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  1. Article: STUDY OF THE HEMOMICROCIRCULATORY CHANNEL IN PATIENTS WITH DIABETES AND THREATENING ISCHEMIA OF THE LOWER LIMB.

    Didenko, S / Subbotin, V / Hupalo, Yu / Ivanko, O / Orlych, O

    Georgian medical news

    2023  , Issue 337, Page(s) 85–88

    Abstract: Purpose of work - to investigate the hem microcirculatory channel (HCMC) in chronic critical lower extremity ischemia (CHLIC) in patients with diabetes mellitus (DM). To develop a method for calculating the indicator of the degree of diabetic ... ...

    Abstract Purpose of work - to investigate the hem microcirculatory channel (HCMC) in chronic critical lower extremity ischemia (CHLIC) in patients with diabetes mellitus (DM). To develop a method for calculating the indicator of the degree of diabetic microangiopathy (PSDMAP). Skin and muscle samples of 63 patients with type 2 diabetes mellitus with CKD and skin and muscle samples of 30 patients without systemic diseases. Histological and immunohistochemical studies were conducted to detect type IV collagen, CD31, and smooth muscle action. We measured the diameters of blood vessels of the skin and muscles, the density of capillaries per unit area for the calculation of PSDMAP. Characteristic changes were revealed in the morphometric parameters of the HCMC of the skin in patients with type II diabetes mellitus with CKD. A method for calculating PSDMAP was developed. It was revealed a correlation between the type of diabetic microangiopathy and the probability of thrombosis after hybrid arterial reconstruction, and an algorithm for the examination of patients in the postoperative period was developed.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/complications ; Microcirculation ; Lower Extremity ; Ischemia ; Diabetic Angiopathies ; Renal Insufficiency, Chronic
    Language English
    Publishing date 2023-06-22
    Publishing country Georgia (Republic)
    Document type Journal Article
    ZDB-ID 2443648-3
    ISSN 1512-0112
    ISSN 1512-0112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [HYBRID SURGICAL INTERVENTIONS IN PATIENTS FOR ISHEMICAL FORMS OF DIABETIC FOOT SYNDROME].

    Didenko, S M

    Klinichna khirurhiia

    2018  , Issue 7, Page(s) 27–29

    Abstract: The experience of the hybrid surgical interventions performing in 24 patients with diabetes mellitus type II of complicated ischemic form of diabetic foot syndrome was adduced. According to the results of preoperative examination of ... ...

    Abstract The experience of the hybrid surgical interventions performing in 24 patients with diabetes mellitus type II of complicated ischemic form of diabetic foot syndrome was adduced. According to the results of preoperative examination of patients showed a multilevel occlusive—stenotic lesions of the lower limb arteries. The hybrid arterial reconstruction operations performing has improved the results of surgical treatment of such patients.
    MeSH term(s) Aged ; Amputation/methods ; Angiography ; Blood Flow Velocity ; Constriction, Pathologic ; Diabetic Foot/diagnostic imaging ; Diabetic Foot/pathology ; Diabetic Foot/surgery ; Female ; Femoral Artery/diagnostic imaging ; Femoral Artery/pathology ; Femoral Artery/surgery ; Humans ; Ischemia/diagnostic imaging ; Ischemia/pathology ; Ischemia/surgery ; Limb Salvage/methods ; Lower Extremity/blood supply ; Lower Extremity/diagnostic imaging ; Lower Extremity/pathology ; Lower Extremity/surgery ; Male ; Middle Aged ; Popliteal Artery/diagnostic imaging ; Popliteal Artery/pathology ; Popliteal Artery/surgery ; Reconstructive Surgical Procedures/methods ; Tibial Arteries/diagnostic imaging ; Tibial Arteries/pathology ; Tibial Arteries/surgery ; Vascular Surgical Procedures/methods
    Language Ukrainian
    Publishing date 2018-09-25
    Publishing country Ukraine
    Document type Journal Article
    ZDB-ID 411775-x
    ISSN 0023-2130
    ISSN 0023-2130
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  3. Article: [VALUE OF INTRAOPERATIVE DEBITOMETRY IN SELECTING OF SURGICAL TREATMENT TACTICS FOR PATIENTS WITH DIABETES MELLITUS WITH CHRONIC CRITICAL ISCHEMIA OF THE LOWER LIMB].

    Didenko, S / Subbotin, V / Ratushniuk, A / Prysyazhna, N / Khalimovskyi, B

    Georgian medical news

    2021  , Issue 316-317, Page(s) 10–16

    Abstract: Aim - analyze the results of surgical treatment of patients with diabetes mellitus (DM) with chronic critical lower limb ischemia (CCLLI) against the background of the combined stenotic-occlusive lesions (SOL) of the femoral arterial segment (FAS) and ... ...

    Abstract Aim - analyze the results of surgical treatment of patients with diabetes mellitus (DM) with chronic critical lower limb ischemia (CCLLI) against the background of the combined stenotic-occlusive lesions (SOL) of the femoral arterial segment (FAS) and popliteo-tibial arterial segment (PTAS), considering the data of the intraoperative debitometry (ID). The results of surgical treatment of 97 patients with diabetes mellitus with CCLLI caused by combined SOL of FAS and PTAS arteries after 1 month and 12 months of treatment were analyzed. All patients were treated at the Vascular Surgery Center of the Clinical Hospital "Feofania" of State Directorate for Affairs, Kiev, Ukraine during 2014 - 2018yrs. All patients underwent femoro-popliteal bypass grafting without intervention on arteries of PTAS.According to the obtained results of the ID, the patients were divided into groups: group 1 - 32 patients with a debit of the shunt (SD) greater than 60 ml/min, group 2 - 35 patients with SD 30-60 ml/min, group 3 - 30 patients with SD lesser than 30 ml/min. In case of the femoro-popliteal shunt (FPS) thrombosis, performed repeated surgery as a hybrid revascularization (HR) - thrombectomy from the shunt and endovascular balloon angioplasty of the arteries of PTAS. The primary patency of the arterial reconstruction zone of the patients from group 1 after 1 month was 93.75% (30 of 32), after 12 months - 78.13% (25 of 32); group 2 - after 1 month it was 82.8% (29 out of 35), after 12 months - 68.57% (24 out of 35); group 3 - after 1 month it was 46.66% (14 out of 30), after 12 months - 23.33% (7 out of 30). Thrombosis of the femoropopliteal shunt (FPS) within 12 months was diagnosed in 41 (42.27%) of 97 patients, within these patients 1 month after primary shunting in 26 (63.41%), and during the next 11 months in 15 (36.59 %)cases.With repeated intervention on thrombosis ofFPSin form ofHR, secondary patency within 12 months was 78.05% (32 of 41 patients).Restoration of the outflow from the popliteal artery in one of the tibial arteries by HR was possible in 28 of 41 (68.29%) patients, within 12 months rethrombosis of the arterial reconstruction zone occurred in 8 patients (28.57%) - with secondary patency after 12 months of 71.43% (20 of 28 patients). The restoration of the outflow from the popliteal artery into two tibial arteries by HR was possible in 13 of 41 (31.71%) patients, from them rethrombosis of the FPS within 12 months occurred in 1 patient (7.69%) - the secondary patency within 12 months was 92.31% (12 of 13 patients). In the case of combined SOL of FAS and arteries of PTAS, reconstruction of FAS without intervention on the arteries of PTAS requires performing of ID with determining of SD. Performing of ID with determining of SD is an effective diagnostic technique that allows to formulate a differentiated approach to the tactics of surgical treatment of patients with diabetes mellitus with CCLLI, caused by the SOL of FAS and PTAS. The indicator which allows to restore the patency of FAS without intervention on the arteries of the PTAS is SD>60 ml/min; with SD 30-60 ml/min, the reconstruction of the arteries of the PTAS after the restoration of the patency of FAS can be delayed and performed as elective surgery at the second stage; with SD<30 ml/min, simultaneous reconstruction of FAS and PTAS arteries is required by performing HR or two-stage open arterial reconstruction. The HR is an effective method of blood circulation restoration in patients with diabetes mellitus with CCLLI, caused by a combined SOL of FAS and PTAS, and according to the results: the patency of the FPS within 12 months is 78.05% and does not significantly differ from the results of FAS reconstruction in 1st group of patients with SD>60 ml/min - where patency of the FPS within 12 months is 78.13% (p>0.05). In case of thrombosis of the FPS, thrombectomy from the shunt, supplemented by the restoration of the magistral blood flow from the popliteal artery into two tibial arteriesby the method of balloon angioplasty, demonstrates reliably better secondary patency of the femoropopliteal shunt after 12 months - 92.31% in comparison with the secondary patency of the FPS within 12 months after restoration of the magistral blood flow from the popliteal artery into one tibial artery - 71.43% (p<0.05).
    MeSH term(s) Diabetes Mellitus ; Humans ; Ischemia/surgery ; Lower Extremity/surgery ; Popliteal Artery/surgery ; Retrospective Studies ; Stents ; Treatment Outcome ; Vascular Patency
    Language Russian
    Publishing date 2021-09-12
    Publishing country Georgia (Republic)
    Document type Journal Article
    ZDB-ID 2443648-3
    ISSN 1512-0112
    ISSN 1512-0112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Protection of rare species of Caucasian flora in M.M. Gryshko National Botanical Garden of the NAS of Ukraine

    Didenko, S.Ya

    Ìntrodukcìâ roslin. 2018, v. 80

    2018  

    Abstract: Objective – to study the species composition and the state of introducing populations of plants of Caucasian flora on the botanical and geographic plant Caucasus of M.M. Gryshko National Botanical Garden of the NAS of Uk raine (NBG). Material and methods. ...

    Abstract Objective – to study the species composition and the state of introducing populations of plants of Caucasian flora on the botanical and geographic plant Caucasus of M.M. Gryshko National Botanical Garden of the NAS of Uk raine (NBG). Material and methods. The research was conducted in 2015–2018 at the territory of NBG during the inventory of the collection fund of the botanical and geographic plot Caucasus. The age structure of populations was studied by the method of T.O. Rabotnov and school of O.O. Uranov. Results. Summing up the 69 years of introduction of the Caucasian flora in the NBG. Conclusions. At the botanical and geographic plot Caucasus more than 1500 species of plants of natural flora of the Caucasus have been tested. Currently, the species composition of the site has 363 species, 116 of them are rare, 150 species have created stable introductive po pu lations. The collection is being replenished with new species for the area, which are successfully tested and become part of the floristic groupings of the plot.
    Keywords age structure ; botanical gardens ; flora ; inventories ; new species ; rare species ; species diversity ; Caucasus region ; Ukraine
    Language English
    Publishing place NAS of Ukraine, M.M. Gryshko National Botanical Garden
    Document type Article
    ISSN 2663-290X
    DOI 10.5281/zenodo.2576057
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Spring ephemeroids of Caucasus flora in nature and culture in M.M. Gryshko National Botanical Garden of the NАS of Ukraine

    Didenko, S. Ja

    Ìntrodukcìâ roslin. 2017, v. 74

    2017  

    Abstract: Objective – to increase the efficiency of introduction of rare Caucasus flora spring ephemeroids (Cyclamen coum Rehb., Helleborus caucasicus A. Braun, Erytronium caucasicum Woronow, Ornithogalum arcuatum Stev., O. ponticum Zahar.) at M.M. Gryshko ... ...

    Abstract Objective – to increase the efficiency of introduction of rare Caucasus flora spring ephemeroids (Cyclamen coum Rehb., Helleborus caucasicus A. Braun, Erytronium caucasicum Woronow, Ornithogalum arcuatum Stev., O. ponticum Zahar.) at M.M. Gryshko National Botanical Garden of NАS of Ukraine. Material and methods. In 2011 and 2012 years expeditions were made the trip to the Caucasus for study of natural populations of these species. Comparison of natural and introduction populations, that evolved over several decades in M.M. Gryshko National Botanical Garden of NАS of Ukraine is carried out. Results. All studied species grow well, blossom and bear fruit, formed a stable population of introduction. Only C. coum require artificial support. Conclusion. The study of natural populations allows not only to compare growth conditions and the state of introduction populations from their natural counterparts, but also make the introduction of more effective.
    Keywords Cyclamen coum ; Helleborus ; Ornithogalum ; Ursidae ; botanical gardens ; ephemeral plants ; flora ; fruits ; spring ; Caucasus region ; Ukraine
    Language English
    Publishing place NAS of Ukraine, M.M. Gryshko National Botanical Garden
    Document type Article
    ISSN 2663-290X
    DOI 10.5281/zenodo.2299244
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Evaluation of introduction of Caucasian flora species in conditions of M.M. Gryshko National Botanical Garden of the NАS of Ukraine

    Didenko, S.Ja

    Ìntrodukcìâ roslin. 2016, v. 72

    2016  

    Abstract: Since 1949, when it was laid botanical-geographical plot “Caucasus”, species composition replenished through research expedition S.S. Kharkevich. Since then many years have passed. Not all of species have survived. Many species form a population of ... ...

    Abstract Since 1949, when it was laid botanical-geographical plot “Caucasus”, species composition replenished through research expedition S.S. Kharkevich. Since then many years have passed. Not all of species have survived. Many species form a population of introduction. The behavior of some species has a fluctuating character. Some species, for various reasons remained small. Therefore, collection of plant species of Caucasus flora requires careful study and find ways to support new species in terms of Kyiv. The results of the introduction of herbaceous plants of the flora of the Caucasus in botanical and geographical plot “Caucasus” and evaluated its performance. Updated work to replenish the collection with new species.
    Keywords botanical gardens ; flora ; new species ; species diversity ; Caucasus region ; Ukraine
    Language English
    Publishing place NAS of Ukraine, M.M. Gryshko National Botanical Garden
    Document type Article
    ISSN 2663-290X
    DOI 10.5281/zenodo.2457171
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  7. Article: State of introductory populations of Galanthus L. species (Amaryllidaceae) of the flora of Caucasus in conditios of Kyiv. Part 2. Species of wide area

    Didenko, S.Ya

    Ìntrodukcìâ roslin. 2014, v. 62

    2014  

    Abstract: The work on introduction of some species belong to the genus Galanthus L. of the Caucasus flora have been conducted during 62 years on the botanical and geographical plot Caucasus of M.M. Gryshko National Botanical Garden of the NAS of Ukraine are shown. ...

    Abstract The work on introduction of some species belong to the genus Galanthus L. of the Caucasus flora have been conducted during 62 years on the botanical and geographical plot Caucasus of M.M. Gryshko National Botanical Garden of the NAS of Ukraine are shown. The results of two years study of snowdrops natural populations in the Caucasus are given.
    Keywords Galanthus ; botanical gardens ; flora ; Caucasus region ; Ukraine
    Language English
    Publishing place NAS of Ukraine, M.M. Gryshko National Botanical Garden
    Document type Article
    ISSN 2663-290X
    DOI 10.5281/zenodo.1494304
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  8. Article: [The case of hairy cell leukosis in pediatrics].

    Murashkina, O E / Sklyarova, R E / Didenko, S N

    Klinicheskaia laboratornaia diagnostika

    2018  Volume 61, Issue 4, Page(s) 223–225

    Abstract: According publications' data, hairy cell leukosis encounters in humans aged from 26 to 70 years and in males four times more often than in females. The disease is manifested by impotence, splenomegaly, and presence in blood and bone marrow clone of ... ...

    Abstract According publications' data, hairy cell leukosis encounters in humans aged from 26 to 70 years and in males four times more often than in females. The disease is manifested by impotence, splenomegaly, and presence in blood and bone marrow clone of lymphoid cells with particular morphology, cytochemic markers and immune phenotype (sIg+, CD19+, CD20+, CD5-, CD10-, with marked expression of CD25+, CD103+). The presented clinical case of illness with hairy cell leucosis is the first one detected in pediatric practice in adolescent of 16 years old.
    MeSH term(s) Acid Phosphatase/blood ; Adolescent ; Antigens, CD/blood ; Antigens, CD19/blood ; Antigens, CD20/blood ; B-Lymphocytes/pathology ; Female ; Flow Cytometry ; Humans ; Integrin alpha Chains/blood ; Interleukin-2 Receptor alpha Subunit/blood ; Isoenzymes/blood ; Leukemia, Hairy Cell/blood ; Leukemia, Hairy Cell/pathology ; Lymphocytes/pathology
    Chemical Substances Antigens, CD ; Antigens, CD19 ; Antigens, CD20 ; Integrin alpha Chains ; Interleukin-2 Receptor alpha Subunit ; Isoenzymes ; alpha E integrins ; Acid Phosphatase (EC 3.1.3.2)
    Language Russian
    Publishing date 2018-12-25
    Publishing country Russia (Federation)
    Document type Case Reports ; Journal Article
    ZDB-ID 1155086-7
    ISSN 0869-2084
    ISSN 0869-2084
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  9. Article ; Online: A CMOS compatible thermoelectric device made of crystalline silicon membranes with nanopores.

    Bah, Thierno-Moussa / Didenko, Stanislav / Zhou, Di / Zhu, Tianqi / Ikzibane, Hafsa / Monfray, Stephane / Skotnicki, Thomas / Dubois, Emmanuel / Robillard, Jean-François

    Nanotechnology

    2022  Volume 33, Issue 50

    Abstract: Herein, we report the use of nanostructured crystalline silicon as a thermoelectric material and its integration into thermoelectric devices. The proof-of-concept relies on the partial suppression of lattice thermal conduction by introducing pores with ... ...

    Abstract Herein, we report the use of nanostructured crystalline silicon as a thermoelectric material and its integration into thermoelectric devices. The proof-of-concept relies on the partial suppression of lattice thermal conduction by introducing pores with dimensions scaling between the electron mean free path and the phonon mean free path. In other words, we artificially aimed at the well-known 'electron crystal and phonon glass' trade-off targeted in thermoelectricity. The devices were fabricated using CMOS-compatible processes and exhibited power generation up to 5.5 mW cm
    Language English
    Publishing date 2022-09-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ac8d12
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  10. Article: [The application of methods of physical therapy in the military health resort].

    Titov, I G / Didenko, S V

    Voenno-meditsinskii zhurnal

    2015  Volume 336, Issue 3, Page(s) 47–52

    Abstract: Presented the main guidelines concerning the application of methods and forms of physical therapy in the complex sanatorium treatment and rehabilitation in sanatoria and health resorts of the Ministry of Defence of the Russian Federation. It is concluded ...

    Abstract Presented the main guidelines concerning the application of methods and forms of physical therapy in the complex sanatorium treatment and rehabilitation in sanatoria and health resorts of the Ministry of Defence of the Russian Federation. It is concluded that the basis for the application and further development of forms and methods of physical therapy should be based on the methodological principle of a differentiated approach to the assessment of the severity of dysfunction cardiorespiratory and nervous system, musculoskeletal system, the mode of motor activity and exercise tolerance.
    MeSH term(s) Health Resorts ; Humans ; Military Medicine/methods ; Military Personnel ; Physical Therapy Modalities ; Russia
    Language Russian
    Publishing date 2015-03
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 392041-0
    ISSN 0026-9050 ; 0300-9114
    ISSN 0026-9050 ; 0300-9114
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