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Article: [No title information]

Xie, Ding-Ling / Niu, Hong-Yue

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2023 Volume 43, Issue 11, Page(s) 1226–1228

Title translation	“调神舒筋”法针刺治疗中风后踝关节背屈功能障碍33例.
MeSH term(s)	Humans ; Ankle ; Acupuncture Therapy ; Stroke
Language	Chinese
Publishing date	2023-11-21
Publishing country	China
Document type	Journal Article
ISSN	0255-2930
ISSN	0255-2930
DOI	10.13703/j.0255-2930.20230616-k0002
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Article ; Online: Attitudes, preference and personality in relation to behavioral intention of autonomous vehicle use: An SEM analysis.

Ding, Ling / Yang, Xu

PloS one

2023 Volume 18, Issue 2, Page(s) e0262899

Abstract: Autonomous vehicles (AVs) are entering the market, which will have a great impact on future decision making on mode choice in transportation systems. The aim of this study is to explore the determinants which influence travelers' intentions to use AVs ... ...

Abstract	Autonomous vehicles (AVs) are entering the market, which will have a great impact on future decision making on mode choice in transportation systems. The aim of this study is to explore the determinants which influence travelers' intentions to use AVs based on structural equation modelling (SEM). 310 valid sets of data from an online survey were collected to analyze factors which influence travelers' intentions. Data analyses were conducted using IBM SPSS Statistics 23 and AMOS 23. The results showed that personality and preferences in relation to AVs are the main potential factors that cause travelers' AVs use. Attitudes to modal services also affect intentions to use AVs. Personality has a significant positive effect on both attitude and preferences. The results provide exploratory empirical support for all hypotheses. The research results will help understand travelers' choice motivation from psychological and service perspectives, and provide support for governments and enterprises to improve the management and services of autonomous vehicles.
MeSH term(s)	Intention ; Autonomous Vehicles ; Latent Class Analysis ; Attitude ; Motivation
Language	English
Publishing date	2023-02-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0262899
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Article ; Online: Risk factors of sleep-disordered breathing and poor asthma control in children with asthma.

Tao, Minghui / Zhang, Yanping / Ding, Ling / Peng, Donghong

BMC pediatrics

2024 Volume 24, Issue 1, Page(s) 288

Abstract: Background: Sleep-disordered breathing (SDB) may lead to poor asthma control in children.: Objective: To identify risk factors of SDB in children with asthma and assess its impact on asthma control.: Methods: In this cross-sectional study, we ... ...

Abstract	Background: Sleep-disordered breathing (SDB) may lead to poor asthma control in children. Objective: To identify risk factors of SDB in children with asthma and assess its impact on asthma control. Methods: In this cross-sectional study, we collected data of outpatients with asthma at the Children's Hospital of Chongqing Medical University from June 2020 to August 2021. The Pediatric Sleep Questionnaire-Sleep-Related Breathing Disorder and the age-appropriate asthma control tests Childhood Asthma Control Test and Test for Respiratory and Asthma Control in Kids were completed. Results: We enrolled 397 children with a male-to-female ratio of 1.7:1 and a mean age of 5.70 ± 2.53 years. The prevalence of SDB was 21.6%. Allergic rhinitis (odds ratio OR = 3.316), chronic tonsillitis (OR = 2.246), gastroesophageal reflux (OR = 7.518), adenoid hypertrophy (OR = 3.479), recurrent respiratory infections (OR = 2.195), and a family history of snoring (OR = 2.048) were risk factors for the development of combined SDB in children with asthma (p < 0.05). Asthma was poorly controlled in 19.6% of the children. SDB (OR = 2.391) and irregular medication use (OR = 2.571) were risk factors for poor asthma control (p < 0.05). Conclusions: Allergic rhinitis, chronic tonsillitis, gastroesophageal reflux, adenoid hypertrophy, recurrent respiratory infections, and a family history of snoring were independent risk factors for the development of SDB in children with asthma. SDB and irregular medication use were independent risk factors for poor asthma control.
MeSH term(s)	Humans ; Asthma/epidemiology ; Asthma/complications ; Male ; Female ; Risk Factors ; Cross-Sectional Studies ; Sleep Apnea Syndromes/epidemiology ; Sleep Apnea Syndromes/complications ; Child ; Child, Preschool ; Rhinitis, Allergic/complications ; Rhinitis, Allergic/epidemiology ; Prevalence ; China/epidemiology ; Tonsillitis/complications ; Tonsillitis/epidemiology ; Snoring/epidemiology ; Adenoids/pathology ; Respiratory Tract Infections/epidemiology ; Respiratory Tract Infections/complications
Language	English
Publishing date	2024-04-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-024-04762-7
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Article ; Online: Single cell RNA-sequencing data generated from mouse adipose tissue during the development of obesity.

Lu, Zhimin / Ding, Ling / Tian, Xuewen / Wang, Qinglu

Data in brief

2024 Volume 53, Page(s) 110119

Abstract: In recent years, the number of obesity has increased rapidly around the world, and it has become a major public health problem endangering global health [1]. Obesity is caused by excessive calorie intake over a long period of time, and high-fat diet (HFD) ...

Abstract	In recent years, the number of obesity has increased rapidly around the world, and it has become a major public health problem endangering global health [1]. Obesity is caused by excessive calorie intake over a long period of time, and high-fat diet (HFD) is one of the important predisposing factors [2], [3], [4]. Adipose tissue (AT) is an important immune and endocrine organ in the body, and plays an important role in the body [5]. Obesity leads to AT dysfunction, AT dilation and cell hypertrophy. Dysfunctional fat cells are the main source of pro-inflammatory cytokines, which aggravate low-grade systemic inflammation and further promote the development of obesity-related diseases [6], [7], [8]. However, whether AT releases pro-inflammatory cytokines in the early stages of obesity development remains unknown. The AT microenvironment is composed of a variety of cells, including fat cells, immune cells, fibroblasts, and endothelial cells. The immune microenvironment (TIME) and its metabolic imbalance can lead to the secretion or regulation of related hormones, which causes inflammation AT [9]. TIME is very important for maintaining AT homeostasis, which is crucial for the occurrence of obesity [10,11]. This data use single-cell RNA sequencing (sNuc-Seq) to analyze the characteristics of TIME changes in the mouse epididymal adipose tissue during the development of obesity, and the changes of cell types and genes in the tissue.
Language	English
Publishing date	2024-02-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2786545-9
ISSN	2352-3409 ; 2352-3409
ISSN (online)	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2024.110119
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Article ; Online: Investigation on acoustic emission characteristics of fault stick-slip under different lateral pressures.

Ding, Ling / Zhao, Yangfeng / Pan, Yishan / Fan, Yi

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6718

Abstract: To explore the effect of different stress environments on fault-slip rockbursts. Bidirectional shear friction experiments with different lateral pressures were conducted on precracked syenogranites buried at 800 m. The macroscopic statistical parameters ( ...

Abstract	To explore the effect of different stress environments on fault-slip rockbursts. Bidirectional shear friction experiments with different lateral pressures were conducted on precracked syenogranites buried at 800 m. The macroscopic statistical parameters (cumulative number of AE events, magnitude and b value) and local characteristic parameters (amplitude and dominant frequency) of acoustic emission during the stick-slip process under different lateral pressures were investigated. In addition, based on fractal theory, the nonlinear characteristics of AE spectrum were analyzed. On this basis, the microscopic mechanism of fault stick-slip was discussed. The results show that the lateral pressure influences the friction strength of the fault and stick-slip motion characteristics. With increasing lateral pressure, the proportion of transgranular shear fractures increases, which leads to an increase of cumulative number of AE events and magnitude. The periodic decrease in the b value is more significant at high lateral pressure. There is a good correlation between a high-magnitude AE event and a stress drop. The AE frequency with phased response characteristics can be used to effectively identify the evolution of fault stick-slip instability at the laboratory scale. A sharp increase in the amplitude of the dominant frequency can be regarded as one of the precursory features of fault stick-slip instability. The AE frequency spectra have multifractal characteristics, that differ among the different stages. The maximum multifractal dimension and spectral width can reflect the difference in energy released during fault stick-slip motion.
Language	English
Publishing date	2024-03-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57076-0
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Article ; Online: Identification of potential core genes in pseudoexfoliation using bioinformatics analysis and retrospective analysis of 84 patients with this disease.

Liu, Xiaodi / Qin, Yanli / Wei, Bixia / Ding, Ling

International ophthalmology

2024 Volume 44, Issue 1, Page(s) 161

Abstract: Background: Pseudoexfoliation (XFS) is a common cause of glaucoma in nowadays. Because of XFS causing irreversible blindness secondary to glaucoma (XFG), this study aims to identify the current prevalence of XFS among Xinjiang Province of China, and ... ...

Abstract	Background: Pseudoexfoliation (XFS) is a common cause of glaucoma in nowadays. Because of XFS causing irreversible blindness secondary to glaucoma (XFG), this study aims to identify the current prevalence of XFS among Xinjiang Province of China, and identify the hub genes involved in XFS. Methods: A retrospective chart review was conducted from 2007 to 2019 for patients aged 50 and older. All patients with XFS or XFG diagnosed by slit lamp exam were identified through chart review. Results: Of the 84 patient charts available for review, 50% of the patients identified as male, with a mean age of 67 years. The top ten genes evaluated by connectivity degree in the PPI network were identified. The results showed that Tyrobp was the most outstanding gene, followed by Ptprc, Fcgr3, Itgb2, Emr1, Cd68, Syk, Fcerlg, Hck, and Lyz2. All of these hub genes were downregulated in XFS. Conclusion: Our findings show a considerably biomarkers of XFS for diagnosis and treatment.
MeSH term(s)	Humans ; Male ; Middle Aged ; Aged ; Exfoliation Syndrome/epidemiology ; Retrospective Studies ; Glaucoma/complications ; China/epidemiology
Language	English
Publishing date	2024-03-27
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-024-03092-y
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Article ; Online: Role of non‑coding RNAs in UV‑induced radiation effects (Review).

Liang, Xiaofei / Zhang, Chao / Shen, Lijuan / Ding, Ling / Guo, Haipeng

Experimental and therapeutic medicine

2024 Volume 27, Issue 6, Page(s) 262

Abstract: Ultraviolet (UV) is divided into UVA (long-wave, 320-400 nm), UVB (middle-wave, 280-320 nm) and UVC (short-wave, 100-280 nm) based on wavelength. UV radiation (UVR) from sunlight (UVA + UVB) is a major cause of skin photodamage including skin ... ...

Abstract	Ultraviolet (UV) is divided into UVA (long-wave, 320-400 nm), UVB (middle-wave, 280-320 nm) and UVC (short-wave, 100-280 nm) based on wavelength. UV radiation (UVR) from sunlight (UVA + UVB) is a major cause of skin photodamage including skin inflammation, aging and pigmentation. Accidental exposure to UVC burns the skin and induces skin cancer. In addition to the skin, UV radiation can also impair visual function. Non-coding RNAs (ncRNAs) are a class of functional RNAs that do not have coding activity but can control cellular processes at the post-transcriptional level, including microRNA (miRNA), long non-coding RNA (lncRNA) and circulatory RNA (circRNA). Through a review of the literature, it was determined that UVR can affect the expression of various ncRNAs, and that this regulation may be wavelength specific. Functionally, ncRNAs participate in the regulation of photodamage through various pathways and play pathogenic or protective regulatory roles. In addition, ncRNAs that are upregulated or downregulated by UVR can serve as biomarkers for UV-induced diseases, aiding in diagnosis and prognosis assessment. Therapeutic strategies targeting ncRNAs, including the use of natural drugs and their extracts, have shown protective effects against UV-induced photodamage. In the present review, an extensive summarization of previous studies was performed and the role and mechanism of ncRNAs in UV-induced radiation effects was reviewed to aid in the diagnosis and treatment of UV-related diseases.
Language	English
Publishing date	2024-04-23
Publishing country	Greece
Document type	Journal Article ; Review
ZDB-ID	2683844-8
ISSN	1792-1015 ; 1792-0981
ISSN (online)	1792-1015
ISSN	1792-0981
DOI	10.3892/etm.2024.12550
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Article ; Online: Shared molecular signatures between coronavirus infection and neurodegenerative diseases provide targets for broad-spectrum drug development.

Deng, Li / Ding, Ling / Duan, Xianlai / Peng, Yousong

Scientific reports

2023 Volume 13, Issue 1, Page(s) 5457

Abstract: Growing evidences have suggested the association between coronavirus infection and neurodegenerative diseases. However, the molecular mechanism behind the association is complex and remains to be clarified. This study integrated human genes involved in ... ...

Abstract	Growing evidences have suggested the association between coronavirus infection and neurodegenerative diseases. However, the molecular mechanism behind the association is complex and remains to be clarified. This study integrated human genes involved in infections of three coronaviruses including SARS-CoV-2, SARS-CoV and MERS-CoV from multi-omics data, and investigated the shared genes and molecular functions between coronavirus infection and two neurodegenerative diseases, namely Alzheimer's Disease (AD) and Parkinson's Disease (PD). Seven genes including HSP90AA1, ALDH2, CAV1, COMT, MTOR, IGF2R and HSPA1A, and several inflammation and stress response-related molecular functions such as MAPK signaling pathway, NF-kappa B signaling pathway, responses to oxidative or chemical stress were common to both coronavirus infection and neurodegenerative diseases. These genes were further found to interact with more than 20 other viruses. Finally, drugs targeting these genes were identified. The study would not only help clarify the molecular mechanism behind the association between coronavirus infection and neurodegenerative diseases, but also provide novel targets for the development of broad-spectrum drugs against both coronaviruses and neurodegenerative diseases.
MeSH term(s)	Humans ; COVID-19/genetics ; SARS-CoV-2 ; Neurodegenerative Diseases/drug therapy ; Neurodegenerative Diseases/genetics ; Middle East Respiratory Syndrome Coronavirus ; Drug Development ; Aldehyde Dehydrogenase, Mitochondrial
Chemical Substances	ALDH2 protein, human (EC 1.2.1.3) ; Aldehyde Dehydrogenase, Mitochondrial (EC 1.2.1.3)
Language	English
Publishing date	2023-04-04
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-29778-4
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Article ; Online: Serum cross-linked N-telopeptide of type I collagen as a potential diagnostic marker for bone metastasis in lung cancer: An updated meta-analysis.

Wang, Haiyan / Hong, Mingsheng / Ding, Ling / Song, Baona

Thoracic cancer

2023 Volume 14, Issue 9, Page(s) 787–793

Abstract: Objective: To investigate the clinical value of serum type I collagen cross-linked amino terminal peptide (NTx) for the diagnosis of bone metastasis in lung cancer patients by evidence-based medicine.: Methods: Diagnostic studies relevant to NTx as a ...

Abstract	Objective: To investigate the clinical value of serum type I collagen cross-linked amino terminal peptide (NTx) for the diagnosis of bone metastasis in lung cancer patients by evidence-based medicine. Methods: Diagnostic studies relevant to NTx as a serum marker for the diagnosis of bone metastasis in lung cancer patients included in the China National Knowledge Infrastructure, Wanfang, PubMed, Embase, and VIP database from the establishment of the databases to November 2022 were retrieved. Meta-analysis was conducted with Stata 16.0 software to calculate the combined sensitivity (SEN), specificity (SPN), positive likelihood ratio (+LR), negative likelihood ratio (-LR), diagnostic odds ratio (DOR), and its 95% confidence interval (CI). The total subject working characteristic curve (summary receiver operating characteristic (SROC) curve) was drawn, and the area under the curve was calculated to evaluate its diagnostic value. Results: A total of 1742 patients with lung cancer were included in 14 articles. Meta-analysis showed heterogeneity among the studies. The results of random-effect model analysis demonstrated that the combined SEN, SPN, +LR, -LR, and DOR were 0.76 (95% CI 0.66-0.83), 0.80 (95% CI 0.74-0.85), 3.80 (95% CI 2.90-4.80), 0.30 (95% CI 0.22-0.42), and 12 (95% CI 8-19), respectively, and the area under SROC was 0.85. Conclusion: Serum NTx has a high clinical value in the diagnosis of bone metastasis in lung cancer patients and can be used as an effective complementary means for imaging diagnosis of bone metastasis in lung cancer patients.
MeSH term(s)	Humans ; Collagen Type I ; Lung Neoplasms/pathology ; Peptides ; ROC Curve ; Bone Neoplasms/diagnosis ; Bone Neoplasms/secondary ; Sensitivity and Specificity
Chemical Substances	collagen type I trimeric cross-linked peptide ; Collagen Type I ; Peptides
Language	English
Publishing date	2023-01-30
Publishing country	Singapore
Document type	Meta-Analysis ; Journal Article
ZDB-ID	2625856-0
ISSN	1759-7714 ; 1759-7706
ISSN (online)	1759-7714
ISSN	1759-7706
DOI	10.1111/1759-7714.14808
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Article ; Online: Electrode-Modiolus Distance Affects Speech Perception for Lateral Wall Electrodes.

Ding, Ling / Zhang, Luguang / Li, Jing / Lin, Tao

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

2023 Volume 44, Issue 10, Page(s) e702–e709

Abstract: Objectives: The goal of this study was to use cone-beam computed tomography to locate the electrode-modiolus distance (EMD) and correlate this with speech perception in cochlear implant (CI) recipients of the 31.5-mm lateral wall (LW) electrode arrays.!# ...

Abstract	Objectives: The goal of this study was to use cone-beam computed tomography to locate the electrode-modiolus distance (EMD) and correlate this with speech perception in cochlear implant (CI) recipients of the 31.5-mm lateral wall (LW) electrode arrays. Study design: Retrospective review. Patients: Forty-five child CI recipients with prelingual profound sensorineural hearing loss of inserted 31.5-mm LW arrays listening with a CI-alone device. Interventions: Stepwise forward multiple linear regression was performed to control and reduce the variability in implant performance to determine whether EMD affects speech perception. Main outcome measures: Electrode location (angular insertion depth [AID], EMD), together with the electrode impedance (EI), surgical approach, sex, CI age, and preimplant hearing aid usage were estimated as independent variables. The dependent variables were the Meaningful Use of Speech Scale (MUSS) and parents' evaluation of children's aural/oral performance (PEACH) assessed with the CI alone at 12 months postactivation. Results: EMD and CI age were predictive variables for PEACH/MUSS. A negative correlation was found between AID and EMD (r = -0.56, p < 0.01), whereas EMD had a moderately positive correlation with EI (r = 0.32, p < 0.01). Conclusions: The best "location-related" predictor of postoperative speech perception was EMD with a 31.5-mm array among CI-alone users.
MeSH term(s)	Child ; Humans ; Speech Perception/physiology ; Treatment Outcome ; Cochlea/surgery ; Cochlear Implantation/methods ; Cochlear Implants
Language	English
Publishing date	2023-09-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2036790-9
ISSN	1537-4505 ; 1531-7129
ISSN (online)	1537-4505
ISSN	1531-7129
DOI	10.1097/MAO.0000000000004019
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