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  1. Book ; Conference proceedings: Alkohol im Straßenverkehr - ein vermeidbares Übel?

    Dräger, Christian

    Dokumentation eines Symposiums der Dräger-Stiftung in Zusammenarbeit mit dem Deutschen Verkehrssicherheitsrat (DVR), Bonn, und dem European Transport Safety Council (ETSC), Brüssel = Drinking and driving - an avoidable evil?

    1997  

    Title variant Drinking and driving - an avoidable evil?
    Institution Dräger-Stiftung
    Author's details Christian Dräger ; Petra Pissulla (Hrsg.)
    Keywords Trunkenheit ; Verkehr
    Subject Verkehrswesen
    Language German ; English
    Size XI, 147 S., Diagramme, 24 cm
    Edition 1. Aufl.
    Publisher G. Fischer
    Publishing place Lübeck ; Stuttgart ; Jena ; Ulm
    Publishing country Germany
    Document type Book ; Conference proceedings
    Note Beitr. teilw. dt., teilw. engl. - Literaturangaben ; "Symposium Alkohol im Straßenverkehr - ein vermeidbares Übel, ... am 14. und 15. September 1995 in Bonn" (Vorwort)
    HBZ-ID HT019900821
    ISBN 978-3-437-41016-1 ; 3-437-41016-4
    Database Catalogue ZB MED Medicine, Health

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  2. Conference proceedings: Datenqualitätsanalysen im Rahmen der MII-Projectathons

    Draeger, Christian / Löbe, Matthias

    2023  , Page(s) P25

    Event/congress SMITH Science Day 2022; Aachen; Smart Medical Information Technology for Healthcare; 2022
    Keywords Medizin, Gesundheit
    Publishing date 2023-01-31
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/22smith36
    Database German Medical Science

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  3. Conference proceedings: Data Quality Assessment in the seventh MII-Projectathon

    Draeger, Christian / Löbe, Matthias / Meineke, Frank A.

    2023  , Page(s) Abstr. 316

    Event/congress 68. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS); Heilbronn; Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie; 2023
    Keywords Medizin, Gesundheit ; data quality ; data quality analysis ; Medizininformatik-Initiative
    Publishing date 2023-09-15
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23gmds139
    Database German Medical Science

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  4. Article ; Online: Pitfalls in Analyzing FHIR Data from Different University Hospitals.

    Löbe, Matthias / Draeger, Christian / Strübing, Alexander / Palm, Julia / Meineke, Frank A / Winter, Alfred

    Studies in health technology and informatics

    2023  Volume 307, Page(s) 146–151

    Abstract: The German Medical Informatics Initiative has agreed on a HL7 FHIR-based core data set as the common data model that all 37 university hospitals use for their patient's data. These data are stored locally at the site but are centrally queryable for ... ...

    Abstract The German Medical Informatics Initiative has agreed on a HL7 FHIR-based core data set as the common data model that all 37 university hospitals use for their patient's data. These data are stored locally at the site but are centrally queryable for researchers and accessible upon request. This infrastructure is currently under construction, and its functionality is being tested by so-called Projectathons. In the 6th Projectathon, a clinical hypothesis was formulated, executed in a multicenter scenario, and its results were analyzed. A number of oddities emerged in the analysis of data from different sites. Biometricians, who had previously performed analyses in prospective data collection settings such as clinical trials or cohorts, were not consistently aware of these idiosyncrasies. This field report describes data quality problems that have occurred, although not all are genuine errors. The aim is to point out such circumstances of data generation that may affect statistical analysis.
    MeSH term(s) Humans ; Hospitals, University ; Awareness ; Data Accuracy ; Data Collection ; Medical Informatics
    Language English
    Publishing date 2023-09-12
    Publishing country Netherlands
    Document type Multicenter Study ; Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230706
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Modeling the Application of IHE QRPH Profiles in Data Integration Centers: A Practical Approach with 3LGM2.

    Draeger, Christian / Stäubert, Sebastian / Kuntz, Alessandra / Henke, Christian / Winter, Alfred / Sax, Ulrich / Löbe, Matthias

    Studies in health technology and informatics

    2023  Volume 309, Page(s) 126–130

    Abstract: The Data Integration Centers (DICs), all part of the German Medical Informatics Initiative (MII), prepare routine care data captured in university hospitals to enable its reuse in clinical research. Tackling this challenging task requires them to ... ...

    Abstract The Data Integration Centers (DICs), all part of the German Medical Informatics Initiative (MII), prepare routine care data captured in university hospitals to enable its reuse in clinical research. Tackling this challenging task requires them to maintain multiple data stores, implement the necessary transformation processes, and provide the required terminology services, all while also addressing the use case specific needs researchers might have. An MII wide application of the standardized profiles defined in the IHE QRPH domain might therefore be able to drastically reduce the overhead at any one DIC. The MII DIC reference model built in 3LGM2, a method to describe complex information system architectures, serves as a starting point to evaluate whether such an application is possible. We first extend the IHE modeling capabilities of 3LGM2 to also support the five profiles from the QRPH domain that our experts evaluated as relevant in the MII DIC context. We then expand the DIC reference model by some IHE QRPH actors and transactions, showing that their application could be beneficial in the MII DIC context, provided they surpass their trial status.
    MeSH term(s) Humans ; Systems Integration ; Medical Informatics Applications ; Medical Informatics
    Language English
    Publishing date 2023-08-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Identifying Relevant FHIR Elements for Data Quality Assessment in the German Core Data Set.

    Draeger, Christian / Tute, Erik / Schmidt, Carsten Oliver / Waltemath, Dagmar / Boeker, Martin / Winter, Alfred / Löbe, Matthias

    Studies in health technology and informatics

    2023  Volume 302, Page(s) 272–276

    Abstract: The German Medical Informatics Initiative makes clinical routine data available for biomedical research. In total, 37 university hospitals have set up so-called data integration centers to facilitate this data reuse. A standardized set of HL7 FHIR ... ...

    Abstract The German Medical Informatics Initiative makes clinical routine data available for biomedical research. In total, 37 university hospitals have set up so-called data integration centers to facilitate this data reuse. A standardized set of HL7 FHIR profiles ("MII Core Data Set") defines the common data model across all centers. Regular Projectathons ensure continuous evaluation of the implemented data sharing processes on artificial and real-world clinical use cases. In this context, FHIR continues to rise in popularity for exchanging patient care data. As reusing data from patient care in clinical research requires high trust in the data, data quality assessments are a key point of concern in the data sharing process. To support the setup of data quality assessments within data integration centers, we suggest a process for finding elements of interest from FHIR profiles. We focus on the specific data quality measures defined by Kahn et al.
    MeSH term(s) Humans ; Electronic Health Records ; Data Accuracy ; Medical Informatics ; Biomedical Research ; Hospitals, University
    Language English
    Publishing date 2023-05-19
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI230117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Audio / Video ; Thesis: A genetic, biochemical, and biomechanical study of plant cell wall dynamics in pollen tubes

    Draeger, Christian

    2012  

    Author's details Christian Draeger
    Language English
    Size 1 CD-ROM, 12 cm
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Zürich, 2012
    Database Former special subject collection: coastal and deep sea fishing

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  8. Conference proceedings: A glimpse at representing data quality rules for their collaborative governance in the Medical Informatics Initiative

    Tute, Erik / Draeger, Christian / Gierend, Kerstin / Löbe, Matthias / Palm, Julia / Schmidt, Carsten Oliver

    2022  , Page(s) Abstr. 166

    Event/congress 67. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS), 13. Jahreskongress der Technologie- und Methodenplattform für die vernetzte medizinische Forschung e.V. (TMF); sine loco [digital]; Deutsche Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie; 2022
    Keywords Medizin, Gesundheit ; data quality ; medical informatics
    Publishing date 2022-08-19
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/22gmds018
    Database German Medical Science

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  9. Book ; Online ; Thesis: Mesoskopische Micellen aus amphiphilen Bipyridylkomplexen von Ruthenium(II), Osmium(II) und Palladium(II)

    Draeger, Christian

    2001  

    Abstract: In dieser Arbeit sind amphiphile Ru(II)-Komplexe mit zwei parallelen Oligomethylenketten synthetisiert worden, bei denen zwischen den Ketten ein Abstand von ca. 4A besteht. Es wurden Amphiphile mit Ditetradecyl-, Dihexadecyl-, Dioctadecyl-, Dieicosyl- ... ...

    Author's details vorgelegt von Christian Draeger
    Abstract In dieser Arbeit sind amphiphile Ru(II)-Komplexe mit zwei parallelen Oligomethylenketten synthetisiert worden, bei denen zwischen den Ketten ein Abstand von ca. 4A besteht. Es wurden Amphiphile mit Ditetradecyl-, Dihexadecyl-, Dioctadecyl-, Dieicosyl- und Didocosylketten, sowie Derivate mit Methacryl- und Xanthogenylgruppen hergestellt. Außerdem wurden Osmium- und Palladiumkomplexe synthetisiert. Die komplexierten Bipyridine bzw. Dipyridylmethylenmalonate besaßen ein charakteristisches Absorptionsspektrum mit breiter Charge-Transfer Bande (MLCT-Bande). Im Gegensatz zur Lösung in Chloroform, lumineszierten alle wäßrigen Suspensionen. Die intensive Lumineszenz der Aggregate ist auf den sterischen Streß in der extrem steifen Membran zurückzuführen. Beim Einlagern in fluide Vesikel oder Micellen ging die Emission wieder verloren. Bei der TEM-Unterschung der micellaren Lösungen wurden für alle synthetisierten, zweikettigen Ru(II)-Amphiphile mit Hexafluorophosphatgegenionen mehrschalige, kugelförmige Kolloide ohne inneres Wasservolumen gefunden. Die festen, zwiebelartigen Kugeln, welche vollständig mit interdigitierten Doppelschichten ausgefüllt sind, haben den Charakter fester, sphärischer Micellen und nicht von Vesikeln. Kopfgruppenschichten bestehen aus Doppelschichten von entgegengesetzten Ru-Amphiphilen. Die Alkylketten der gegenüberliegenden, kammartigen Amphiphile bilden interdigitierte Doppelschichten aus. Durch verschiedene wasser- oder membranlösliche, redoxaktive Lumineszenzquencher ließ sich die Emission des Dioctadecylderivates um 30-50 % der ursprünglichen Intensität löschen...
    Keywords Platinmetallkomplexe ; Micellbildung ; Amphiphile Verbindungen ; Chemische Synthese ; Bipyridinderivate ; Dipyridylverbindungen
    Language German
    Size Online-Ressource
    Edition Online-Resource
    Publisher Niedersächsische Staats- und Universitätsbibliothek
    Publishing place Göttingen
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Freie Univ., Diss--Berlin, 2001
    Note Dateiformat:zip, Dateien im PDF-Format
    Database Former special subject collection: coastal and deep sea fishing

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  10. Book ; Conference proceedings: Alkohol im Straßenverkehr - ein vermeidbares Übel?

    Dräger, Christian

    Dokumentation eines Symposiums der Dräger-Stiftung in Zusammenarbeit mit dem Deutschen Verkehrssicherheitsrat (DVR), Bonn, und dem European Transport Safety Council (ETSC), Brüssel = Drinking and driving - an avoidable evil?

    1997  

    Title variant Drinking and driving - an avoidable evil?
    Institution Dräger-Stiftung
    Symposium Alkohol im Strassenverkehr - ein Vermeidbares Übel?
    Event/congress Symposium Alkohol im Straßenverkehr - ein vermeidbares Übel (1995.09.14-15, Bonn) ; Symposium Drinking and Driving - an Avoidable Evil? (1995.09.14-15, Bonn)
    Author's details Christian Dräger ... (Hrsg.)
    Keywords Trunkenheit im Verkehr
    Language German ; English
    Size XI, 147 S, graph. Darst, 24 cm
    Edition 1. Aufl
    Publisher Fischer
    Publishing place Lübeck u.a.
    Document type Book ; Conference proceedings
    Note Beitr. teilw. dt., teilw. engl. - Literaturangaben
    ISBN 3437410164 ; 9783437410161
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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