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  1. Article ; Online: Predictors and Outcomes of Dengue-Associated Acute Kidney Injury.

    Diptyanusa, Ajib / Phumratanaprapin, Weerapong

    The American journal of tropical medicine and hygiene

    2021  Volume 105, Issue 1, Page(s) 24–30

    Abstract: Dengue viral infections present with a wide clinical spectrum ranging from asymptomatic to severe manifestations with organ involvement. The term "expanded dengue syndrome" has been commonly used to illustrate the unusual or atypical manifestations; ... ...

    Abstract Dengue viral infections present with a wide clinical spectrum ranging from asymptomatic to severe manifestations with organ involvement. The term "expanded dengue syndrome" has been commonly used to illustrate the unusual or atypical manifestations; acute kidney injury (AKI) is one of the atypical manifestations of this syndrome. The use of heterogeneous criteria to determine the presence of AKI in dengue patients due to the vast diversity in populations led to difficulties in assessing the true incidence of dengue-associated AKI. This review presents a variable, but often high, frequency of dengue-associated AKI among vastly diverse populations with various disease severities. Dengue-associated AKI is not an uncommon complication, and its importance has often been neglected during the management of dengue patients. The risk factors and certain clinical and laboratory findings commonly reported among dengue patients with AKI should be considered to support a timely diagnosis and case management. This review highlights the need for clinicians to be aware of dengue-associated AKI to reduce the morbidity and mortality associated with this common and important tropical disease.
    MeSH term(s) Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Acute Kidney Injury/physiopathology ; Dengue/complications ; Dengue/epidemiology ; Dengue/physiopathology ; Epidemiological Monitoring ; Forecasting ; Humans ; Incidence ; Risk Factors
    Language English
    Publishing date 2021-05-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.21-0007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Treatment of human intestinal cryptosporidiosis: A review of published clinical trials.

    Diptyanusa, Ajib / Sari, Ika Puspa

    International journal for parasitology. Drugs and drug resistance

    2021  Volume 17, Page(s) 128–138

    Abstract: The global burden of diarrhea caused by Cryptosporidium parasite is underestimated. In immunocompromised hosts, chronic and severe presentation of intestinal cryptosporidiosis can result in long-term morbidity and high illness costs. The evidence of ... ...

    Abstract The global burden of diarrhea caused by Cryptosporidium parasite is underestimated. In immunocompromised hosts, chronic and severe presentation of intestinal cryptosporidiosis can result in long-term morbidity and high illness costs. The evidence of effective treatments for cryptosporidiosis has been lacking. We reviewed the published clinical trials to bring forward the feasible therapeutic options of human cryptosporidiosis in various populations and settings according to clinical improvement and parasite clearance rates. A total of 42 studies consisting of the use of nitazoxanide, paromomycin, macrolides, somatostatin analogues, letrazuril, albendazole, rifaximin, miltefosine, clofazimine, and colostrum were included in the review. The trials were mostly conducted in small number of individuals infected with human immunodeficiency virus (HIV), and there is inadequate data of controlled trials to suggest the use of these treatment modalities. Nitazoxanide was reported to be highly efficacious only in immunocompetent hosts and was found to be superior to paromomycin in the same group of patients. Macrolides showed no effective results in both clinical and parasitological improvement. Human bovine colostrum should possibly be administered as one of complementary therapeutic modalities along with other antimicrobials to reach optimal parasite eradication. Other trials of therapeutic modalities were terminated due to futility. Currently, available data is intended to aid the development of strategies for improving access to treatments in different clinical settings, as well as to help guide further studies on treatments of human intestinal cryptosporidiosis.
    MeSH term(s) Animals ; Antiprotozoal Agents/therapeutic use ; Cattle ; Clinical Trials as Topic ; Cryptosporidiosis/drug therapy ; Cryptosporidiosis/epidemiology ; Cryptosporidium ; Diarrhea/drug therapy ; Humans ; Paromomycin/therapeutic use
    Chemical Substances Antiprotozoal Agents ; Paromomycin (61JJC8N5ZK)
    Language English
    Publishing date 2021-09-21
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2751132-7
    ISSN 2211-3207 ; 2211-3207
    ISSN (online) 2211-3207
    ISSN 2211-3207
    DOI 10.1016/j.ijpddr.2021.09.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Asymptomatic Cryptosporidiosis in Children Living with HIV.

    Diptyanusa, Ajib / Sari, Ika Puspa / Kurniawan, Agnes

    Tropical medicine and infectious disease

    2022  Volume 7, Issue 11

    Abstract: Children living with human immunodeficiency virus (HIV) have an increased risk of ... ...

    Abstract Children living with human immunodeficiency virus (HIV) have an increased risk of opportunistic
    Language English
    Publishing date 2022-11-04
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed7110352
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  4. Article ; Online: Addressing budget reduction and reallocation on health-related resources during COVID-19 pandemic in malaria-endemic countries.

    Diptyanusa, Ajib / Zablon, Karen Nelwin

    Malaria journal

    2020  Volume 19, Issue 1, Page(s) 411

    Abstract: The global COVID-19 pandemic has been affecting the maintenance of various disease control programmes, including malaria. In some malaria-endemic countries, funding and personnel reallocations were executed from malaria control programmes to support ... ...

    Abstract The global COVID-19 pandemic has been affecting the maintenance of various disease control programmes, including malaria. In some malaria-endemic countries, funding and personnel reallocations were executed from malaria control programmes to support COVID-19 response efforts, resulting mainly in interruptions of disease control activities and reduced capabilities of health system. While it is principal to drive national budget rearrangements during the pandemic, the long-standing malaria control programmes should not be left behind in order to sustain the achievements from the previous years. With different levels of intensity, many countries have been struggling to improve the health system resilience and to mitigate the unavoidable stagnation of malaria control programmes. Current opinion emphasized the impacts of budget reprioritization on malaria-related resources during COVID-19 pandemic in malaria endemic countries in Africa and Southeast Asia, and feasible attempts that can be taken to lessen these impacts.
    MeSH term(s) Africa ; Asia, Southeastern ; Budgets/statistics & numerical data ; Budgets/trends ; COVID-19 ; Coronavirus Infections/economics ; Coronavirus Infections/prevention & control ; Endemic Diseases/economics ; Endemic Diseases/prevention & control ; Health Resources/economics ; Health Resources/trends ; Humans ; Malaria/economics ; Malaria/prevention & control ; Mosquito Control/economics ; Mosquito Control/trends ; Pandemics/economics ; Pandemics/prevention & control ; Pneumonia, Viral/economics ; Pneumonia, Viral/prevention & control
    Keywords covid19
    Language English
    Publishing date 2020-11-16
    Publishing country England
    Document type Letter
    ISSN 1475-2875
    ISSN (online) 1475-2875
    DOI 10.1186/s12936-020-03488-y
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  5. Article ; Online: Estimation of Japanese encephalitis virus infection prevalence in mosquitoes and bats through nationwide sentinel surveillance in Indonesia.

    Diptyanusa, Ajib / Herini, Elisabeth Siti / Indarjulianto, Soedarmanto / Satoto, Tri Baskoro Tunggul

    PloS one

    2022  Volume 17, Issue 10, Page(s) e0275647

    Abstract: Indonesia belongs to endemic areas of Japanese encephalitis (JE), yet data regarding the true risk of disease transmission are lacking. While many seroprevalence studies reported its classic enzootic transmission, data related to the role of bats in the ... ...

    Abstract Indonesia belongs to endemic areas of Japanese encephalitis (JE), yet data regarding the true risk of disease transmission are lacking. While many seroprevalence studies reported its classic enzootic transmission, data related to the role of bats in the transmission of JE virus are limited. This current study aimed to identify the potential role of bats in the local transmission of the JE virus to aid the ongoing active case surveillance in Indonesia, in order to estimate the transmission risk. Mosquitoes and bats were collected from 11 provinces in Indonesia. The detection of the JE virus used polymerase chain reaction (PCR). Maps were generated to analyze the JE virus distribution pattern. Logistic regression analysis was done to identify risk factors of JE virus transmission. JE virus was detected in 1.4% (7/483) of mosquito pools and in 2.0% (68/3,322) of bat samples. Mosquito species positive for JE virus were Culex tritaeniorhynchus and Cx. vishnui, whereas JE-positive bats belonged to the genera Cynopterus, Eonycteris, Hipposideros, Kerivoula, Macroglossus, Pipistrellus, Rousettus, Scotophilus and Thoopterus. JE-positive mosquitoes were collected at the same sites as the JE-positive bats. Collection site nearby human dwellings (AOR: 2.02; P = 0.009) and relative humidity of >80% (AOR: 2.40; P = 0.001) were identified as independent risk factors for JE virus transmission. The findings of the current study highlighted the likely ongoing risk of JE virus transmission in many provinces in Indonesia, and its potential implications on human health.
    MeSH term(s) Animals ; Chiroptera ; Culex ; Culicidae ; Encephalitis Virus, Japanese ; Encephalitis, Japanese ; Humans ; Indonesia/epidemiology ; Prevalence ; Sentinel Surveillance ; Seroepidemiologic Studies
    Language English
    Publishing date 2022-10-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0275647
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  6. Article: Addressing budget reduction and reallocation on health-related resources during COVID-19 pandemic in malaria-endemic countries

    Diptyanusa, Ajib / Zablon, Karen Nelwin

    Malar J

    Abstract: The global COVID-19 pandemic has been affecting the maintenance of various disease control programmes, including malaria. In some malaria-endemic countries, funding and personnel reallocations were executed from malaria control programmes to support ... ...

    Abstract The global COVID-19 pandemic has been affecting the maintenance of various disease control programmes, including malaria. In some malaria-endemic countries, funding and personnel reallocations were executed from malaria control programmes to support COVID-19 response efforts, resulting mainly in interruptions of disease control activities and reduced capabilities of health system. While it is principal to drive national budget rearrangements during the pandemic, the long-standing malaria control programmes should not be left behind in order to sustain the achievements from the previous years. With different levels of intensity, many countries have been struggling to improve the health system resilience and to mitigate the unavoidable stagnation of malaria control programmes. Current opinion emphasized the impacts of budget reprioritization on malaria-related resources during COVID-19 pandemic in malaria endemic countries in Africa and Southeast Asia, and feasible attempts that can be taken to lessen these impacts.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #927504
    Database COVID19

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  7. Article ; Online: Implementation of geographical information systems for the study of diseases caused by vector-borne arboviruses in Southeast Asia: A review based on the publication record.

    Diptyanusa, Ajib / Lazuardi, Lutfan / Jatmiko, Retnadi Heru

    Geospatial health

    2020  Volume 15, Issue 1

    Abstract: The spread of mosquito-borne diseases in Southeast Asia has dramatically increased in the latest decades. These infections include dengue, chikungunya and Japanese Encephalitis (JE), high-burden viruses sharing overlapping disease manifestation and ... ...

    Abstract The spread of mosquito-borne diseases in Southeast Asia has dramatically increased in the latest decades. These infections include dengue, chikungunya and Japanese Encephalitis (JE), high-burden viruses sharing overlapping disease manifestation and vector distribution. The use of Geographical Information Systems (GIS) to monitor the dynamics of disease and vector distribution can assist in disease epidemic prediction and public health interventions, particularly in Southeast Asia where sustained high temperatures drive the epidemic spread of these mosquito-borne viruses. Due to lack of accurate data, the spatial and temporal dynamics of these mosquito-borne viral disease transmission countries are poorly understood, which has limited disease control effort. By following studies carried out on these three viruses across the region in a specific time period revealing general patterns of research activities and characteristics, this review finds the need to improve decision-support by disease mapping and management. The results presented, based on a publication search with respect to diseases due to arboviruses, specifically dengue, chikungunya and Japanese encephalitis, should improve opportunities for future studies on the implementation of GIS in the control of mosquito-borne viral diseases in Southeast Asia.
    MeSH term(s) Animals ; Arbovirus Infections/epidemiology ; Arbovirus Infections/transmission ; Arboviruses ; Asia, Southeastern/epidemiology ; Dengue/transmission ; Disease Vectors ; Geographic Information Systems ; Humans ; Mosquito Vectors
    Language English
    Publishing date 2020-06-17
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2276179-2
    ISSN 1970-7096 ; 1827-1987
    ISSN (online) 1970-7096
    ISSN 1827-1987
    DOI 10.4081/gh.2020.862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Health Belief Model of Persistent Dengue Transmission in Klaten, Indonesia.

    Diptyanusa, Ajib / Kusumasari, Rizqiani Amalia / Satoto, Tri Baskoro Tunggul

    American journal of health behavior

    2020  Volume 44, Issue 2, Page(s) 188–199

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Adult ; Dengue/prevention & control ; Dengue/transmission ; Female ; Focus Groups ; Health Belief Model ; Humans ; Indonesia ; Male ; Middle Aged ; Qualitative Research
    Language English
    Publishing date 2020-02-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1312417-1
    ISSN 1945-7359 ; 1087-3244 ; 0147-0353
    ISSN (online) 1945-7359
    ISSN 1087-3244 ; 0147-0353
    DOI 10.5993/AJHB.44.2.7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  9. Article: The detection of Japanese encephalitis virus in Megachiropteran bats in West Kalimantan, Indonesia: A potential enzootic transmission pattern in the absence of pig holdings.

    Diptyanusa, Ajib / Herini, Elisabeth Siti / Indarjulianto, Soedarmanto / Satoto, Tri Baskoro Tunggul

    International journal for parasitology. Parasites and wildlife

    2021  Volume 14, Page(s) 280–286

    Abstract: The West Kalimantan province in Borneo island, Indonesia belongs to endemic area of Japanese encephalitis (JE) that accounts for approximately 30% of total cases yearly. As the presence of pig holdings is uncommon in West Kalimantan, another reservoir ... ...

    Abstract The West Kalimantan province in Borneo island, Indonesia belongs to endemic area of Japanese encephalitis (JE) that accounts for approximately 30% of total cases yearly. As the presence of pig holdings is uncommon in West Kalimantan, another reservoir host might have played a role in the local transmission of JE virus in this area. Current study aimed to identify the potential role of bats in the local transmission of JE by performing molecular detection of JE virus in bats and mosquitoes using RT-PCR. Sample collection was performed in 3 districts in West Kalimantan, covering 3 different ecosystems: forest, coastal, and residential areas. Bat collection was performed using mist net and harp net, while mosquito collection was carried out using animal-baited trap and human landing collection. A total of 373 blood samples from bats were tested for JE virus, among which 21 samples (5.6%) showed positive results, mainly from
    Language English
    Publishing date 2021-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2715239-X
    ISSN 2213-2244
    ISSN 2213-2244
    DOI 10.1016/j.ijppaw.2021.03.009
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  10. Article: Stunting as a Risk Factor of Soil-Transmitted Helminthiasis in Children: A Literature Review.

    Fauziah, Nisa / Ar-Rizqi, Muhammad Abdurrahman / Hana, Sofia / Patahuddin, Nurul Mufliha / Diptyanusa, Ajib

    Interdisciplinary perspectives on infectious diseases

    2022  Volume 2022, Page(s) 8929025

    Abstract: As a high-burden neglected tropical disease, soil-transmitted helminth (STH) infections remain a major problem in the world, especially among children under five years of age. Since young children are at high risk of being infected, STH infection can ... ...

    Abstract As a high-burden neglected tropical disease, soil-transmitted helminth (STH) infections remain a major problem in the world, especially among children under five years of age. Since young children are at high risk of being infected, STH infection can have a long-term negative impact on their life, including impaired growth and development. Stunting, a form of malnutrition in young children, has been long assumed as one of the risk factors in acquiring the STH infections. However, the studies on STH infection in children under five with stunting have been lacking, resulting in poor identification of the risk. Accordingly, we collected and reviewed existing related research articles to provide an overview of STH infection in a susceptible population of stunted children under five years of age in terms of prevalence and risk factors. There were 17 studies included in this review related to infection with
    Language English
    Publishing date 2022-08-03
    Publishing country Egypt
    Document type Journal Article ; Review
    ZDB-ID 2478373-0
    ISSN 1687-7098 ; 1687-708X
    ISSN (online) 1687-7098
    ISSN 1687-708X
    DOI 10.1155/2022/8929025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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