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  1. Article ; Online: Umgang mit COVID-19 in der Notaufnahme : Erfahrungsbericht der interdisziplinären Notaufnahme des Universitätsklinikums Münster.

    Wennmann, D O / Dlugos, C P / Hofschröer, A / Hennies, M / Kühn, J / Hafezi, W / Kampmeier, S / Mellmann, A / Triphaus, S / Sackarnd, J / Tepasse, P / Keller, M / Van Aken, H / Pavenstädt, H / Kümpers, P

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2020  Volume 115, Issue 5, Page(s) 380–387

    Abstract: With the COVID-19 pandemic, emergency rooms are faced with major challenges because they act as the interface between outpatient and inpatient care. The dynamics of the pandemic forced emergency care at the University Hospital Münster to extensively ... ...

    Title translation Handling of COVID-19 in the emergency department : Field report of the emergency ward of the University Hospital Münster.
    Abstract With the COVID-19 pandemic, emergency rooms are faced with major challenges because they act as the interface between outpatient and inpatient care. The dynamics of the pandemic forced emergency care at the University Hospital Münster to extensively adjust their processes, which had to be carried out in the shortest time possible. This included the establishment of an outpatient coronavirus test center and a medical student-operated telephone hotline. Inside the hospital, new isolation capacities in the emergency room and a dedicated COVID-19 ward were set up. The patient flow was reorganized using flow diagrams for both the outpatient and inpatient areas. The general and special emergency management was optimized for the efficient treatment of COVID-19-positive patients and the staff were trained in the use of protective equipment. This report of our experience is intended to support other emergency departments in their preparation for the COVID-19 pandemic.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Emergency Medical Services ; Emergency Service, Hospital ; Humans ; Pandemics ; Patient Isolation ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Triage
    Keywords covid19
    Language German
    Publishing date 2020-04-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-020-00693-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: CC chemokine receptor 10 cell surface presentation in melanocytes is regulated by the novel interaction partner S100A10.

    Hessner, F / Dlugos, C P / Chehab, T / Schaefer, C / Homey, B / Gerke, V / Weide, T / Pavenstädt, H / Rescher, U

    Scientific reports

    2016  Volume 6, Page(s) 22649

    Abstract: The superfamily of G-protein-coupled receptors (GPCR) conveys signals in response to various endogenous and exogenous stimuli. Consequently, GPCRs are the most important drug targets. CCR10, the receptor for the chemokines CCL27/CTACK and CCL28/MEC, ... ...

    Abstract The superfamily of G-protein-coupled receptors (GPCR) conveys signals in response to various endogenous and exogenous stimuli. Consequently, GPCRs are the most important drug targets. CCR10, the receptor for the chemokines CCL27/CTACK and CCL28/MEC, belongs to the chemokine receptor subfamily of GPCRs and is thought to function in immune responses and tumour progression. However, there is only limited information on the intracellular regulation of CCR10. We find that S100A10, a member of the S100 family of Ca(2+) binding proteins, binds directly to the C-terminal cytoplasmic tail of CCR10 and that this interaction regulates the CCR10 cell surface presentation. This identifies S100A10 as a novel interaction partner and regulator of CCR10 that might serve as a target for therapeutic intervention.
    MeSH term(s) Annexin A2/metabolism ; Cell Line, Tumor ; Gene Expression Regulation ; Humans ; Melanocytes/metabolism ; Membrane Proteins/metabolism ; Protein Binding ; Protein Interaction Mapping ; Receptors, CCR10/metabolism ; S100 Proteins/metabolism
    Chemical Substances Annexin A2 ; CCR10 protein, human ; Membrane Proteins ; Receptors, CCR10 ; S100 Proteins ; S100 calcium binding protein A10
    Language English
    Publishing date 2016-03-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep22649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Umgang mit COVID-19 in der Notaufnahme : Erfahrungsbericht der interdisziplinären Notaufnahme des Universitätsklinikums Münster./ [Handling of COVID-19 in the emergency department : Field report of the emergency ward of the University Hospital Münster]

    Wennmann, D O / Dlugos, C P / Hofschröer, A / Hennies, M / Kühn, J / Hafezi, W / Kampmeier, S / Mellmann, A / Triphaus, S / Sackarnd, J / Tepasse, P / Keller, M / Van Aken, H / Pavenstädt, H / Kümpers, P

    Med Klin Intensivmed Notfmed

    Abstract: With the COVID-19 pandemic, emergency rooms are faced with major challenges because they act as the interface between outpatient and inpatient care. The dynamics of the pandemic forced emergency care at the University Hospital Münster to extensively ... ...

    Abstract With the COVID-19 pandemic, emergency rooms are faced with major challenges because they act as the interface between outpatient and inpatient care. The dynamics of the pandemic forced emergency care at the University Hospital Münster to extensively adjust their processes, which had to be carried out in the shortest time possible. This included the establishment of an outpatient coronavirus test center and a medical student-operated telephone hotline. Inside the hospital, new isolation capacities in the emergency room and a dedicated COVID-19 ward were set up. The patient flow was reorganized using flow diagrams for both the outpatient and inpatient areas. The general and special emergency management was optimized for the efficient treatment of COVID-19-positive patients and the staff were trained in the use of protective equipment. This report of our experience is intended to support other emergency departments in their preparation for the COVID-19 pandemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #102305
    Database COVID19

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  4. Article ; Online: Umgang mit COVID-19 in der Notaufnahme ; Erfahrungsbericht der interdisziplinären Notaufnahme des Universitätsklinikums Münster

    Wennmann, D. O. / Dlugos, C. P. / Hofschröer, A. / Hennies, M. / Kühn, J. / Hafezi, W. / Kampmeier, S. / Mellmann, A. / Triphaus, S. / Sackarnd, J. / Tepasse, P. / Keller, M. / Van Aken, H. / Pavenstädt, H. / Kümpers, P.

    Medizinische Klinik - Intensivmedizin und Notfallmedizin

    2020  Volume 115, Issue 5, Page(s) 380–387

    Keywords Internal Medicine ; Critical Care and Intensive Care Medicine ; Emergency ; Emergency Medicine ; covid19
    Language German
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ISSN 2193-6218
    DOI 10.1007/s00063-020-00693-0
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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