LIVIVO - Search results -

Search results

Result 1 - 10 of total 10

Search options

Article ; Online: Anatomic characteristics and novel transplantation model of the canine uterus.

Do, Xuan-Hai / Tong, Thanh-Hai / Nguyen, Trung-Chuc / Ngo, Tuan-Anh / Tran, Minh-Trang Thi

Korean journal of transplantation

2023 Volume 37, Issue 2, Page(s) 109–117

Abstract: Background: In Vietnam, the rate of absolute uterine factor infertility is increasing, but no study has been published on uterine transplantation. The present study was designed to comprehensively observe the canine uterine anatomy and to examine the ... ...

Abstract	Background: In Vietnam, the rate of absolute uterine factor infertility is increasing, but no study has been published on uterine transplantation. The present study was designed to comprehensively observe the canine uterine anatomy and to examine the possibility of using a living canine donor for uterine transplantation training and further research. Methods: Ten female Vietnamese mixed-breed dogs were sacrificed for anatomical research, and 15 additional pairs were used to evaluate the novel uterine transplant model. Results: The anatomic features of the canine uterus differed considerably from those of the human uterus, with the uterine vessels originating from branches of the pudendal vessels (also known as the vaginal vessels). The uterine vascular pedicle had a small diameter (1 to 1.5 mm for arteries and 1.2 to 2.0 mm for veins) and required manipulation under a microscope. To perform uterine transplantation, the donor specimen's artery and vein lengths were successfully reconstructed by anastomosis between both sides of the vasculature using autologous Y-shaped subcutaneous veins. The living-donor uterine transplantation model constructed in this study was feasible, with the transplanted uterus surviving in 86.7% of cases (13/15). Conclusions: Uterine transplantation was successfully performed in a Vietnamese canine living donor model. This model could be helpful in uterine transplantation training and improve the transplantation success rate in humans.
Language	English
Publishing date	2023-05-25
Publishing country	Korea (South)
Document type	Journal Article
ISSN	2671-8804
ISSN (online)	2671-8804
DOI	10.4285/kjt.23.0019
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Regulation and therapeutic potentials of microRNAs to non-small cell lung cancer.

Le, Mai Thi / Nguyen, Huyen-Thu / Nguyen, Xuan-Hung / Do, Xuan-Hai / Mai, Binh Thanh / Ngoc Nguyen, Ha Thi / Trang Than, Uyen Thi / Nguyen, Thanh-Hong

Heliyon

2023 Volume 9, Issue 11, Page(s) e22080

Abstract: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80%-85% of total cases and leading to millions of deaths worldwide. Drug resistance is the primary cause of treatment failure in NSCLC, which urges scientists to ... ...

Abstract	Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80%-85% of total cases and leading to millions of deaths worldwide. Drug resistance is the primary cause of treatment failure in NSCLC, which urges scientists to develop advanced approaches for NSCLC treatment. Among novel approaches, the miRNA-based method has emerged as a potential approach as it allows researchers to modulate target gene expression. Subsequently, cell behaviors are altered, which leads to the death and the depletion of cancer cells. It has been reported that miRNAs possess the capacity to regulate multiple genes that are involved in various signaling pathways, including the phosphoinositide 3-kinase, receptor tyrosine kinase/rat sarcoma virus/mitogen-activated protein kinase, wingless/integrated, retinoblastoma, p53, transforming growth factor β, and nuclear factor-kappa B pathways. Dysregulation of these signaling pathways in NSCLC results in abnormal cell proliferation, tissue invasion, and drug resistance while inhibiting apoptosis. Thus, understanding the roles of miRNAs in regulating these signaling pathways may enable the development of novel NSCLC treatment therapies. However, a comprehensive review of potential miRNAs in NSCLC treatment has been lacking. Therefore, this review aims to fill the gap by summarizing the up-to-date information on miRNAs regarding their targets, impact on cancer-associated pathways, and prospective outcomes in treating NSCLC. We also discuss current technologies for delivering miRNAs to the target cells, including virus-based, non-viral, and emerging extracellular vesicle-based delivery systems. This knowledge will support future studies to develop an innovative miRNA-based therapy and select a suitable carrier to treat NSCLC effectively.
Language	English
Publishing date	2023-11-14
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e22080
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Detection of sFas, sCD137, and IL-27 Cytokines as Potential Biomarkers for Hepatocellular Carcinoma Diagnosis.

Do, Xuan-Hai / Le, Mai Thi / Nguyen, Thu Huyen / Le, Thanh Thien / Nguyen, Xuan-Hung / Mai, Thanh Binh / Hoang, Thi My Nhung / Than, Uyen Thi Trang

Journal of hepatocellular carcinoma

2023 Volume 10, Page(s) 783–793

Abstract: Purpose: Hepatocellular carcinoma (HCC), a prevalent type of liver cancer, is mainly diagnosed in the advanced stage, leading to a high mortality rate. Recent advances have identified peripheral cytokines as a potential tool to predict disease outcomes ... ...

Abstract	Purpose: Hepatocellular carcinoma (HCC), a prevalent type of liver cancer, is mainly diagnosed in the advanced stage, leading to a high mortality rate. Recent advances have identified peripheral cytokines as a potential tool to predict disease outcomes and inform therapeutic decisions. Hence, in this study, we aim to build a predictive model for HCC based on serum levels of different cytokines. Patients and methods: We used immunoassay to quantify the concentrations of IL-27, MIP-1β, Perforin, sCD137, sFas, and TNF-α in the serum of 38 HCC patients and 15 healthy controls. Logistic regression was then used to construct classification models detecting HCC based on these cytokines. A nomogram of the best-performing model was generated to visualize HCC prediction. Results: sFas and MIP-1β were found to be significantly higher in HCC patients compared to controls. Predictive models based on cytokine levels combining sFas, sCD137, and IL-27 performed the best in distinguishing HCC patients from healthy controls. This model has a bias-corrected area under the receiver operating characteristic (ROC) curve (AUC) of 0.948, a sensitivity of 92.11%, a specificity of 93.33%, and an accuracy of 0.925. Conclusion: Our findings suggest that serum cytokines have the potential to be utilized in HCC screening to improve detection rates.
Language	English
Publishing date	2023-05-26
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2780784-8
ISSN	2253-5969
ISSN	2253-5969
DOI	10.2147/JHC.S409649
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: High Biocompatibility, MRI Enhancement, and Dual Chemo- and Thermal-Therapy of Curcumin-Encapsulated Alginate/Fe

Do, Xuan-Hai / Nguyen, Tu Dac / Le, Thi Thu Huong / To, Thuy Thanh / Bui, Thi Van Khanh / Pham, Nam Hong / Lam, Khanh / Hoang, Thi My Nhung / Ha, Phuong Thu

Pharmaceutics

2023 Volume 15, Issue 5

Abstract: 1) Background: Magnetite ( ... ...

Abstract	(1) Background: Magnetite (Fe
Language	English
Publishing date	2023-05-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15051523
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effects of Extracellular Vesicles Secreted by TGFβ-Stimulated Umbilical Cord Mesenchymal Stem Cells on Skin Fibroblasts by Promoting Fibroblast Migration and ECM Protein Production

Duc Minh Vu / Van-Tinh Nguyen / Thu Huyen Nguyen / Phuong Thi Xuan Do / Huy Hoang Dao / Do Xuan Hai / Nhi Thi Le / Xuan-Hung Nguyen / Uyen Thi Trang Than

Biomedicines, Vol 10, Iss 8, p

2022 Volume 1810

Abstract: Umbilical cord-derived mesenchymal stem cells (UCMSCs) have been illustrated for their roles in immunological modulation and tissue regeneration through the secretome. Additionally, culture conditions can trigger the secretion of extracellular vesicles ( ... ...

Abstract	Umbilical cord-derived mesenchymal stem cells (UCMSCs) have been illustrated for their roles in immunological modulation and tissue regeneration through the secretome. Additionally, culture conditions can trigger the secretion of extracellular vesicles (EVs) into extracellular environments with significant bioactivities. This study aims to investigate the roles of three EV sub-populations released by UCMSCs primed with transforming growth factor β (TGFβ) and their capacity to alter dermal fibroblast functions for skin aging. Results show that three EV sub-populations, including apoptotic bodies (ABs), microvesicles (MVs), and exosomes (EXs), were separated from conditioned media. These three EVs carried growth factors, such as FGF-2, HGF, and VEGF-A, and did not express noticeable effects on fibroblast proliferation and migration. Only EX from TGFβ-stimulated UCMSCs exhibited a better capacity to promote fibroblasts migrating to close scratched wounds than EX from UCMSCs cultured in the normal condition from 24 h to 52 h. Additionally, mRNA levels of ECM genes (COL I, COL III, Elastin, HAS II, and HAS III) were detected with lower levels in fibroblasts treated with EVs from normal UCMSCs or TGFβ-stimulated UCMSCs compared to EV-depleted condition. On the contrary, the protein levels of total collagen and elastin released by fibroblasts were greater in the cell groups treated with EVs compared to EV-depleted conditions; particularly elastin associated with TGFβ-stimulated UCMSCs. These data indicate the potential roles of EVs from UCMSCs in protecting skin from aging by promoting ECM protein production.
Keywords	umbilical cord-derived ; extracellular vesicles ; mesenchymal stem cells ; skin rejuvenation ; fibroblast migration ; fibroblast proliferation ; Biology (General) ; QH301-705.5
Subject code	571
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: High biocompatible FITC-conjugated silica nanoparticles for cell labeling in both in vitro and in vivo models.

Nguyen, Thi Thuy / Nguyen, Hoang Nam / Nghiem, Thi Ha Lien / Do, Xuan-Hai / To, Thanh Thuy / Do, Thi Xuan Phuong / Do, Dieu Linh / Nguyen, Huong Giang / Nguyen, Huy Manh / Nguyen, Ngoc Dinh / Luu, Manh Quynh / Nguyen, Trong Nghia / Nguyen, Thi Bich Ngoc / Nguyen, Van Toan / Pham, Van Thanh / Than, Uyen Thi Trang / Hoang, Thi My Nhung

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6969

Abstract: Fluorescence nanosilica-based cell tracker has been explored and applied in cell biological research. However, the aggregation of these nanoparticles at physiological pH is still the main limitation. In this research, we introduced a novel fluorescence ... ...

Abstract	Fluorescence nanosilica-based cell tracker has been explored and applied in cell biological research. However, the aggregation of these nanoparticles at physiological pH is still the main limitation. In this research, we introduced a novel fluorescence nano-based cell tracker suitable for application in live cells. The silica-coated fluorescein isothiocyanate isomer (FITC-SiO
MeSH term(s)	Animals ; Humans ; HeLa Cells ; Fluorescein-5-isothiocyanate ; Silicon Dioxide/chemistry ; Endothelial Cells ; Nanoparticles/toxicity ; Nanoparticles/chemistry
Chemical Substances	Fluorescein-5-isothiocyanate (I223NX31W9) ; Silicon Dioxide (7631-86-9)
Language	English
Publishing date	2024-03-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-55600-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Cytokine-primed umbilical cord mesenchymal stem cells enhanced therapeutic effects of extracellular vesicles on osteoarthritic chondrocytes.

Nguyen, Thu Huyen / Dao, Huy Hoang / Duong, Chau Minh / Nguyen, Xuan-Hung / Hoang, Diem Huong / Do, Xuan-Hai / Truong, Trung Quang / Nguyen, Tu Dac / Nguyen, Liem Thanh / Than, Uyen Thi Trang

Frontiers in immunology

2022 Volume 13, Page(s) 1041592

Abstract: In recent years, extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) have emerged as a potential cell-free therapy against osteoarthritis (OA). Thus, we investigated the therapeutic effects of EVs released by cytokine-primed umbilical ... ...

Abstract	In recent years, extracellular vesicles (EVs) secreted by mesenchymal stem cells (MSCs) have emerged as a potential cell-free therapy against osteoarthritis (OA). Thus, we investigated the therapeutic effects of EVs released by cytokine-primed umbilical cord-derived MSCs (UCMSCs) on osteoarthritic chondrocyte physiology. Priming UCMSCs individually with transforming growth factor beta (TGFβ), interferon alpha (IFNα), or tumor necrosis factor alpha (TNFα) significantly reduced the sorting of miR-181b-3p but not miR-320a-3p; two negative regulators of chondrocyte regeneration, into EVs. However, the EV treatment did not show any significant effect on chondrocyte proliferation. Meanwhile, EVs from both non-priming and cytokine-primed UCMSCs induced migration at later time points of measurement. Moreover, TGFβ-primed UCMSCs secreted EVs that could upregulate the expression of chondrogenesis markers (
MeSH term(s)	Humans ; Chondrocytes/metabolism ; Cytokines/metabolism ; Extracellular Vesicles/metabolism ; Umbilical Cord/pathology ; Mesenchymal Stem Cells/metabolism ; Osteoarthritis/metabolism ; Transforming Growth Factor beta/metabolism
Chemical Substances	Cytokines ; Transforming Growth Factor beta
Language	English
Publishing date	2022-10-27
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2022.1041592
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Differential Cytotoxicity of Curcumin-Loaded Micelles on Human Tumor and Stromal Cells.

Do, Xuan-Hai / Hoang, My Hanh Thi / Vu, Anh-Tuan / Nguyen, Lai-Thanh / Bui, Dung Thi Thuy / Dinh, Duy-Thanh / Nguyen, Xuan-Hung / Than, Uyen Thi Trang / Mai, Hien Thi / To, Thuy Thanh / Nguyen, Tra Ngoc Huong / Hoang, Nhung Thi My

International journal of molecular sciences

2022 Volume 23, Issue 20

Abstract: Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. This study evaluated the toxicity ... ...

Abstract	Although curcumin in the form of nanoparticles has been demonstrated as a potential anti-tumor compound, the impact of curcumin and nanocurcumin in vitro on normal cells and in vivo in animal models is largely unknown. This study evaluated the toxicity of curcumin-loaded micelles in vitro and in vivo on several tumor cell lines, primary stromal cells, and zebrafish embryos. Breast tumor cell line (MCF7) and stromal cells (human umbilical cord vein endothelial cells, human fibroblasts, and human umbilical cord-derived mesenchymal stem cells) were used in this study. A zebrafish embryotoxicity (FET) assay was conducted following the Organisation for Economic Co-operation and Development (OECD) Test 236. Compared to free curcumin, curcumin PM showed higher cytotoxicity to MCF7 cells in both monolayer culture and multicellular tumor spheroids. The curcumin-loaded micelles efficiently penetrated the MCF7 spheroids and induced apoptosis. The nanocurcumin reduced the viability and disturbed the function of stromal cells by suppressing cell migration and tube formation. The micelles demonstrated toxicity to the development of zebrafish embryos. Curcumin-loaded micelles demonstrated toxicity to both tumor and normal primary stromal cells and zebrafish embryos, indicating that the use of nanocurcumin in cancer treatment should be carefully investigated and controlled.
MeSH term(s)	Animals ; Humans ; Micelles ; Curcumin/pharmacology ; Zebrafish ; Endothelial Cells ; Antineoplastic Agents/pharmacology ; Cell Line, Tumor ; Stromal Cells ; Drug Carriers
Chemical Substances	Micelles ; Curcumin (IT942ZTH98) ; Antineoplastic Agents ; Drug Carriers
Language	English
Publishing date	2022-10-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms232012362
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Book: Nét phá trong chế tác non bộ

Đỗ, Xuân Hải

1996

Title variant	Nét phá trong non bộ ; Chế tác non bộ
Author's details	Đỗ Xuân Hải
Keywords	Bonsai
Language	Vietnamese
Size	140, [12] p. of plates :, ill. ;, 20 cm.
Edition	Tái bản lần thứ nhất.
Publisher	Thành Phố Hồ Chí Minh
Publishing place	Tp. Hồ Chí Minh
Document type	Book
Database	NAL-Catalogue (AGRICOLA)

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Book: Tiểu cảnh

Đỗ, Xuân Hải

Punchung

1995

Title variant	Punchung
Author's details	Đỗ Xuân Hải
Keywords	Bonsai
Language	Vietnamese
Size	152, [12] p. of plates :, ill. ;, 20 cm.
Publisher	Thành Phố Hồ Chí Minh
Publishing place	Tp. Hồ Chí Minh
Document type	Book
Database	NAL-Catalogue (AGRICOLA)

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Inter-library loan at ZB MED