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  1. Article ; Online: Infant mortality due to congenital malformations in the Autonomous City of Buenos Aires (1998-2015): Spatial, temporal analysis and relation to the socioeconomic status.

    Bronberg, Rubén A / Dipierri, José E

    Archivos argentinos de pediatria

    2019  Volume 117, Issue 3, Page(s) 171–178

    Abstract: Introduction: In Argentina, congenital malformations (CM) account for the second cause of death among infants younger than 1 year.: Objective: To analyze spatial and temporal variation in infant mortality due to CM in the Autonomous City of Buenos ... ...

    Title translation Mortalidad infantil por malformaciones congénitas en la Ciudad Autónoma de Buenos Aires (1998-2015): Análisis espacial, temporal y relación con la condición socioeconómica.
    Abstract Introduction: In Argentina, congenital malformations (CM) account for the second cause of death among infants younger than 1 year.
    Objective: To analyze spatial and temporal variation in infant mortality due to CM in the Autonomous City of Buenos Aires and its relation to a socioeconomic development indicator.
    Materials and methods: Births and deaths among infants younger than 1 year were coded using the International Classification of Diseases (ICD-10); data were provided by the Ministry of Health. Geographical areas: northern, central and southern. The nervous system, the cardiovascular system, chromosomal abnormalities, and 28 specific malformations were evaluated. Infant mortality rate due to CM (IMR-CM) and the percentage of deaths from CM (PD-CM) were estimated in 3 periods (1998-2003, 2004-2009, 2010-2015). Secular trend and risk of death were estimated using the Poisson regression model. A socioeconomic development indicator correlated to the IMR-CM and the PD-CM was obtained by means of a principal component analysis.
    Results: The IMR-CM and the PD-CM had, respectively, a negative and positive secular trend with statistical significance, and exhibited a differentiation by areas. The IMR-CM values decreased for central nervous system and cardiovascular system malformations, and increased for chromosomal abnormalities (p < 0.05). The IMR-CM and the PD-CM were positively and negatively correlated, respectively, with the socioeconomic indicator (p < 0.05).
    Conclusion: Infant mortality indicators due to CM in the Autonomous City of Buenos Aires are spatially and temporally heterogeneous, and are related to the socioeconomic characteristics of the areas.
    MeSH term(s) Argentina/epidemiology ; Cause of Death ; Congenital Abnormalities/mortality ; Humans ; Infant ; Infant Mortality/trends ; Infant, Newborn ; Socioeconomic Factors ; Spatio-Temporal Analysis
    Language Spanish
    Publishing date 2019-05-06
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2019.eng.171
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  2. Article ; Online: Birth weight in the Northwest region of Argentina. Comparison with a national reference and an international standard.

    Revollo, Gabriela B / Dipierri, José E / Díaz, María Del Pilar / Alfaro Gómez, Emma L

    Archivos argentinos de pediatria

    2023  Volume 122, Issue 2, Page(s) e202310051

    Abstract: Introduction. Size at birth is subject to genetic and environmental influences; altitude is highly influential. Birth weight (BW) is the most widely used indicator to assess size at birth; different standards and references are available. Due to the ... ...

    Title translation Peso al nacer en el noroeste argentino. Comparación conuna referencia nacional y un estándar internacional.
    Abstract Introduction. Size at birth is subject to genetic and environmental influences; altitude is highly influential. Birth weight (BW) is the most widely used indicator to assess size at birth; different standards and references are available. Due to the variability in BW distribution in relation to altitude in the province of Jujuy (Argentina), the purpose of this study is to analyze the percentile distribution of BW in the highlands (HL) and the lowlands (LL) of Jujuy based on gestational age (GA) and sex and compare it with a national reference and the INTERGROWTH-21st (IG-21) international standard. Population and methods. The records of 78 524 live births in Jujuy in the 2009-2014 period were analyzed. Using the LMS method, the 3rd, 10th, 50th, 90th, and 97th percentiles of BW/GA by sex were estimated for the HL (≥ 2000 MASL), the LL (< 2000 MASL), and the total for Jujuy, and compared with the Argentine population reference by Urquía and the IG-21 standard using growth charts. The statistical significance was established using the Wilcoxon test. Results. BW in Jujuy showed a heterogeneous distribution, with statistically significant differences (p < 0.05) between the LL and the HL. When compared with the national reference and the IG-21 standard, differences in terms of altitude were observed, mainly in the 90th and 97th percentiles for both regions and the 3rd and 10th percentiles in the HL compared with the international standard. Conclusions. BW distribution varied in association with altitude; therefore, to assess intrauterine growth, it is critical to include GA and the environment in which the pregnancy takes place.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Birth Weight ; Argentina/epidemiology ; Gestational Age ; Altitude ; Growth Charts ; Reference Values
    Language Spanish
    Publishing date 2023-10-12
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2023-10051.eng
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  3. Article ; Online: Spatial distribution and secular trend (1991-2014) of small for gestational age infants born in Jujuy.

    Revollo, Gabriela B / Dipierri, José E / Díaz, María Del Pilar / Alfaro Gómez, Emma L

    Archivos argentinos de pediatria

    2022  Volume 121, Issue 3, Page(s) e202202661

    Abstract: Introduction. A fetus that does not reach the expected growth potential in utero is considered small for gestational age (SGA). Such restriction depends on genetic and/or environmental factors, being altitude a very relevant factor. This study analyzes ... ...

    Title translation Distribución espacial y tendencia secular (1991-2014) de nacidos pequeños para la edad gestacional en Jujuy.
    Abstract Introduction. A fetus that does not reach the expected growth potential in utero is considered small for gestational age (SGA). Such restriction depends on genetic and/or environmental factors, being altitude a very relevant factor. This study analyzes the spatial distribution of the prevalence of SGA and its secular trend in Jujuy (1991-2014). Materials and methods. The records of 308 469 live births in Jujuy (Health Statistics and Information Department) were analyzed. The prevalence of SGA (weight/gestational age < P10 and < P3) was estimated for sex according to the INTERGROWTH-21st standard in the ecoregions of Jujuy (Valle and Ramal -less than 2000 MASL-, Puna, and Quebrada) across 3 periods (1991-2000, 2001-2009, 2010-2014) and proportions were compared. The secular trend was assessed using the Joinpoint regression analysis. Results. The overall prevalence of SGA was 2.3% (< P3) and 7% (< P10). Significantly higher values were observed in Puna and Quebrada in both SGA categories and across all periods. Only in Valle, significant differences were observed between sexes across all periods. The prevalence of SGA showed a significant downward secular trend at a provincial and regional level, and this was greater in Quebrada (5.2% < P3 and 3.5% < P10). Conclusions. A consistent and significant decrease in the prevalence of SGA has been observed since the 1990s in Jujuy, where altitude is itself a determining factor of size at birth, since the Puna and Quebrada regions showed the highest prevalence of SGA during the entire period.
    MeSH term(s) Infant, Newborn ; Pregnancy ; Female ; Humans ; Infant ; Gestational Age ; Infant, Small for Gestational Age ; Parturition ; Altitude ; Prevalence
    Language Spanish
    Publishing date 2022-12-01
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2022-02661.eng
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  4. Article ; Online: Somatotype altitudinal variation and its relationship with the nutritional status of children in the Jujuy province, Argentina.

    Andrade, Lautaro D / Vilca, Noelia G / Figueroa, Marcelo I / Martínez, Jorge I / Alfaro Gómez, Emma L / Dipierri, José E

    American journal of human biology : the official journal of the Human Biology Council

    2023  Volume 35, Issue 9, Page(s) e23910

    Abstract: Objectives: To study the somatotype variations adjusted by altitude, age, sex, and BMI categories, and to assess the health status of the children population.: Methods: A sample of 460 children aged 8-13 years was assessed in a cross-sectional study ... ...

    Abstract Objectives: To study the somatotype variations adjusted by altitude, age, sex, and BMI categories, and to assess the health status of the children population.
    Methods: A sample of 460 children aged 8-13 years was assessed in a cross-sectional study conducted on anthropometric measurements between 2011 and 2015. Data were categorized into two age groups: Group 8-10, Group 11-13 and two altitudes: Highland (>2000 masl), lowland (<2000 masl). The somatotypic profile was determined by the Heath and Carter's study method and the Body Mass Index was used to assess children nutritional status. Generalized linear latent variable models (GLLVM) were performed to test the association between somatotype and geographic altitude. Individual age-sex specific somatotypes were plotted in a two-dimension somatochart, and group dispersion was displayed by the somatotype attitudinal mean.
    Results: The sample has an overall endomorph-mesomorph body type, exhibiting different patterns when altitude and sex were considered. The GLLVM showed that the whole somatotype was different by altitude. Highland children occupied central to endomorphic-mesomorphic places in the somatochart with lower variation. In both altitudes, girls exhibited higher endomorphy than boys. Several discrepancies between the BMI categorization and the somatotype were observed.
    Conclusions: Jujenean children show differential body patterns across geographic altitude which exhibit age and sex variations. Children have a differential tendency to a fat mass gain. The BMI showed some inconsistencies with somatotype, leading to a misclassification of the child nutritional status, this highlights the importance of not to treat the BMI in isolation but with other determinants of the health status.
    MeSH term(s) Male ; Female ; Humans ; Child ; Somatotypes ; Nutritional Status ; Cross-Sectional Studies ; Argentina ; Body Mass Index ; Anthropometry
    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025339-7
    ISSN 1520-6300 ; 1042-0533
    ISSN (online) 1520-6300
    ISSN 1042-0533
    DOI 10.1002/ajhb.23910
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  5. Article ; Online: Surnames and population structure in the Doctrine of Belén, Altos de Arica, Viceroyalty of Peru (1750-1813).

    Alfaro, Emma / Inostroza, Xochitl / Dipierri, José E / Peña Aguilera, Daniela / Hidalgo, Jorge / Albeck, María Esther

    Journal of biosocial science

    2021  Volume 54, Issue 4, Page(s) 545–557

    Abstract: The analysis of multiple population structures (biodemographic, genetic and socio-cultural) and their inter-relations contribute to a deeper understanding of population structure and population dynamics. Genetically, the population structure corresponds ... ...

    Abstract The analysis of multiple population structures (biodemographic, genetic and socio-cultural) and their inter-relations contribute to a deeper understanding of population structure and population dynamics. Genetically, the population structure corresponds to the deviation of random mating conditioned by a limited number of ancestors, by restricted migration in the social or geographic space, or by preference for certain consanguineous unions. Through the isonymic method, surname frequency and distribution across the population can supply quantitative information on the structure of a human population, as they constitute universal socio-cultural variables. Using documentary sources to undertake the Doctrine of Belén's (Altos de Arica, Chile) historical demography reconstruction between 1763 and 1820, this study identified an indigenous population with stable patronymics. The availability of complete marriage, baptism and death records, low rates of migration and the significant percentage of individuals registered and constantly present in this population favoured the application of the isonymic method. The aim of this work was to use given names and surnames recorded in these documentary sources to reconstruct the population structure and migration pattern of the Doctrine of Belén between 1750 and 1813 through the isonymic method. The results of the study were consistent with the ethno-historical data of this ethnic space, where social cohesion was, in multiple ways, related to the regulation of daily life in colonial Andean societies.
    MeSH term(s) Consanguinity ; Genetics, Population ; Humans ; Marriage ; Names ; Peru ; Population Dynamics
    Language English
    Publishing date 2021-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 390961-x
    ISSN 1469-7599 ; 0021-9320
    ISSN (online) 1469-7599
    ISSN 0021-9320
    DOI 10.1017/S0021932021000389
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  6. Article ; Online: Neonatal anthropometry of malformed newborns: A large South American population-based study.

    Heisecke, Silvina / Alfaro, Emma L / Martínez, Jorge / Figueroa, Marcelo / Bronberg, Rubén / Ratowiecki, Julia / López Camelo, Jorge S / Dipierri, José E

    Paediatric and perinatal epidemiology

    2022  Volume 36, Issue 2, Page(s) 211–219

    Abstract: Background: Population-based anthropometric evaluation of malformed newborns is scarce.: Objectives: To evaluate malformed newborns' foetal growth using the ICD 10 malformations' classification.: Methods: A study including 33,769 newborns (14,857 ... ...

    Abstract Background: Population-based anthropometric evaluation of malformed newborns is scarce.
    Objectives: To evaluate malformed newborns' foetal growth using the ICD 10 malformations' classification.
    Methods: A study including 33,769 newborns (14,857 malformed and 18,912 nonmalformed), selected from 678,840 births from nine South American countries, period 2010-2018, was conducted. Prevalence of severe small and small for gestational age was calculated for malformed and nonmalformed newborns classified by preterm birth categories. Prevalence and relative risk (RR) with its 95% confidence interval (CI) were calculated. The associations between anthropometric phenotypes and congenital malformations were evaluated with generalized linear models.
    Results: Prevalence of preterm and term severe small and small for gestational age newborns was higher in malformed than that in nonmalformed neonates. For grouped ICD 10 malformations categories, the RR for severe small for gestational age was 2.88 (95% CI 2.51, 3.30) and 2.10 (95% CI 1.92, 2.30) for small for gestational age. For at-term and preterm malformed newborns, the RR for severe small for gestational age was 2.21 (95% CI 1.87, 2.61) and 3.21 (95% CI 2.52, 4.10), respectively; for small for gestational age, the RR was 2.31 (95% CI 2.11, 2.53) for at-term newborns and 2.58 (95% CI 2.16, 3.08) for preterm ones.
    Conclusions: Prevalence and relative risk of severe small and small for gestational age vary according to the group of malformations and gestational age; they increase in congenital malformations of the nervous, respiratory and digestive systems, and in chromosomal abnormalities and are lower for malformations of eye, ear, face and neck and cleft lip and palate. Foetal growth considered together with malformed newborns' gestational age would allow for inferring different risks of morbidity and mortality.
    MeSH term(s) Anthropometry ; Cleft Lip ; Cleft Palate ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Small for Gestational Age ; Premature Birth
    Language English
    Publishing date 2022-02-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639089-4
    ISSN 1365-3016 ; 0269-5022 ; 1353-663X
    ISSN (online) 1365-3016
    ISSN 0269-5022 ; 1353-663X
    DOI 10.1111/ppe.12843
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  7. Article ; Online: Epidemiology of sudden unexpected death in infancy in Argentina: secular trend and spatial variation.

    Chapur, Valeria F / Alfaro, Emma L / Bronberg, Rubén / Dipierri, José E

    Archivos argentinos de pediatria

    2019  Volume 117, Issue 3, Page(s) 164–170

    Abstract: Introduction: Infant mortality comprises deaths among infants younger than one year old. The proportion of sudden unexpected death in infancy (SUDI) varies by country and based on the cause of death.: Objective: To describe the spatial and temporal ... ...

    Title translation Epidemiología de las muertes súbitas infantiles inesperadas en Argentina: tendencia secular y variación espacial.
    Abstract Introduction: Infant mortality comprises deaths among infants younger than one year old. The proportion of sudden unexpected death in infancy (SUDI) varies by country and based on the cause of death.
    Objective: To describe the spatial and temporal variation of SUDI in Argentina between 1991 and 2014 according to the International Classification of Diseases, tenth revision.
    Materials and methods: Based on infant death data (provided by the Health Statistics and Information Department), we estimated the percentage of SUDI over the total number of infant deaths and the frequency of causes of death at a provincial, regional, and national level. The risk for death and the secular trend were estimated using a Poisson regression. The SaTScan software, v9.1.1, was used to detect clusters of districts where the percentage of SUDI was significantly different from the national percentage.
    Results: In Argentina, between 1991 and 2014, 267 552 infants younger than 1 year died; 7 % corresponded to SUDI; the secular trend of causes was negative and statistically significant; the risk for SUDI was 0.86, and a great spatial heterogeneity was observed. At a national level, the most common cause was sudden infant death syndrome, with inter-regional differences. In nine district clusters, the risk for SUDI ranged between 4.36 and 1.24, which is significantly different from the rest of the country.
    Conclusions: The proportion of SUDI and its causes show inter-regional heterogeneity; codes related to inaccurate diagnoses predominated in more unfavorable regions, while sudden infant death syndrome was prevalent in the more developed regions.
    MeSH term(s) Argentina/epidemiology ; Humans ; Infant ; Infant Mortality/trends ; Retrospective Studies ; Spatial Analysis ; Sudden Infant Death/diagnosis ; Sudden Infant Death/epidemiology
    Language Spanish
    Publishing date 2019-05-06
    Publishing country Argentina
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424449-7
    ISSN 1668-3501 ; 0325-0075 ; 0004-0487
    ISSN (online) 1668-3501
    ISSN 0325-0075 ; 0004-0487
    DOI 10.5546/aap.2019.eng.164
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  8. Article ; Online: Newborn anthropometry, maternal capital, and altitude in the highland population from the province of Jujuy, Argentina.

    Martínez, Jorge I / Figueroa, Marcelo I / Alfaro Gómez, Emma L / Dipierri, José E

    American journal of physical anthropology

    2020  Volume 175, Issue 1, Page(s) 25–35

    Abstract: Objective: To analyze variability in newborn (NB) anthropometry among Jujenean NBs as a function of geographic altitude (500 m to ≈4000 masl), maternal anthropometry and other maternal characteristics within the maternal capital framework.: Materials ... ...

    Abstract Objective: To analyze variability in newborn (NB) anthropometry among Jujenean NBs as a function of geographic altitude (500 m to ≈4000 masl), maternal anthropometry and other maternal characteristics within the maternal capital framework.
    Materials and methods: Data obtained from 41,371 mother/child pairs recorded in the Jujuy Perinatal Information System (SIP) between 2009 and 2014, including: NB and maternal weight, length/height and BMI; gestational age (corrected); maternal age, educational level, nutritional status, and marital status; birth interval; and planned pregnancy. Based on the declared place of residence, the prevalence of unsatisfied basic needs (% UBN) was determined and the data was split into two altitudinal groups: highlands (HL, >2500 masl) and lowlands (LL, <2500 masl). ANOVA, Chi-squared and Pearson tests were applied as needed. Statistical associations between the response variables-NB weight, length and BMI-and maternal and environmental variables were tested using a Generalized Additive Mixed Model (GAMM).
    Results: All NB and maternal anthropometric variables were lower in HL compared to LL; they also presented negative correlations with altitude, except NB length. Apart from gestational age and birth interval, HL and LL presented statistically significant differences in all study variables. GAMM results showed that maternal anthropometry was the main influence on NB weight and length.
    Discussion: Of all the maternal capital features examined, only maternal anthropometric variables were found to protect offspring against the negative impact of HL environments.
    MeSH term(s) Adult ; Humans ; Infant, Newborn/physiology ; Young Adult ; Altitude ; Anthropology, Physical ; Anthropometry ; Argentina ; Body Weight/physiology ; Educational Status ; Gestational Age ; Indians, South American/statistics & numerical data ; Maternal Age ; Maternal Health/statistics & numerical data ; Mothers/statistics & numerical data ; Nutritional Status/physiology ; Retrospective Studies ; Female ; Pregnancy
    Language English
    Publishing date 2020-12-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219376-0
    ISSN 1096-8644 ; 0002-9483
    ISSN (online) 1096-8644
    ISSN 0002-9483
    DOI 10.1002/ajpa.24215
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  9. Article ; Online: Proportionality indices, geographic altitude, and gestational age in newborns from Jujuy, Argentina.

    Martínez, Jorge I / Revollo, Gabriela B / Alfaro, Emma L / Grandi, Carlos / Dipierri, José E

    American journal of human biology : the official journal of the Human Biology Council

    2020  Volume 33, Issue 1, Page(s) e23454

    Abstract: Background: There are several different proportionality indices (PRIs) to evaluate size at birth by gestational age (GA). Yet, the explanatory power of alternative PRIs has not been evaluated in highland (HL) populations.: Aim: Evaluate the relative ... ...

    Abstract Background: There are several different proportionality indices (PRIs) to evaluate size at birth by gestational age (GA). Yet, the explanatory power of alternative PRIs has not been evaluated in highland (HL) populations.
    Aim: Evaluate the relative utility of three PRIs, weight to length ratio (W/L), body mass index (BMI), and ponderal index (PI), for assessing nutritional status in newborns (NBs) from highland (HL ≥ 2000 m) and lowland (LL < 2000 m) regions of the Jujuy Province of Argentina.
    Subjects and methods: Births were registered by the Ministry of Health (Jujuy, 2009-2014). Data were grouped according to HL and LL altitude groups based on of maternal residence. The main outcome measures were the PRIs W/L ratio, BMI, and PI. Percentiles were generated by the LMS method and compared with references. ANOVAs and Pearson correlations were used to examine the relationship between outcome measures with weight and length by altitude, sex, and GA.
    Results: In both altitude zones, W/L and BMI increased with GA, while PI stabilized between 37th and 42th weeks. The LL sample had significantly higher values for all the PRIs from the 37th week of GA. In the HL sample, the 50th percentiles for all three PRIs were lower than the reference. Regardless of GA and altitude level, BMI showed the lowest correlation with length and the higher with the weight.
    Conclusion: The HL sample of term NBs had lower values for all PRIs compared to their LL counterparts. In both altitude zones, the BMI is the preferred PRI to evaluate the nutritional status.
    MeSH term(s) Altitude ; Argentina ; Body Mass Index ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Male ; Nutritional Status
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025339-7
    ISSN 1520-6300 ; 1042-0533
    ISSN (online) 1520-6300
    ISSN 1042-0533
    DOI 10.1002/ajhb.23454
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  10. Article ; Online: Paternal heritage in Jujuy province (Northwest Argentina): Evidence for sex-biased gene flow and genetic drift effects.

    Alfonso-Sánchez, Miguel A / Gómez-Pérez, Luis / Dipierri, José E / Peña, José A

    American journal of human biology : the official journal of the Human Biology Council

    2019  Volume 31, Issue 4, Page(s) e23262

    Abstract: Objectives: This study aimed to explore the diversity of paternal lineages in Jujuy province (Argentina) by analyzing Y chromosome markers. Furthermore, we examined among-population genetic variability based both on paternally (NRY haplotypes) and ... ...

    Abstract Objectives: This study aimed to explore the diversity of paternal lineages in Jujuy province (Argentina) by analyzing Y chromosome markers. Furthermore, we examined among-population genetic variability based both on paternally (NRY haplotypes) and maternally (mtDNA haplogroups) inherited markers. We sought to evaluate the impact of sex-biased gene flow on genetic background in Jujuy, and contribute data on the microevolutionary forces acting in this zone.
    Methods: DNA from 149 males from five Jujuy regions were analyzed for 12 non-recombining Y (NRY) markers. Genetic heterogeneity among Jujuy regions was evaluated through population differentiation tests. To identify potential genetic boundaries in Jujuy, analysis of molecular variance (AMOVA) and the Monmonier's algorithm implemented in the Barrier v2.2 software were employed.
    Results: A clear divergence between Jujuy highlands and lowlands for NRY haplotypes was found. A marked discrepancy between genetic structuring for paternal lineages and the lack of geographical pattern for mitogenomes was confirmed by all statistical analyses.
    Conclusions: Genetic structuring of paternal lineages is most likely caused by admixture processes that have occurred since colonial times in the Jujuy lowlands. Immigrants were predominantly male that settled in the lower altitude zones, due to the steep orography of the region. Input of allochthonous male lineages because of gene flow toward the lowlands would have increased diversity of NRY markers, thus compensating for drift effects. Likewise, limited input of allochthonous mitogenomes would have promoted genetic drift, a key factor in the shaping of diversity of maternal lineages across Jujuy subpopulations, irrespective of altitude.
    MeSH term(s) Argentina ; Gene Flow ; Genetic Drift ; Humans ; Indians, South American/genetics ; Male ; Paternal Inheritance ; Sex Factors
    Language English
    Publishing date 2019-05-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025339-7
    ISSN 1520-6300 ; 1042-0533
    ISSN (online) 1520-6300
    ISSN 1042-0533
    DOI 10.1002/ajhb.23262
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