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Article: Utility of native T1 mapping and myocardial extracellular volume fraction in patients with nonischemic dilated cardiomyopathy: A systematic review and meta-analysis.

Tao, Michael / Dhaliwal, Simrat / Ghosalkar, Dhairyasheel / Sheng, Siyuan / Dianati-Maleki, Neda / Tam, Edlira / Rahman, Tahmid / Mann, Noelle / Kort, Smadar

International journal of cardiology. Heart & vasculature

2024 Volume 51, Page(s) 101339

Abstract: Background: Cardiac magnetic resonance imaging (CMR) based T1 mapping and extracellular volume fraction (ECV) are powerful tools for identifying myocardial fibrosis. This systematic review and : Methods: A literature search was conducted for studies ... ...

Abstract	Background: Cardiac magnetic resonance imaging (CMR) based T1 mapping and extracellular volume fraction (ECV) are powerful tools for identifying myocardial fibrosis. This systematic review and Methods: A literature search was conducted for studies reporting on use of CMR-based native T1 mapping and ECV measurement in NICM patients and their association with major adverse cardiac events (MACE), ventricular arrhythmias (VAs), and left ventricular reverse remodeling (LVRR). Databases searched included: Ovid MEDLINE, EMBASE, Web of Science, and Google Scholar. The search was not restricted to time or publication status. Results: Native T1 and ECV were significantly higher in NICM patients compared to controls (MD 78.80, 95 % CI 50.00, 107.59; p < 0.01; MD 5.86, 95 % CI 4.55, 7.16; p < 0.01). NICM patients who experienced MACE had higher native T1 and ECV (MD 52.87, 95 % CI 26.59, 79.15; p < 0.01; MD 6.03, 95 % CI 3.79, 8.26; p < 0.01). There was a non-statistically significant trend toward higher native T1 time in NICM patients who experienced VAs. NICM patients who were poor treatment responders had higher baseline native T1 and ECV (MD 40.58, 95 % CI 12.90, 68.25; p < 0.01; MD 3.29, 95 % CI 2.25, 4.33; p < 0.01). Conclusions: CMR-based native T1 and ECV quantification may be useful tools for risk stratification of patients with NICM. They may provide additional diagnostic utility in combination with LGE, which poorly characterizes fibrosis in patients with diffuse myocardial involvement.
Language	English
Publishing date	2024-02-09
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	2818464-6
ISSN	2352-9067
ISSN	2352-9067
DOI	10.1016/j.ijcha.2024.101339
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Article ; Online: The Use of Quality Improvement Interventions in Reducing Rarely Appropriate Cardiac Imaging.

Al-Sadawi, Mohammed / Tao, Michael / Frye, Jesse / Dianati-Maleki, Neda / Mann, Noelle

The American journal of cardiology

2023 Volume 207, Page(s) 349–355

Abstract: The use of cardiac imaging has become increasingly prevalent over the last decade. Approximately 10% to 15% of noninvasive cardiac imaging is ordered for rarely appropriate indications. The appropriate use criteria (AUC) for cardiac imaging were issued ... ...

Abstract	The use of cardiac imaging has become increasingly prevalent over the last decade. Approximately 10% to 15% of noninvasive cardiac imaging is ordered for rarely appropriate indications. The appropriate use criteria (AUC) for cardiac imaging were issued to decrease unnecessary testing and reduce health care costs. However, it remains unclear whether these efforts have been successful. This meta-analysis evaluates whether AUC quality improvement (QI) interventions effectively reduce inappropriate cardiac imaging. Databases were searched for studies reporting QI intervention effect aiming to reduce rarely appropriate noninvasive cardiac imaging based on AUC. Imaging modalities assessed include transthoracic echocardiography, stress echocardiography, and myocardial perfusion imaging. We searched Ovid MEDLINE, EMBASE, Scopus, Web of Science, Google Scholar, and EBSCO CINAHL. The primary end point was a decrease of rarely appropriate testing. The search was not restricted to time or publication status. The literature search identified 2,391 possible studies, 13 studies and 26,557 patients were included. Mean follow-up was 12 months (1 to 60 months). QI interventions were statistically significant in reducing rarely appropriate tests after the intervention compared with the control group (odds ratio [OR] 0.51, 95% confidence interval [CI] 0.41 to 0.64, p <0.01). The QI interventions were also assessed for persistence based on short-term (<3 months) and long-term (>3 months) efficacy. Both the short-term effect and long-term effect were persistent (OR 0.6, 95% CI 0.47 to 0.77, p <0.01 and OR 0.47, 95% CI 0.37 to 0.61, p <0.01, respectively). AUC QI interventions are associated with the successful decrease of inappropriate noninvasive cardiac testing with these effects persisting over time.
MeSH term(s)	Humans ; Quality Improvement ; Health Care Costs ; Echocardiography ; Myocardial Perfusion Imaging
Language	English
Publishing date	2023-09-27
Publishing country	United States
Document type	Meta-Analysis ; Journal Article ; Review
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.08.188
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Article ; Online: The use of quality improvement interventions in reducing rarely appropriate echocardiograms: A systematic review and meta-analysis.

Tao, Michael / Al-Sadawi, Mohammed / Ahmed, Navid / Dianati-Maleki, Neda / Mann, Noelle / Kort, Smadar

Echocardiography (Mount Kisco, N.Y.)

2023 Volume 40, Issue 9, Page(s) 916–924

Abstract: Background: The volume of cardiac imaging continues to increase, with many tests performed for rarely appropriate indications. Appropriate use criteria (AUC) documents were published by the American Society of Echocardiography and American College of ... ...

Abstract	Background: The volume of cardiac imaging continues to increase, with many tests performed for rarely appropriate indications. Appropriate use criteria (AUC) documents were published by the American Society of Echocardiography and American College of Cardiology, with quality improvement (QI) interventions developed in various institutions. However, the effectiveness of these interventions has not been assessed in a systematic fashion. Methods: We searched Ovid MEDLINE, EMBASE, Scopus, Web of Science, Google Scholar, and EBSCO CINAHL for studies reporting association between cardiac imaging, AUC and QI. The search was not restricted to time or publication status. We selected studies assessing the effect of QI interventions on performance of rarely appropriate echocardiograms. The primary endpoint was reduction of rarely appropriate testing. Results: Nine studies with 22,070 patients met inclusion criteria. Mean follow up was 15 months (1-60 months). QI interventions resulted in statistically significant reduction in rarely appropriate tests (OR 0.52, 95% CI: .41-.66; p < .01). The effects of QI interventions were analyzed over both the short (<3 months) and long-term (>3 months) post intervention (OR 0.62, 95% CI: .49-.79; p < .01 in the short term, and OR 0.47, 95% CI: .35-.62; p < .01 in the long term). Subgroup analysis of the type of intervention, classified as education tools or decision support tools showed both significantly reduced rarely appropriate testing (OR 0.54, 95% CI: .41-.73; p < .01; OR .47, 95% CI: .36-.61; p < .01). Adding a feedback tool did not change the effect compared to not using a feedback tool (OR 0.49 vs. 0.57, 95% CI: .36-.68 vs. 39-.84; p > .05). Conclusion: QI interventions are associated with a significant reduction in performance of rarely appropriate echocardiography testing, the effects of which persist over time. Both education and decision support tools were effective, while adding feedback tools did not result in further reduction of ordering rarely appropriate studies.
MeSH term(s)	Humans ; United States ; Quality Improvement ; Echocardiography
Language	English
Publishing date	2023-07-19
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	843645-9
ISSN	1540-8175 ; 0742-2822
ISSN (online)	1540-8175
ISSN	0742-2822
DOI	10.1111/echo.15653
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Zs.A 2170: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Diabetes Mellitus in Patients With Heart Failure: Bad for All, Worse for Some.

Dianati-Maleki, Neda / Butler, Javed

JACC. Heart failure

2016 Volume 5, Issue 1, Page(s) 25–27

MeSH term(s)	Diabetes Mellitus ; Heart Failure ; Humans ; Stroke Volume
Language	English
Publishing date	2016-12-27
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2705621-1
ISSN	2213-1787 ; 2213-1779
ISSN (online)	2213-1787
ISSN	2213-1779
DOI	10.1016/j.jchf.2016.11.002
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Article: Management of Saphenous Vein Graft Disease in Patients with Prior Coronary Artery Bypass Surgery.

Dianati Maleki, Neda / Ehteshami Afshar, Arash / Parikh, Puja B

Current treatment options in cardiovascular medicine

2019 Volume 21, Issue 2, Page(s) 12

Abstract: Purpose of review: In this review, we summarize the pathogenesis of saphenous venous graft (SVG) failure in patients following coronary artery bypass graft (CABG) surgery. We also provide an update on various aspects of prevention and management of SVG ... ...

Abstract	Purpose of review: In this review, we summarize the pathogenesis of saphenous venous graft (SVG) failure in patients following coronary artery bypass graft (CABG) surgery. We also provide an update on various aspects of prevention and management of SVG failure. Recent findings: Application of perioperative measures and medical therapies to promote SVG patency is crucial to optimize clinical outcomes in patients following CABG. Percutaneous coronary intervention (PCI) of SVG disease is fraught with complications, with the highest risk being no-reflow and periprocedural myocardial infarction due to distal embolization of microemboli. Minimizing this risk with use of distal embolic protection when feasible and understanding the role of adjunctive pharmacotherapies is critical in reducing the risk of adverse cardiac events. The long-term patency of SVGs remains a contemporary challenge and is adversely affected by thrombotic occlusion, intimal fibrosis, and accelerated atherosclerosis. Prevention of SVG failure is multifactorial. Use of perioperative measures, medical therapies, and PCI techniques to promote SVG patency is vital to optimize outcomes in patients following CABG. Further prospective trials are needed to define the optimal medical and surgical therapy to maintain short- and long term SVG patency.
Language	English
Publishing date	2019-02-28
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2057337-6
ISSN	1534-3189 ; 1092-8464
ISSN (online)	1534-3189
ISSN	1092-8464
DOI	10.1007/s11936-019-0714-7
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Article ; Online: Outcomes and Medical Therapy in Myocardial Infarction With Nonobstructive Coronary Arteries: A Systematic Review and Meta-Analysis.

Tao, Michael / Al-Sadawi, Mohammed / Dhaliwal, Simrat / Gier, Chad / Masson, Ravi / Miller, Alec / Price, Jordan / Dianati-Maleki, Neda / Rahman, Tahmid / Bench, Travis / Mann, Noelle

The American journal of cardiology

2023 Volume 207, Page(s) 456–464

Abstract: Myocardial infarction with nonobstructive coronary arteries (MINOCAs) is a disease that has been poorly characterized with unclear clinical and therapeutic outcomes. The association of medical therapy with cardiovascular outcomes in patients with MINOCA ... ...

Abstract	Myocardial infarction with nonobstructive coronary arteries (MINOCAs) is a disease that has been poorly characterized with unclear clinical and therapeutic outcomes. The association of medical therapy with cardiovascular outcomes in patients with MINOCA has been inadequately assessed. The purpose of this meta-analysis is to evaluate the association of MINOCA at risk of adverse cardiovascular outcomes as compared with myocardial infarction with coronary artery disease (MICAD) and the efficacy of medical therapy in reducing the risk of adverse outcomes. A literature search was conducted for studies reporting on the association of MINOCA at risk of adverse outcomes as compared with MICAD. A literature search was also conducted for studies reporting on the association of medical therapy at risk of adverse outcomes in patients with MINOCA. A total of 29 studies with 893,134 participants met inclusion criteria comparing MINOCA to MICAD. Patients with MINOCA had a significantly lower risk of adverse outcomes as compared with MICAD. Nine studies with 27,731 MINOCA patients met inclusion criteria for evaluating the utility of medical therapy. Medical therapy did not significantly reduce risk of MACE; however, there was a trend toward lower risk in patients treated with β blockers. In conclusion, our results suggest that MINOCA is associated with a lower risk of in-hospital and long-term adverse outcomes compared with MICAD. Standard medical therapy is not associated with a lower risk of adverse cardiovascular outcomes in patients with MINOCA. Additional high-quality studies are required to evaluate the utility of specific medication classes for the treatment of specific etiologies of MINOCA.
MeSH term(s)	Humans ; MINOCA ; Coronary Angiography/adverse effects ; Myocardial Infarction/drug therapy ; Myocardial Infarction/epidemiology ; Myocardial Infarction/etiology ; Coronary Artery Disease/complications ; Coronary Artery Disease/drug therapy ; Coronary Vessels/diagnostic imaging ; Risk Factors ; Prognosis
Language	English
Publishing date	2023-10-05
Publishing country	United States
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.08.189
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Article ; Online: Postpartum Cardiovascular Outcomes Among Women With Heart Disease from A Nationwide Study.

Lima, Fabio / Nie, Lizhou / Yang, Jie / Owens, Amanda / Dianati-Maleki, Neda / Avila, Cecilia / Stergiopoulos, Kathleen

The American journal of cardiology

2019 Volume 123, Issue 12, Page(s) 2006–2014

Abstract: There is limited data on postpartum maternal postpartum major adverse cardiovascular and cerebrovascular events (MACCE) among women with heart disease (HD) in the US. Therefore, we aimed to determine the prevalence and predictors of MACCE in the US. The ... ...

Abstract	There is limited data on postpartum maternal postpartum major adverse cardiovascular and cerebrovascular events (MACCE) among women with heart disease (HD) in the US. Therefore, we aimed to determine the prevalence and predictors of MACCE in the US. The Nationwide Readmissions Databases (2010 to 2014) were screened for patients with and without HD undergoing delivery. HD subtypes included cardiomyopathy (CDM), congenital heart disease, valvular heart disease, and pulmonary hypertension. Rates and reasons of 42-day readmission were determined using weighted national estimates. Independent predictors of postpartum MACCE were determined using multivariable logistic regression for complex survey data. We found among 15,273,247 patients hospitalized for delivery, 33,827 had HD (CDM 22.78%, congenital heart disease 45.98%, valvular heart disease 24.81%, and pulmonary hypertension 6.41%). Of these, 5.2% of HD patients and 1.4% of No HD were readmitted. MACCE was higher in HD vs No HD (2.68% vs 0.17%, p <0.0001). Median time to MACCE was 5.6 days (interquartile range 3 to 15 days). CDM had >10% readmission at 42 days. Among HD patients, cardiovascular, infectious, hypertensive syndromes, and complications of pregnancy were the most common reasons for 42-day readmission. MACCE predictors in women with HD included HD subtype, age, insurance status, obesity, eclampsia, postpartum hemorrhage, MACCE during delivery, preterm delivery, and thrombotic complications. In conclusion, among a nationwide analysis, postpartum MACCE was more common among patients with HD especially within 1 week of discharge from delivery. Predictors can be easily screened for by clinicians, including presence of any HD, hypertensive syndromes, age, obesity, and obstetrical events during index hospitalization.
MeSH term(s)	Adult ; Cardiomyopathies/epidemiology ; Databases, Factual ; Female ; Hospitalization ; Humans ; Logistic Models ; Pregnancy ; Pregnancy Complications, Cardiovascular/epidemiology ; Prevalence ; Puerperal Disorders/epidemiology ; Retrospective Studies ; United States/epidemiology ; Young Adult
Language	English
Publishing date	2019-03-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2019.03.012
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Article ; Online: Use of electrocardiogram indices of myocardial ischemia for risk stratification and decision making of reperfusion strategies.

Dianati Maleki, Neda / Ehteshami Afshar, Arash / Armstrong, Paul W

Journal of electrocardiology

2014 Volume 47, Issue 4, Page(s) 520–524

Abstract: After about a century since its clinical introduction, the 12-lead electrocardiogram (ECG) remains a cornerstone in diagnosis and management of acute ST-elevation myocardial infarction (STEMI). It provides clinicians and researchers with invaluable ... ...

Abstract	After about a century since its clinical introduction, the 12-lead electrocardiogram (ECG) remains a cornerstone in diagnosis and management of acute ST-elevation myocardial infarction (STEMI). It provides clinicians and researchers with invaluable information regarding the presence, location, and extent of myocardial infarction. Moreover the ECG contains a wealth of prognostic information useful in risk stratification of STEMI patients and identification of particular subgroups that may benefit from more aggressive therapeutic interventions. New data suggest the ECG may be useful in guiding the choice of reperfusion treatment when primary percutaneous coronary intervention (PCI) cannot be delivered in the timeframe recommended by current STEMI guidelines. This paper summarizes the role of the ECG in assessing the baseline risk of patients with STEMI and evaluates the use of ECG indices in decision making of reperfusion strategies.
MeSH term(s)	Decision Support Techniques ; Diagnosis, Computer-Assisted/methods ; Electrocardiography/methods ; Evidence-Based Medicine ; Humans ; Myocardial Ischemia/diagnosis ; Myocardial Ischemia/surgery ; Myocardial Reperfusion/methods ; Patient Selection ; Reproducibility of Results ; Risk Assessment ; Sensitivity and Specificity ; Severity of Illness Index
Language	English
Publishing date	2014-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	410286-1
ISSN	1532-8430 ; 0022-0736
ISSN (online)	1532-8430
ISSN	0022-0736
DOI	10.1016/j.jelectrocard.2014.04.006
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Article ; Online: Effect of telemedicine on glycated hemoglobin in diabetes: a systematic review and meta-analysis of randomized trials.

Faruque, Labib Imran / Wiebe, Natasha / Ehteshami-Afshar, Arash / Liu, Yuanchen / Dianati-Maleki, Neda / Hemmelgarn, Brenda R / Manns, Braden J / Tonelli, Marcello

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

2016 Volume 189, Issue 9, Page(s) E341–E364

Abstract: Background: Telemedicine, the use of telecommunications to deliver health services, expertise and information, is a promising but unproven tool for improving the quality of diabetes care. We summarized the effectiveness of different methods of ... ...

Abstract	Background: Telemedicine, the use of telecommunications to deliver health services, expertise and information, is a promising but unproven tool for improving the quality of diabetes care. We summarized the effectiveness of different methods of telemedicine for the management of diabetes compared with usual care. Methods: We searched MEDLINE, Embase and the Cochrane Central Register of Controlled Trials databases (to November 2015) and reference lists of existing systematic reviews for randomized controlled trials (RCTs) comparing telemedicine with usual care for adults with diabetes. Two independent reviewers selected the studies and assessed risk of bias in the studies. The primary outcome was glycated hemoglobin (HbA Results: From 3688 citations, we identified 111 eligible RCTs ( Interpretation: Compared with usual care, the addition of telemedicine, especially systems that allowed medication adjustments with or without text messaging or a Web portal, improved HbA
MeSH term(s)	Communication ; Diabetes Mellitus/blood ; Diabetes Mellitus/therapy ; Disease Management ; Glycated Hemoglobin/analysis ; Humans ; Hypoglycemia/blood ; Hypoglycemia/prevention & control ; Internet ; Quality of Life ; Randomized Controlled Trials as Topic ; Telemedicine ; Text Messaging
Chemical Substances	Glycated Hemoglobin A
Language	English
Publishing date	2016-10-31
Publishing country	Canada
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ZDB-ID	215506-0
ISSN	1488-2329 ; 0008-4409 ; 0820-3946
ISSN (online)	1488-2329
ISSN	0008-4409 ; 0820-3946
DOI	10.1503/cmaj.150885
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Article: The value of serum uric Acid as a mortality prediction in critically ill children.

Hooman, Nakysa / Mehrazma, Mitra / Nakhaii, Shahrbanoo / Otukesh, Hasan / Moradi-Lakeh, Maziar / Dianati-Maleki, Neda / Ehteshami-Afshar, Arash

Iranian journal of pediatrics

2012 Volume 20, Issue 3, Page(s) 323–329

Abstract: Objective: The role of initial serum uric acid on admission in critically ill patients is controversial; we presumed that uric acid level can predict the mortality of the admitted patients to intensive care unit as a simple test.: Methods: Totally, ... ...

Abstract	Objective: The role of initial serum uric acid on admission in critically ill patients is controversial; we presumed that uric acid level can predict the mortality of the admitted patients to intensive care unit as a simple test. Methods: Totally, 220 consecutively admitted children (96 girls, 124 boys) with mean age 3.5 years, who were at least 24 hours in pediatric intensive care unit (PICU), were enrolled in a prospective cohort study during January 2006 to December 2007. The subsequent PICU admission in the same hospitalization, those who were discharged from the hospital and then re-admitted to the PICU during the observation period, and the patients with chronic renal failure were excluded. Serum uric acid level was measured during the first day of PICU admission. Death or transfer from PICU was considered as final outcome. The statistical analysis was done by using linear regression analysis, ROC curve, Student t-test, and Chi- square. P value less than 0.05 was considered significant. Findings: From 44 patients who had serum uric acid level more than 8 mg/dl, 17 cases died showing with a higher relative risk of 1.88, higher mortality (P<0.05). The relative risk of death in patients who had serum uric acid >8 mg/dl and needed vasopressor was 1.04, and in those under mechanical ventilation 1.33. In patients who scored pediatric risk of mortality of >38 it was 1.4, and in septic cases 4 (P<0.05). Stepwise linear regression analysis showed that mainly the need for mechanical ventilation (P=0.001) and vasopressor had statistically significant correlation with the poor outcome (P=0.001). Conclusion: Uric acid level during the first day of intensive critical care admission is not an independent risk of mortality in PICU. Need for mechanical ventilation or inotropic agents was associated with poor outcome and only higher uric acid level in sepsis played an additive risk factor role.
Language	English
Publishing date	2012-09-27
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2388780-1
ISSN	2008-2150 ; 2008-2142
ISSN (online)	2008-2150
ISSN	2008-2142
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