrospective review of all nonfenestrated extracardiac Fontan and Fontan conversion operations at our institution from December 1, 1994 to December 31, 2018. Standard demographic data were collected, including underlying anatomy, preoperative ventricular and valvular function, operative details, perioperative data, and clinical outcomes. Statistical analysis included comparison between initial extracardiac Fontan patients and Fontan conversions, as well as analysis of risk factors for adverse outcomes. Results: There were 341 patients with an overall operative mortality of 4 patients (1.2%). Of these, 193 were extracardiac nonfenestrated Fontan completion operations (57%) and 148 were Fontan conversions (43%). Length of stay was 11 days (SD, 6 days) with ventilator duration of 28 hours (SD, 26 hours). Six of the completion Fontan patients (3%) required Fontan takedown at a median time of 2.5 days. Upon multivariable analysis, risk factors associated with adverse events (mortality, Fontan takedown, and/or transplant) included increased cardiopulmonary bypass time, preoperative decreased dominant ventricular function, and length of stay. Kaplan-Meier curves demonstrated that mild or greater preoperative ventricular dysfunction decreased survival as well as freedom from adverse events for both initial extracardiac Fontan and Fontan conversion patients. Conclusions: Over the past 24 years, our strategy of nonfenestrated extracardiac Fontan has achieved low operative mortality for both initial Fontan and Fontan conversion. There is a steady attrition of Fontan patients to cardiac transplantation; the key risk factor is preoperative ventricular dysfunction.
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Fontan Procedure/methods ; Forecasting ; Heart Defects, Congenital/surgery ; Humans ; Male ; Retrospective Studies ; Risk Factors ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2020-08-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	211007-6
ISSN	1552-6259 ; 0003-4975
ISSN (online)	1552-6259
ISSN	0003-4975
DOI	10.1016/j.athoracsur.2020.06.019
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