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  1. Article ; Online: Prevalence and treatment of retrograde peri-implantitis: a retrospective cohort study covering a 20-year period.

    Di Murro, Bianca / Canullo, Luigi / Pompa, Giorgio / Di Murro, Carlo / Papi, Piero

    Clinical oral investigations

    2021  Volume 25, Issue 7, Page(s) 4553–4561

    Abstract: Objectives: The aims of this retrospective study were to report data on the prevalence of retrograde peri-implantitis (RPI) in a single-center in a 20-year observation period and to evaluate implant survival after surgical treatment.: Materials and ... ...

    Abstract Objectives: The aims of this retrospective study were to report data on the prevalence of retrograde peri-implantitis (RPI) in a single-center in a 20-year observation period and to evaluate implant survival after surgical treatment.
    Materials and methods: A retrospective cohort study was conducted screening all patients who underwent implant treatment in a private practice. Patients were enrolled if they had one or more implants showing a radiolucency around the implant apex, without implant mobility. Furthermore, clinical symptoms of RPI and days from symptoms' appearance after implant placement were also collected, as well as periodontal and endodontic status of nearby teeth. All patients were treated with the same surgical approach: antibiotic therapy, mechanical curettage, chemical decontamination and xenograft application.
    Results: Out of the 1749 implants placed, only 6 implants were classified as affected by RPI, with a prevalence of 0.34%. Clinical symptoms of RPI (pain, swelling, dull percussion or fistula presence) varied among patients and were reported after a mean period of 51.83 ± 52.43 days.
    Conclusions: RPI was successfully treated with surgical curettage and bone substitute application and all implants are still in place after a mean follow-up of 8.83 ± 5.34 years.
    Clinical relevance: Bacteria from teeth with failed endodontic treatment or residual lesions might be reactivated by drilling for implant osteotomy, with subsequent colonization of the implant apex and possible failure before prosthetic loading. Therefore, it might be recommended to take a periapical x-ray at implant placement and after 6-8 weeks in order to intercept RPI before prostheses delivery.
    MeSH term(s) Dental Implantation, Endosseous ; Dental Implants ; Humans ; Peri-Implantitis/diagnostic imaging ; Peri-Implantitis/epidemiology ; Peri-Implantitis/therapy ; Prevalence ; Retrospective Studies
    Chemical Substances Dental Implants
    Language English
    Publishing date 2021-01-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-020-03769-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Correlation between endodontic pulpal/periapical disease and retrograde peri-implantitis: A case series.

    Di Murro, Bianca / Papi, Piero / Di Murro, Carlo / Pompa, Giorgio / Gambarini, Gianluca

    Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

    2020  Volume 47, Issue 2, Page(s) 358–364

    Abstract: Retrograde peri-implantitis is a symptomatic complication, characterised by radiographic detection of bone loss at the periapex of the implant. The aim of this study was to investigate the possible endodontic aetiology, evaluating the effectiveness of ... ...

    Abstract Retrograde peri-implantitis is a symptomatic complication, characterised by radiographic detection of bone loss at the periapex of the implant. The aim of this study was to investigate the possible endodontic aetiology, evaluating the effectiveness of surgical treatment without endodontic therapy of adjacent teeth. In the 10-year interval, three patients reported symptoms of retrograde peri-implantitis after a mean period of 30.6 days from implant placement. Mean follow-up after surgical procedures was 8.66 years, with an implant survival of 100%. Retrograde peri-implantitis was probably caused by colonisation of the apical surface of the implant by bacteria persisting in the area after endodontic failure/apical periodontitis, reactivated by drilling in the site. In all cases, the adjacent teeth remained vital during the years, showing that a direct cause-and-effect relationship between pulpal/periapical disease of adjacent teeth and retrograde peri-implantitis was never present.
    MeSH term(s) Dental Implants ; Dental Pulp ; Dental Pulp Diseases ; Humans ; Peri-Implantitis/diagnostic imaging ; Peri-Implantitis/etiology ; Periapical Periodontitis/diagnostic imaging ; Periapical Periodontitis/surgery
    Chemical Substances Dental Implants
    Language English
    Publishing date 2020-11-07
    Publishing country Australia
    Document type Case Reports
    ZDB-ID 2146484-4
    ISSN 1747-4477 ; 1329-1947
    ISSN (online) 1747-4477
    ISSN 1329-1947
    DOI 10.1111/aej.12458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Could early rheumatoid arthritis resolve after periodontitis treatment only?: case report and review of the literature.

    Salemi, Simonetta / Biondo, Michela I / Fiorentino, Chiara / Argento, Giuseppe / Paolantonio, Michele / Di Murro, Carlo / Malagnino, Vito A / Canzoni, Marco / Diamanti, Andrea Picchianti / D'Amelio, Raffaele

    Medicine

    2014  Volume 93, Issue 27, Page(s) e195

    Abstract: Rheumatoid arthritis (RA) is an immune-mediated polyarthritis; currently no pathogenic agent has been identified as a disease trigger. A patient with RA, presumably caused by periodontal infection, whose remission has been observed after periodontitis ... ...

    Abstract Rheumatoid arthritis (RA) is an immune-mediated polyarthritis; currently no pathogenic agent has been identified as a disease trigger. A patient with RA, presumably caused by periodontal infection, whose remission has been observed after periodontitis treatment in absence of specific RA therapy, is reported here for the first time, to our knowledge. A 61-year-old male patient presented migrant arthritis associated with antibodies against citrullinated protein antigens positivity. The clinical features allowed to make RA diagnosis according to the 2010 European League against Rheumatism/American College of Rheumatology RA classification criteria. X-ray of the second upper molar showed chronic apical periodontitis. After its treatment, arthritis remission has been observed in the absence of specific RA therapy. It has been suggested that periodontitis may have a trigger role in RA pathogenesis. This could be explained by the enzymatic action of Porphyromonas gingivalis, probably leading to break tolerance to collagen. The identification and subsequent treatment of periodontitis should therefore be considered pivotal in RA prophylaxis and management.
    MeSH term(s) Arthritis, Rheumatoid/etiology ; Arthritis, Rheumatoid/therapy ; Humans ; Male ; Middle Aged ; Periodontitis/complications ; Periodontitis/therapy
    Language English
    Publishing date 2014-12-11
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000000195
    Database MEDical Literature Analysis and Retrieval System OnLINE

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