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  1. Article ; Online: Laboratory information management system for biosafety laboratory

    Dingzhong Sun / Linhuan Wu / Guomei Fan

    Journal of Biosafety and Biosecurity, Vol 3, Iss 1, Pp 28-

    Safety and efficiency

    2021  Volume 34

    Abstract: Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work, which is the major concern of biosafety laboratories ( ... ...

    Abstract Laboratory information management system (LIMS) has been widely used to facilitate laboratory activities. However, the current LIMSs do not contain functions to improve the safety of laboratory work, which is the major concern of biosafety laboratories (BSLs). With tons of biosafety information that need to be managed and an increasing number of biosafety-related research projects under way, it is worthy of expanding the current framework of LIMS and building a system that is more suitable for BSL usage. Such a system should carefully trade off between the safety and efficiency of regular lab activities, allowing the laboratory staff to conduct their research as free as possible while ensuring their and the environment’s safety. In order to achieve this goal, the information on the research contents, laboratory personnel, experimental materials and experimental equipment need to be well collected and fully utilized by a centralized system and its databases.
    Keywords Laboratory information management system ; Biosafety ; Biological research laboratory ; Laboratory safety ; Workflow management ; Biology (General) ; QH301-705.5
    Subject code 020
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher KeAi Communications Co., Ltd.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: IPGA

    Dongmei Liu / Yifei Zhang / Guomei Fan / Dingzhong Sun / Xingjiao Zhang / Zhengfei Yu / Jinfeng Wang / Linhuan Wu / Wenyu Shi / Juncai Ma

    iMeta, Vol 1, Iss 4, Pp n/a-n/a (2022)

    A handy integrated prokaryotes genome and pan‐genome analysis web service

    2022  

    Abstract: Abstract Pan‐genomics is one of the most powerful means to study genomic variation and obtain a sketch of genes within a defined clade of species. Though there are a lot of computational tools to achieve this, an integrated framework to evaluate their ... ...

    Abstract Abstract Pan‐genomics is one of the most powerful means to study genomic variation and obtain a sketch of genes within a defined clade of species. Though there are a lot of computational tools to achieve this, an integrated framework to evaluate their performance and offer the best choice to users has never been achieved. To ease the process of large‐scale prokaryotic genome analysis, we introduce Integrated Prokaryotes Genome and pan‐genome Analysis (IPGA), a one‐stop web service to analyze, compare, and visualize pan‐genome as well as individual genomes, that rids users of installing any specific tools. IPGA features a scoring system that helps users to evaluate the reliability of pan‐genome profiles generated by different packages. Thus, IPGA can help users ascertain the profiling method that is most suitable for their data set for the following analysis. In addition, IPGA integrates several downstream comparative analysis and genome analysis modules to make users achieve diverse targets.
    Keywords comparative genomics ; pan‐genome ; web service ; Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 004
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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