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  1. Article ; Online: Role of practice standardization in outcome optimization for CDH.

    Dimmer, Alexandra / Baird, Robert / Puligandla, Pramod

    World journal of pediatric surgery

    2024  Volume 7, Issue 2, Page(s) e000783

    Abstract: Standardization of care seeks to improve patient outcomes and healthcare delivery by reducing unwanted variations in care as well as promoting the efficient and effective use of healthcare resources. There are many types of standardization, with clinical ...

    Abstract Standardization of care seeks to improve patient outcomes and healthcare delivery by reducing unwanted variations in care as well as promoting the efficient and effective use of healthcare resources. There are many types of standardization, with clinical practice guidelines (CPGs), based on a stringent assessment of evidence and expert consensus, being the hallmark of high-quality care. This article outlines the history of CPGs, their benefits and shortcomings, with a specific focus on standardization efforts as it relates to congenital diaphragmatic hernia management.
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2516-5410
    ISSN (online) 2516-5410
    DOI 10.1136/wjps-2024-000783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Percutaneous extraction of metallic foreign body from pyogenic liver abscess.

    Basin, Michael / Dimmer, Alexandra / Abramyan, Shogik / Tewari, Sanjit O / Lucia, Amie

    Journal of surgical case reports

    2022  Volume 2022, Issue 8, Page(s) rjac349

    Abstract: We report a case of a 35-year-old male who developed a pyogenic liver abscess (PLA) secondary to a foreign body that migrated from the transverse colon into the liver. The mainstay of treatment of PLA requires removal of the foreign body, most frequently ...

    Abstract We report a case of a 35-year-old male who developed a pyogenic liver abscess (PLA) secondary to a foreign body that migrated from the transverse colon into the liver. The mainstay of treatment of PLA requires removal of the foreign body, most frequently performed surgically. Few case reports exist of percutaneous removal. As our patient was hemodynamically stable at time of presentation, he underwent successful percutaneous transhepatic removal of the foreign body, avoiding any need for surgical operation.
    Language English
    Publishing date 2022-08-10
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjac349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Disease severity impacts perceived quality of life in congenital diaphragmatic hernia: a prospective observational study.

    Dimmer, Alexandra / Meehan, Madison / Beauseigle, Sabrina / Koclas, Louise / Paquette, Katryn / Michel Macias, Carolina / Moore, Shiran S / Sant'Anna, Ana / Shapiro, Adam / Simoneau, Jessica / Villegas Martinez, Daniela / Altit, Gabriel / Puligandla, Pramod

    Archives of disease in childhood

    2024  

    Abstract: Background: While research indicates comparable quality of life (QOL) in congenital diaphragmatic hernia (CDH) and healthy populations, the effect of CDH severity on patients' health perceptions remains unexplored. We aimed to assess QOL perception in ... ...

    Abstract Background: While research indicates comparable quality of life (QOL) in congenital diaphragmatic hernia (CDH) and healthy populations, the effect of CDH severity on patients' health perceptions remains unexplored. We aimed to assess QOL perception in CDH, hypothesising a decline correlated with increased disease severity.
    Methods: In this prospective observational study, we analysed patients with CDH aged 5 years and above participating in a longitudinal outpatient programme. We excluded bilateral CDH, genetic/syndromic conditions, prematurity and late diagnosis. Participants self-administered the age-adapted Pediatric Quality of Life Inventory (PedsQL) survey, covering four domains (physical, emotional, social, school). After enrolment, data were collected blind to severity status (larger defects denoting significant/'severe' disease). Repeated measurements were managed using a random mixed-effects model.
    Results: Of 34 participants (50% males) who completed the PedsQL, 10 provided measurements at two visits. Eight required a patch (type C), while 26 had primary repairs (type A=8; type B=18). Age at first evaluation was comparable across groups (no patch: median 11 (7-16), patch: 13 (8-15) years, p=0.78). Severe CDH correlated significantly with lower PedsQL scores (adjusted β: -18%, 95% CI -28%; -7%, adjusted for age at visit and sex). Lower scores specifically occurred in walking, exercising, social and academic functioning.
    Conclusion: Severe CDH significantly lowers QOL. This finding is crucial for resource allocation in long-term CDH health surveillance and advocates for regular inclusion of patient experiences in quality improvement efforts.
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2024-326906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Diagnosis and management of congenital diaphragmatic hernia: a 2023 update from the Canadian Congenital Diaphragmatic Hernia Collaborative.

    Puligandla, Pramod / Skarsgard, Erik / Baird, Robert / Guadagno, Elena / Dimmer, Alexandra / Ganescu, Olivia / Abbasi, Nimrah / Altit, Gabriel / Brindle, Mary / Fernandes, Sairvan / Dakshinamurti, Shyamala / Flageole, Helene / Hebert, Audrey / Keijzer, Richard / Offringa, Martin / Patel, Dylan / Ryan, Greg / Traynor, Michael / Zani, Augusto /
    Chiu, Priscilla

    Archives of disease in childhood. Fetal and neonatal edition

    2024  Volume 109, Issue 3, Page(s) 239–252

    Abstract: Objective: The Canadian Congenital Diaphragmatic Hernia (CDH) Collaborative sought to make its existing clinical practice guideline, published in 2018, into a 'living document'.: Design and main outcome measures: Critical appraisal of CDH literature ... ...

    Abstract Objective: The Canadian Congenital Diaphragmatic Hernia (CDH) Collaborative sought to make its existing clinical practice guideline, published in 2018, into a 'living document'.
    Design and main outcome measures: Critical appraisal of CDH literature adhering to Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Evidence accumulated between 1 January 2017 and 30 August 2022 was analysed to inform changes to existing or the development of new CDH care recommendations. Strength of consensus was also determined using a modified Delphi process among national experts in the field.
    Results: Of the 3868 articles retrieved in our search that covered the 15 areas of CDH care, 459 underwent full-text review. Ultimately, 103 articles were used to inform 20 changes to existing recommendations, which included aspects related to prenatal diagnosis, echocardiographic evaluation, pulmonary hypertension management, surgical readiness criteria, the type of surgical repair and long-term health surveillance. Fifteen new CDH care recommendations were also created using this evidence, with most related to the management of pain and the provision of analgesia and neuromuscular blockade for patients with CDH.
    Conclusions: The 2023 Canadian CDH Collaborative's clinical practice guideline update provides a management framework for infants and children with CDH based on the best available evidence and expert consensus.
    MeSH term(s) Infant ; Child ; Pregnancy ; Female ; Humans ; Hernias, Diaphragmatic, Congenital/diagnostic imaging ; Hernias, Diaphragmatic, Congenital/therapy ; Canada ; Prenatal Diagnosis ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/therapy ; Hypertension
    Language English
    Publishing date 2024-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2007331-8
    ISSN 1468-2052 ; 1359-2998
    ISSN (online) 1468-2052
    ISSN 1359-2998
    DOI 10.1136/archdischild-2023-325865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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