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  1. Article: Postoperative pancreatic fistula after distal pancreatectomy: pancreatic thickness and duct size as the only denominators?

    Notte, Antoine / Doussot, Alexandre

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 2, Page(s) 229–231

    Language English
    Publishing date 2023-03-15
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-47
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antesitum extended right hepatectomy with vena cava replacement for alveolar ecchinococcosis (with video).

    Doussot, A / Turco, C / Heyd, B

    Journal of visceral surgery

    2020  Volume 157, Issue 6, Page(s) 529–530

    MeSH term(s) Adult ; Albendazole/therapeutic use ; Anthelmintics/therapeutic use ; Budd-Chiari Syndrome/parasitology ; Budd-Chiari Syndrome/surgery ; Echinococcosis, Hepatic/drug therapy ; Echinococcosis, Hepatic/surgery ; Female ; Hepatectomy/methods ; Humans ; Vena Cava, Inferior/surgery
    Chemical Substances Anthelmintics ; Albendazole (F4216019LN)
    Language English
    Publishing date 2020-08-25
    Publishing country France
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ISSN 1878-7886
    ISSN (online) 1878-7886
    DOI 10.1016/j.jviscsurg.2020.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comment on: local control and survival after induction chemotherapy and ablative radiation versus resection for pancreatic ductal adenocarcinoma with vascular involvement.

    Georges, Pauline / Doussot, Alexandre

    Hepatobiliary surgery and nutrition

    2021  Volume 10, Issue 5, Page(s) 672–674

    Language English
    Publishing date 2021-10-21
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-21-336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ex Situ

    Doussot, Alexandra / Bakaï, Marie-France / Fouquet, Eric / Hermange, Philippe

    Organic letters

    2023  Volume 25, Issue 25, Page(s) 4661–4665

    Abstract: Near-stoichiometric amounts ... ...

    Abstract Near-stoichiometric amounts of
    MeSH term(s) Oxygen/chemistry ; Oxidation-Reduction ; Phenols
    Chemical Substances Oxygen (S88TT14065) ; Phenols
    Language English
    Publishing date 2023-06-05
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c01487
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  5. Article ; Online: ASO Author Reflections: Challenges in the Management of Synchronous Prostate Cancer and Rectal Cancer: Towards Double Organ Preservation?

    Doussot, Alexandre / Lakkis, Zaher

    Annals of surgical oncology

    2020  Volume 27, Issue 11, Page(s) 4294–4295

    MeSH term(s) Humans ; Male ; Multicenter Studies as Topic ; Neoplasms, Multiple Primary/therapy ; Organ Sparing Treatments ; Prostatic Neoplasms/therapy ; Rare Diseases ; Rectal Neoplasms/therapy
    Language English
    Publishing date 2020-05-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-08685-2
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    Zs.A 4042: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: We Asked the Experts: How Do We Maintain Surgical Quality Standards for Enhanced Recovery Programs After Cancer Surgery During the COVID-19 Outbreak?

    Doussot, Alexandre / Heyd, Bruno / Lakkis, Zaher

    World journal of surgery

    2020  Volume 44, Issue 7, Page(s) 2051–2052

    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country United States
    Document type Editorial
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-020-05546-7
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    Zs.A 1336: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Robotic-assisted Roux-en-Y cystojejunostomy for pancreatic pseudocyst (with video).

    Doussot, A / Perrin, T / Rat, P / Facy, O

    Journal of visceral surgery

    2016  Volume 153, Issue 5, Page(s) 385–386

    MeSH term(s) Anastomosis, Roux-en-Y/methods ; Drainage/methods ; Humans ; Jejunum/surgery ; Male ; Middle Aged ; Pancreas/surgery ; Pancreatic Pseudocyst/surgery ; Robotic Surgical Procedures/methods
    Keywords covid19
    Language English
    Publishing date 2016
    Publishing country France
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ISSN 1878-7886
    ISSN (online) 1878-7886
    DOI 10.1016/j.jviscsurg.2016.06.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Anatomic patterns of anastomotic leaks after Ivor Lewis esophagectomy for cancer: Impact on management and outcomes.

    Laydi, Maxime / Doussot, Alexandre / Lakkis, Zaher / Mathieu, Pierre / Gandon, Anne / Dubois, Clément / Degisors, Sébastien / Martin, Louis / Heyd, Bruno / Piessen, Guillaume

    Surgery

    2023  Volume 174, Issue 2, Page(s) 247–251

    Abstract: Background: Anastomotic leakage presentation after Ivor Lewis esophagectomy may vary on imaging. Such variations may influence anastomotic leakage management and outcomes.: Methods: All consecutive patients who underwent Ivor Lewis esophagectomy for ... ...

    Abstract Background: Anastomotic leakage presentation after Ivor Lewis esophagectomy may vary on imaging. Such variations may influence anastomotic leakage management and outcomes.
    Methods: All consecutive patients who underwent Ivor Lewis esophagectomy for cancer between 2012 and 2019 in 2 referral centers were included. Anatomical patterns of anastomotic leakage were defined on imaging as follows: eso-mediastinal anastomotic leakage was a leak contained in the posterior mediastinum, eso-pleural anastomotic leakage was a leak involving the pleural cavity, and eso-bronchial anastomotic leakage was a leak communicating with the tracheobronchial tract. According to the Esophageal Complications Consensus Group definition, management and 90-day mortality were evaluated according to these patterns.
    Results: Among 731 patients, 111 (15%) developed anastomotic leakage consisting of eso-mediastinal anastomotic leakage (n = 87, 79%), eso-pleural anastomotic leakage (n = 16, 14%) and eso-bronchial anastomotic leakage (n = 8, 7%). There was no difference among these groups regarding preoperative characteristics or time to anastomotic leakage diagnosis. There was a significant difference in initial management according to anastomotic leakage anatomic patterns (P = .001). More than half of patients who experienced eso-mediastinal anastomotic leakage (n = 46, 53%) were initially treated conservatively without requiring intervention (Esophageal Complications Consensus Group type I), whereas most patients with eso-pleural anastomotic leakage (n = 14, 87.5%) and all with eso-bronchial anastomotic leakage (n = 8, 100%) initially required interventional or surgical treatment (Esophageal Complications Consensus Group type II-III). Anastomotic leakage anatomic patterns had a statistically significant impact on 90-day mortality, intensive care unit stay, and total hospital stay (P < .001).
    Conclusion: Anastomotic leakage anatomic patterns after Ivor Lewis esophagectomy influence outcomes. Further studies are warranted to validate it in a prospective setting. Anastomotic leakage anatomic patterns may help in guiding anastomotic leakage management.
    MeSH term(s) Humans ; Anastomotic Leak/diagnosis ; Anastomotic Leak/epidemiology ; Anastomotic Leak/etiology ; Esophagectomy/adverse effects ; Esophagectomy/methods ; Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/methods ; Prospective Studies ; Esophageal Neoplasms ; Retrospective Studies ; Postoperative Complications/diagnosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2023.04.034
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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.129: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Intra-operative fluorescence angiography is reproducible and reduces the rate of anastomotic leak after colorectal resection for cancer: a prospective case-matched study.

    Wojcik, M / Doussot, A / Manfredelli, S / Duclos, C / Paquette, B / Turco, C / Heyd, B / Lakkis, Z

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2020  Volume 22, Issue 10, Page(s) 1263–1270

    Abstract: Aim: Intra-operative fluorescence angiography (IOFA) with indocyanine green provides information on tissue perfusion that may help prevent an anastomotic leak (AL). The aim of this study was to assess the impact of IOFA on outcomes after left-sided ... ...

    Abstract Aim: Intra-operative fluorescence angiography (IOFA) with indocyanine green provides information on tissue perfusion that may help prevent an anastomotic leak (AL). The aim of this study was to assess the impact of IOFA on outcomes after left-sided colonic or low anterior resection with anastomosis for colorectal cancer.
    Methods: All patients with left-sided colonic or rectal cancer, operated between June 2017 and December 2018, were prospectively included. IOFA has been routinely implemented since May 2018. Reproducibility of IOFA, after a 1:1 matching for relevant clinical risk factors of AL, was studied in patients with IOFA (IOFA+) and without IOFA (IOFA-). Outcomes were compared in terms of postoperative events such as clinically relevant AL as the primary end-point.
    Results: In the IOFA+ group, changing of the initially planned colon transection due to inadequate perfusion occurred in five out of 46 patients (10.9%). Agreement between intra-operative assessment and postoperative blind review of IOFA was deemed strong (Cohen's kappa index 0.893, 95% CI 0.788-0.998, P < 0.001). Among 111 patients, 42 matched patients were included in each group. There was significantly more clinically relevant AL in the IOFA- group compared to the IOFA+ group (16.7% vs 2.4%, P = 0.026) involving significantly more anastomotic dehiscence which required re-intervention (19% vs 2.4%, P = 0.014). Additionally, more descending colon ischaemia/necrosis was observed in the IOFA- group compared with the IOFA+ group (9.5% vs 0%, P = 0.040).
    Conclusion: In this prospective case-matched study, IOFA decreased the occurrence of clinically relevant AL due to necrosis of the descending colon or anastomosis. Upon blind review, perfusion assessment using IOFA was reproducible.
    MeSH term(s) Anastomosis, Surgical/adverse effects ; Anastomotic Leak/etiology ; Anastomotic Leak/prevention & control ; Colon/surgery ; Fluorescein Angiography ; Humans ; Indocyanine Green ; Prospective Studies ; Rectal Neoplasms ; Reproducibility of Results
    Chemical Substances Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2020-05-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.15076
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: MEK inhibitors combined with programmed cell death-1 blockade immunotherapy for metastatic uveal melanoma: is it warranted?

    Zanella, Anais / Doussot, Alexandre / Puzenat, Eve / Aubin, François / Nardin, Charlée

    Melanoma research

    2020  Volume 30, Issue 6, Page(s) 606–607

    Abstract: In the setting of metastatic uveal melanoma (mUM), prognosis is dismal and treatment options are limited. MEK inhibition using selumetinib has led to promising results with improved progression-free survival. While immune checkpoint inhibitors such as ... ...

    Abstract In the setting of metastatic uveal melanoma (mUM), prognosis is dismal and treatment options are limited. MEK inhibition using selumetinib has led to promising results with improved progression-free survival. While immune checkpoint inhibitors such as programmed cell death-1 (PD-1) blockade therapy (anti-PD-1) has shown discrete efficacy in mUM, combining MEK inhibitors (MEKi) to anti-PD-1 might be an option as such combinations have shown synergistic efficacy in metastatic cutaneous melanoma. We report here and discuss our experience in three patients who received this combination in the absence of suitable alternative treatment. The efficacy was difficult to assess due to early severe toxicities (pneumonitis and Takotsubo syndrome). This case series highlights the need to evaluate the safety and efficacy of new treatment options such as MEKi and anti-PD-1 for mUM.
    MeSH term(s) Adult ; Female ; Humans ; Immunotherapy ; Male ; Melanoma ; Middle Aged ; Programmed Cell Death 1 Receptor/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Uveal Neoplasms
    Chemical Substances Programmed Cell Death 1 Receptor ; Protein Kinase Inhibitors
    Language English
    Publishing date 2020-06-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1095779-0
    ISSN 1473-5636 ; 0960-8931
    ISSN (online) 1473-5636
    ISSN 0960-8931
    DOI 10.1097/CMR.0000000000000677
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3378: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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