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Article ; Online: Design and Analysis of Systematic Batched Network Codes.

Mao, Licheng / Yang, Shenghao / Huang, Xuan / Dong, Yanyan

2023 Volume 25, Issue 7

Abstract: Systematic codes are of important practical interest for communications. Network coding, however, seems to conflict with systematic codes: although the source node can transmit message packets, network coding at the intermediate network nodes may ... ...

Abstract	Systematic codes are of important practical interest for communications. Network coding, however, seems to conflict with systematic codes: although the source node can transmit message packets, network coding at the intermediate network nodes may significantly reduce the number of message packets received by the destination node. Is it possible to obtain the benefit of network coding while preserving some properties of the systematic codes? In this paper, we study the systematic design of batched network coding, which is a general network coding framework that includes random linear network coding as a special case. A batched network code has an outer code and an inner code, where the latter is formed by linear network coding. A systematic batched network code must take both the outer code and the inner code into consideration. Based on the outer code of a BATS code, which is a matrix-generalized fountain code, we propose a general systematic outer code construction that achieves a low encoding/decoding computation cost. To further reduce the number of random trials required to search a code with a close-to-optimal coding overhead, a triangular embedding approach is proposed for the construction of the systematic batches. We introduce new inner codes that provide protection for the systematic batches during transmission and show that it is possible to significantly increase the expected number of message packets in a received batch at the destination node, without harm to the expected rank of the batch transfer matrix generated by network coding.
Language	English
Publishing date	2023-07-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2014734-X
ISSN	1099-4300 ; 1099-4300
ISSN (online)	1099-4300
ISSN	1099-4300
DOI	10.3390/e25071055
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: [A Case of Multidomain Integrated Treatment Strategy  for Complex Primary Pulmonary Sarcomatoid Carcinoma].

Huo, Xiaosen / Zou, Hang / Dong, Yanyan / Li, Yuan / Bian, Lingjie / Li, Lei / Wang, Hongwu

Zhongguo fei ai za zhi = Chinese journal of lung cancer

2024 Volume 27, Issue 2, Page(s) 157–160

Abstract: Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly malignant tumor, which includes the following five pathologic types: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary blastoma. The onset of PSC ... ...

Abstract	Pulmonary sarcomatoid carcinoma (PSC) is a rare and highly malignant tumor, which includes the following five pathologic types: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary blastoma. The onset of PSC is occult with non-specific clinical symptoms and signs. The clinical manifestations include irritating cough, bloody sputum, dyspnea, chest pain and so on, which are closely related to the growth and invasion site of the tumor. PSC tends to metastasize early, so most patients are already in local advanced stage or advanced stage with a median survival of 9 months at the time of hospital visit. A patient with primary PSC which led to 90% stenosis in central airway was treated by combined method of vascular and tracheoscopic intervention in our respiratory center. This treatment prolonged the patient's survival time and got a satisfactory effect at 19-month follow-up after surgery. Herein we report the case for clinical reference. .
MeSH term(s)	Humans ; Lung Neoplasms/diagnosis ; Prognosis ; Carcinoma/pathology ; Carcinosarcoma/surgery ; Carcinosarcoma/pathology ; Lung/pathology
Language	Chinese
Publishing date	2024-03-07
Publishing country	China
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	2438672-8
ISSN	1999-6187 ; 1009-3419
ISSN (online)	1999-6187
ISSN	1009-3419
DOI	10.3779/j.issn.1009-3419.2024.102.04
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Article ; Online: Regulation of Notch Signaling Pathway to Innate Lymphoid Cells in Patients with Acute Myocardial Infarction.

Yu, Haiwen / Wei, Yongjie / Dong, Yanyan / Chen, Penglei

Immunological investigations

2022 Volume 52, Issue 2, Page(s) 241–255

Abstract: The Notch signaling pathway is an important regulator in fate decisions and immune responses of innate lymphoid cells (ILCs). However, the function of Notch signaling in ILCs in acute coronary syndrome is still not fully elucidated. Thirty-one unstable ... ...

Abstract	The Notch signaling pathway is an important regulator in fate decisions and immune responses of innate lymphoid cells (ILCs). However, the function of Notch signaling in ILCs in acute coronary syndrome is still not fully elucidated. Thirty-one unstable angina pectoris (UAP) patients, 21 acute myocardial infarction (AMI) patients, and 20 controls were included in this study. Peripheral blood mononuclear cells (PBMCs) were isolated. The mRNA expression levels of Notch receptors and ligands were measured by real-time PCR, while ILC subsets were measured by flow cytometry. Lin
MeSH term(s)	Humans ; Lymphocytes ; Immunity, Innate ; Leukocytes, Mononuclear ; Signal Transduction ; Myocardial Infarction
Language	English
Publishing date	2022-12-23
Publishing country	England
Document type	Journal Article
ZDB-ID	632565-8
ISSN	1532-4311 ; 0882-0139
ISSN (online)	1532-4311
ISSN	0882-0139
DOI	10.1080/08820139.2022.2158856
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Zs.A 988: Show issues

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Article: Fabrication of hydrophobic/oleophilic cotton fabric based on thiol–ene click reaction for oil/water separation

Liang, Liping / Dong, Yanyan / Xu, Wang / Meng, Xu

The journal of the Textile Institute. 2022 Sept. 2, v. 113, no. 9

2022

Abstract: A hydrophobic/oleophilic cotton fabric was prepared based on thiol–ene click reaction. The preparation method was simple, which consists of only two steps. Firstly, self-assembly of 3-mercaptopropyltriethoxysilane (MPTES) to modify cotton fabric, and ... ...

Abstract	A hydrophobic/oleophilic cotton fabric was prepared based on thiol–ene click reaction. The preparation method was simple, which consists of only two steps. Firstly, self-assembly of 3-mercaptopropyltriethoxysilane (MPTES) to modify cotton fabric, and then octadecyl methacrylate was further grafted on the cotton fabric surface to generate low surface free energy. The chemical structure, surface topography and wettability were characterized. The results showed the as-prepared fabric possessed hydrophobic/oleophilic properties with a water contact angle (WCA) of 150.1°, and oil contact angle (OCA) was close to 0°. In addition, it had good hydrophobic property even if after 600 cycles of friction test. Meanwhile, the as-prepared fabric could separate various types of oil/water mixtures, and these separation efficiencies were better than 94% on average. It created a new method to prepare oil/water separation fabric, which will be used in practical applications.
Keywords	Gibbs free energy ; chemical structure ; contact angle ; cotton fabric ; friction ; hydrophobicity ; oils ; topography ; wettability
Language	English
Dates of publication	2022-0902
Size	p. 1838-1844.
Publishing place	Taylor & Francis
Document type	Article
ISSN	1754-2340
DOI	10.1080/00405000.2021.1952805
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Physiological and transcriptomic responses of antioxidant system and nitrogen metabolism in tomato seedlings treated with nitrogen starvation and re-supply

Dong, Yanyan / Zhai, Jiali / Yan, Jinping / Li, Kunzhi / Xu, Huini

The Journal of Horticultural Science and Biotechnology. 2023 Jan. 02, v. 98, no. 1 p.57-71

2023

Abstract: Nitrogen (N) is one of the essential macronutrients that play important roles in plant growth and development. To better understand the response of antioxidant system and Nmetabolism under Nstarvation and re-supply condition, physiological and ... ...

Abstract	Nitrogen (N) is one of the essential macronutrients that play important roles in plant growth and development. To better understand the response of antioxidant system and Nmetabolism under Nstarvation and re-supply condition, physiological and transcriptomic analyses were performed in tomato (Solanum lycopersicum L.). The malondialdehyde (MDA) and reactive oxygen species (ROS) contents increased significantly, while the superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and monodehydroascorbate reductase (MDHAR) activities, the ratio of ASA/DHA and GSH/GSSG, the NO₃ ⁻ contents, nitrate reductase (NR) activities decreased after Nstarvation treatment. Compared with the control, 1766 genes were up-regulated and 2244 genes were down-regulated after Nstarvation. These differentially expressed genes (DEGs) are mainly enriched in functional items such as cellular process, metabolic process and catalytic activity. The KEGG pathways revealed that the DEGs were mainly involved in phenpropane biosynthesis, amino sugar and nucleotide sugar metabolism, and Nmetabolism. The expression of SlSOD, SlCAT, SlAPX, SlMDHAR, SlTrxh, SlPrx, SlGrx, SlNRT2.4, SlNR, SlGS2, and SlNiR decreased after Nstarvation and increased after Nre-supply, which were validated by qRT-PCR. Our results provide abasis for understanding the response of tomato to Ndeficiency and resupply and atheoretical reference for cultivation regulation.
Keywords	Solanum lycopersicum ; ascorbate peroxidase ; biosynthesis ; biotechnology ; catalase ; catalytic activity ; gene expression regulation ; growth and development ; horticulture ; malondialdehyde ; monodehydroascorbate reductase (NADH) ; nitrate reductase ; nitrogen ; nitrogen metabolism ; plant growth ; reactive oxygen species ; starvation ; sugars ; superoxide dismutase ; tomatoes ; transcriptomics ; Nitrogen starve ; tomato ; transcriptome ; N metabolism
Language	English
Dates of publication	2023-0102
Size	p. 57-71.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	1416403-6
ISSN	2380-4084 ; 1462-0316
ISSN (online)	2380-4084
ISSN	1462-0316
DOI	10.1080/14620316.2022.2079566
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: [Retrospective Study of Bronchoscopic Intervention Therapy for Bronchopleural Fistula Induced by Pulmonary Surgery].

Huo, Xiaosen / Li, Yuan / Dong, Yanyan / Bian, Lingjie / An, Peng / Zou, Hang / Li, Lei / Wang, Hongwu

Zhongguo fei ai za zhi = Chinese journal of lung cancer

2024 Volume 27, Issue 3, Page(s) 187–192

Abstract: Background: As a new technique developed in recent years, bronchoscopic intervention therapy has the advantages of minimal invasion, high safety and repeatability. The aim of this study is to investigate the clinical characteristics of bronchopleural ... ...

Abstract	Background: As a new technique developed in recent years, bronchoscopic intervention therapy has the advantages of minimal invasion, high safety and repeatability. The aim of this study is to investigate the clinical characteristics of bronchopleural fistula (BPF) induced by surgeries for lung malignancies or benign diseases and the effect of bronchoscopic intervention therapy for BPF, so as to provide support for prevention and treatment of BPF. Methods: Data 64 patients with BPF who were treated by bronchoscopic intervention in Respiratory Disease Center of Dongzhimen Hospital, Beijing University of Chinese Medicine from June 2020 to September 2023 were collected. Patients with fistula diameter ≤5 mm were underwent submucous injection of macrogol, combined with blocking therapy with N-butyl cyanoacrylate, medical bioprotein glue or silicone prosthesis. Patients with fistula diameter >5 mm were implanted with different stents and cardiac occluders. Locations and characteristics of fistulas were summarized, meanwhile, data including Karnofsky performance status (KPS), shortbreath scale (SS), body temperature, pleural drainage volume and white blood cell count before and after operation were observed. Results: For all 64 patients, 96 anatomic lung resections including pneumonectomy, lobectomy and segmentectomy were executed and 74 fistulas occurred in 65 fistula locations. The proportion of fistula in the right lung (63.5%) was significantly higher than that in the left (36.5%). Besides, the right inferior lobar bronchial fistula was the most common (40.5%). After operation, KPS was significantly increased, while SS, body temperature, pleural drainage volume and white blood cell count were significantly decreased compared to the preoperative values (P<0.05). By telephone follow-up or readmission during 1 month to 38 months after treament, median survival time was 21 months. 33 patients (51.6%) showed complete response, 7 patients (10.9%) showed complete clinical response, 18 patients (28.1%) showed partial response, and 6 patients (9.4%) showed no response. As a whole, the total effective rate of bronchoscopic intervention for BPF was 90.6%. Conclusions: BPF induced by pulmonary surgery can lead to severe symptoms and it is usually life-threating. Bronchoscopic intervention therapy is one of the fast and effective therapeutic methods for BPF.
MeSH term(s)	Humans ; Bronchial Fistula/etiology ; Bronchial Fistula/surgery ; Retrospective Studies ; Lung Neoplasms/surgery ; Lung Neoplasms/etiology ; Pleural Diseases/etiology ; Pleural Diseases/surgery ; Pleura ; Pneumonectomy/adverse effects
Language	Chinese
Publishing date	2024-04-08
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2438672-8
ISSN	1999-6187 ; 1009-3419
ISSN (online)	1999-6187
ISSN	1009-3419
DOI	10.3779/j.issn.1009-3419.2024.106.03
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Article ; Online: C-Reactive Protein-to-Albumin Ratio Predicts Sepsis and Prognosis in Patients with Severe Burn Injury.

Yu, Yaohua / Wu, Weiwei / Dong, Yanyan / Li, Jiliang

Mediators of inflammation

2021 Volume 2021, Page(s) 6621101

Abstract: Background: Sepsis is a leading cause of mortality among severe burns. This study was conducted to investigate the predictive role of C-reactive protein-to-albumin ratio (CAR) for sepsis and prognosis in severe burns.: Methods: Patients with severe ... ...

Abstract	Background: Sepsis is a leading cause of mortality among severe burns. This study was conducted to investigate the predictive role of C-reactive protein-to-albumin ratio (CAR) for sepsis and prognosis in severe burns. Methods: Patients with severe burn injuries from 2013 to 2017 were enrolled and divided into septic and nonseptic groups based on the presence of sepsis within 30 days postburn. Independent risk factors for sepsis were performed by the univariate and multivariate logistic regression analyses. The association between CAR level at admission and postburn 30-day mortality was designed via the Kaplan-Meier method. Results: Of all the 196 enrolled patients, 83 patients developed sepsis within 30 days postburn injury, with an incidence of 42.3%. TBSA percentage (OR: 1.65, 95% CI: 1.17-2.32, Conclusions: The CAR level at admission was an independent risk factor for sepsis and prognosis in severe burns.
MeSH term(s)	Adult ; Burns/complications ; Burns/mortality ; C-Reactive Protein/analysis ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Factors ; Sepsis/blood ; Sepsis/etiology ; Serum Albumin/analysis
Chemical Substances	Serum Albumin ; C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2021-03-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	1137605-3
ISSN	1466-1861 ; 0962-9351
ISSN (online)	1466-1861
ISSN	0962-9351
DOI	10.1155/2021/6621101
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Article ; Online: Co-delivery of siBcl-2 and PTX with mitochondria-targeted functions to overcoming multidrug resistance.

Zhang, Liqiao / Cao, Xinyu / Chen, Jiayi / Dong, Yanyan / Chen, Wenwen / Gao, Yu / Guo, Jingjing / Huang, Haiqin

International journal of pharmaceutics

2024 Volume 654, Page(s) 123970

Abstract: Multidrug resistance (MDR) poses a significant impediment to the efficacy of chemotherapy in clinical settings. Despite Paclitaxel (PTX) being designated as the primary pharmaceutical agent for treating recurrent and metastatic breast cancer, the ... ...

Abstract	Multidrug resistance (MDR) poses a significant impediment to the efficacy of chemotherapy in clinical settings. Despite Paclitaxel (PTX) being designated as the primary pharmaceutical agent for treating recurrent and metastatic breast cancer, the emergence of PTX resistance frequently results in therapeutic shortcomings, representing a substantial obstacle in clinical breast cancer management. In response, we developed a delivery system exhibiting dual specificity for both tumors and mitochondria. This system facilitated the sequential administration of small interfering B-cell lymphoma-2 (siBcl-2) and PTX to the tumor cytoplasm and mitochondria, respectively, with the aim of surmounting PTX resistance in tumor cells through the activation of the mitochondrial apoptosis pathway. Notably, we employed genetic engineering techniques to fabricate a recombinant ferritin containing the H-subunit (HFn), known for its tumor-targeting capabilities, for loading siBcl-2. This HFn-siBcl-2 complex was then combined with positively charged Triphenylphosphine-Liposome@PTX (TL@PTX) nanoparticles (NPs) to formulate HFn/siBcl-2@TL/PTX. Guided by HFn, these nanoparticles efficiently entered cells and released siBcl-2 through the action of triphenylphosphine (TPP)-mediated "proton sponge," thereby precisely modulating the expression of Bcl-2 protein. Simultaneously, PTX was directed to the mitochondria through the accurate targeting of TL@PTX, synergistically initiating the mitochondrial apoptosis pathway and effectively suppressing PTX resistance both in vitro and in vivo. In conclusion, the development of this dual-targeting delivery system presents a promising therapeutic strategy for overcoming PTX resistance in the clinical treatment of breast cancer.
MeSH term(s)	Humans ; Female ; Paclitaxel ; Drug Resistance, Neoplasm ; Mitochondria ; Breast Neoplasms/pathology ; Drug Resistance, Multiple ; Nanoparticles ; Cell Line, Tumor ; Drug Delivery Systems/methods ; Organophosphorus Compounds
Chemical Substances	Paclitaxel (P88XT4IS4D) ; triphenylphosphine (26D26OA393) ; Organophosphorus Compounds
Language	English
Publishing date	2024-03-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	428962-6
ISSN	1873-3476 ; 0378-5173
ISSN (online)	1873-3476
ISSN	0378-5173
DOI	10.1016/j.ijpharm.2024.123970
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Zs.A 1409: Show issues

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Article ; Online: The effect of sitting baduanjin in patients with ST-segment elevation acute myocardial infarction after percutaneous coronary intervention: A quasi-experimental study.

Cao, Xiaocui / Dong, Yanyan / Yu, Hongjing / Liu, Xuemei / Gu, Yuqin / Song, Jian / Ouyang, Peng / Hong, Zehang

Heart & lung : the journal of critical care

2024 Volume 66, Page(s) 78–85

Abstract: Background: Early cardiac rehabilitation plays a crucial role in the recovery of patients with ST-segment elevation acute myocardial infarction (STEMI) following percutaneous coronary intervention (PCI). This study sought to determine the effect of a ... ...

Abstract	Background: Early cardiac rehabilitation plays a crucial role in the recovery of patients with ST-segment elevation acute myocardial infarction (STEMI) following percutaneous coronary intervention (PCI). This study sought to determine the effect of a program of sitting Baduanjin exercises on early cardiac rehabilitation. Objective: The goal of this study was to investigate the effects of sitting Baduanjin exercises on cardiovascular and psychosocial functions in patients with STEMI following PCI. Methods: This quasi-experimental study employed a randomized, non-equivalent group design. Patients in the intervention group received daily sitting Baduanjin training in addition to a series of seven-step rehabilitation exercises, whereas those in the control group received only the seven-step rehabilitation training, twice daily. Differences in heart rate variability (HRV) indicators, exercise capacity (Six-Minute Walking Distance; 6-MWD), anxiety (Generalized Anxiety Disorder-7; GAD-7), and depression (Patient Health Questionnaire-9; PHQ-9) between the two study groups during hospitalization were analyzed. Results: Patients in the intervention group exhibited lower rates of abnormalities in the time domain and frequency domain parameters of HRV. The median scores of GAD-7 and PHQ-9 in both groups were lower than those at the time of admission, with the intervention group exhibiting lower scores than the control group (P < 0.001; P < 0.001, respectively). The 6-MWD after the intervention was greater in the intervention group compared to the control group (P = 0.014). Conclusions: We found that sitting Baduanjin training has the potential to enhance HRV, cardiac function, and psychological well-being in patients with STEMI after PCI. This intervention can potentially improve the exercise capacity of a patient before discharge.
Language	English
Publishing date	2024-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	193129-5
ISSN	1527-3288 ; 0147-9563
ISSN (online)	1527-3288
ISSN	0147-9563
DOI	10.1016/j.hrtlng.2024.04.003
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Zs.A 1035: Show issues

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Article ; Online: Effective myocardial infarction treatment by targeted accumulation of Sulforaphane using porous magnetic silica nanoparticles.

Zhang, Jian / Dong, Yanyan / Liu, Xue / Jin, Hongbo / Wang, Shuyuan / An, Na / Wang, Lei

International journal of pharmaceutics

2023 Volume 645, Page(s) 123389

Abstract: Myocardial infarction (MI) is a common cardiovascular pathology that induces extensive sterile inflammation during its early stages, posing a severe threat to human health. Effectively modulating cardiac inflammation may improve post-MI outcomes. ... ...

Abstract	Myocardial infarction (MI) is a common cardiovascular pathology that induces extensive sterile inflammation during its early stages, posing a severe threat to human health. Effectively modulating cardiac inflammation may improve post-MI outcomes. Unfortunately, owing to the side effects of therapeutic drugs and cardiac coronary artery occlusion, current MI drugs are sub-optimal for the clinical management of ischemic myocardia. Sulforaphane (SFN) has been adopted for MI treatment due to its myocardial protective effects and low toxicity. However, the targeted accumulation of SFN in infarcted areas remains challenging. Herein, porous magnetic silica nanoparticles (PMSNs) were synthesized and loaded with SFN to improve the specificity of targeted SFN delivery to infarcted areas in mouse models of MI. PMSNs loaded with SFN (PMSNs + SFN) decreased the levels of pro-inflammatory cytokines, thus leading to the improvement of cardiac function and cell survival without adverse effects. To further explore SFN's mechanisms of action in MI, a cellular (in vitro) model was established via oxygen and glucose deprivation (OGD). HSF1 and Nrf2 knockdown resulted in a decrease of SFN-induced HSP70 expression in OGD cells. Moreover, as a result of HSP70 knockdown, the pro-survival and anti-inflammatory effects of SFN were blocked in OGD cells. The level of pro-inflammatory cytokines decreased upon HSP70 overexpression, and cell survival rate increased under OGD conditions. In summary, the results confirm that PMSNs are capable of transporting SFN to infarcted areas in the myocardium, where the drug exerts cardioprotective effects against myocardial injury by up-regulating HSP70 through Nrf2/HSF1.
Language	English
Publishing date	2023-09-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	428962-6
ISSN	1873-3476 ; 0378-5173
ISSN (online)	1873-3476
ISSN	0378-5173
DOI	10.1016/j.ijpharm.2023.123389
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