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  1. Article ; Online: Does wealth equate to happiness? an 11-year panel data analysis exploring socio-economic indicators and social media metrics.

    Huang, Feng / Ding, Huimin / Han, Nuo / Li, Fumeng / Zhu, Tingshao

    PloS one

    2024  Volume 19, Issue 4, Page(s) e0301206

    Abstract: The Easterlin paradox questions the link between economic growth and national well-being, emphasizing the necessity to explore the impact of economic elasticity, income inequality, and their temporal and spatial heterogeneity on subjective happiness. ... ...

    Abstract The Easterlin paradox questions the link between economic growth and national well-being, emphasizing the necessity to explore the impact of economic elasticity, income inequality, and their temporal and spatial heterogeneity on subjective happiness. Despite the importance of these factors, few studies have examined them together, thus ongoing debates about the impact of economics on well-being persist. To fill this gap, our analysis utilizes 11 years of panel data from 31 provinces in China, integrating macroeconomic indicators and social media content to reassess the Easterlin paradox. We use GDP per capita and the Gini coefficient as proxies for economic growth and income inequality, respectively, to study their effects on the subjective well-being expressed by citizens on social media in mainland China. Our approach combines machine learning and fixed effects models to evaluate these relationships. Key findings include: (1) In temporal relationships, a 46.70% increase in GDP per capita implies a 0.38 increase in subjective well-being, while a 0.09 increase in the Gini coefficient means a 1.47 decrease in subjective well-being. (2) In spatial relationships, for every 46.70% increase in GDP per capita, subjective well-being rises by 0.51; however, this relationship is buffered by unfair distribution, and GDP per capita no longer significantly affects subjective well-being when the Gini index exceeds 0.609. This study makes a synthetic contribution to the debate on the Easterlin paradox, indicating that economic growth can enhance well-being if income inequality is kept below a certain level. Although these results are theoretically enlightening for the relationship between economics and national well-being globally, this study's sample comes from mainland China. Due to differences in cultural, economic, and political factors, further research is suggested to explore these dynamics globally.
    MeSH term(s) Humans ; Socioeconomic Factors ; Happiness ; Social Media ; Income ; Economic Development
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0301206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hydrazone-linked 2D porphyrinic covalent organic framework photocatalysis for visible light-driven aerobic oxidation of amines to imines

    Wu, Shujuan / Zhang, Yu-Fei / Ding, Huimin / Li, Xia / Lang, Xianjun

    Journal of colloid and interface science. 2022 Mar. 15, v. 610

    2022  

    Abstract: Covalent organic frameworks (COFs) have recently gained rising consideration for visible light photocatalysis. Their property could be accurately established with specific reactions in which the most investigated one turns out to be the aerobic oxidation ...

    Abstract Covalent organic frameworks (COFs) have recently gained rising consideration for visible light photocatalysis. Their property could be accurately established with specific reactions in which the most investigated one turns out to be the aerobic oxidation of amines. In this contribution, a hydrazone-linked 2D (two-dimensional) porphyrinic COF, Por-DETH-COF, was assembled from 5,10,15,20-tetrakis(4-benzaldehyde)porphyrin (p-Por-CHO) and 2,5-diethoxyterephthalohydrazide (DETH) and its photocatalytic activity was duly appraised with the aerobic oxidation of amines. Thereby, the red light-driven selective oxidation of benzyl amines to imines was obtained in very high conversions and selectivities with ambient air as the oxidant. Importantly, the photocatalytic system exhibited remarkable compatibility of functional groups and extensive scope of benzyl amines. Notably, the Por-DETH-COF photocatalyst displayed outstanding recyclability after five successive cycles. This work suggests that 2D COFs could contribute a unique juncture for selective organic transformations by photocatalysis.
    Keywords air ; imines ; light ; oxidants ; oxidation ; photocatalysis ; photocatalysts ; porphyrins
    Language English
    Dates of publication 2022-0315
    Size p. 446-454.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2021.12.024
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Tunable Light Field Modulations with Chip- and Fiber-Compatible Monolithic Dielectric Metasurfaces.

    Du, Bobo / Xu, Yunfan / Ding, Huimin / Jiang, Weitao / Zhang, Lei / Zhang, Yanpeng

    Nanomaterials (Basel, Switzerland)

    2022  Volume 13, Issue 1

    Abstract: Metasurfaces with a high engineering degree of freedom are promising building blocks for applications in metalenses, beam deflectors, metaholograms, sensing, and many others. Though the fundamental and technological challenges, proposing tunable ... ...

    Abstract Metasurfaces with a high engineering degree of freedom are promising building blocks for applications in metalenses, beam deflectors, metaholograms, sensing, and many others. Though the fundamental and technological challenges, proposing tunable metasurfaces is still possible. Previous efforts in this field are mainly taken on designing sophisticated structures with active materials introduced. Here, we present a generic kind of monolithic dielectric metasurfaces for tunable light field modulations. Changes in the period number and surrounding refractive index enable discrete and continuous modulations of spatial light fields, respectively. We exemplify this concept in monolithic Lithium Niobate metasurfaces for tunable metalenses and beam deflectors. The utilization of monolithic dielectric materials facilitates the ready integration of the metasurfaces with both chip and optical fiber platforms. This concept is not limited by the availability of active materials or expensive and time-consuming fabrication techniques, which can be applied to any transparent dielectric materials and various optical platforms.
    Language English
    Publishing date 2022-12-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13010069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Relationship between Cyber-Ostracism and Adolescents' Non-Suicidal Self-Injury: Mediating Roles of Depression and Experiential Avoidance.

    Ding, Huimin / Zhu, Liyue / Wei, Hua / Geng, Jingyu / Huang, Feng / Lei, Li

    International journal of environmental research and public health

    2022  Volume 19, Issue 19

    Abstract: Based on the experiential avoidance model, the current study aims to test the relationship between cyber-ostracism and adolescents' non-suicidal self-injury and to explore the mediating roles of depression and experiential avoidance. A sample of 1062 ... ...

    Abstract Based on the experiential avoidance model, the current study aims to test the relationship between cyber-ostracism and adolescents' non-suicidal self-injury and to explore the mediating roles of depression and experiential avoidance. A sample of 1062 middle school students completed questionnaires on cyber-ostracism, depression, experiential avoidance, and self-injurious behavior. The results showed that cyber-ostracism, depression, experiential avoidance, and non-suicidal self-injury were positively correlated with each other. After controlling for gender and age, the mediation model test shows that cyber-ostracism was significantly and positively associated with non-suicidal self-injury. Depression and experiential avoidance mediated the relationship between cyber-ostracism and non-suicidal self-injury parallelly and sequentially. This study highlights the potential mechanisms of action between cyber-ostracism and adolescent non-suicidal self-injury and finds that cyber-ostracism is a risk factor for non-suicidal self-injury. This founding suggests that extra attention should be paid to the role of the online environment in addition to the offline environment experiences for the intervention of non-suicidal self-injury.
    MeSH term(s) Adolescent ; Depression/epidemiology ; Humans ; Ostracism ; Risk Factors ; Self-Injurious Behavior/epidemiology ; Surveys and Questionnaires
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph191912236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Impact of Mortality Salience, Negative Emotions and Cultural Values on Suicidal Ideation in COVID-19: A Conditional Process Model.

    Huang, Feng / Li, Sijia / Li, Dongqi / Yang, Meizi / Ding, Huimin / Di, Yazheng / Zhu, Tingshao

    International journal of environmental research and public health

    2022  Volume 19, Issue 15

    Abstract: As suicides incurred by the COVID-19 outbreak keep happening in many countries, researchers have raised concerns that the ongoing pandemic may lead to "a wave of suicides" in society. Suicidal ideation (SI) is a critical factor in conducting suicide ... ...

    Abstract As suicides incurred by the COVID-19 outbreak keep happening in many countries, researchers have raised concerns that the ongoing pandemic may lead to "a wave of suicides" in society. Suicidal ideation (SI) is a critical factor in conducting suicide intervention and also an important indicator for measuring people's mental health. Therefore, it is vital to identify the influencing factors of suicidal ideation and its psychological mechanism during the outbreak. Based on the terror management theory, in the present study we conducted a social media big data analysis to explore the joint effects of mortality salience (MS), negative emotions (NE), and cultural values on suicidal ideation in 337 regions on the Chinese mainland. The findings showed that (1) mortality salience was a positive predictor of suicidal ideation, with negative emotions acting as a mediator; (2) individualism was a positive moderator in the first half-path of the mediation model; (3) collectivism was a negative moderator in the first half-path of the mediation model. Our findings not only expand the application of the terror management theory in suicide intervention but provide some insights into post-pandemic mental healthcare. Timely efforts are needed to provide psychological interventions and counseling on outbreak-caused negative emotions in society. Compared with people living in collectivism-prevailing regions, those living in individualism-prevailing regions may be more vulnerable to mortality salience and negative emotions and need more social attention.
    MeSH term(s) COVID-19/epidemiology ; Emotions ; Humans ; Pandemics ; Suicidal Ideation ; Suicide
    Language English
    Publishing date 2022-07-27
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19159200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Research progress on the modulation mechanism of electroacupuncture for learning and memory impairment after ischemic stroke].

    Zhao, Nan-Nan / Li, Yan-Jie / Qin, He-Wei / Ding, Hui-Min / Hua, Xiao-Qiong / Zhu, Bo-Chao / Wang, Yu-Pu

    Zhongguo zhen jiu = Chinese acupuncture & moxibustion

    2023  Volume 43, Issue 2, Page(s) 239–244

    Abstract: Electroacupuncture may play a role in treatment of learning and memory impairment after ischemic stroke by regulating phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signaling pathway, cyclic adenosine monophosphate (cAMP)-dependent protein ... ...

    Abstract Electroacupuncture may play a role in treatment of learning and memory impairment after ischemic stroke by regulating phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) signaling pathway, cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA)/cAMP response element binding protein (CREB) signaling pathway, nerve growth factor (NGF)/tyrosine kinase-A (TrkA) signaling pathway, Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway, Notch signaling pathway, erythropoietin-producing hepatocyte (Eph)/ephrin signaling pathway. The interactions among these pathways should be further explored in treatment of learning and memory impairment after ischemic stroke.
    MeSH term(s) Humans ; Electroacupuncture ; Ischemic Stroke ; Learning ; Signal Transduction/physiology
    Language Chinese
    Publishing date 2023-02-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 0255-2930
    ISSN 0255-2930
    DOI 10.13703/j.0255-2930.20220304-k0003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Hyperandrogenism drives ovarian inflammation and pyroptosis: A possible pathogenesis of PCOS follicular dysplasia.

    Xiang, Yu / Wang, Hua / Ding, Huimin / Xu, Tianyue / Liu, Xiu / Huang, Zichao / Wu, Honghui / Ge, Hongshan

    International immunopharmacology

    2023  Volume 125, Issue Pt A, Page(s) 111141

    Abstract: Hyperandrogenemia and persistent chronic inflammation, two main striking features of polycystic ovary syndrome (PCOS), have been proven involved in follicular dysgenesis in PCOS. However, the association between hyperandrogenism and inflammation ... ...

    Abstract Hyperandrogenemia and persistent chronic inflammation, two main striking features of polycystic ovary syndrome (PCOS), have been proven involved in follicular dysgenesis in PCOS. However, the association between hyperandrogenism and inflammation activation in PCOS is not fully understood. Excess testosterone(T) induces inflammation and pyroptosis activation in a mouse model of PCOS, leading to ovarian dysfunction and fibrosis. Excessive endoplasmic reticulum (ER) stress is present in ovarian granulosa cells (GCs), testosterone-induced PCOS mouse and cellular models. This study found higher levels of interleukin (IL)-1β, IL-8, IL-17, and IL-18 in the follicular fluid of PCOS patients with hyperandrogenemia undergoing IVF treatment. In addition, pyroptosis in GCs was demonstrated, which was significantly elevated in PCOS patients. To clarify the association of hyperandrogenism, inflammation, and pyroptosis activation in PCOS, dehydroepiandrosterone(DHEA)-treated mouse PCOS model and T-treated KGN cell line were explored for PCOS mechanism. Markers of inflammatory activation and pyroptosis were significantly increased after DHEA treatment in mice and T treatment in KGN cells. In addition, ER stress sensor proteins were increased simultaneously. However, suppression of inflammation by genipin(GP) led to decreased pyroptosis in KGN cells but no variation in ER stress sensor proteins. In contrast, when treated with tauroursodeoxycholic acid(TUDCA) to attenuate ER stress, the markers of inflammatory factors were significantly reduced, accompanied by a reduction in pyroptosis. Our results suggest that persistent hyperandrogenemia of PCOS promotes local inflammatory activation of the ovary, and the imbalanced inflammatory microenvironment leads to pyroptosis of GCs, which is mediated by ER stress activation.
    MeSH term(s) Humans ; Female ; Mice ; Animals ; Polycystic Ovary Syndrome/metabolism ; Polycystic Ovary Syndrome/pathology ; Hyperandrogenism ; Pyroptosis ; Testosterone ; Inflammation ; Dehydroepiandrosterone ; Tumor Microenvironment
    Chemical Substances Testosterone (3XMK78S47O) ; Dehydroepiandrosterone (459AG36T1B)
    Language English
    Publishing date 2023-10-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2023.111141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: MicroRNA-4513 Promotes Gastric Cancer Cell Proliferation and Epithelial-Mesenchymal Transition Through Targeting KAT6B.

    Ding, Huimin / Shi, Yuhua / Liu, Xiaobing / Qiu, Aifeng

    Human gene therapy. Clinical development

    2019  Volume 30, Issue 3, Page(s) 142–148

    Abstract: The purpose of this study was to investigate the expression level of microRNA-4513 (miR-4513) in gastric cancer (GC), and to elucidate the mechanisms underlying its regulation of GC progression. Quantitative real-time PCR (qRT-PCR) was performed to ... ...

    Abstract The purpose of this study was to investigate the expression level of microRNA-4513 (miR-4513) in gastric cancer (GC), and to elucidate the mechanisms underlying its regulation of GC progression. Quantitative real-time PCR (qRT-PCR) was performed to measure the expression level of miR-4513 in GC cells. Transfection efficacy of synthetic miRNAs was examined by qRT-PCR. After synthetic miRNA transfection, cell counting kit-8 assay and transwell invasion assay were conducted to measure biological changes in these groups. The key molecular expression level involved in epithelial-mesenchymal transition (EMT) was analyzed by Western blot. Bioinformatic analysis and Western blot were performed to investigate the connection between miR-4513 and lysine acetyltransferase 6B (KAT6B). qRT-PCR results showed that miR-4513 expression level was upregulated in GC cell lines. Downregulation of miR-4513 expression inhibited GC cell proliferation, invasion, and EMT. KAT6B was validated as a direct target of miR-4513. In addition, KAT6B expression level can be upregulated by miR-4513 inhibitor. Collectively, we showed that miR-4513 is involved in regulating the biological function of GC cells via KAT6B. In addition, miR-4513 may serve as a potential target for the molecular therapy of GC.
    MeSH term(s) Cell Line, Tumor ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Histone Acetyltransferases/metabolism ; Humans ; MicroRNAs ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism
    Chemical Substances MIRN-4513 microRNA, human ; MicroRNAs ; Histone Acetyltransferases (EC 2.3.1.48) ; KAT6B protein, human (EC 2.3.1.48)
    Language English
    Publishing date 2019-07-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2768506-8
    ISSN 2324-8645 ; 2324-8637
    ISSN (online) 2324-8645
    ISSN 2324-8637
    DOI 10.1089/humc.2019.094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Fiber Bragg Grating Wavelength Drift in Long-Term High Temperature Annealing.

    Grobnic, Dan / Hnatovsky, Cyril / Dedyulin, Sergey / Walker, Robert B / Ding, Huimin / Mihailov, Stephen J

    Sensors (Basel, Switzerland)

    2021  Volume 21, Issue 4

    Abstract: High-temperature-resistant fiber Bragg gratings (FBGs) are the main competitors to thermocouples as sensors in applications for high temperature environments defined as being in the 600-1200 °C temperature range. Due to their small size, capacity to be ... ...

    Abstract High-temperature-resistant fiber Bragg gratings (FBGs) are the main competitors to thermocouples as sensors in applications for high temperature environments defined as being in the 600-1200 °C temperature range. Due to their small size, capacity to be multiplexed into high density distributed sensor arrays and survivability in extreme ambient temperatures, they could provide the essential sensing support that is needed in high temperature processes. While capable of providing reliable sensing information in the short term, their long-term functionality is affected by the drift of the characteristic Bragg wavelength or resonance that is used to derive the temperature. A number of physical processes have been proposed as the cause of the high temperature wavelength drift but there is yet no credible description of this process. In this paper we review the literature related to the long-term wavelength drift of FBGs at high temperature and provide our recent results of more than 4000 h of high temperature testing in the 900-1000 °C range. We identify the major components of the high temperature wavelength drift and we propose mechanisms that could be causing them.
    Language English
    Publishing date 2021-02-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s21041454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Hydrazone-linked 2D porphyrinic covalent organic framework photocatalysis for visible light-driven aerobic oxidation of amines to imines.

    Wu, Shujuan / Zhang, Yu-Fei / Ding, Huimin / Li, Xia / Lang, Xianjun

    Journal of colloid and interface science

    2021  Volume 610, Page(s) 446–454

    Abstract: Covalent organic frameworks (COFs) have recently gained rising consideration for visible light photocatalysis. Their property could be accurately established with specific reactions in which the most investigated one turns out to be the aerobic oxidation ...

    Abstract Covalent organic frameworks (COFs) have recently gained rising consideration for visible light photocatalysis. Their property could be accurately established with specific reactions in which the most investigated one turns out to be the aerobic oxidation of amines. In this contribution, a hydrazone-linked 2D (two-dimensional) porphyrinic COF, Por-DETH-COF, was assembled from 5,10,15,20-tetrakis(4-benzaldehyde)porphyrin (p-Por-CHO) and 2,5-diethoxyterephthalohydrazide (DETH) and its photocatalytic activity was duly appraised with the aerobic oxidation of amines. Thereby, the red light-driven selective oxidation of benzyl amines to imines was obtained in very high conversions and selectivities with ambient air as the oxidant. Importantly, the photocatalytic system exhibited remarkable compatibility of functional groups and extensive scope of benzyl amines. Notably, the Por-DETH-COF photocatalyst displayed outstanding recyclability after five successive cycles. This work suggests that 2D COFs could contribute a unique juncture for selective organic transformations by photocatalysis.
    Language English
    Publishing date 2021-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2021.12.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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