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  1. Article ; Online: Standing on the Shoulders of Giants!

    Dewan, Pooja

    Indian pediatrics

    2024  Volume 61, Issue 1, Page(s) 8–9

    Language English
    Publishing date 2024-01-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sublingual Methylcobalamin in Children With Vitamin B12 Deficiency Anemia: Author's Response.

    Dewan, Pooja

    Indian pediatrics

    2023  Volume 60, Issue 12, Page(s) 1046–1047

    MeSH term(s) Child ; Humans ; Vitamin B 12/therapeutic use ; Vitamin B 12 Deficiency/complications ; Vitamin B 12 Deficiency/drug therapy ; Anemia
    Chemical Substances mecobalamin (BR1SN1JS2W) ; Vitamin B 12 (P6YC3EG204)
    Language English
    Publishing date 2023-12-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Three vs Four Dose Schedule of Hepatitis-B Vaccine in HIV-infected Children: Authors' Reply.

    Dewan, Pooja

    Indian pediatrics

    2021  Volume 58, Issue 5, Page(s) 493–494

    MeSH term(s) Child ; HIV Infections ; Hepatitis ; Hepatitis B Antibodies ; Hepatitis B Vaccines ; Humans ; Immunization Schedule
    Chemical Substances Hepatitis B Antibodies ; Hepatitis B Vaccines
    Language English
    Publishing date 2021-04-20
    Publishing country India
    Document type Journal Article ; Comment
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Familial hypercholestrolemia: clinical examination holds the key!

    Dewan, Pooja / Grover, Chander

    Pediatric endocrinology, diabetes, and metabolism

    2022  Volume 27, Issue 3, Page(s) 209–212

    Abstract: Familial hypercholesterolemia is a rare genetic disease, although it is amongst the commonest dyslipidemias. It characterized by raised cholesterol levels and normal triglyceride levels. Childhood presentation of familial hypercholesterolemia can cause ... ...

    Title translation Rodzinna hipercholesterolemia. Badanie kliniczne kluczem do sukcesu diagnostycznego.
    Abstract Familial hypercholesterolemia is a rare genetic disease, although it is amongst the commonest dyslipidemias. It characterized by raised cholesterol levels and normal triglyceride levels. Childhood presentation of familial hypercholesterolemia can cause early atherosclerotic plaque deposition in arteries and a markedly increased risk of coronary heart disease (CHD) at a young age. A thorough clinical examination, including identification of signs like cutaneous lesions and careful eye examination, can clinch the diagnosis.
    MeSH term(s) Child ; Coronary Disease ; Dyslipidemias ; Humans ; Hyperlipoproteinemia Type II/diagnosis ; Hyperlipoproteinemia Type II/genetics ; Rare Diseases
    Language English
    Publishing date 2022-04-15
    Publishing country Poland
    Document type Case Reports
    ZDB-ID 2617120-X
    ISSN 2083-8441 ; 2083-8441
    ISSN (online) 2083-8441
    ISSN 2083-8441
    DOI 10.5114/pedm.2021.107714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hematological Indices for Identifying Adverse Outcomes in Children Admitted to Pediatric ICUs.

    Mahalingam, Sivakumar / Bhaskar, Vikram / Batra, Prerna / Dewan, Pooja / Gogoi, Priyanka

    Cureus

    2024  Volume 16, Issue 2, Page(s) e53744

    Abstract: Background: The pediatric ICU (PICU) is a specialized area where critically sick children are managed. The mortality rates in PICUs are higher in developing countries as compared to developed nations. Many of these deaths could be prevented if very sick ...

    Abstract Background: The pediatric ICU (PICU) is a specialized area where critically sick children are managed. The mortality rates in PICUs are higher in developing countries as compared to developed nations. Many of these deaths could be prevented if very sick children were identified soon after they arrived at the health facility. Hematological indices like platelet lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR) have been frequently used in adults as indicators of mortality. However, their use in the pediatric population is limited due to a lack of validated reference intervals.
    Objective: The objective of the study is to assess the role of hematological indices in identifying adverse outcomes in terms of mortality in children admitted to the PICU.
    Materials and methods: It is a prospective, observational study done at a tertiary care hospital. All children aged one year to 12 years admitted to the PICU were enrolled in the study. A sample for complete blood count was taken within one hour of admission to the PICU. Children who had received blood products in the last two months, those on chronic medications (>two weeks) that can affect bone marrow cellularity, and known cases of hematological disorders such as megaloblastic anemia, hematological malignancies, immune thrombocytopenia, and aplastic anemia were excluded from the study. PLR, NLR, and platelets to mean platelet volume ratio (PLT/MPV) were determined and compared among the survivors and non-survivors.
    Results:  Out of 275 enrolled patients, 119 (43.3%) patients expired during the study period. While PLR had high sensitivity and NLR had high specificity (85.71% and 92.31%, respectively) for predicting mortality, none of these parameters had a good area under the curve (AUC) in our study. PLT/MPV of ≥32 had a sensitivity of 39.5% and a specificity of 56.41% for predicting mortality.
    Conclusions: Hematological parameters have been used across the world to predict ICU mortality. PLR and NLR are simple hematological biomarkers, easy to calculate, and cost-effective, and ratios are better than individual parameters. More studies and stratified samples are required to evaluate the role of hematological markers in identifying the risk of mortality in children admitted to PICUs.
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Childhood Cancer in India: Miles to Go Before We Sleep!

    Dewan, Pooja / Jain, Prachi / Trivedi, Maharshi

    Indian pediatrics

    2023  Volume 60, Issue 12, Page(s) 1032–1034

    MeSH term(s) Humans ; Child ; Neoplasms/epidemiology ; Sleep ; India/epidemiology
    Language English
    Publishing date 2023-12-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Childhood Rashes: A Pediatrician's Dilemma.

    Dewan, Pooja / Singal, Archana

    Indian pediatrics

    2021  Volume 58, Issue 1, Page(s) 99

    MeSH term(s) Common Cold/etiology ; Exanthema ; Female ; Fever/etiology ; Humans ; Pediatricians
    Language English
    Publishing date 2021-01-15
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 859: Show issues Location:
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  8. Article ; Online: Research for Improving Patient Care.

    Dewan, Pooja / Sachdev, H P S

    Indian pediatrics

    2021  Volume 58, Issue 4, Page(s) 377–382

    Abstract: Research is an integral part of medicine. Health research aims at generating evidence for development of new medicines, procedures and tools, all of which are directed at improved patient care. Research also aims at incorporating this evidence into ... ...

    Abstract Research is an integral part of medicine. Health research aims at generating evidence for development of new medicines, procedures and tools, all of which are directed at improved patient care. Research also aims at incorporating this evidence into clinical practice by developing clinical practice guidelines and developing robust health systems including governmental policies and systems. Health research not only allows doctors to decide how to best treat patients but also empowers patients to take active role in their health.
    MeSH term(s) Humans ; Patient Care
    Language English
    Publishing date 2021-04-21
    Publishing country India
    Document type Journal Article
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 859: Show issues Location:
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  9. Article ; Online: When I speak with my eyes, I tell you more than a story.

    Dewan, Pooja / Madan, Ujjwal

    Journal of paediatrics and child health

    2021  Volume 58, Issue 6, Page(s) 1113–1114

    Language English
    Publishing date 2021-07-12
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.15646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 227: Show issues Location:
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  10. Article ; Online: Morphological markers of chromosomal instability in bone marrow aspiration and trephine biopsy of acute leukemia and myelodysplastic syndrome

    Khairwa, Anju / Kotru, Mrinalini / Dewan, Pooja / Narang, Shiva

    Environmental and Molecular Mutagenesis 2022 Dec., v. 63, no. 8-9, p. 418-422

    2022  , Page(s) 418–422

    Abstract: The role of chromosomal instability (CI) in oncogenesis is very well described in solid tumours, but there are a lack of studies on haematology malignancy, especially with multiple morphological markers. The study aims to analyze seven morphological ... ...

    Abstract The role of chromosomal instability (CI) in oncogenesis is very well described in solid tumours, but there are a lack of studies on haematology malignancy, especially with multiple morphological markers. The study aims to analyze seven morphological markers of CI‐ chromatin bridges (CB), multipolar mitosis (MPM), nuclear budding (NB), micronuclei (MN), nuclear heterogeneity (NH), laggards, chromatin strings (CS) in bone marrow aspirate (BMA) and biopsy of acute leukaemia (AL), and myelodysplastic syndrome (MDS). It is a retrospective cross‐sectional analytical study where BMA and biopsy were reviewed for CI markers. We compared CI markers in five categories. CI markers were further correlated with clinical manifestations and outcomes of patients. The study included 54 samples of 37 patients. Overall, the median (IQR) of markers were as follows: MN 3.5 (1,7), NB 5 (1,18), MPM 1 (0,4), CB 1(0,2), Laggards 0 (0,1), and CS 2.5 (0,6). NH was noted in 65.4% of samples. All CI markers except laggards were significantly increased in B‐ALL, AML, and MDS compared to other categories. Many CI markers were significantly raised with a few clinical features. The MN, MPM, Laggard, and NH markers were significantly increased in the dead patients compared to those who survived. The study, one of the first to analyze multiple CI markers, revealed that the CI markers were significantly increased in AL and MDS patients and significantly associated with clinical manifestations and outcomes. Morphology markers of CI are valuable and cost‐effective in diagnostic strategy, type of malignancies, and assessing prognosis.
    Keywords biopsy ; bone marrow ; carcinogenesis ; chromatin ; chromosomal instability ; cost effectiveness ; hematology ; leukemia ; mitosis ; mutagenesis ; prognosis
    Language English
    Dates of publication 2022-12
    Size p. 418-422
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 639145-x
    ISSN 1098-2280 ; 0893-6692
    ISSN (online) 1098-2280
    ISSN 0893-6692
    DOI 10.1002/em.22513
    Database NAL-Catalogue (AGRICOLA)

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