Article: Legionnaire's disease presenting with encephalitis, myoclonus, and seizures: Successful treatment with doxycycline.
2019 Volume 17, Page(s) e00540
Abstract: Legionnaire's disease (LD) is a non-zoonotic atypical community acquired pneumonia (CAP) with several characteristic extra-pulmonary findings. Pending diagnostic test results, selected characteristic findings when considered together are the basis of ... ...
| Abstract | Legionnaire's disease (LD) is a non-zoonotic atypical community acquired pneumonia (CAP) with several characteristic extra-pulmonary findings. Pending diagnostic test results, selected characteristic findings when considered together are the basis of clinical syndromic diagnosis and the basis of empiric antimicrobial therapy. Of the extra-pulmonary manifestation of LD, neurologic findings are among the most common, e.g., headache, mental confusion. In LD, encephalitis is rare as are myoclonus and seizures. This is a most interesting case of LD that presented with encephalitis, myoclonus and seizures. Pulmonary infiltrates developed early after admission. LD was suspected on the basis of otherwise unexplained characteristic findings, e.g., hypophosphatemia, elevated serum transaminases, microscopic hematuria, elevated ferritin, and empiric doxycycline therapy was started. The diagnosis of LD was further supported by prominent and persistent myoclonus and seizures, rare but characteristic neurologic findings in LD. On week 12 of hospitalization, he finally seroconverted with negative urinary antigen tests indicating his LD was due to a non- |
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| Language | English |
| Publishing date | 2019-04-17 |
| Publishing country | Netherlands |
| Document type | Case Reports |
| ZDB-ID | 2745454-X |
| ISSN | 2214-2509 |
| ISSN | 2214-2509 |
| DOI | 10.1016/j.idcr.2019.e00540 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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