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  1. Article ; Online: Mouse-Adapted SARS-CoV-2 MA10 Strain Displays Differential Pulmonary Tropism and Accelerated Viral Replication, Neurodissemination, and Pulmonary Host Responses in K18-hACE2 Mice.

    Thieulent, Côme J / Dittmar, Wellesley / Balasuriya, Udeni B R / Crossland, Nicholas A / Wen, Xue / Richt, Juergen A / Carossino, Mariano

    mSphere

    2023  Volume 8, Issue 1, Page(s) e0055822

    Abstract: Several models were developed to study the pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as ... ...

    Abstract Several models were developed to study the pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as well as the
    MeSH term(s) Mice ; Humans ; Animals ; SARS-CoV-2 ; COVID-19/pathology ; Angiotensin-Converting Enzyme 2/genetics ; Pandemics ; Lung/pathology ; Virus Replication ; Mice, Transgenic ; Tropism
    Chemical Substances Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; K-18 conjugate
    Language English
    Publishing date 2023-02-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00558-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ACE2 and TMPRSS2 distribution in the respiratory tract of different animal species and its correlation with SARS-CoV-2 tissue tropism.

    Carossino, Mariano / Izadmehr, Sudeh / Trujillo, Jessie D / Gaudreault, Natasha N / Dittmar, Wellesley / Morozov, Igor / Balasuriya, Udeni B R / Cordon-Cardo, Carlos / García-Sastre, Adolfo / Richt, Juergen A

    Microbiology spectrum

    2024  Volume 12, Issue 2, Page(s) e0327023

    Abstract: A wide range of animal species show variable susceptibility to SARS-CoV-2; however, host factors associated with varied susceptibility remain to be defined. Here, we examined whether susceptibility to SARS-CoV-2 and virus tropism in different animal ... ...

    Abstract A wide range of animal species show variable susceptibility to SARS-CoV-2; however, host factors associated with varied susceptibility remain to be defined. Here, we examined whether susceptibility to SARS-CoV-2 and virus tropism in different animal species are dependent on the expression and distribution of the virus receptor angiotensin-converting enzyme 2 (
    MeSH term(s) Humans ; Animals ; SARS-CoV-2 ; COVID-19 ; Angiotensin-Converting Enzyme 2 ; Deer ; Respiratory System ; RNA, Messenger ; Tropism ; Serine Endopeptidases
    Chemical Substances Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; RNA, Messenger ; TMPRSS2 protein, human (EC 3.4.21.-) ; Serine Endopeptidases (EC 3.4.21.-)
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03270-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spotted Fever Group

    Suwanbongkot, Chanakan / Langohr, Ingeborg M / Harris, Emma K / Dittmar, Wellesley / Christofferson, Rebecca C / Macaluso, Kevin R

    Infection and immunity

    2019  Volume 87, Issue 4

    Abstract: Tick vectors are capable of transmitting several rickettsial species to vertebrate hosts, resulting in various levels of disease. Studies have demonstrated the transmissibility of both rickettsial pathogens and ... ...

    Abstract Tick vectors are capable of transmitting several rickettsial species to vertebrate hosts, resulting in various levels of disease. Studies have demonstrated the transmissibility of both rickettsial pathogens and novel
    MeSH term(s) Animals ; Arachnid Vectors/microbiology ; Arachnid Vectors/physiology ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Feeding Behavior ; Female ; Humans ; Ixodidae/microbiology ; Ixodidae/physiology ; Male ; Nymph/microbiology ; Rickettsia/genetics ; Rickettsia/isolation & purification ; Rickettsia/physiology ; Saliva/microbiology ; Salivary Glands/microbiology ; Spotted Fever Group Rickettsiosis/microbiology ; Spotted Fever Group Rickettsiosis/transmission
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2019-03-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00804-18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Modeling the pasture-associated severe equine asthma bronchoalveolar lavage fluid proteome identifies molecular events mediating neutrophilic airway inflammation.

    Bright, Lauren A / Dittmar, Wellesley / Nanduri, Bindu / McCarthy, Fiona M / Mujahid, Nisma / Costa, Lais Rr / Burgess, Shane C / Swiderski, Cyprianna E

    Veterinary medicine (Auckland, N.Z.)

    2019  Volume 10, Page(s) 43–63

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2019-05-02
    Publishing country New Zealand
    Document type Journal Article
    ISSN 2230-2034
    ISSN (online) 2230-2034
    DOI 10.2147/VMRR.S194427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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