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Article ; Online: Zinc-loaded mesoporous silica nanoparticles mitigate salinity stress in wheat seedlings through silica-zinc uptake, osmotic balance, and ROS detoxification.

Ghosh, Dibakar / Das, Tapas / Paul, Paramita / Dua, Tarun Kumar / Roy, Swarnendu

2024 Volume 211, Page(s) 108693

Abstract: Abiotic stresses like salinity and micronutrient deficiency majorly affect wheat productivity. Applying mesoporous silica nanoparticles (MSiNPs) as a smart micronutrient delivery system can facilitate better stress management and nutrient delivery. In ... ...

Abstract	Abiotic stresses like salinity and micronutrient deficiency majorly affect wheat productivity. Applying mesoporous silica nanoparticles (MSiNPs) as a smart micronutrient delivery system can facilitate better stress management and nutrient delivery. In this purview, we investigated the potential of MSiNPs and Zn-loaded MSiNPs (Zn-MSiNPs) on the growth and physiology of wheat seedlings exposed to salinity stress (200 mM NaCl). Initially, the FESEM, DLS, and BET analysis portrayed nanoparticles' spherical shape, nano-size, and negatively charged mesoporous surface. A sustained release of Zn
Language	English
Publishing date	2024-05-01
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2024.108693
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Article ; Online: Protective effect of probiotics against acetaminophen induced nephrotoxicity.

Dua, Tarun Kumar / Palai, Sangita / Roy, Abani / Paul, Paramita

Molecular biology reports

2022 Volume 49, Issue 8, Page(s) 8139–8143

Abstract: Acetaminophen (APAP) is commonly prescribed as an antipyretic and analgesic agent in the practical field. Like every other drug(s), APAP also undergo metabolism by oxidation or conjugation by glucuronate and sulphate to form the toxic metabolite N-acetyl- ...

Abstract	Acetaminophen (APAP) is commonly prescribed as an antipyretic and analgesic agent in the practical field. Like every other drug(s), APAP also undergo metabolism by oxidation or conjugation by glucuronate and sulphate to form the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI). Moreover, the NAPQI is detoxified by conjugation with reduced glutathione (GSH). Interestingly, APAP is also metabolized in the kidney by deacetylation reaction in the presence of N-deacetylase enzyme into another severely toxic but minor metabolite, p-aminophenol. Both NAPQI and p-aminophenol shows nephrotoxicity as well as hepatotoxicity. Hence, the long-term therapeutic dose use and unnecessary overdose of APAP are of great concern as prolonged negligence may cost the nephrotoxicity that may lead to uremia and finally to kidney failure. It has recently been investigated that probiotic supplementation inhibits the sequential events associated with APAP-induced nephrotoxicity. This review emphasizes the role of different probiotics that have already been investigated in nephrotoxicity or uremia caused by APAP overdose.
MeSH term(s)	Acetaminophen/adverse effects ; Glutathione/metabolism ; Humans ; Probiotics/therapeutic use ; Renal Insufficiency ; Uremia/metabolism
Chemical Substances	Acetaminophen (362O9ITL9D) ; Glutathione (GAN16C9B8O)
Language	English
Publishing date	2022-06-05
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	186544-4
ISSN	1573-4978 ; 0301-4851
ISSN (online)	1573-4978
ISSN	0301-4851
DOI	10.1007/s11033-022-07534-7
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Article ; Online: Impact of ultrasound-assisted extraction of polyphenols and caffeine from green tea leaves using high-performance thin-layer chromatography.

Ashraf, Gouhar Jahan / Das, Priya / Sahu, Ranabir / Nandi, Gouranga / Paul, Paramita / Dua, Tarun Kumar

Biomedical chromatography : BMC

2023 Volume 37, Issue 10, Page(s) e5698

Abstract: Tea is the most popular daily drink consumed globally, with a high concentration of caffeine and polyphenols. In this study, the effects of ultrasonic-assisted extraction and quantification of caffeine and polyphenols from green tea were investigated and ...

Abstract	Tea is the most popular daily drink consumed globally, with a high concentration of caffeine and polyphenols. In this study, the effects of ultrasonic-assisted extraction and quantification of caffeine and polyphenols from green tea were investigated and optimized using 2
MeSH term(s)	Caffeine/analysis ; Polyphenols/analysis ; Chromatography, Thin Layer ; Tea/chemistry ; Plant Extracts/chemistry ; Solvents/chemistry ; Plant Leaves/chemistry ; Chromatography, High Pressure Liquid
Chemical Substances	Caffeine (3G6A5W338E) ; Polyphenols ; Tea ; Plant Extracts ; Solvents
Language	English
Publishing date	2023-07-04
Publishing country	England
Document type	Journal Article
ZDB-ID	632848-9
ISSN	1099-0801 ; 0269-3879
ISSN (online)	1099-0801
ISSN	0269-3879
DOI	10.1002/bmc.5698
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Article: Green synthesis of silver nanoparticles using

Dua, Tarun Kumar / Giri, Simran / Nandi, Gouranga / Sahu, Ranabir / Shaw, Tapan Kumar / Paul, Paramita

Chemicke zvesti

2023 Volume 77, Issue 6, Page(s) 2947–2956

Abstract: The green synthesis of metallic nanoparticles has tremendous impacts in various fields as found in recent years due to their low cost, easy and environmentally friendly synthesis. In this article, we report a simple and eco-friendly method for the ... ...

Abstract	The green synthesis of metallic nanoparticles has tremendous impacts in various fields as found in recent years due to their low cost, easy and environmentally friendly synthesis. In this article, we report a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using an aqueous
Language	English
Publishing date	2023-01-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2252770-9
ISSN	1336-9075 ; 0366-6352
ISSN (online)	1336-9075
ISSN	0366-6352
DOI	10.1007/s11696-023-02676-9
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Article ; Online: Enhanced adaptation to salinity stress in lentil seedlings through the use of trehalose-functionalized silica nanoparticles (TSiNPs): Exploring silica-sugar absorption and oxidative balance.

Sarkar, Mahima Misti / Rudra, Pritha / Paul, Paramita / Dua, Tarun Kumar / Roy, Swarnendu

Plant physiology and biochemistry : PPB

2023 Volume 206, Page(s) 108309

Abstract: Silica nanoparticles (SiNPs) confer better growth and development of plants under salinity stress. Moreover, the surface-functionalization of SiNPs with bioactive molecules is expected to enhance its efficacy. The present study thus aimed to modify the ... ...

Abstract	Silica nanoparticles (SiNPs) confer better growth and development of plants under salinity stress. Moreover, the surface-functionalization of SiNPs with bioactive molecules is expected to enhance its efficacy. The present study thus aimed to modify the surface of SiNPs, by attaching a bioactive molecule (trehalose) to obtain TSiNPs. The successful surface functionalization was confirmed using FTIR, XRD, and EDS. The spherical shape and amorphous nature of the nanoparticles were confirmed using SEM. The TEM image analysis revealed that the size of SiNPs and TSiNPs ranged between 20-50 nm and 200-250 nm, respectively. A novel bioassay experiment designed to study the release of silica and trehalose from nanoparticles elucidated that the TSiNPs improved the release and uptake of silica. Also, trehalose uptake significantly improved after 72 h of application due to enhanced release of trehalose from TSiNPs. Further, this study also aimed to investigate the potential benefits of SiNPs and TSiNPs in promoting the growth and development of plants under salinity stress. In this context, the nanoparticles were applied to the saline-stressed (0, 200, 300 mM) lentil seedlings for the in-planta experiments. The results revealed that both SiNPs and TSiNPs improved the growth of seedlings (shoot, and root length), ionic balance (K
MeSH term(s)	Seedlings/metabolism ; Trehalose ; Lens Plant/metabolism ; Sugars ; Silicon Dioxide ; Hydrogen Peroxide ; Antioxidants/metabolism ; Salt Stress ; Nanoparticles ; Oxidative Stress ; Salinity
Chemical Substances	Trehalose (B8WCK70T7I) ; Sugars ; Silicon Dioxide (7631-86-9) ; Hydrogen Peroxide (BBX060AN9V) ; Antioxidants
Language	English
Publishing date	2023-12-28
Publishing country	France
Document type	Journal Article
ZDB-ID	742978-2
ISSN	1873-2690 ; 0981-9428
ISSN (online)	1873-2690
ISSN	0981-9428
DOI	10.1016/j.plaphy.2023.108309
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Protective effect of probiotics against acetaminophen induced nephrotoxicity

Dua, Tarun Kumar / Palai, Sangita / Roy, Abani / Paul, Paramita

Molecular biology reports. 2022 Aug., v. 49, no. 8

2022

Abstract	Acetaminophen (APAP) is commonly prescribed as an antipyretic and analgesic agent in the practical field. Like every other drug(s), APAP also undergo metabolism by oxidation or conjugation by glucuronate and sulphate to form the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI). Moreover, the NAPQI is detoxified by conjugation with reduced glutathione (GSH). Interestingly, APAP is also metabolized in the kidney by deacetylation reaction in the presence of N-deacetylase enzyme into another severely toxic but minor metabolite, p-aminophenol. Both NAPQI and p-aminophenol shows nephrotoxicity as well as hepatotoxicity. Hence, the long-term therapeutic dose use and unnecessary overdose of APAP are of great concern as prolonged negligence may cost the nephrotoxicity that may lead to uremia and finally to kidney failure. It has recently been investigated that probiotic supplementation inhibits the sequential events associated with APAP-induced nephrotoxicity. This review emphasizes the role of different probiotics that have already been investigated in nephrotoxicity or uremia caused by APAP overdose.
Keywords	acetaminophen ; enzymes ; glutathione ; hepatotoxicity ; imines ; kidneys ; metabolism ; metabolites ; molecular biology ; nephrotoxicity ; overdose ; oxidation ; probiotics ; protective effect ; renal failure ; sulfates ; uremia
Language	English
Dates of publication	2022-08
Size	p. 8139-8143.
Publishing place	Springer Netherlands
Document type	Article
Note	Review
ZDB-ID	186544-4
ISSN	1573-4978 ; 0301-4851
ISSN (online)	1573-4978
ISSN	0301-4851
DOI	10.1007/s11033-022-07534-7
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Evaluation of maceration, microwave, ultrasound-assisted extraction methods on free, esterified and bound phenolic profile and antioxidant activity of black rice.

Rahman, Md Latifur / Mandal, Subhajit / Das, Priya / Ashraf, Gouhar Jahan / Dua, Tarun Kumar / Paul, Paramita / Nandi, Gouranga / Sahu, Ranabir

Zeitschrift fur Naturforschung. C, Journal of biosciences

2023 Volume 78, Issue 11-12, Page(s) 389–398

Abstract: Black rice ( ...

Abstract	Black rice (
MeSH term(s)	Antioxidants/pharmacology ; Antioxidants/chemistry ; Oryza/chemistry ; Anthocyanins ; Microwaves ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Phenols/chemistry ; Flavonoids/chemistry
Chemical Substances	Antioxidants ; Anthocyanins ; Plant Extracts ; Phenols ; Flavonoids
Language	English
Publishing date	2023-09-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	124636-7
ISSN	1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
ISSN (online)	1865-7125
ISSN	0341-0382 ; 0341-0471 ; 0939-5075
DOI	10.1515/znc-2023-0085
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Article ; Online: Green synthesis of copper nanoparticles by using pineapple peel waste: in vitro characterizations and antibacterial potential.

Mitra, Sanchita / Dua, Tarun Kumar / Easmin, Serina / Sarkar, Sucheta / Roy, Arijit Prosad / Sahu, Ranabir / Nandi, Gouranga / Haydar, Md Salman / Roy, Swarnendu / Paul, Paramita

Bioprocess and biosystems engineering

2024

Abstract: A considerable amount of fruit waste is being produced every day worldwide. The green synthesis of metal nanoparticles from fruit peel waste can be an innovative, cost-effective, and eco-friendly alternative to traditional methods. Copper nanoparticles ( ... ...

Abstract	A considerable amount of fruit waste is being produced every day worldwide. The green synthesis of metal nanoparticles from fruit peel waste can be an innovative, cost-effective, and eco-friendly alternative to traditional methods. Copper nanoparticles (CuNPs) were synthesized by a green method using the pineapple peels extract (PLX) and copper sulfate pentahydrate. The formation of CuNPs was visually identified and detected by UV-Visible spectroscopy. The CuNPs were characterized by Fourier-transform infrared (FTIR) spectroscopy, particle size analyzer, scanning electron microscopy (SEM), and X-ray diffraction (XRD). The antioxidant and reducing power of CuNPs were conducted by %DPPH scavenging and electron transfer-based ferric reducing antioxidant power (FRAP) assay, respectively. The antibacterial properties of CuNPs were determined in gram-positive, and gram-negative bacteria. The results showed that the CuNPs were spherical in shape with mean particle size 290.5 nm. The zeta potential of the nanoparticles was found to be - 12.3 mV indicating the instability in the colloidal state. The FTIR study confirmed the peaks of phytochemicals present in the PLX and the nanoparticles supporting the use of pineapple peels as stabilizing, reducing and capping agents. Both the DPPH and reducing power assay depicted that the synthesized CuNPs had significant antioxidant activity. However, the synthesized CuNPs had strong inhibitory capacity against both gram-positive and gram-negative test organisms. Thus, the CuNPS could be used for its viable antibacterial potential to preserve fruits, flowers, and vegetables from bacterial contamination.
Language	English
Publishing date	2024-03-27
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1476357-6
ISSN	1615-7605 ; 1432-0797 ; 1615-7591
ISSN (online)	1615-7605 ; 1432-0797
ISSN	1615-7591
DOI	10.1007/s00449-024-02982-w
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Article ; Online: Formulation of silver nanoparticles using Duabanga grandiflora leaf extract and evaluation of their versatile therapeutic applications.

Das, Priya / Ashraf, Gouhar Jahan / Baishya, Tania / Dua, Tarun Kumar / Paul, Paramita / Nandi, Gouranga / Dutta, Ankita / Limbu, Divya / Kumar, Anoop / Adhikari, Manab Deb / Dewanjee, Saikat / Sahu, Ranabir

Bioprocess and biosystems engineering

2024

Abstract: The current research focused on the green synthesis of silver nanoparticles (AgNPs) using Duabanga grandiflora leaf extract. The green synthesis of AgNPs was confirmed by the surface plasmon resonance band at 453 nm in a UV-Visible analysis. The ... ...

Abstract	The current research focused on the green synthesis of silver nanoparticles (AgNPs) using Duabanga grandiflora leaf extract. The green synthesis of AgNPs was confirmed by the surface plasmon resonance band at 453 nm in a UV-Visible analysis. The formulated AgNPs had a diameter of around 99.72 nm with a spherical shape. Fourier transform infrared (FTIR) spectrum revealed the bio-reducing potential of phytochemicals present in D. grandiflora, which fundamentally influenced the synthesis of AgNPs. Zeta potential, dynamic light scattering (DLS), scanning electron microscopic (SEM), energy-dispersive X-ray spectroscopic (EDX), X-ray diffraction (XRD), and transmission electron microscopic (TEM) analyses were executed to reveal the physicochemical attributes of the AgNPs. The AgNPs were further investigated for their antioxidant, antidiabetic, anticancer, and antibacterial potential. The DPPH free radical assay revealed the potential radical scavenging capacity (IC
Language	English
Publishing date	2024-02-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1476357-6
ISSN	1615-7605 ; 1432-0797 ; 1615-7591
ISSN (online)	1615-7605 ; 1432-0797
ISSN	1615-7591
DOI	10.1007/s00449-024-02975-9
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Article ; Online: High-performance thin-layer chromatography based approach for bioassay and ATR-FTIR spectroscopy for the evaluation of antioxidant compounds from Asparagus racemosus Willd. aerial parts.

Ashraf, Gouhar Jahan / Das, Priya / Dua, Tarun Kumar / Paul, Paramita / Nandi, Gouranga / Sahu, Ranabir

Biomedical chromatography : BMC

2021 Volume 35, Issue 12, Page(s) e5230

Abstract: Asparagus racemosus Willd. is widely used to combat various diseases owing to its medicinal properties. In this study, arial parts of A. racemosus were investigated for their total phenolic content, total flavonoid content and antioxidative potential. A ... ...

Abstract	Asparagus racemosus Willd. is widely used to combat various diseases owing to its medicinal properties. In this study, arial parts of A. racemosus were investigated for their total phenolic content, total flavonoid content and antioxidative potential. A high-performance thin-layer chromatography (HPTLC) method combined with effect-directed-analysis was also developed to screen the antioxidant effects of A. racemosus and quantify biologically active compounds on chromatograms from A. racemosus. Total phenolics (154 mg gallic acid equivalent/g), flavonoid contents (497 mg quercetin/g) and IC
MeSH term(s)	Antioxidants/analysis ; Antioxidants/chemistry ; Asparagaceae/chemistry ; Chromatography, High Pressure Liquid/methods ; Chromatography, Thin Layer/methods ; Flavonoids/analysis ; Flavonoids/chemistry ; Limit of Detection ; Linear Models ; Plant Components, Aerial/chemistry ; Plant Extracts/analysis ; Plant Extracts/chemistry ; Reproducibility of Results ; Spectroscopy, Fourier Transform Infrared/methods
Chemical Substances	Antioxidants ; Flavonoids ; Plant Extracts
Language	English
Publishing date	2021-08-31
Publishing country	England
Document type	Journal Article
ZDB-ID	632848-9
ISSN	1099-0801 ; 0269-3879
ISSN (online)	1099-0801
ISSN	0269-3879
DOI	10.1002/bmc.5230
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