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  1. Article ; Online: Octadentate Oxine-Armed Bispidine Ligand for Radiopharmaceutical Chemistry.

    Choudhary, Neha / Dimmling, Alexander / Wang, Xiaozhu / Southcott, Lily / Radchenko, Valery / Patrick, Brian O / Comba, Peter / Orvig, Chris

    Inorganic chemistry

    2019  Volume 58, Issue 13, Page(s) 8685–8693

    Abstract: In this study, we present the synthesis and characterization of the octadentate bispidine ligand, ... ...

    Abstract In this study, we present the synthesis and characterization of the octadentate bispidine ligand, H
    MeSH term(s) Animals ; Bridged Bicyclo Compounds, Heterocyclic/blood ; Bridged Bicyclo Compounds, Heterocyclic/chemical synthesis ; Bridged Bicyclo Compounds, Heterocyclic/chemistry ; Chelating Agents/chemical synthesis ; Chelating Agents/chemistry ; Coordination Complexes/blood ; Coordination Complexes/chemical synthesis ; Coordination Complexes/chemistry ; Drug Stability ; Humans ; Indium Radioisotopes ; Ligands ; Lutetium ; Mice ; Molecular Structure ; Oxyquinoline/analogs & derivatives ; Oxyquinoline/blood ; Oxyquinoline/chemical synthesis ; Oxyquinoline/chemistry ; Radioisotopes ; Radiopharmaceuticals/blood ; Radiopharmaceuticals/chemical synthesis ; Radiopharmaceuticals/chemistry
    Chemical Substances Bridged Bicyclo Compounds, Heterocyclic ; Chelating Agents ; Coordination Complexes ; Indium Radioisotopes ; Ligands ; Radioisotopes ; Radiopharmaceuticals ; bispidine ; Lutetium (5H0DOZ21UJ) ; Oxyquinoline (5UTX5635HP) ; Lutetium-177 (BRH40Y9V1Q) ; Indium-111 (E9NGC49E0T)
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.9b01016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts.

    Cruz, Dana L / Pipalia, Nina / Mao, Shu / Gadi, Deepti / Liu, Gang / Grigalunas, Michael / O'Neill, Matthew / Quinn, Taylor R / Kipper, Andi / Ekebergh, Andreas / Dimmling, Alexander / Gartner, Carlos / Melancon, Bruce J / Wagner, Florence F / Holson, Edward / Helquist, Paul / Wiest, Olaf / Maxfield, Frederick R

    ACS pharmacology & translational science

    2021  Volume 4, Issue 3, Page(s) 1136–1148

    Abstract: Niemann-Pick disease type C1 (NPC1) is a rare genetic cholesterol storage disorder caused by mutations in ... ...

    Abstract Niemann-Pick disease type C1 (NPC1) is a rare genetic cholesterol storage disorder caused by mutations in the
    Language English
    Publishing date 2021-05-27
    Publishing country United States
    Document type Journal Article
    ISSN 2575-9108
    ISSN (online) 2575-9108
    DOI 10.1021/acsptsci.1c00033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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