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Article: Is it possible to anchor a tooth with photobiomodulation?

Dominguez, Angela

World journal of clinical cases

2024 Volume 12, Issue 5, Page(s) 872–874

Abstract: During orthodontic treatment, we can achieve differential movements by using photobiomodulation (PBM) as an adjuvant before applying force. We can expect a greater bone density that initially resists movement while applying PBM to the other teeth to ... ...

Abstract	During orthodontic treatment, we can achieve differential movements by using photobiomodulation (PBM) as an adjuvant before applying force. We can expect a greater bone density that initially resists movement while applying PBM to the other teeth to achieve an accelerating effect. The proposed protocol is to use an 810 nm laser at 0.1W power, applying between 4 and 6J per tooth for 22 s on the vestibular and lingual root surfaces, following the axial axis of the tooth. The energy density depends on the tip selected in the instrument. Normal bone remodeling cannot be avoided by applying high doses of PBM. PBM should be applied before orthodontic force to reduce tooth movement. In addition, PBM can be used during force application to teeth that require acceleration to achieve differential movement in orthodontic treatments. The protocol is the same in both scenarios.
Language	English
Publishing date	2024-01-29
Publishing country	United States
Document type	Editorial
ISSN	2307-8960
ISSN	2307-8960
DOI	10.12998/wjcc.v12.i5.872
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Article: Current protocol to achieve dental movement acceleration and pain control with Photo-biomodulation.

Dominguez, Angela

World journal of methodology

2023 Volume 13, Issue 5, Page(s) 379–383

Abstract: When designing a study on dental movement acceleration or pain control during orthodontic treatment, it is crucial to consider effective parameters. The objective of this editorial is to compile the most effective parameters supported by evidence that ... ...

Abstract	When designing a study on dental movement acceleration or pain control during orthodontic treatment, it is crucial to consider effective parameters. The objective of this editorial is to compile the most effective parameters supported by evidence that should be considered in future studies to achieve complete parameter homogenization. The protocol currently recommended to homogenize the parameters and facilitate the development of further meta-analysis in terms of acceleration of movement and pain control in orthodontics is Wavelength: 810 nm, 2.2 J per surface, 0.1 W in continuous mode/0.1 W average power in a super-pulsed, sweeping movement, 1mm from the mucosa, 22 seconds along the vestibular surface and 22 seconds along the lingual surface, the recommended speed of movement is 2 mm/sec, 1 application during each orthodontic control, to achieve dental movement acceleration and repeat the dose at 24 h to ensure pain elimination. The energy density and power density will depend on the spot size used in the equipment and the distance from the mucosa. It will strengthen the evidence of photobiomodulation as the best therapy to accelerate tooth movement and at the same time control the pain produced by orthodontic treatments.
Language	English
Publishing date	2023-12-20
Publishing country	United States
Document type	Editorial
ISSN	2222-0682
ISSN	2222-0682
DOI	10.5662/wjm.v13.i5.379
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Article ; Online: Interrogating the 5'UTR tandem repeats of retrotransposon roo of Drosophila about horizontal transfer.

Domínguez, Ana

Genetica

2021 Volume 149, Issue 3, Page(s) 171–177

Abstract: Horizontal transfer in Drosophila has been inferred for several families of transposable elements. Specifically, the retroelement roo has been suggested to have been horizontally transferred between the species D. melanogaster, D. simulans, D. sechellia ... ...

Abstract	Horizontal transfer in Drosophila has been inferred for several families of transposable elements. Specifically, the retroelement roo has been suggested to have been horizontally transferred between the species D. melanogaster, D. simulans, D. sechellia and D. yakuba. The inferences were based on the observation that divergence between transposable elements in different species was lower than the divergence found in typical nuclear genes and in the incongruence of phylogenies of the species and their TEs. Here, we address the question of the possible horizontal transfer of roo between species of the Drosophila genus by studying the presence absence of a duplication of 99 bp in the 5'UTR of the transposon, as well as comparing the sequences of the paralogous and orthologous duplicated repeats within and between species. First, the repeats were only found in five species of the melanogaster subgroup. Second, the date of occurrence of the duplication event originating the repeats was posterior to the split of the subgroup. The duplication date suggests an origin previous to the split of D. simulans and D. sechellia and close to the divergence of D. melanogaster from the D. simulans complex. These data point to horizontal transfer to the afrotropical species D. yakuba and D. erecta from one of the cosmopolitan species D. melanogaster or D. simulans. We propose that the parasitoid wasp Leptopilina could have been the vector of horizontal transfer after the observation that a sequence of 845 bp with high homology to a fragment of roo was isolated from this wasp.
MeSH term(s)	5' Untranslated Regions ; Animals ; Drosophila melanogaster ; Evolution, Molecular ; Gene Duplication ; Gene Transfer, Horizontal ; Retroelements/genetics ; Tandem Repeat Sequences
Chemical Substances	5' Untranslated Regions ; Retroelements
Language	English
Publishing date	2021-04-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2165-9
ISSN	1573-6857 ; 0016-6707
ISSN (online)	1573-6857
ISSN	0016-6707
DOI	10.1007/s10709-021-00120-y
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Article ; Online: Complications after abdominal surgery.

de Araújo Martins-Romeo, D / Rivera Domínguez, A

Radiologia

2023 Volume 65 Suppl 1, Page(s) S99–S108

Abstract: Complications after abdominal surgery are often seen in emergency departments. Many postoperative complications (e.g., infections, abscesses, hematomas, and active bleeding) are common to all types of surgery; others are specific to different types of ... ...

Abstract	Complications after abdominal surgery are often seen in emergency departments. Many postoperative complications (e.g., infections, abscesses, hematomas, and active bleeding) are common to all types of surgery; others are specific to different types of surgery. Computed tomography (CT) is the technique normally used to diagnose postoperative complications. This article reviews the changes that occur after some of the most common abdominal interventions that can be mistaken for pathological processes, the findings that can be considered normal after surgical intervention, and the most common early complications. It also describes the optimal protocols for CT studies depending on the different types of complications that are suspected.
MeSH term(s)	Humans ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Tomography, X-Ray Computed
Language	English
Publishing date	2023-02-26
Publishing country	Spain
Document type	Review ; Journal Article
ISSN	2173-5107
ISSN (online)	2173-5107
DOI	10.1016/j.rxeng.2022.09.012
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Article ; Online: Diverticulosis yeyuno-ileal.

Dominguez, Andrés

Medicina

2020 Volume 80, Issue 4, Page(s) 391

Title translation	Jejunal-ileal diverticulosis.
MeSH term(s)	Diverticulum/diagnostic imaging ; Humans
Language	Spanish
Publishing date	2020-09-08
Publishing country	Argentina
Document type	Journal Article
ZDB-ID	411586-7
ISSN	1669-9106 ; 0025-7680 ; 0325-951X
ISSN (online)	1669-9106
ISSN	0025-7680 ; 0325-951X
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Article ; Online: The Utility of long-Term Number Needed to Treat to Evaluate Interleukin 17 and 23 Inhibitor Therapies in the Treatment of Moderate to Severe Plaque Psoriasis.

González-Domínguez, A / García-Agua, N / Dauden, E / Ventayol-Bosch, P

Actas dermo-sifiliograficas

2024 Volume 115, Issue 4, Page(s) 427–429

Title translation	La utilidad del número necesario de pacientes a largo plazo a tratar para evaluar las terapias inhibidoras de las interleucinas 17 y 23 en el tratamiento de la psoriasis en placas de moderada a grave.
MeSH term(s)	Humans ; Interleukin-17 ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal/pharmacology ; Ustekinumab ; Psoriasis/drug therapy ; Severity of Illness Index ; Treatment Outcome ; Interleukin-23
Chemical Substances	Interleukin-17 ; Antibodies, Monoclonal ; Ustekinumab (FU77B4U5Z0) ; Interleukin-23
Language	Spanish
Publishing date	2024-01-13
Publishing country	Spain
Document type	Case Reports
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2023.03.012
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Article ; Online: [Translated article] The Utility of long-Term Number Needed to Treat to Evaluate Interleukin 17 and 23 Inhibitor Therapies in the Treatment of Moderate to Severe Plaque Psoriasis.

González-Domínguez, A / García-Agua, N / Dauden, E / Ventayol-Bosch, P

Actas dermo-sifiliograficas

2024 Volume 115, Issue 4, Page(s) T427–T429

MeSH term(s)	Humans ; Interleukin-17 ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal/pharmacology ; Ustekinumab ; Psoriasis/drug therapy ; Treatment Outcome ; Severity of Illness Index ; Interleukin-23
Chemical Substances	Interleukin-17 ; Antibodies, Monoclonal ; Ustekinumab (FU77B4U5Z0) ; Interleukin-23
Language	Spanish
Publishing date	2024-02-07
Publishing country	Spain
Document type	Case Reports
ZDB-ID	390255-9
ISSN	1578-2190 ; 0001-7310 ; 1138-8196
ISSN (online)	1578-2190
ISSN	0001-7310 ; 1138-8196
DOI	10.1016/j.ad.2023.03.019
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Article ; Online: Molecular screening of tick-borne microorganisms in ticks from rural areas of Panama, with the first record of Ehrlichia minasensis in Rhipicephalus microplus from Central America.

Bermúdez C, Sergio E / Félix, María L / Domínguez A, Lillian / Araúz, Dimelza / Venzal, José M

Veterinary research communications

2024 Volume 48, Issue 2, Page(s) 1301–1308

Abstract: During a molecular screening of rickettsial, borrelial and protozoal agents in ticks from rural areas of Panama, we detected DNA of Rickettsia amblyommatis in four Amblyomma mixtum collected from horses in a locality in Los Santos province. Ehrlichia ... ...

Abstract	During a molecular screening of rickettsial, borrelial and protozoal agents in ticks from rural areas of Panama, we detected DNA of Rickettsia amblyommatis in four Amblyomma mixtum collected from horses in a locality in Los Santos province. Ehrlichia minasensis and Anaplasma marginale were identified from three and two Rhipicephalus microplus, respectively, collected on cows from Chiriqui province. No DNA from other tick-borne agents was found. These results increase the information of R. amblyommatis and A. marginale in Panama, and also mark the first record of E. minasensis in Central America.
MeSH term(s)	Female ; Animals ; Cattle ; Horses ; Rhipicephalus/microbiology ; Ehrlichia/genetics ; Panama/epidemiology ; Central America
Language	English
Publishing date	2024-01-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	406735-6
ISSN	1573-7446 ; 0165-7380
ISSN (online)	1573-7446
ISSN	0165-7380
DOI	10.1007/s11259-024-10306-2
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Article: Has the trend in pancreatic cancer mortality in Spain started to slow down?

Cayuela, Lucía / Cayuela Domínguez, Aurelio

Revista espanola de enfermedades digestivas

2023 Volume 116, Issue 1, Page(s) 14–21

Abstract: Introduction: the aim of this study was to describe the trends of pancreatic cancer mortality by autonomous communities (ACs) and gender in Spain (1980-2021).: Methods: an ecological trend study was performed (with aggregated data obtained from the ... ...

Abstract	Introduction: the aim of this study was to describe the trends of pancreatic cancer mortality by autonomous communities (ACs) and gender in Spain (1980-2021). Methods: an ecological trend study was performed (with aggregated data obtained from the National Institute of Statistics). Age-standardized mortality rates (ASMRs) for pancreatic cancer (per 100,000) were estimated by direct standardization, using the European standard population. Trends in ASMR (all ages and truncated 35-64 years) were analyzed by sex in each AC using a joinpoint regression model. The annual percent changes (APC) and average annual percentage of change (AAPC) were computed for trends using the joinpoint regression analysis. Results: in both sexes, ASMRs (all ages) increased significantly (p < 0.05) during the study period (AAPC: 1.5 % in males and 1.8 % in females). The joinpoint analysis identified a turning point in the trends in the late 1980s, which delineates two periods: an initial period of significant increase followed by a period of slowing of the increase (APC: 0.9 % and 1.4 % in males and females respectively; p < 0.05). In both sexes, a significant increase in ASMR (all ages) was observed in all ACs, except in Navarre, where the rates remained stable in males. In males, three ACs (Galicia, Madrid and Navarre) showed a point of inflexion in the time trend around the year 2000 (1999, 2000 and 2001 respectively), when the rates, after a period of significant increase (ACs: 2.6 %, 2.4 %, and 2.4 %, respectively; p < 0.05), stabilized (Galicia and Navarre) or the increase slowed (Madrid). In females, only Madrid showed a point of inflection in 1992, when, after a significant increase, the rates slowed down (1992-2021; APC: 1.5 %; p < 0.05). Conclusions: the upward trend in pancreatic cancer mortality in some ACs seems to have slowed (in both sexes in Madrid), stabilized (in men in Galicia and Navarre) or turned around (in men aged 30-64 in Navarre).
MeSH term(s)	Male ; Female ; Humans ; Spain/epidemiology ; Pancreatic Neoplasms ; Time Factors ; Regression Analysis
Language	English
Publishing date	2023-08-01
Publishing country	Spain
Document type	Journal Article
ZDB-ID	1070381-0
ISSN	1130-0108 ; 0212-7512
ISSN	1130-0108 ; 0212-7512
DOI	10.17235/reed.2023.9573/2023
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Article ; Online: Cost-effectiveness of the CNIC-Polypill versus separate monocomponents in cardiovascular secondary prevention in Spain.

González-Domínguez, A / Durán, A / Hidalgo-Vega, Á / Barrios, V

Revista clinica espanola

2023 Volume 223, Issue 7, Page(s) 414–422

Abstract: Introduction and objectives: Despite advances in treatment, cardiovascular disease is the second leading cause of death in Spain. The objective of this study was to determine the cost-effectiveness of the CNIC-Polypill strategy (acetylsalicylic acid 100 ...

Abstract	Introduction and objectives: Despite advances in treatment, cardiovascular disease is the second leading cause of death in Spain. The objective of this study was to determine the cost-effectiveness of the CNIC-Polypill strategy (acetylsalicylic acid 100 mg, atorvastatin 20/40 mg, ramipril 2.5/5/10 mg) compared with the same separate monocomponents for the secondary prevention of recurrent cardiovascular events in adults in Spain. Materials and methods: A Markov cost-utility model was adapted considering 4 health states (stable, subsequent major adverse cardiovascular event, subsequent ischemic stroke and death) and the SMART risk equation over a lifetime horizon from the perspective of the Spanish National Healthcare System. The CNIC-Polypill strategy was compared with monocomponents in a hypothetical cohort of 1000 secondary prevention patients. Effectiveness, epidemiological, cost and utilities data were obtained from the NEPTUNO study, official databases and literature. Outcomes were costs (in 2021 euros) per life-year (LY) and quality-adjusted LY (QALY) gained. A 3% discount rate was applied. Deterministic one-way and probabilistic sensitivity analyses evaluated the robustness of the model. Results: The CNIC-Polypill strategy in secondary prevention results in more LY (13.22) and QALY (11.64) gains at a lower cost than monocomponents. The CNIC-Polypill is dominant and saves є280.68 per patient compared with monocomponents. The probabilistic sensitivity analysis shows that 82.4% of the simulations are below the threshold of є25,000 per QALY gained. Conclusions: The CNIC-Polypill strategy in secondary cardiovascular prevention is cost-effective compared with the same separate monocomponents, resulting in a cost-saving strategy to the Spanish National Healthcare System.
MeSH term(s)	Adult ; Humans ; Cost-Benefit Analysis ; Secondary Prevention/methods ; Spain ; Atorvastatin ; Aspirin/therapeutic use ; Ramipril/therapeutic use ; Cardiovascular Diseases/prevention & control ; Quality-Adjusted Life Years
Chemical Substances	Atorvastatin (A0JWA85V8F) ; Aspirin (R16CO5Y76E) ; Ramipril (L35JN3I7SJ)
Language	English
Publishing date	2023-06-21
Publishing country	Spain
Document type	Journal Article
ISSN	2254-8874
ISSN (online)	2254-8874
DOI	10.1016/j.rceng.2023.06.007
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