LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 65

Search options

  1. Article ; Online: Prosthetic joint infection diagnosis in an age of changing clinical patterns of infection and new technologies.

    Davis, Joshua S / Dewar, David / Manning, Laurens

    The Medical journal of Australia

    2024  Volume 220, Issue 5, Page(s) 225–228

    MeSH term(s) Humans ; Arthritis, Infectious ; Arthroplasty, Replacement, Knee ; Prosthesis-Related Infections/diagnosis ; Arthroplasty, Replacement, Hip ; Retrospective Studies
    Language English
    Publishing date 2024-02-13
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.52228
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Examination of Surgical Helmet and Surgical Hood Application Methods in Reducing Contamination in Arthroplasty Surgery.

    Kang, Laurant / Dewar, David / Lobo, Abhirup

    Arthroplasty today

    2021  Volume 7, Page(s) 157–160

    Abstract: Background: Contamination of the surgeon during gowning is a possible risk factor for prosthetic joint infection in arthroplasty surgery. Surgical helmets are a common form of personal protective equipment used during this type of surgery. Increasingly, ...

    Abstract Background: Contamination of the surgeon during gowning is a possible risk factor for prosthetic joint infection in arthroplasty surgery. Surgical helmets are a common form of personal protective equipment used during this type of surgery. Increasingly, there is a focus on the methods of application of the surgical hood and gown while wearing these helmets.
    Methods: Ultraviolet fluorescent powder was used to represent air-borne contaminant and applied through the airflow inlet of the surgical helmet. Seven methods of helmet and surgical gown application methods were examined. A ultraviolet torch was used to determine the level of contamination across 11 body regions. A single body region with less than 10 particles was classified as minor contamination, and over 10 particles as major contamination.
    Results: Early activation of the surgical helmet resulted in significant level of contamination across the majority of body regions. Major contamination also affected the scrub nurse when applying the surgical hood to the surgeon's helmet. Late activation of helmet system resulted in only minor level of contamination to the surgeon's shoulders and forearms. Adhesive wrist wraps over the inner gloves did not decrease contamination when added to late activation of the helmet.
    Conclusion: It is our recommendation that the surgical hood should be applied by an unsterile theater assistant and that the surgical helmet system should be activated after the surgeon has applied inner gloves to minimize the level of contamination to the surgeon's gown.
    Language English
    Publishing date 2021-01-30
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2020.11.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Clinician-driven research priorities in bone and joint infection: perspectives of orthopaedic surgeons and infectious diseases physicians.

    Davis, Joshua S / Kang, Laurant Xi / Manning, Laurens / Dewar, David

    ANZ journal of surgery

    2022  Volume 92, Issue 11, Page(s) 2790–2792

    MeSH term(s) Humans ; Orthopedic Surgeons ; Specialization ; Physicians ; Research ; Arthritis, Infectious ; Communicable Diseases
    Language English
    Publishing date 2022-10-29
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.18052
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Postinjury multiple organ failure in polytrauma: more frequent and potentially less deadly with less crystalloid.

    King, Kate L / Dewar, David C / Briggs, Gabrielle D / Jones, Mark / Balogh, Zsolt J

    European journal of trauma and emergency surgery : official publication of the European Trauma Society

    2023  Volume 50, Issue 1, Page(s) 131–138

    Abstract: Background: Recently, retrospective registry-based studies have reported the decreasing incidence and increasing mortality of postinjury multiple organ failure (MOF). We aimed to describe the current epidemiology of MOF following the introduction of ... ...

    Abstract Background: Recently, retrospective registry-based studies have reported the decreasing incidence and increasing mortality of postinjury multiple organ failure (MOF). We aimed to describe the current epidemiology of MOF following the introduction of haemostatic resuscitation.
    Methods: A 10-year prospective cohort study was undertaken at a Level-1 Trauma Centre-based ending in December 2015. Inclusion criteria age ≥ 16 years, Injury Severity Score (ISS) > 15, Abbreviated Injury Scale (AIS) Head < 3 and survived > 48 h. Demographics, physiological and shock resuscitation parameters were collected. The primary outcome was MOF defined by a Denver Score > 3.
    Secondary outcomes: intensive care unit length of stay (ICU LOS), ventilation days and mortality.
    Results: Three hundred and forty-seven patients met inclusion criteria (age 48 ± 20; ISS 30 ± 11, 248 (71%) were males and 23 (6.6%) patients died. The 74 (21%) MOF patients (maximum Denver Score: 5.5 ± 1.8; Duration; 5.6 ± 5.8 days) had higher ISS (32 ± 11 versus 29 ± 11) and were older (54 ± 19 versus 46 ± 20 years) than non-MOF patients. Mean daily Denver scores adjusted for age, sex, MOF and ISS did not change over time. Crystalloid usage decreased over the 10-year period (p value < 0.01) and PRBC increased (p value < 0.01). Baseline cumulative incidence of MOF at 28 days was 9% and competing risk analyses showed that incidence of MOF increased over time (subdistribution hazard ratio 1.14, 95% CI 1.04 to 1.23, p value < 0.01). Mortality risk showed no temporal change. ICU LOS increased over time (subdistribution hazard ratio 0.95, 95% CI 0.92 to 0.98, p value < 0.01). Ventilator days increased over time (subdistribution hazard ratio 0.94, 95% CI 0.9 to 0.97, p value < 0.01).
    Conclusion: The epidemiology of MOF continues to evolve. Our prospective cohort suggests an ageing population with increasing incidence of MOF, particularly in males, with little changes in injury or shock parameters, who are being resuscitated with less crystalloids, stay longer on ICU without improvement in survival.
    MeSH term(s) Male ; Humans ; Adolescent ; Adult ; Middle Aged ; Aged ; Female ; Prospective Studies ; Retrospective Studies ; Multiple Organ Failure ; Crystalloid Solutions ; Multiple Trauma/epidemiology ; Injury Severity Score
    Chemical Substances Crystalloid Solutions
    Language English
    Publishing date 2023-01-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2275480-5
    ISSN 1863-9941 ; 1863-9933
    ISSN (online) 1863-9941
    ISSN 1863-9933
    DOI 10.1007/s00068-022-02202-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Book ; Online: Urban Markets

    Dewar, David / Watson, Vanessa

    Developing Informal Retailing

    (Routledge Library Editions: Urban Planning Ser ; v.8)

    2018  

    Abstract: Cover page -- Halftitle page -- Title page -- Copyright page -- Title page -- Copyright page -- Contents -- List of plates -- List of figures -- Preface -- Chapter 1 Introduction: Urban markets and informal-sector stimulation -- Chapter 2 Urban markets: ... ...

    Series title Routledge Library Editions: Urban Planning Ser ; v.8
    Abstract Cover page -- Halftitle page -- Title page -- Copyright page -- Title page -- Copyright page -- Contents -- List of plates -- List of figures -- Preface -- Chapter 1 Introduction: Urban markets and informal-sector stimulation -- Chapter 2 Urban markets: some issues relating to their location, design and administration -- Chapter 3 The empirical foundation -- Chapter 4 Market cases -- Bibliography -- Index
    Language English
    Size 1 Online-Ressource (171 pages)
    Document type Book ; Online
    ISBN 9781138485310 ; 9781351049863 ; 9781138485310 ; 1138485314 ; 1351049860 ; 1138485314
    Database ECONomics Information System

    More links

    Kategorien

  6. Article ; Online: Individuals with musculoskeletal conditions awaiting orthopaedic surgery consultation: an untapped opportunity for patient health management?

    Davidson, Simon Re / Robson, Emma / O'Brien, Kate M / Kamper, Steven J / Haskins, Robin / Ajitsaria, Pragya / Dewar, David / Williams, Christopher M

    Public health research & practice

    2023  

    Abstract: Objective: To describe the health characteristics, condition-specific measures, chronic disease risk factors, and healthcare and medication use over time of individuals with musculoskeletal conditions awaiting orthopaedic surgical consultation. Study ... ...

    Abstract Objective: To describe the health characteristics, condition-specific measures, chronic disease risk factors, and healthcare and medication use over time of individuals with musculoskeletal conditions awaiting orthopaedic surgical consultation. Study importance: Musculoskeletal conditions are highly prevalent in the general population and often coexist with chronic diseases. However, little is documented about the overall health of this group. This study describes the health of these individuals, with particular emphasis on modifiable risk factors of chronic disease.
    Study type: A repeated measures longitudinal cohort study of individuals referred for orthopaedic consultation across three time points (2014, 2015 and 2016).
    Methods: This study was undertaken in the orthopaedic outpatient service of a public tertiary referral hospital in New South Wales, Australia. Participants were aged 18 years and older and were referred for and awaiting orthopaedic surgical consultation for a musculoskeletal condition (back, neck, hand or wrist pain, or hip or knee osteoarthritis). Measures included patient demographics, condition-specific indicators (e.g. pain, disability, quality of life [QoL]) and chronic disease risk factors (e.g., excess weight, smoking).
    Results: The mean age of participants was 57.7 years, and 7.3% identified as Aboriginal and/or Torres Strait Islander. Back (43.1%) and knee (35.0%) pain were the most prevalent conditions. At baseline (N = 1052), participants reported moderate pain (mean numerical pain rating scale score of 6.4, standard deviation [SD] 2.4) and QoL (Physical Component Score of 32.7, SD 10.7; Mental Component Score of 46.6, SD 13.3). Chronic disease risk factors were highly prevalent, with 74.6% of participants having three or more. For most measures, there were only small changes over time.
    Conclusion: Individuals with musculoskeletal conditions who are awaiting orthopaedic surgical consultation have a complex clinical picture and numerous chronic disease risk factors. Given the modifiable nature of many of these risk factors, identifying and addressing them before or while awaiting consultation may improve the health of these individuals.
    Language English
    Publishing date 2023-12-14
    Publishing country Australia
    Document type Journal Article
    ISSN 2204-2091
    ISSN (online) 2204-2091
    DOI 10.17061/phrp33452312
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Prediction of survival after surgical management of femoral metastatic bone disease - A comparison of prognostic models.

    Meares, Charles / Badran, Alexander / Dewar, David

    Journal of bone oncology

    2019  Volume 15, Page(s) 100225

    Abstract: Background: Operative fixation for femoral metastatic bone disease is based on the principles of reducing pain and restoring function. Recent literature has proposed a number of prognostic models for appendicular metastatic bone disease. The aim of this ...

    Abstract Background: Operative fixation for femoral metastatic bone disease is based on the principles of reducing pain and restoring function. Recent literature has proposed a number of prognostic models for appendicular metastatic bone disease. The aim of this study was to compare the accuracy of proposed soring systems in the setting of femoral metastatic bone disease in order to provide surgeons with information to determine the most appropriate scoring system in this setting.
    Methods: A retrospective cohort analysis of patients who underwent surgical management of femoral metastatic bone disease at a single institution were included. A pre-operative predicted survival for all 114 patients was retrospectively calculated utilising the revised Katagiri model, PathFx model, SSG score, Janssen nomogram, OPTModel and SPRING 13 nomogram. Univariate and multivariate Cox regression proportional hazard models were constructed to assess the role of prognostic variables in the patient group. Area under the receiver characteristics and Brier scores were calculated for each prognostic model from comparison of predicted survival and actual survival of patients to quantify the accuracy of each model.
    Results: For the femoral metastatic bone disease patients treated with surgical fixation, multivariate analysis demonstrated a number of pre-operative factors associated with survival in femoral metastatic bone disease, consistent with established literature. The OPTIModel demonstrated the highest accuracy at predicting 12-month (Area Under the Curve [AUC] = 0.79) and 24-month (AUC = 0.77) survival after surgical management. PathFx model was the most accurate at predicting 3-month survival (AUC = 0.70) and 6-month (AUC = 0.70) survival. The PathFx model was successfully externally validated in the femoral patient dataset for all time periods.
    Conclusions: Among six prognostic models assessed in the setting of femoral metastatic bone disease, the present study observed the most accurate model for 3-month, 6-month, 12-month and 24-month survival. The results of this study may be utilised by the treating surgical team to determine the most accurate model for the required time period and therefore improve decision-making in the care of patients with femoral metastatic bone disease.
    Language English
    Publishing date 2019-02-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2212-1366
    ISSN 2212-1366
    DOI 10.1016/j.jbo.2019.100225
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Book: A history of British national audit

    Dewar, David / Funnell, Warwick

    the pursuit of accountability

    2017  

    Abstract: The core theme of the book is the importance of an independent state audit to ensure that the Executive is held accountable to Parliament. Instilling effective financial control and accountability for the use of public funds and the proper conduct of ... ...

    Author's details David Dewar; Warwick Funnell
    Abstract The core theme of the book is the importance of an independent state audit to ensure that the Executive is held accountable to Parliament. Instilling effective financial control and accountability for the use of public funds and the proper conduct of public business has been an incremental process that has taken centuries. This book provides a detailed history of the forces and personalities involved in the development of public sector audit, including the battles which extended well into the 20th century to establish a public sector audit that was constitutionally and in practice independent from the influence and control of the Executive. It identifies key themes that have emerged and re-emerged in these developments, and the challenges and obstacles faced and overcome over the years to arrive at today's modern audit framework and to establish current principles and practice in accountability to Parliament and the public.0The book charts the movement of public sector audit from a focus on the presentation and accuracy of accounts to the introduction of the added dimension of ensuring that funds are spent only for purposes approved by Parliament and that resources have been used efficiently, effectively and with economy. It explores the seminal relationships of the NAO and its predecessors with the Treasury, spending departments and the Public Accounts Committee; and it deals with the impact of major changes still taking place in the objectives, management and delivery of government programmes and services, including the growing involvement of outside agencies and the private sector. The book reviews the NAO's current achievements, continuing challenges, developments in the range and nature of its work, and future priorities. Importantly, it provides an authoritative source of reference for professionals and academics, while remaining accessible to readers with a more general interest in the developments and issues examined
    Keywords Öffentliches Rechnungswesen ; Wirtschaftsprüfung ; Geschichte ; Großbritannien
    Language English
    Size viii, 303 Seiten
    Publisher Oxford University Press
    Publishing place Oxford
    Document type Book
    ISBN 0198790317 ; 9780198790310
    Database ECONomics Information System

    More links

    Kategorien

  9. Article ; Online: Open Debridement is Superior to Arthroscopic Debridement for the Infected Total Knee Arthroplasty.

    Johns, Brenton P / Loewenthal, Mark R / Davis, Joshua S / Dewar, David C

    The Journal of arthroplasty

    2020  Volume 35, Issue 12, Page(s) 3716–3723

    Abstract: Background: Acutely infected total knee arthroplasty (TKA) is commonly treated with debridement, antibiotics, and implant retention (DAIR). There are no direct comparative studies to determine whether debridement should be performed open or ... ...

    Abstract Background: Acutely infected total knee arthroplasty (TKA) is commonly treated with debridement, antibiotics, and implant retention (DAIR). There are no direct comparative studies to determine whether debridement should be performed open or arthroscopically for infected TKA. The aim of this study is to compare the outcomes of open vs arthroscopic debridement of infected TKAs.
    Methods: All patients at a university teaching hospital with an infected TKA treated with DAIR between 2002 and 2017 were analyzed. The primary outcome was successful treatment defined using international consensus criteria. Secondary outcomes included antibiotic suppression, prosthesis retention, mortality, postoperative range of motion, and length of stay. Clinical, laboratory, surgical, and antibiotic treatment data were collected. Propensity score matching was performed to control for selection bias.
    Results: DAIR was used in 141 patients. The initial DAIR procedure was open for 96 patients and arthroscopic for 45 patients. The success rate was 29% greater for open DAIR (45% open vs 16% arthroscopic; P < .001). After propensity score matching, this benefit was estimated to be 36% (95% confidence interval, 22%-50%; P < .0001). When those on antibiotic suppression were also considered successfully treated, open DAIR was still superior by 34% (95% confidence interval, 18%-51%; P < .0001).
    Conclusion: For infected TKA, open DAIR is a more successful index procedure compared with arthroscopic DAIR. Open DAIR remained more successful even when antibiotic suppression is considered successful treatment.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Arthroplasty, Replacement, Knee/adverse effects ; Debridement ; Humans ; Prosthesis-Related Infections/drug therapy ; Prosthesis-Related Infections/surgery ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-06-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632770-9
    ISSN 1532-8406 ; 0883-5403
    ISSN (online) 1532-8406
    ISSN 0883-5403
    DOI 10.1016/j.arth.2020.06.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Book: Regional development and settlement policy

    Dewar, David / Todes, Alison / Watson, Vanessa

    premises and prospects

    (Routledge library editions : Urban and regional economics ; volume 4)

    2018  

    Author's details David Dewar, Alison Todes, Vanessa Watson
    Series title Routledge library editions : Urban and regional economics ; volume 4
    Keywords Raumordnung ; Entwicklungsplanung ; Siedlung ; Regionalentwicklung
    Language English
    Dates of publication 2018-1986
    Size x, 175 Seiten
    Document type Book
    Note "First published in 1986 by Allen & Unwin" - Rückseite der Titelseite
    ISBN 9781138101944 ; 9781315103273 ; 113810194X ; 1315103273
    Database ECONomics Information System

    More links

    Kategorien

To top