LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Djomkam Zune, Alexandra Lindsey"
  2. AU="Magar, Naresh Khapangi"
  3. AU="Martínez-Gómez, David"
  4. AU="Prieto-Arevalo, Raquel"
  5. AU="McLaughlin, Noel P"
  6. AU=Wong Samson S Y AU=Wong Samson S Y
  7. AU="Campolo, Nicolás"
  8. AU="Abraham, Deborah"
  9. AU="Alqurashi, Thamer M A"
  10. AU="Stretton, Alexandra"
  11. AU="Teixeira, Jorge Juarez Vieira"
  12. AU="Keime, Céline"
  13. AU="Mateczun, Alfred"
  14. AU="Peterson, Erica"
  15. AU="Navarro-Amuedo, María Dolores"
  16. AU="Michellier, C"
  17. AU="Stephan Immenschuh"
  18. AU="Phillips, Sabrina"
  19. AU="Fadilah Fadilah"
  20. AU="Kira, Kei"
  21. AU="Modesto, Irene"
  22. AU="Bertha Rita Castillo Edua"
  23. AU="Hannah Danbury"
  24. AU="Elramly, Mohamed"
  25. AU="Louella, Michael"
  26. AU=Bolton Judy L
  27. AU="Riederer, Cordula"
  28. AU="Bao, Qi"
  29. AU="Tsang, Stephen H"
  30. AU="Isaranuwatchai, Wanrudee" AU="Isaranuwatchai, Wanrudee"
  31. AU="Goldring, Mary B"
  32. AU="Durrington, Charlotte"
  33. AU="Metka, M."
  34. AU="González Villarroel, Paula"
  35. AU="Gakuya, F."
  36. AU="Belloni-Fortina, Anna"
  37. AU="Teufel, Frank"

Suchergebnis

Treffer 1 - 7 von insgesamt 7

Suchoptionen

  1. Artikel ; Online: Suboptimal antimicrobial stewardship in the COVID-19 era: is humanity staring at a postantibiotic future?

    Owoicho, Oloche / Tapela, Kesego / Djomkam Zune, Alexandra Lindsey / Nghochuzie, Nora Nganyewo / Isawumi, Abiola / Mosi, Lydia

    Future microbiology

    2021  Band 16, Seite(n) 919–925

    Abstract: In the absence of potent antimicrobial agents, it is estimated that bacterial infections could cause millions of deaths. The emergence of COVID-19, its complex pathophysiology and the high propensity of patients to coinfections has resulted in ... ...

    Abstract In the absence of potent antimicrobial agents, it is estimated that bacterial infections could cause millions of deaths. The emergence of COVID-19, its complex pathophysiology and the high propensity of patients to coinfections has resulted in therapeutic regimes that use a cocktail of antibiotics for disease management. Suboptimal antimicrobial stewardship in this era and the slow pace of drug discovery could result in large-scale drug resistance, narrowing future antimicrobial therapeutics. Thus, judicious use of current antimicrobials is imperative to keep up with existing and emerging infectious pathogens. Here, we provide insights into the potential implications of suboptimal antimicrobial stewardship, resulting from the emergence of COVID-19, on the spread of antimicrobial resistance.
    Mesh-Begriff(e) Anti-Infective Agents/therapeutic use ; Antimicrobial Stewardship/methods ; Bacterial Infections/drug therapy ; Bacterial Infections/epidemiology ; COVID-19/epidemiology ; Coinfection/drug therapy ; Coinfection/epidemiology ; Hand Disinfection ; Humans ; Mycoses/drug therapy ; Mycoses/epidemiology
    Chemische Substanzen Anti-Infective Agents
    Sprache Englisch
    Erscheinungsdatum 2021-07-28
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2021-0008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  2. Artikel ; Online: Knowledge, attitude and perception towards COVID-19 among representative educated sub-Saharan Africans: A cross-sectional study during the exponential phase of the pandemic.

    Udoakang, Aniefiok John / Nganyewo, Nora Nghochuzie / Djomkam Zune, Alexandra Lindsey / Olwal, Charles Ochieng' / Etim, Nsikak-Abasi Aniefiok / Oboh, Mary Aigbiremo / Tapela, Kesego / Dzabeng, Francis / Adadey, Samuel Mawuli / Udoh, Agnes / Koné, Mazo / Mutungi, Joe Kimanthi / Quashie, Peter Kojo / Awandare, Gordon Akanzuwine / Paemka, Lily

    PloS one

    2024  Band 19, Heft 2, Seite(n) e0281342

    Abstract: Coronavirus disease 2019 (COVID-19) pandemic, caused by the Severe Acute Coronavirus 2 (SARS-CoV-2), is a global health threat with extensive misinformation and conspiracy theories. Therefore, this study investigated the knowledge, attitude and ... ...

    Abstract Coronavirus disease 2019 (COVID-19) pandemic, caused by the Severe Acute Coronavirus 2 (SARS-CoV-2), is a global health threat with extensive misinformation and conspiracy theories. Therefore, this study investigated the knowledge, attitude and perception of sub-Saharan Africans (SSA) on COVID-19 during the exponential phase of the pandemic. In this cross-sectional survey, self-administered web-based questionnaires were distributed through several online platforms. A total of 1046 respondents from 35 SSA countries completed the survey. The median age was 33 years (18-76 years) and about half (50.5%) of them were males. More than 40% across all socio-demographic categories except the Central African region (21.2%), vocational/secondary education (28.6%), student/unemployed (35.5%), had high COVID-19 knowledge score. Socio-demographic factors and access to information were associated with COVID-19 knowledge. Bivariate analysis revealed that independent variables, including the region of origin, age, gender, education and occupation, were significantly (p < 0.05) associated with COVID-19 knowledge. Multivariate analysis showed that residing in East (odds ratio [OR]: 7.9, 95% confidence interval (CI): 4.7-14, p<0.001), Southern (OR: 3.7, 95% CI: 2.1-6.5, p<0.001) and West (OR: 3.9, 95% CI: 2.9-5.2, p<0.001) Africa was associated with high COVID-19 knowledge level. Apart from East Africa (54.7%), willingness for vaccine acceptance across the other SSA regions was <40%. About 52%, across all socio-demographic categories, were undecided. Knowledge level, region of origin, age, gender, marital status and religion were significantly (p < 0.05) associated with COVID-19 vaccine acceptance. About 67.4% were worried about contracting SARS-CoV-2, while 65.9% indicated they would consult a health professional if exposed. More than one-third of the respondents reported that their governments had taken prompt measures to tackle the pandemic. Despite high COVID-19 knowledge in our study population, most participants were still undecided regarding vaccination, which is critical in eliminating the pandemic. Therefore, extensive, accurate, dynamic and timely education in this aspect is of ultimate priority.
    Mesh-Begriff(e) Male ; Humans ; Adult ; Female ; COVID-19/epidemiology ; Cross-Sectional Studies ; SARS-CoV-2 ; COVID-19 Vaccines ; Health Knowledge, Attitudes, Practice ; Pandemics ; Surveys and Questionnaires ; Perception ; Africa South of the Sahara/epidemiology
    Chemische Substanzen COVID-19 Vaccines
    Sprache Englisch
    Erscheinungsdatum 2024-02-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0281342
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: The COVID-19, tuberculosis and HIV/AIDS: Ménage à Trois.

    Udoakang, Aniefiok John / Djomkam Zune, Alexandra Lindsey / Tapela, Kesego / Nganyewo, Nora Nghochuzie / Olisaka, Frances Ngozi / Anyigba, Claudia Adzo / Tawiah-Eshun, Sylvia / Owusu, Irene Amoakoh / Paemka, Lily / Awandare, Gordon A / Quashie, Peter Kojo

    Frontiers in immunology

    2023  Band 14, Seite(n) 1104828

    Abstract: In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in China and spread globally. The presentation of COVID-19 is more severe in persons ... ...

    Abstract In December 2019, a novel pneumonic condition, Coronavirus disease 2019 (COVID- 19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in China and spread globally. The presentation of COVID-19 is more severe in persons with underlying medical conditions such as Tuberculosis (TB), Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) and other pneumonic conditions. All three diseases are of global concern and can significantly affect the lungs with characteristic cytokine storm, immunosuppression, and respiratory failure. Co-infections of SARS-CoV-2 with HIV and
    Mesh-Begriff(e) Humans ; Acquired Immunodeficiency Syndrome/epidemiology ; COVID-19 ; HIV ; Coinfection/epidemiology ; Pandemics ; Post-Acute COVID-19 Syndrome ; SARS-CoV-2 ; Tuberculosis/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2023-01-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1104828
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel: Pathogen-Induced Epigenetic Modifications in Cancers: Implications for Prevention, Detection and Treatment of Cancers in Africa.

    Djomkam Zune, Alexandra Lindsey / Olwal, Charles Ochieng' / Tapela, Kesego / Owoicho, Oloche / Nganyewo, Nora Nghochuzie / Lyko, Frank / Paemka, Lily

    Cancers

    2021  Band 13, Heft 23

    Abstract: Cancer is a major public health burden worldwide. Tumor formation is caused by multiple intrinsic and extrinsic factors. Many reports have demonstrated a positive correlation between the burden of infectious pathogens and the occurrence of cancers. ... ...

    Abstract Cancer is a major public health burden worldwide. Tumor formation is caused by multiple intrinsic and extrinsic factors. Many reports have demonstrated a positive correlation between the burden of infectious pathogens and the occurrence of cancers. However, the mechanistic link between pathogens and cancer development remains largely unclear and is subject to active investigations. Apart from somatic mutations that have been widely linked with various cancers, an appreciable body of knowledge points to alterations of host epigenetic patterns as key triggers for cancer development. Several studies have associated various infectious pathogens with epigenetic modifications. It is therefore plausible to assume that pathogens induce carcinogenesis via alteration of normal host epigenetic patterns. Thus, Africa with its disproportionate burden of infectious pathogens is threatened by a dramatic increase in pathogen-mediated cancers. To curb the potential upsurge of such cancers, a better understanding of the role of tropical pathogens in cancer epigenetics could substantially provide resources to improve cancer management among Africans. Therefore, this review discusses cancer epigenetic studies in Africa and the link between tropical pathogens and cancer burden. In addition, we discuss the potential mechanisms by which pathogens induce cancers and the opportunities and challenges of tropical pathogen-induced epigenetic changes for cancer prevention, detection and management.
    Sprache Englisch
    Erscheinungsdatum 2021-12-01
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13236051
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel ; Online: Parallels in Sepsis and COVID-19 Conditions: Implications for Managing Severe COVID-19.

    Olwal, Charles Ochieng' / Nganyewo, Nora Nghuchuzie / Tapela, Kesego / Djomkam Zune, Alexandra Lindsey / Owoicho, Oloche / Bediako, Yaw / Duodu, Samuel

    Frontiers in immunology

    2021  Band 12, Seite(n) 602848

    Abstract: Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to infection. Sepsis is a global burden killing ~11 million persons annually. In December 2019, a novel pneumonia condition termed coronavirus disease 2019 (COVID-19) ...

    Abstract Sepsis is a life-threatening systemic illness attributed to a dysregulated host response to infection. Sepsis is a global burden killing ~11 million persons annually. In December 2019, a novel pneumonia condition termed coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged and has resulted in more than 1,535,982 deaths globally as of 8
    Mesh-Begriff(e) Animals ; COVID-19/diagnosis ; COVID-19/therapy ; Cytokine Release Syndrome ; Humans ; Hypovolemia ; Immune Tolerance ; Respiratory Insufficiency ; SARS-CoV-2/physiology ; Sepsis/diagnosis ; Sepsis/therapy ; Thrombosis
    Sprache Englisch
    Erscheinungsdatum 2021-02-03
    Erscheinungsland Switzerland
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.602848
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  6. Artikel ; Online: Knowledge, attitude and perception of West Africans towards COVID-19: a survey to inform public health intervention.

    Udoakang, Aniefiok John / Djomkam Zune, Alexandra Lindsey / Tapela, Kesego / Owoicho, Oloche / Fagbohun, Ifeoluwa Kayode / Anyigba, Claudia Adzo / Lowe, Mat / Nganyewo, Nora Nghochuzie / Keneme, Bineta / Olisaka, Frances Ngozi / Henry-Ajala, Agatha Nkem / Oboh, Mary Aigbiremo / Paemka, Lily / Amenga-Etego, Lucas N

    BMC public health

    2022  Band 22, Heft 1, Seite(n) 445

    Abstract: Background: The first case of the novel coronavirus disease-2019 (COVID-19) in West Africa was first confirmed in Nigeria in February 2020. Since then, several public health interventions and preventive measures have been implemented to curtail ... ...

    Abstract Background: The first case of the novel coronavirus disease-2019 (COVID-19) in West Africa was first confirmed in Nigeria in February 2020. Since then, several public health interventions and preventive measures have been implemented to curtail transmission of the causative agent, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Therefore, this study was performed to assess the knowledge, attitudes, and perceptions of West Africans towards COVID-19.
    Methods: An online survey was conducted between 29 September to 29 October 2020 among West Africans. Thirty-three survey questions were designed to collect sociodemographic data and participants' knowledge, attitude and perception towards COVID-19. The study targeted all West African nationals who were 18 years and above, and willing to participate in the study. Participants were either in-country or abroad.
    Results: Overall, 1106 respondents (≥18 years) from 16 West African countries, with about 12.1% of them residing outside the West African subregion, participated in the survey. The respondents had an average COVID-19 knowledge score of 67.82 ± 8.31, with knowledge of the disease significantly associated with the country of residence (p = 0.00) and marginally (p = 0.05) so with settlement types (i.e., urban, suburban and rural areas). Most respondents (93.4%) could identify the main COVID-19 symptoms, and 73.20% would consult a healthcare professional if infected with SARS-CoV-2. Also, 75.2% of the respondents are willing to receive the COVID-19 vaccine, whereas 10.40% and 14.40% are unwilling and undecided, respectively. Perceptions of what constitute COVID-19 preventive measures were highly variable. Approximately, 8% of the respondents felt that their government responded excellently in managing the pandemic while a third felt that the response was just good. Also, more than half (54%) opined that isolation and treatment of COVID-19 patients is a way of curbing SARS-CoV-2 spread.
    Conclusions: Most West Africans have basic knowledge of COVID-19 and showed a positive attitude, with likely proactive practice towards the disease. However, results showed that these varied across countries and are influenced by the types of settlements. Therefore, the health and education authorities in various countries should develop focused measures capturing people in different settlements to improve their preventative measures when designing public health interventions for COVID-19 and any future epidemics or pandemics.
    Mesh-Begriff(e) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Health Knowledge, Attitudes, Practice ; Humans ; Perception ; Public Health ; SARS-CoV-2 ; Surveys and Questionnaires
    Chemische Substanzen COVID-19 Vaccines
    Sprache Englisch
    Erscheinungsdatum 2022-03-05
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-022-12814-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  7. Artikel ; Online: Non-autoimmune diabetes mellitus and the risk of virus infections: a systematic review and meta-analysis of case-control and cohort studies.

    Lontchi-Yimagou, Eric / Feutseu, Charly / Kenmoe, Sebastien / Djomkam Zune, Alexandra Lindsey / Kinyuy Ekali, Solange Fai / Nguewa, Jean Louis / Choukem, Siméon Pierre / Mbanya, Jean Claude / Gautier, Jean Francois / Sobngwi, Eugene

    Scientific reports

    2021  Band 11, Heft 1, Seite(n) 8968

    Abstract: A significant number of studies invoked diabetes as a risk factor for virus infections, but the issue remains controversial. We aimed to examine whether non-autoimmune diabetes mellitus enhances the risk of virus infections compared with the risk in ... ...

    Abstract A significant number of studies invoked diabetes as a risk factor for virus infections, but the issue remains controversial. We aimed to examine whether non-autoimmune diabetes mellitus enhances the risk of virus infections compared with the risk in healthy individuals without non-autoimmune diabetes mellitus. In this systematic review and meta-analysis, we assessed case-control and cohort studies on the association between non-autoimmune diabetes and viruses. We searched PubMed, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and Web of Science with no language restriction, to identify articles published until February 15, 2021. The main outcome assessment was the risk of virus infection in individuals with non-autoimmune diabetes. We used a random-effects model to pool individual studies and assessed heterogeneity (I
    Mesh-Begriff(e) Case-Control Studies ; Cohort Studies ; Diabetes Complications ; Humans ; Risk Factors ; Virus Diseases/complications
    Sprache Englisch
    Erscheinungsdatum 2021-04-26
    Erscheinungsland England
    Dokumenttyp Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-88598-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Zum Seitenanfang