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  1. Article ; Online: Obstetrical and gynecologic implications of COVID-19: what have we learned over the first two years of the pandemic.

    Digby, Alyson M / Dahan, Michael H

    Archives of gynecology and obstetrics

    2023  Volume 308, Issue 3, Page(s) 813–819

    Abstract: The rapidly evolving nature of the coronavirus disease 2019 (COVID-19) pandemic has resulted in the publication of a breadth of information in the field of Obstetrics and Gynecology. This article is an examination of the impacts of COVID-19 on women's ... ...

    Abstract The rapidly evolving nature of the coronavirus disease 2019 (COVID-19) pandemic has resulted in the publication of a breadth of information in the field of Obstetrics and Gynecology. This article is an examination of the impacts of COVID-19 on women's health, specifically on pregnancy, fertility, and delays to care. We review, in brief, the clinical presentation, transmission, and definitions of post-COVID conditions. Additionally, this article explores the reassuring evidence published regarding the use of mRNA vaccines in preconception and fertility treatments.
    MeSH term(s) COVID-19/prevention & control ; Obstetrics ; Humans ; Female ; Pregnancy ; Gynecology ; Pandemics ; SARS-CoV-2 ; Fertilization in Vitro ; Fertility ; mRNA Vaccines ; Reproductive Health
    Chemical Substances mRNA Vaccines
    Language English
    Publishing date 2023-01-12
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-022-06847-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Um I Zs.55: Show issues Location:
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  2. Article ; Online: The prognosis of pediatric headaches--a 30-year follow-up study.

    Dooley, Joseph M / Augustine, Haley F / Brna, Paula M / Digby, Alyson M

    Pediatric neurology

    2014  Volume 51, Issue 1, Page(s) 85–87

    Abstract: Background: Although headaches in childhood are common, there are few data available on their long-term prognosis. We have monitored a group of patients since diagnosis in 1983.: Methods: Patients who were part of the 20-year follow-up study in 2003 ... ...

    Abstract Background: Although headaches in childhood are common, there are few data available on their long-term prognosis. We have monitored a group of patients since diagnosis in 1983.
    Methods: Patients who were part of the 20-year follow-up study in 2003 were contacted, and data were collected using a standardized telephone interview. Details of headache characteristics and identified precipitants and alleviating factors were gathered. The most effective means of controlling the headaches were also recorded.
    Results: Follow-up was achieved for 28 of 60 patients (47%). Over the 30 years since diagnosis, eight patients (29%) reported a complete resolution of headaches, including three whose headaches resolved between the 20- and 30-year follow-up studies. The type of headache varied over the 30-year time interval with only three patients maintaining the same headache type at all four time periods of 1983, 1993, 2003, and 2013. Only one patient used prescription medication as the primary method for controlling headaches. The most commonly used intervention was nonprescription analgesia, self-relaxation and/or hypnosis, and precipitant avoidance.
    Conclusions: Headaches persist in approximately 70% of children 30 years after diagnosis. Encouraging children to manage their headaches with simple analgesia and precipitant avoidance appears to have long-term benefits.
    MeSH term(s) Adult ; Female ; Headache/diagnosis ; Headache/epidemiology ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Pediatrics ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2014.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Dexamethasone Given to Premature Infants and Cardiac Diastolic Function in Early Childhood

    Wong, Ivan H.-B / Digby, Alyson M / Warren, Andrew E / Pepelassis, Dion / Vincer, Michael / Chen, Robert P.-C

    journal of pediatrics. 2011 Aug., v. 159, no. 2

    2011  

    Abstract: OBJECTIVES: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans. STUDY DESIGN: We compared seven children ages 3 to 8 years ...

    Abstract OBJECTIVES: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans. STUDY DESIGN: We compared seven children ages 3 to 8 years born at 26 weeks’ gestation and given dexamethasone for bronchopulmonary dysplasia with eight gestation-matched and age-matched control children using echocardiography to assess measures of systolic and diastolic function. All dexamethasone patients had resolved hypertrophic cardiomyopathy. RESULTS: Dexamethasone patients had the same normal τ and isovolumic relaxation time (24.9 ± 2.8 and 54.6 ± 6.3 ms) as control patients (22.1 ± 3.0 and 48.8 ± 6.7 ms). Peak A velocities were the same in dexamethasone patients as in control patients (59.5 ± 15 versus 49.4 ± 5.8 cm/s, P = .10), resulting in unchanged E:A ratios (1.89 ± 0.57 versus 2.15 ± 0.43, P = .22). Peak E velocity and E-wave deceleration times were not different. We found no significant differences in measures of systolic function (heart rate–corrected velocity of circumferential fiber shortening, wall stress, and ejection fraction). Left ventricular mass was the same between the groups confirming resolution of hypertrophic cardiomyopathy. CONCLUSIONS: These data are consistent with normal myocardial relaxation, suggesting that long-term diastolic function is reassuringly normal in children who received dexamethasone as premature infants with resolution of hypertrophic cardiomyopathy.
    Keywords bronchopulmonary dysplasia ; cardiomyopathy ; childhood ; children ; dexamethasone ; echocardiography ; heart ; humans ; infants ; patients ; pregnancy
    Language English
    Dates of publication 2011-08
    Size p. 227-231.
    Publishing place Mosby, Inc.
    Document type Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2011.01.008
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Dexamethasone given to premature infants and cardiac diastolic function in early childhood.

    Wong, Ivan H-B / Digby, Alyson M / Warren, Andrew E / Pepelassis, Dion / Vincer, Michael / Chen, Robert P-C

    The Journal of pediatrics

    2011  Volume 159, Issue 2, Page(s) 227–231

    Abstract: Objectives: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans.: Study design: We compared seven children ages 3 to 8 ... ...

    Abstract Objectives: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans.
    Study design: We compared seven children ages 3 to 8 years born at 26 weeks' gestation and given dexamethasone for bronchopulmonary dysplasia with eight gestation-matched and age-matched control children using echocardiography to assess measures of systolic and diastolic function. All dexamethasone patients had resolved hypertrophic cardiomyopathy.
    Results: Dexamethasone patients had the same normal τ and isovolumic relaxation time (24.9 ± 2.8 and 54.6 ± 6.3 ms) as control patients (22.1 ± 3.0 and 48.8 ± 6.7 ms). Peak A velocities were the same in dexamethasone patients as in control patients (59.5 ± 15 versus 49.4 ± 5.8 cm/s, P = .10), resulting in unchanged E:A ratios (1.89 ± 0.57 versus 2.15 ± 0.43, P = .22). Peak E velocity and E-wave deceleration times were not different. We found no significant differences in measures of systolic function (heart rate-corrected velocity of circumferential fiber shortening, wall stress, and ejection fraction). Left ventricular mass was the same between the groups confirming resolution of hypertrophic cardiomyopathy.
    Conclusions: These data are consistent with normal myocardial relaxation, suggesting that long-term diastolic function is reassuringly normal in children who received dexamethasone as premature infants with resolution of hypertrophic cardiomyopathy.
    MeSH term(s) Bronchopulmonary Dysplasia/complications ; Bronchopulmonary Dysplasia/drug therapy ; Cardiomyopathy, Hypertrophic/drug therapy ; Cardiomyopathy, Hypertrophic/etiology ; Cardiomyopathy, Hypertrophic/physiopathology ; Child ; Child, Preschool ; Dexamethasone/administration & dosage ; Diastole ; Female ; Follow-Up Studies ; Glucocorticoids/administration & dosage ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/drug therapy ; Intensive Care Units, Neonatal ; Male ; Myocardial Contraction/drug effects ; Recovery of Function ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Ventricular Function/drug effects ; Ventricular Function/physiology
    Chemical Substances Glucocorticoids ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2011-08
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2011.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Um IV Zs.116: Show issues Location:
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  5. Article: Dexamethasone Given to Premature Infants and Cardiac Diastolic Function in Early Childhood

    Wong, Ivan H.-B. / Digby, Alyson M. / Warren, Andrew E. / Pepelassis, Dion / Vincer, Michael / Chen, Robert P.-C.

    journal of pediatrics

    Volume v. 159,, Issue no. 2

    Abstract: OBJECTIVES: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans. STUDY DESIGN: We compared seven children ages 3 to 8 years ...

    Abstract OBJECTIVES: To determine if dexamethasone given to premature infants with bronchopulmonary dysplasia would result in cardiac diastolic dysfunction in early childhood, a topic unstudied in humans. STUDY DESIGN: We compared seven children ages 3 to 8 years born at 26 weeks’ gestation and given dexamethasone for bronchopulmonary dysplasia with eight gestation-matched and age-matched control children using echocardiography to assess measures of systolic and diastolic function. All dexamethasone patients had resolved hypertrophic cardiomyopathy. RESULTS: Dexamethasone patients had the same normal τ and isovolumic relaxation time (24.9 ± 2.8 and 54.6 ± 6.3 ms) as control patients (22.1 ± 3.0 and 48.8 ± 6.7 ms). Peak A velocities were the same in dexamethasone patients as in control patients (59.5 ± 15 versus 49.4 ± 5.8 cm/s, P = .10), resulting in unchanged E:A ratios (1.89 ± 0.57 versus 2.15 ± 0.43, P = .22). Peak E velocity and E-wave deceleration times were not different. We found no significant differences in measures of systolic function (heart rate–corrected velocity of circumferential fiber shortening, wall stress, and ejection fraction). Left ventricular mass was the same between the groups confirming resolution of hypertrophic cardiomyopathy. CONCLUSIONS: These data are consistent with normal myocardial relaxation, suggesting that long-term diastolic function is reassuringly normal in children who received dexamethasone as premature infants with resolution of hypertrophic cardiomyopathy.
    Keywords dexamethasone ; patients ; heart ; bronchopulmonary dysplasia ; pregnancy ; children ; cardiomyopathy ; humans ; childhood ; infants ; echocardiography
    Language English
    Document type Article
    ISSN 0022-3476
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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