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  1. Article ; Online: SARS-CoV-2 in the first trimester of pregnancy: potential interference in placentation.

    da Silva, João Victor Farias / Silva, Katheryne Suellen Cavalcante / Dos Santos Junior, Valdeci Elias

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2020  Volume 35, Issue 15, Page(s) 3004

    MeSH term(s) COVID-19 ; Female ; Humans ; Placenta ; Placentation ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Trimester, First ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-14
    Publishing country England
    Document type Letter
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2020.1792879
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  2. Article ; Online: Enamel Defects in Deciduous Dentition and Their Association with the Occurrence of Adverse Effects from Pregnancy to Early Childhood.

    Neto, Mário Batista Ciríaco / Silva-Souza, Kassia Paloma da / Maranhão, Valéria Fernandes / Botelho, Kátia Virginia Guerra / Heimer, Mônica Vilela / Dos Santos-Junior, Valdeci Elias

    Oral health & preventive dentistry

    2020  Volume 18, Page(s) 741–746

    Abstract: Purpose: To verify the prevalence of developmental defects of enamel (DDE) in deciduous teeth and analyse the association with adverse events that occurred during pregnancy and early childhood.: Materials and methods: In a cross-sectional study, 152 ... ...

    Abstract Purpose: To verify the prevalence of developmental defects of enamel (DDE) in deciduous teeth and analyse the association with adverse events that occurred during pregnancy and early childhood.
    Materials and methods: In a cross-sectional study, 152 children with an average age of 3.57 ± 1.25 years were examined according to the criteria established by the DDE index. A previously validated questionnaire was given to mothers in order to obtain information regarding: calcium and vitamin D deficiency (measured in mothers); gestational diabetes; gestational undernutrition; weight at birth; neonatal hypoxia; and presence of asthma in early childhood. The clinical exam was conducted by a single examiner calibrated for visual exams (Kappa = 0.84), outdoors on patios of schools with children and examiner knee to knee. Pearson's chi-squared test and Fisher's Exact Test (p < 0.05) were used to determine statistically significant associations between the variables in study. The data were then analysed using a binary logistic regression regression.
    Results: 26.3% of children exhibited DDE. It was possible to verify a statistically significant association between DDE and vitamin D deficiency (p < 0.01), calcium deficiency (p = 0.01), neonatal hypoxia (p = 0.026), and gestational diabetes (p = 0.04). The regression model allowed the conclusion that children who had neonatal hypoxia during childbirth, gestational diabetes or vitamin D deficiency during their gestation were 3.54, 12.47 and 6.40 more likely to exhibit signs of DDE, respectively.
    Conclusion: The prevalence of DDE was considered high and was associated with vitamin D and calcium deficiency during pregnancy, gestational diabetes, and neonatal hypoxia.
    MeSH term(s) Child ; Child, Preschool ; Cross-Sectional Studies ; Dental Enamel ; Dental Enamel Hypoplasia ; Female ; Humans ; Mothers ; Pregnancy ; Prevalence ; Tooth, Deciduous
    Language English
    Publishing date 2020-09-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2136786-3
    ISSN 1757-9996 ; 1602-1622
    ISSN (online) 1757-9996
    ISSN 1602-1622
    DOI 10.3290/j.ohpd.a45077
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  3. Article: SARS-CoV-2 in the first trimester of pregnancy: potential interference in placentation

    da Silva, João Victor Farias / Silva, Katheryne Suellen Cavalcante / Dos Santos Junior, Valdeci Elias

    J Matern Fetal Neonatal Med

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #646271
    Database COVID19

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  4. Article ; Online: SARS-CoV-2 in the first trimester of pregnancy

    da Silva, João Victor Farias / Silva, Katheryne Suellen Cavalcante / dos Santos Junior, Valdeci Elias

    The Journal of Maternal-Fetal & Neonatal Medicine

    potential interference in placentation

    2020  , Page(s) 1–1

    Keywords Obstetrics and Gynaecology ; Pediatrics, Perinatology, and Child Health ; covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ISSN 1476-7058
    DOI 10.1080/14767058.2020.1792879
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Evaluation of the genotoxic effects of formocresol application in vital pulp therapy of primary teeth: a clinical study and meta-analysis.

    de Alencar Filho, Arnoldo Vasconcelos / Dos Santos Junior, Valdeci Elias / da Silva Calixto, Merilane / Santos, Neide / Heimer, Monica Vilela / Rosenblatt, Aronita

    Clinical oral investigations

    2018  Volume 22, Issue 7, Page(s) 2553–2558

    Abstract: Objectives: This in vivo research investigated whether pulp treatments using formocresol for 7 days would cause mutagenic changes in children's lymphocytes.: Materials and methods: The mutagenicity was tested in lymphocyte cultures established from ... ...

    Abstract Objectives: This in vivo research investigated whether pulp treatments using formocresol for 7 days would cause mutagenic changes in children's lymphocytes.
    Materials and methods: The mutagenicity was tested in lymphocyte cultures established from the peripheral blood of children living in Brazil. The samples consisted of 2000 cells from teeth undergoing formocresol pulpotomies in which the formocresol pellet was sealed in the primary tooth for 7 days. It was removed on the seventh day, the base was placed, and the tooth was restored. Two venous blood samples (6-8 ml) were collected from each child; the first was prior to pulp therapy, and the second was 7 days later. Two thousand metaphases were analyzed. The level of significance adopted for the statistics was P < 0.05, and a random effects meta-analysis was performed combining this and two previous studies.
    Results: There was no significant difference found in the metaphase analysis between the blood samples taken before and after the pulpotomy treatment (Wilcoxon signed rank test); however, the meta-analysis showed a significant difference between the combined studies.
    Conclusions: This study did not reveal any mutagenic effects, but based on the combined meta-analysis, we recommend the careful use of formocresol.
    Clinical relevance: This research helps to bring scientific evidence of the safe use of formocresol in deciduous pulpotomy treatments.
    MeSH term(s) Brazil ; Cells, Cultured ; Child ; Child, Preschool ; Dental Pulp/drug effects ; Female ; Formocresols/toxicity ; Humans ; Lymphocytes/drug effects ; Male ; Mutagenicity Tests ; Pulpotomy ; Tooth, Deciduous
    Chemical Substances Formocresols ; formocresol (37203-87-5)
    Language English
    Publishing date 2018-02-06
    Publishing country Germany
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-018-2352-y
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    Zs.A 4788: Show issues Location:
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  6. Article ; Online: Early childhood caries and its relationship with perinatal, socioeconomic and nutritional risks: a cross-sectional study.

    dos Santos Junior, Valdeci Elias / de Sousa, Rebeca Maria Brasileiro / Oliveira, Maria Cecília / de Caldas Junior, Arnaldo França / Rosenblatt, Aronita

    BMC oral health

    2014  Volume 14, Page(s) 47

    Abstract: Background: Socioeconomic, perinatal and other life cycle events can be important determinants of the health status of the individual and populations. This study aimed to assess the prevalence of early childhood caries (ECC), perinatal factors ( ... ...

    Abstract Background: Socioeconomic, perinatal and other life cycle events can be important determinants of the health status of the individual and populations. This study aimed to assess the prevalence of early childhood caries (ECC), perinatal factors (gestational age, teenage pregnancy and birth weight), family income and nutritional risk in children.
    Methods: A cross-sectional study in which 320 children were examined according to the criteria established by the World Health Organization. A previously validated questionnaire was used to obtain information from parents and guardians about family income, gestational age and birth weight. To check the nutritional risk, we used the criteria provided by the CDC (Center for Disease Control). For Statistics, Pearson's, chi-square and the multivariate Poisson analyses were used to determine the association among variables.
    Results: Approximately 20% of children had ECC, and the Poisson multivariate analyses indicated that family income (p = 0.009), birth weight (p < 0.001) and infant obesity (p < 0.001) were related to the increase of ECC, and gestational age was not significantly associated with ECC (p = 0.149). Pregnancy in adolescence was not included in the regression analyses model because it was not statistically significant in the chi-square test (p > 0.05).
    Conclusion: The prevalence of ECC was related to low family income, premature birth and infant obesity.
    MeSH term(s) Adolescent ; Birth Weight ; Body Mass Index ; Body Weight ; Brazil/epidemiology ; Child, Preschool ; Cross-Sectional Studies ; Dental Caries/epidemiology ; Epidemiologic Studies ; Female ; Gestational Age ; Humans ; Income/statistics & numerical data ; Nutritional Status ; Obesity/epidemiology ; Pregnancy ; Pregnancy in Adolescence/statistics & numerical data ; Premature Birth/epidemiology ; Prevalence ; Risk Factors ; Social Class
    Language English
    Publishing date 2014-05-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2091511-1
    ISSN 1472-6831 ; 1472-6831
    ISSN (online) 1472-6831
    ISSN 1472-6831
    DOI 10.1186/1472-6831-14-47
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  7. Article: Effects of a New Nano-Silver Fluoride-Containing Dentifrice on Demineralization of Enamel and

    Teixeira, Joás Araújo / Silva, Amitis Vieira Costa E / Dos Santos Júnior, Valdeci Elias / de Melo Júnior, Paulo Correia / Arnaud, Manuela / Lima, Maria Goretti / Flores, Miguel Angel Pelagio / Stamford, Thayza Christina Montenegro / Dias Pereira, José Ricardo / Ribeiro Targino, Andréa Gadelha / Galembeck, André / Rosenblatt, Aronita

    International journal of dentistry

    2018  Volume 2018, Page(s) 1351925

    Abstract: An experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were ... ...

    Abstract An experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were tested
    Language English
    Publishing date 2018-05-08
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2546524-7
    ISSN 1687-8736 ; 1687-8728
    ISSN (online) 1687-8736
    ISSN 1687-8728
    DOI 10.1155/2018/1351925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An innovative approach to treating dental decay in children. A new anti-caries agent.

    Targino, Andréa Gadelha Ribeiro / Flores, Miguel Angel Pelagio / dos Santos Junior, Valdeci Elias / de Godoy Bené Bezerra, Fabiana / de Luna Freire, Hilzeth / Galembeck, André / Rosenblatt, Aronita

    Journal of materials science. Materials in medicine

    2014  Volume 25, Issue 8, Page(s) 2041–2047

    Abstract: The aim of this work is to evaluate the antimicrobial and cytotoxic activity of a formulation containing silver nanoparticles and chitosan, provisionally called nano silver fluoride (NSF), against Streptococcus mutans in comparison to chlorhexidine and ... ...

    Abstract The aim of this work is to evaluate the antimicrobial and cytotoxic activity of a formulation containing silver nanoparticles and chitosan, provisionally called nano silver fluoride (NSF), against Streptococcus mutans in comparison to chlorhexidine and silver diamine fluoride (SDF). The product was characterised by transmission electron microscopy and UV-Vis absorption spectroscopy. The minimum inhibition concentration (MIC) was evaluated by the spectrophotometric microdilution method and turbidity. The minimum bactericide concentration (MBC) was evaluated in brain heart infusion plates, and cytotoxicity was evaluated by haemolytic activity. The MIC and MBC for NSF were, respectively, 33.54 ± 14.52 and 50.32 µg/mL; for SDF were 33.33 ± 14.43 and 50.0 µg/mL, respectively; and for CHX were 3.3 ± 0.5 and 6 µg/mL, respectively. An ANOVA for MIC gave P = 0.032, and for MBC P = 0.035. The cytotoxic effect of NSF compared to SDF demonstrated a statistically significant difference in the MIC value (t test P < 0.05). The NSF formulation may be effective against S. mutans with much lower doses, may have lower toxicity than SDF, and may not stain teeth.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Child ; Dental Caries/drug therapy ; Humans ; Metal Nanoparticles ; Microbial Sensitivity Tests ; Microscopy, Electron, Transmission ; Spectrophotometry, Ultraviolet ; Streptococcus mutans/drug effects
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2014-05-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1031752-1
    ISSN 1573-4838 ; 0957-4530
    ISSN (online) 1573-4838
    ISSN 0957-4530
    DOI 10.1007/s10856-014-5221-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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