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  1. Article ; Online: Prevalence of malaria-helminth co-infections among children living in a setting of high coverage of standard interventions for malaria and helminths: Two population-based studies in Senegal.

    Afolabi, Muhammed O / Sow, Doudou / Mbaye, Ibrahima / Diouf, Marie Pierre / Loum, Mor Absa / Fall, Elhadji Babacar / Seck, Amadou / Manga, Isaac A / Cissé, Cheikh / Camara, Baba / Diouf, Awa / Gaye, Ndéye Aida / Colle Lo, Aminata / Greenwood, Brian / Ndiaye, Jean Louis A

    Frontiers in public health

    2023  Volume 11, Page(s) 1087044

    Abstract: Background: Concurrent infections of : Methods: We enrolled 910 children aged 1-14 years from Saraya and Diourbel districts of Senegal in June and November 2021, respectively. We collected finger-prick blood samples from the children for malaria ... ...

    Abstract Background: Concurrent infections of
    Methods: We enrolled 910 children aged 1-14 years from Saraya and Diourbel districts of Senegal in June and November 2021, respectively. We collected finger-prick blood samples from the children for malaria parasite detection using microscopy and PCR methods. Stool samples were also collected and Kato-Katz and PCR methods were used to detect STH and
    Results: The overall prevalence of polyparasitism with
    Conclusions: The prevalence of malaria-helminth co-infection is low in two districts in Senegal, possibly due to sustained implementation of effective control measures for malaria and NTDs. These findings could help to develop and implement strategies that would lead to elimination of malaria and helminths in the study areas.
    MeSH term(s) Male ; Animals ; Female ; Humans ; Child ; Child, Preschool ; Adolescent ; Coinfection/epidemiology ; Prevalence ; Senegal/epidemiology ; Prospective Studies ; Helminthiasis/epidemiology ; Helminths ; Malaria/epidemiology ; Malaria, Falciparum/epidemiology ; Malaria, Falciparum/parasitology ; Soil/parasitology
    Chemical Substances Soil
    Language English
    Publishing date 2023-03-02
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1087044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Feasibility and safety of integrating mass drug administration for helminth control with seasonal malaria chemoprevention among Senegalese children: a randomized controlled, observer-blind trial.

    Afolabi, Muhammed O / Sow, Doudou / Agbla, Schadrac C / Fall, El Hadji Babacar / Sall, Fatimata Bintou / Seck, Amadou / Manga, Isaac Akhénaton / Mbaye, Ibrahima Marietou / Loum, Mor Absa / Camara, Baba / Niang, Diatou / Gueye, Babacar / Sene, Doudou / Kane, Ndéye M'backé / Diop, Boubacar / Diouf, Awa / Gaye, Ndéye Aida / Diouf, Marie Pierre / Lo, Aminata Colle /
    Greenwood, Brian / Ndiaye, Jean Louis A

    Malaria journal

    2023  Volume 22, Issue 1, Page(s) 348

    Abstract: Background: The overlap in the epidemiology of malaria and helminths has been identified as a potential area to exploit for the development of an integrated control strategy that may help to achieve elimination of malaria and helminths. A randomized, ... ...

    Abstract Background: The overlap in the epidemiology of malaria and helminths has been identified as a potential area to exploit for the development of an integrated control strategy that may help to achieve elimination of malaria and helminths. A randomized, controlled, observer-blind trial was conducted to assess the feasibility and safety of combining mass drug administration (MDA) for schistosomiasis and soil transmitted helminths (STH) with seasonal malaria chemoprevention (SMC) among children living in Senegal.
    Methods: Female and male children aged 1-14 years were randomized 1:1:1, to receive Vitamin A and Zinc on Day 0, followed by SMC drugs (sulfadoxine-pyrimethamine and amodiaquine) on Days 1-3 (control group); or praziquantel and Vitamin A on Day 0, followed by SMC drugs on Days 1-3 (treatment group 1); or albendazole and praziquantel on Day 0, followed by SMC drugs on Days 1-3 (treatment group 2). Safety assessment was performed by collecting adverse events from all children for six subsequent days following administration of the study drugs. Pre- and post-intervention, blood samples were collected for determination of haemoglobin concentration, malaria microscopy, and PCR assays. Stool samples were analyzed using Kato-Katz, Merthiolate-iodine-formalin and PCR methods. Urine filtration, PCR and circulating cathodic antigen tests were also performed.
    Results: From 9 to 22 June 2022, 627 children aged 1-14 years were randomized into the three groups described above. Mild, transient vomiting was observed in 12.6% (26/206) of children in treatment group 2, in 10.6% (22/207) in group 1, and in 4.2% (9/214) in the control group (p = 0.005). Pre-intervention, the geometric mean value of Plasmodium falciparum parasite density was highest among children who received albendazole, praziquantel with SMC drugs. Post-intervention, the parasite density was highest among children who received SMC drugs only. Children who received praziquantel and SMC drugs had a lower risk of developing severe anaemia than their counterparts who received SMC drugs alone (OR = 0.81, 95% CI 0.13-5.00, p = 0.63).
    Conclusions: Integration of MDA for helminths with SMC drugs was safe and feasible among Senegalese children. These findings support further evaluation of the integrated control model.
    Trial registration: The study is registered at Clinical Trial.gov NCT05354258.
    MeSH term(s) Animals ; Humans ; Child ; Male ; Female ; Antimalarials/adverse effects ; Praziquantel/adverse effects ; Albendazole/adverse effects ; Mass Drug Administration ; Seasons ; Feasibility Studies ; Vitamin A/therapeutic use ; Malaria/epidemiology ; Helminths ; Chemoprevention/adverse effects ; Chemoprevention/methods
    Chemical Substances Antimalarials ; Praziquantel (6490C9U457) ; Albendazole (F4216019LN) ; Vitamin A (11103-57-4)
    Language English
    Publishing date 2023-11-13
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2091229-8
    ISSN 1475-2875 ; 1475-2875
    ISSN (online) 1475-2875
    ISSN 1475-2875
    DOI 10.1186/s12936-023-04784-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Farmers' perceptions of climate change and agricultural adaptation strategies in rural Sahel.

    Mertz, Ole / Mbow, Cheikh / Reenberg, Anette / Diouf, Awa

    Environmental management

    2009  Volume 43, Issue 5, Page(s) 804–816

    Abstract: Farmers in the Sahel have always been facing climatic variability at intra- and inter-annual and decadal time scales. While coping and adaptation strategies have traditionally included crop diversification, mobility, livelihood diversification, and ... ...

    Abstract Farmers in the Sahel have always been facing climatic variability at intra- and inter-annual and decadal time scales. While coping and adaptation strategies have traditionally included crop diversification, mobility, livelihood diversification, and migration, singling out climate as a direct driver of changes is not so simple. Using focus group interviews and a household survey, this study analyzes the perceptions of climate change and the strategies for coping and adaptation by sedentary farmers in the savanna zone of central Senegal. Households are aware of climate variability and identify wind and occasional excess rainfall as the most destructive climate factors. Households attribute poor livestock health, reduced crop yields and a range of other problems to climate factors, especially wind. However, when questions on land use and livelihood change are not asked directly in a climate context, households and groups assign economic, political, and social rather than climate factors as the main reasons for change. It is concluded that the communities studied have a high awareness of climate issues, but climatic narratives are likely to influence responses when questions mention climate. Change in land use and livelihood strategies is driven by adaptation to a range of factors of which climate appears not to be the most important. Implications for policy-making on agricultural and economic development will be to focus on providing flexible options rather than specific solutions to uncertain climate.
    MeSH term(s) Agriculture/economics ; Agriculture/methods ; Burkina Faso ; Climate ; Greenhouse Effect ; Humans ; Public Opinion
    Language English
    Publishing date 2009-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-008-9197-0
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  4. Article: Farmers' Perceptions of Climate Change and Agricultural Adaptation Strategies in Rural Sahel

    Mertz, Ole / Mbow, Cheikh / Reenberg, Anette / Diouf, Awa

    Environmental management. 2009 May, v. 43, no. 5

    2009  

    Abstract: Farmers in the Sahel have always been facing climatic variability at intra- and inter-annual and decadal time scales. While coping and adaptation strategies have traditionally included crop diversification, mobility, livelihood diversification, and ... ...

    Abstract Farmers in the Sahel have always been facing climatic variability at intra- and inter-annual and decadal time scales. While coping and adaptation strategies have traditionally included crop diversification, mobility, livelihood diversification, and migration, singling out climate as a direct driver of changes is not so simple. Using focus group interviews and a household survey, this study analyzes the perceptions of climate change and the strategies for coping and adaptation by sedentary farmers in the savanna zone of central Senegal. Households are aware of climate variability and identify wind and occasional excess rainfall as the most destructive climate factors. Households attribute poor livestock health, reduced crop yields and a range of other problems to climate factors, especially wind. However, when questions on land use and livelihood change are not asked directly in a climate context, households and groups assign economic, political, and social rather than climate factors as the main reasons for change. It is concluded that the communities studied have a high awareness of climate issues, but climatic narratives are likely to influence responses when questions mention climate. Change in land use and livelihood strategies is driven by adaptation to a range of factors of which climate appears not to be the most important. Implications for policy-making on agricultural and economic development will be to focus on providing flexible options rather than specific solutions to uncertain climate.
    Keywords Sahel ; climate change ; climatic factors ; coping strategies ; crop yield ; economic development ; farmers ; households ; interviews ; land use change ; livelihood ; livestock ; rain ; savannas ; surveys ; wind ; Senegal
    Language English
    Dates of publication 2009-05
    Size p. 804-816.
    Publisher Springer-Verlag
    Publishing place New York
    Document type Article
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-008-9197-0
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  5. Article: Climate variability and environmental stress in the Sudan-Sahel zone of West Africa.

    Mertz, Ole / D'haen, Sarah / Maiga, Abdou / Moussa, Ibrahim Bouzou / Barbier, Bruno / Diouf, Awa / Diallo, Drissa / Da, Evariste Dapola / Dabi, Daniel

    Ambio

    2012  Volume 41, Issue 4, Page(s) 380–392

    Abstract: Environmental change in the Sudan-Sahel region of West Africa (SSWA) has been much debated since the droughts of the 1970s. In this article we assess climate variability and environmental stress in the region. Households in Senegal, Mali, Burkina Faso, ... ...

    Abstract Environmental change in the Sudan-Sahel region of West Africa (SSWA) has been much debated since the droughts of the 1970s. In this article we assess climate variability and environmental stress in the region. Households in Senegal, Mali, Burkina Faso, Niger, and Nigeria were asked about climatic changes and their perceptions were compared across north-south and west-east rainfall gradients. More than 80% of all households found that rainfall had decreased, especially in the wettest areas. Increases in wind speeds and temperature were perceived by an overall 60-80% of households. Contrary to household perceptions, observed rainfall patterns showed an increasing trend over the past 20 years. However, August rainfall declined, and could therefore potentially explain the contrasting negative household perceptions of rainfall trends. Most households reported degradation of soils, water resources, vegetation, and fauna, but more so in the 500-900 mm zones. Adaptation measures to counter environmental degradation included use of manure, reforestation, soil and water conservation, and protection of fauna and vegetation. The results raise concerns for future environmental management in the region, especially in the 500-900 mm zones and the western part of SSWA.
    MeSH term(s) Africa South of the Sahara ; Climate Change ; Data Collection ; Ecosystem ; Environmental Monitoring ; Family Characteristics ; Geography ; Humans ; Rain ; Time Factors
    Language English
    Publishing date 2012-01-24
    Publishing country Sweden
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120759-3
    ISSN 1654-7209 ; 0044-7447
    ISSN (online) 1654-7209
    ISSN 0044-7447
    DOI 10.1007/s13280-011-0231-8
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  6. Article: Climate Variability and Environmental Stress in the Sudan-Sahel Zone of West Africa

    Mertz, Ole / D’haen, Sarah / Maiga, Abdou / Moussa, Ibrahim Bouzou / Barbier, Bruno / Diouf, Awa / Diallo, Drissa / Da, Evariste Dapola / Dabi, Daniel

    Ambio a journal of the human environment. 2012 June, v. 41, no. 4

    2012  

    Abstract: Environmental change in the Sudan-Sahel region of West Africa (SSWA) has been much debated since the droughts of the 1970s. In this article we assess climate variability and environmental stress in the region. Households in Senegal, Mali, Burkina Faso, ... ...

    Abstract Environmental change in the Sudan-Sahel region of West Africa (SSWA) has been much debated since the droughts of the 1970s. In this article we assess climate variability and environmental stress in the region. Households in Senegal, Mali, Burkina Faso, Niger, and Nigeria were asked about climatic changes and their perceptions were compared across north–south and west–east rainfall gradients. More than 80% of all households found that rainfall had decreased, especially in the wettest areas. Increases in wind speeds and temperature were perceived by an overall 60–80% of households. Contrary to household perceptions, observed rainfall patterns showed an increasing trend over the past 20 years. However, August rainfall declined, and could therefore potentially explain the contrasting negative household perceptions of rainfall trends. Most households reported degradation of soils, water resources, vegetation, and fauna, but more so in the 500–900 mm zones. Adaptation measures to counter environmental degradation included use of manure, reforestation, soil and water conservation, and protection of fauna and vegetation. The results raise concerns for future environmental management in the region, especially in the 500–900 mm zones and the western part of SSWA.
    Keywords climate ; climate change ; environmental degradation ; environmental management ; fauna ; households ; rain ; reforestation ; temperature ; vegetation ; water conservation ; water resources ; wind ; Burkina Faso ; Mali ; Niger ; Nigeria ; Senegal
    Language English
    Dates of publication 2012-06
    Size p. 380-392.
    Publishing place Springer-Verlag
    Document type Article
    ZDB-ID 120759-3
    ISSN 1654-7209 ; 0044-7447
    ISSN (online) 1654-7209
    ISSN 0044-7447
    DOI 10.1007/s13280-011-0231-8
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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