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  1. Book ; Thesis: Halbtechnische Entwicklung eines Verfahrens zur mikrobiellen Reinigung von mineralölkontaminierten Sandfangrückständen (10 t-Maßstab) aus der Großölabscheideranlage des Abwasserpumpwerkes in Ölper

    Dietzmann, Detlef

    2000  

    Author's details von Detlef Dietzmann
    Keywords Rückstand ; Technikumsanlage ; Mikrobieller Abbau ; Mineralöl ; Sandfang ; Abwasserpumpwerk
    Language German
    Size 226, [3] S., Ill., graph. Darst., 21 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Univ., Diss.--Braunschweig, 2000
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Thesis: Halbtechnische Entwicklung eines Verfahrens zur mikrobiellen Reinigung von mineralölkontaminierten Sandfangrückständen (10 t-Maßstab) aus der Großölabscheideranlage des Abwasserpumpwerkes in Ölper

    Dietzmann, Detlef

    2000  

    Author's details von Detlef Dietzmann
    Keywords Rückstand ; Technikumsanlage ; Mikrobieller Abbau ; Mineralöl ; Sandfang ; Abwasserpumpwerk
    Language German
    Size 226, [3] S., Ill., graph. Darst., 21 cm
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Techn. Univ., Diss.--Braunschweig, 2000
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book: Halbtechnische Entwicklung eines Verfahrens zur mikrobiellen Reinigung von mineraloelkontaminierten Sandfangrueckstaenden (10 t-Massstab) aus der Grossoelabscheideanlage des Abwasserpumpwerkes in Oelper

    Dietzmann, Detlef

    2000  , Page(s) 226 S., Anh.

    Language German
    Document type Book
    Database OPAC and Environmental database (ULIDAT) of The Federal Environment Agency (UBA)

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  4. Article ; Online: Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: Results of an international interlaboratory study.

    Hettwer, Karina / Jähne, Martin / Frost, Kirstin / Giersberg, Martin / Kunze, Gotthard / Trimborn, Michael / Reif, Martin / Türk, Jochen / Gehrmann, Linda / Dardenne, Freddy / De Croock, Femke / Abraham, Marion / Schoop, Anne / Waniek, Joanna J / Bucher, Thomas / Simon, Eszter / Vermeirssen, Etienne / Werner, Anett / Hellauer, Karin /
    Wallentits, Ursula / Drewes, Jörg E / Dietzmann, Detlef / Routledge, Edwin / Beresford, Nicola / Zietek, Tamara / Siebler, Margot / Simon, Anne / Bielak, Helena / Hollert, Henner / Müller, Yvonne / Harff, Maike / Schiwy, Sabrina / Simon, Kirsten / Uhlig, Steffen

    The Science of the total environment

    2017  Volume 621, Page(s) 612–625

    Abstract: Endocrine-active substances can adversely impact the aquatic ecosystems. A special emphasis is laid, among others, on the effects of estrogens and estrogen mimicking compounds. Effect-based screening methods like in vitro bioassays are suitable tools to ... ...

    Abstract Endocrine-active substances can adversely impact the aquatic ecosystems. A special emphasis is laid, among others, on the effects of estrogens and estrogen mimicking compounds. Effect-based screening methods like in vitro bioassays are suitable tools to detect and quantify endocrine activities of known and unknown mixtures. This study describes the validation of the Arxula-Yeast Estrogen Screen (A-YES®) assay, an effect-based method for the detection of the estrogenic potential of water and waste water. This reporter gene assay, provided in ready to use format, is based on the activation of the human estrogen receptor alpha. The user-friendly A-YES® enables inexperienced operators to rapidly become competent with the assay. Fourteen laboratories from four countries with different training levels analyzed 17β-estradiol equivalent concentrations (EEQ) in spiked and unspiked waste water effluent and surface water samples, in waste water influent and spiked salt water samples and in a mixture of three bisphenols. The limit of detection (LOD) for untreated samples was 1.8ng/L 17β-estradiol (E2). Relative repeatability and reproducibility standard deviation for samples with EEQ above the LOD (mean EEQ values between 6.3 and 20.4ng/L) ranged from 7.5 to 21.4% and 16.6 to 28.0%, respectively. Precision results are comparable to other frequently used analytical methods for estrogens. The A-YES® has been demonstrated to be an accurate, precise and robust bioassay. The results have been included in the ISO draft standard. The assay was shown to be applicable for testing of typical waste water influent, effluent and saline water. Other studies have shown that the assay can be used with enriched samples, which lower the LOD to the pg/L range. The validation of the A-YES® and the development of a corresponding international standard constitute a step further towards harmonized and reliable bioassays for the effect-based analysis of estrogens and estrogen-like compounds in water samples.
    MeSH term(s) Biological Assay ; Endocrine Disruptors ; Environmental Monitoring/methods ; Estradiol/analysis ; Estrogen Receptor alpha/metabolism ; Estrogens/analysis ; Humans ; Limit of Detection ; Phenols/analysis ; Reproducibility of Results ; Saccharomycetales ; Water Pollutants, Chemical/analysis
    Chemical Substances Endocrine Disruptors ; Estrogen Receptor alpha ; Estrogens ; Phenols ; Water Pollutants, Chemical ; Estradiol (4TI98Z838E)
    Language English
    Publishing date 2017-11-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2017.11.211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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