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  1. Book ; Online: Memristive Ising Circuits

    Dowling, V. J. / Pershin, Y. V.

    2022  

    Abstract: The Ising model is of prime importance in the field of statistical mechanics. Here we show that Ising-type interactions can be realized in periodically-driven circuits of stochastic binary resistors with memory. A key feature of our realization is the ... ...

    Abstract The Ising model is of prime importance in the field of statistical mechanics. Here we show that Ising-type interactions can be realized in periodically-driven circuits of stochastic binary resistors with memory. A key feature of our realization is the simultaneous co-existence of ferromagnetic and antiferromagnetic interactions between two neighboring spins -- an extraordinary property not available in nature. We demonstrate that the statistics of circuit states may perfectly match the ones found in the Ising model with ferromagnetic or antiferromagnetic interactions, and, importantly, the corresponding Ising model parameters can be extracted from the probabilities of circuit states. Using this finding, the Ising Hamiltonian is re-constructed in several model cases, and it is shown that different types of interaction can be realized in circuits of stochastic memristors.
    Keywords Condensed Matter - Mesoscale and Nanoscale Physics ; Condensed Matter - Statistical Mechanics ; Computer Science - Emerging Technologies
    Subject code 612
    Publishing date 2022-10-09
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: Analytic and SPICE modeling of stochastic ReRAM circuits

    Dowling, V. J. / Slipko, V. A. / Pershin, Y. V.

    2022  

    Abstract: The modeling of conventional (deterministic) electronic circuits - ones consisting of transistors, resistors, capacitors, inductors, and other traditional electronic components - is a well-established subject. The cycle-to-cycle variability of emerging ... ...

    Abstract The modeling of conventional (deterministic) electronic circuits - ones consisting of transistors, resistors, capacitors, inductors, and other traditional electronic components - is a well-established subject. The cycle-to-cycle variability of emerging electronic devices, in particular, certain ReRAM cells, has led to the concept of stochastic circuits. Unfortunately, even in relatively simple cases, the direct transient analysis of stochastic circuits is computationally demanding and potentially impractical, if possible at all. An important development in this area has been the application of a master equation that is easily implemented in SPICE. In this conference paper, we briefly review the master equation approach and present an improved implementation of this approach in SPICE. Moreover, we find an attractor state in a periodically driven memristive circuit - a stochastic counterpart of deterministic memristor attractors.

    Comment: to be published the Proceedings of SPIE dedicated to ICMNE-2021
    Keywords Computer Science - Emerging Technologies ; Condensed Matter - Mesoscale and Nanoscale Physics
    Publishing date 2022-01-25
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Efficacy in the use of local anesthesia in patients with surgical intervention for the resolution of anorectal pathologies

    Dowling, Victoria / Cortez, Julio

    Journal of Coloproctology

    2018  Volume 38, Issue 01, Page(s) 37–41

    Abstract: A prospective, comparative, longitudinal study was conducted in the period from April 2016 to January 2017 in order to determine the efficacy of local anesthesia for the surgical resolution of anorectal pathologies in surgically operated patients who ... ...

    Abstract A prospective, comparative, longitudinal study was conducted in the period from April 2016 to January 2017 in order to determine the efficacy of local anesthesia for the surgical resolution of anorectal pathologies in surgically operated patients who attended the General University Hospital “Luis Gomez Lopez. Thus, the population was composed of patients with anorectal pathologies of low complexity, with no previous anorectal surgical history (Hemorrhoids, anal fissure, perianal fistula, hypertrophic anal papilla, perianal condyloma acuminata), which were agreed to be included in this study, without contraindications for use of local anesthesia. A non-probabilistic, intentional sample was made up of 30 patients and the anesthetic protocol was administered following an anesthetic protocol of perianal local anesthesia using anesthetic mixture (70% of 2% lidocaine + 30% of 0.5% bupivacaine) quantifying pain tolerance during the intraoperative period on the first and fifth postoperative days, as well as any adverse effects. The results were expressed in absolute numbers and percentages; a good tolerance to pain was observed with some differences related to the sex of the individuals studied; no complications were observed.
    Keywords Anorectal pathologies ; Local anesthesia ; Surgical intervention ; Patologias anorretais ; Anestesia local ; Intervenção cirúrgica
    Language English
    Publishing date 2018-03-01
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2664477-0
    ISSN 2317-6423 ; 2237-9363 ; 2317-6423
    ISSN (online) 2317-6423
    ISSN 2237-9363 ; 2317-6423
    DOI 10.1016/j.jcol.2017.10.004
    Database Thieme publisher's database

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  4. Book ; Online: Probabilistic Memristive Networks

    Dowling, V. J. / Slipko, V. A. / Pershin, Y. V.

    Application of a Master Equation to Networks of Binary ReRAM cells

    2020  

    Abstract: The possibility of using non-deterministic circuit components has been gaining significant attention in recent years. The modeling and simulation of their circuits require novel approaches, as now the state of a circuit at an arbitrary moment in time ... ...

    Abstract The possibility of using non-deterministic circuit components has been gaining significant attention in recent years. The modeling and simulation of their circuits require novel approaches, as now the state of a circuit at an arbitrary moment in time cannot be precisely predicted. Generally, these circuits should be described in terms of probabilities, the circuit variables should be calculated on average, and correlation functions should be used to explore interrelations among the variables. In this paper, we use, for the first time, a master equation to analyze the networks composed of probabilistic binary memristors. Analytical solutions of the master equation for the case of identical memristors connected in-series and in-parallel are found. Our analytical results are supplemented by results of numerical simulations that extend our findings beyond the case of identical memristors. The approach proposed in this paper facilitates the development of probabilistic/stochastic electronic circuits and advance their real-world applications.
    Keywords Computer Science - Emerging Technologies ; Condensed Matter - Mesoscale and Nanoscale Physics ; Condensed Matter - Materials Science
    Publishing date 2020-03-24
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book ; Online: Modeling networks of probabilistic memristors in SPICE

    Dowling, V. J. / Slipko, V. A. / Pershin, Y. V.

    2020  

    Abstract: Efficient simulation of probabilistic memristors and their networks requires novel modeling approaches. One major departure from the conventional memristor modeling is based on a master equation for the occupation probabilities of network states [arXiv: ... ...

    Abstract Efficient simulation of probabilistic memristors and their networks requires novel modeling approaches. One major departure from the conventional memristor modeling is based on a master equation for the occupation probabilities of network states [arXiv:2003.11011 (2020)]. In the present article, we show how to implement such master equations in SPICE - a general-purpose circuit simulation program. In the case studies, we simulate the dynamics of ac-driven probabilistic binary and multi-state memristors, and dc-driven networks of probabilistic binary and multi-state memristors. Our SPICE results are in perfect agreement with known analytical solutions. Examples of LTspice codes are included.
    Keywords Computer Science - Emerging Technologies ; Condensed Matter - Mesoscale and Nanoscale Physics
    Publishing date 2020-09-10
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: The physiological response and recovery of a common elasmobranch bycatch species: the lesser spotted dogfish (Scyliorhinus canicula) subject to a controlled exposure event

    Murray, Clare / Connors, Rebecca / O'Connor, Ian / Dowling, Vera

    Biology and environment

    2015  Volume 115B, Issue 3, Page(s) 143

    Language English
    Document type Article
    ZDB-ID 1169496-8
    ISSN 0791-7945
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 7946: Show issues

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  7. Article ; Audio / Video: Protein carbonylation and heat shock response in Ruditapes decussatus following p,p'-dichlorodiphenyldichloroethylene (DDE) exposure: A proteomic approach reveals that DDE causes oxidative stress

    Dowling, V / Hoarau, P.C / Romeo, M / O'Halloran, J / Van Pelt, F / O'Brien, N / Sheehan, D

    Aquatic toxicology. 2006 Apr. 20, v. 77, issue 1

    2006  

    Abstract: Protein carbonylation and levels of heat shock proteins (hsp; 60, 70 and 90 kDa) were measured in gill, mantle and digestive gland of Ruditapes decussatus following exposure to p,p'-dichlorodiphenyldichloroethylene (DDE). Heat shock response was measured ...

    Abstract Protein carbonylation and levels of heat shock proteins (hsp; 60, 70 and 90 kDa) were measured in gill, mantle and digestive gland of Ruditapes decussatus following exposure to p,p'-dichlorodiphenyldichloroethylene (DDE). Heat shock response was measured by immunoblotting using antibodies specific to heat shock proteins (hsps). Densitometry analysis of individual bands revealed no difference between control and treated samples except appearance of hsp90 in DDE-treated mantle. Carbonylated protein content was determined following 2,4-dinitrophenylhydrazine derivatization and two-dimensional electrophoresis coupled with western blotting. Immunoblotting with dinitrophenol-specific antibody revealed extensive differences in both extent and number of carbonylated proteins in mantle and digestive gland in response to DDE while gill was unaffected. These results demonstrate for the first time that DDE causes tissue-specific formation of reactive oxygen species in clams.
    Keywords water pollution ; DDE (pesticide) ; oxidative stress ; heat stress ; heat shock proteins ; clams ; indicator species
    Language English
    Dates of publication 2006-0420
    Size p. 11-18.
    Document type Article ; Audio / Video
    ZDB-ID 782699-0
    ISSN 1879-1514 ; 0166-445X
    ISSN (online) 1879-1514
    ISSN 0166-445X
    DOI 10.1016/j.aquatox.2005.10.011
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 3881: Show issues

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  8. Article: Forearm fractures in the head-injured adult.

    Garland, D E / Dowling, V

    Clinical orthopaedics and related research

    1983  , Issue 176, Page(s) 190–196

    Abstract: Forty-seven of 661 head-injured adults sustained 50 forearm fractures. Eight extremities exhibited elbow flexion contractures greater than 55 degrees. Traumatic heterotopic ossification at the elbow developed in ten (20%) extremities: four with Monteggia ...

    Abstract Forty-seven of 661 head-injured adults sustained 50 forearm fractures. Eight extremities exhibited elbow flexion contractures greater than 55 degrees. Traumatic heterotopic ossification at the elbow developed in ten (20%) extremities: four with Monteggia fractures, two with olecranon fractures, and four with no known trauma. Only two of 18 (11%) extremities treated by plaster immobilization achieved good or excellent results, while 17 of 32 (53%) extremities treated by open reduction and internal fixation achieved good or excellent results. Union of fractures of one or both bones occurred at the same rate as for the normal population. There were no nonunions or deep infections, and there was only one delayed union. Calcification occurred in the interosseous membrane in 12 extremities (24%). In nine forearms (18%) a complete synostosis developed. One isolated radial fracture treated by open reduction and internal fixation and one isolated ulnar fracture treated by plaster incurred a synostosis. Seven of 21 (33%) fractures of both bones developed synostosis. Five of 16 (31%) fractures of both bones treated by open reduction and internal fixation developed a synostosis. These observations corroborate reports demonstrating that head injury predisposes to heterotopic ossification in forearm fractures.
    MeSH term(s) Adolescent ; Adult ; Craniocerebral Trauma/complications ; Forearm Injuries/complications ; Forearm Injuries/surgery ; Fractures, Bone/complications ; Fractures, Bone/surgery ; Humans ; Middle Aged ; Synostosis/etiology
    Language English
    Publishing date 1983-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80301-7
    ISSN 1528-1132 ; 0009-921X
    ISSN (online) 1528-1132
    ISSN 0009-921X
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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Two-dimensional electrophoresis analysis of glutathione affinity-selected proteins from the clam Tapes semidecussatus: Evidence for tissue-specific expression of redox proteins.

    Dowling, V / McDonagh, B / Cotter, E M / O'Brien, N / van Pelt, F / O'Halloran, J / Sheehan, D

    Comparative biochemistry and physiology. Part D, Genomics & proteomics

    2006  Volume 1, Issue 3, Page(s) 267–272

    Abstract: Proteins from gill, digestive gland and mantle of the clam Tapes semidecussatus were selected on glutathione (GSH) agarose to simplify proteomic comparison. Analysis by two-dimensional gel electrophoresis (2D SDS PAGE) revealed tissue-specific patterns ... ...

    Abstract Proteins from gill, digestive gland and mantle of the clam Tapes semidecussatus were selected on glutathione (GSH) agarose to simplify proteomic comparison. Analysis by two-dimensional gel electrophoresis (2D SDS PAGE) revealed tissue-specific patterns of protein expression with some spots common to all tissues. Immunoblotting of gill and digestive gland separations identified some spots as glutathione transferases (GSTs). In gill and digestive gland several spots were immunoblotted with Pi class GSTs indicating multiple isoenzymes. Selected spots were excised, digested with trypsin and analyzed by reversed phase C-18 high performance liquid chromatography and tandem mass spectrometry. This confirmed that gill and digestive gland share some GST isoenzymes. Our results suggest that this clam expresses a complex tissue-specific pattern of GSH-binding proteins, which may reflect different redox requirements in each tissue.
    Language English
    Publishing date 2006-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2212119-5
    ISSN 1878-0407 ; 1744-117X
    ISSN (online) 1878-0407
    ISSN 1744-117X
    DOI 10.1016/j.cbd.2006.01.002
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    Zs.A 6254: Show issues Location:
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  10. Article ; Online: Determination of non-HDL cholesterol in diabetic and hypertensive patients.

    Contreras, Freddy / Lares, Mary / Castro, Jorge / Velasco, Manuel / Rojas, Joselyn / Guerra, Xavier / Chacín, Maricarmen / Dowling, Victoria / Bermúdez, Valmore

    American journal of therapeutics

    2010  Volume 17, Issue 3, Page(s) 337–340

    Abstract: Recently, it has been suggested that non-high-density lipoprotein (non-HDL) cholesterol measure is a useful evaluation tool to assess heart disease death risk. The non-HDL cholesterol is defined as the value between total cholesterol and HDL - total ... ...

    Abstract Recently, it has been suggested that non-high-density lipoprotein (non-HDL) cholesterol measure is a useful evaluation tool to assess heart disease death risk. The non-HDL cholesterol is defined as the value between total cholesterol and HDL - total cholesterol, and it involves the different fractions of lipoproteins: low-density lipoprotein, intermediate-density lipoprotein, and very low density lipoprotein, including highly atherogenic lipoproteins as very low density lipoprotein remnants. The purpose of this study was to compare the values of non-HDL cholesterol as a cardiovascular risk marker in a control population, and one diabetic and hypertensive. It was demonstrated that the mean values of non-HDL cholesterol in the diseased groups were higher than the values from the control group, whereas the low-density lipoprotein showed no marked difference in high-risk patients. Non-HDL cholesterol has shown to be a quick and simple way to estimate the risk of developing cardiovascular disease.
    MeSH term(s) Adolescent ; Adult ; Biomarkers/blood ; Cardiovascular Diseases/etiology ; Cholesterol/blood ; Cholesterol, HDL/blood ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Female ; Humans ; Hypertension/blood ; Hypertension/complications ; Male ; Middle Aged ; Risk Factors ; Young Adult
    Chemical Substances Biomarkers ; Cholesterol, HDL ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2010-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1280786-2
    ISSN 1536-3686 ; 1075-2765
    ISSN (online) 1536-3686
    ISSN 1075-2765
    DOI 10.1097/MJT.0b013e3181c1233c
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    Zs.A 4351: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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