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  1. Article: Tuberculosis: Cliché or Outsider?

    Gama, Leonor / Duarte, Josiana / Martins, Inês / Santos E Silva, Ana / Rita, Henrique

    Cureus

    2024  Volume 16, Issue 2, Page(s) e53956

    Abstract: Tuberculosis is an infectious disease with the potential for multisystemic dissemination, including the central nervous system (CNS). It is difficult to diagnose when the central nervous system is involved. Brain biopsy is the diagnostic method par ... ...

    Abstract Tuberculosis is an infectious disease with the potential for multisystemic dissemination, including the central nervous system (CNS). It is difficult to diagnose when the central nervous system is involved. Brain biopsy is the diagnostic method par excellence for diagnostic confirmation; however, as it is an invasive method and therefore not free from risks, before carrying it out, extra-CNS sites should be privileged, whenever available, through mycobacteriological culture. Here, we present a case of a 34-year-old female with chronic onset of neurologic semiology, whose diagnostic evolution culminated in the diagnosis of cerebral tuberculomas and miliary tuberculosis. Rapid commencement of antibacillaty therapy led to the resolution of the neurologic deficits. Although we face a cliché clinical presentation, in the sense that is very common, the authors consider it outsider because such a presentation is rarely seen in Portugal.
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.53956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Lofgren Syndrome: Achieving an Accurate Diagnosis for Improved Patient Care.

    Gama, Leonor / Santos E Silva, Ana / Valido, Ana / Duarte, Josiana / Rita, Henrique

    Cureus

    2024  Volume 16, Issue 1, Page(s) e51801

    Abstract: Lofgren syndrome is a clinically distinct phenotype of sarcoidosis. It is characterized by the triad of bilateral hilar lymphadenopathy, arthritis (usually the ankles), and fever. We present the case of a 31-year-old male patient who presented with fever ...

    Abstract Lofgren syndrome is a clinically distinct phenotype of sarcoidosis. It is characterized by the triad of bilateral hilar lymphadenopathy, arthritis (usually the ankles), and fever. We present the case of a 31-year-old male patient who presented with fever and edema in both lower limbs, with palpation of subcutaneous nodules. A chest contrast-enhanced computerized axial tomography (CECT) scan revealed perihilar and mediastinal lymphadenopathy. In making the diagnosis, tuberculosis and lymphoma were both ruled out. A mediastinoscopy confirmed Lofgren syndrome. In medicine, a good differential diagnosis is important, as it will help inform the best treatment for the patient.
    Language English
    Publishing date 2024-01-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.51801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Arrhythmogenic Cardiomyopathy as a Late Complication of COVID-19-Induced Myocarditis.

    Campoamor, David / Seixas, Rui / Gama, Leonor / Duarte, Josiana / Araújo, Tiago

    Cureus

    2022  Volume 14, Issue 2, Page(s) e21941

    Abstract: COVID-19 has become a global health problem. So far, more than 281 million COVID-19 cases have been confirmed. The vast majority of patients diagnosed with COVID-19 infection present only with respiratory signs and symptoms. A small amount of patients, ... ...

    Abstract COVID-19 has become a global health problem. So far, more than 281 million COVID-19 cases have been confirmed. The vast majority of patients diagnosed with COVID-19 infection present only with respiratory signs and symptoms. A small amount of patients, however, show signs and symptoms of cardiovascular involvement like a myocardial injury. Myocarditis is one of the possible complications, and cases of clinically suspected myocarditis have been reported in the setting of COVID-19. Herein, we present a case of inflammatory cardiomyopathy, a different type of arrhythmogenic cardiomyopathy, in a 32-year-old man, 40 days after being diagnosed with COVID-19.
    Language English
    Publishing date 2022-02-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ANCA-associated vasculitis after Pfizer-BioNTech COVID-19 vaccination: two case reports.

    Dourado, Eduardo / Silva, Sara Rodrigues / Dias, Filipe / Duarte, Josiana / Inácio, António / Abrantes, Catarina / Cunha, Liliana / Costa, Ana Sofia / Ponte, Cristina / Valido, Ana

    ARP rheumatology

    2023  Volume 2, Issue 2, Page(s) 173–174

    Title translation ANCA-associated vasculitis after Pfizer-BioNTech COVID-19 vaccination: two case reports.
    MeSH term(s) Humans ; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/chemically induced ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-08-22
    Publishing country Portugal
    Document type Case Reports ; Journal Article
    ISSN 2795-4552
    ISSN (online) 2795-4552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A rare and reversible case of heart failure-Hypocalcemia due to hypoparathyroidism.

    de Oliveira Martins Duarte, Josiana / Pestana Pereira, Paula Maria Lobato / Sobral, Ana Sofia Gonçalves / Campoamor Durán, David / da Silva Fernandes, Ana Isabel / Rita, Henrique José Barrelas / de Sousa E Costa, José António

    Clinical case reports

    2019  Volume 7, Issue 10, Page(s) 1932–1934

    Abstract: Physicians should look more carefully for the potential reversible causes of acute heart failure, namely hypoparathyroidism. The recovery of left ventricular function with the treatment of hypoparathyroidism underlines the importance of calcium and the ... ...

    Abstract Physicians should look more carefully for the potential reversible causes of acute heart failure, namely hypoparathyroidism. The recovery of left ventricular function with the treatment of hypoparathyroidism underlines the importance of calcium and the reversibility of this type of cardiomyopathy.
    Language English
    Publishing date 2019-08-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Rectal perforation after barium enema: A case report.

    Duarte, Josiana de Oliveira Martins / Pereira, Paula Maria Lobato Pestana / Sobral, Ana Sofia Gonçalves / de Oliveira, João Pedro Rosa / Rita, Henrique José Barrelas / de Sousa E Costa, José António

    Clinical case reports

    2019  Volume 7, Issue 12, Page(s) 2565–2567

    Abstract: Colorectal perforation after barium enema it is a rare complication, but has a high mortality rate. With the emergence of endoscopic examinations, barium enemas have fallen into disuse and doctors are less aware of its complications. This case is of the ... ...

    Abstract Colorectal perforation after barium enema it is a rare complication, but has a high mortality rate. With the emergence of endoscopic examinations, barium enemas have fallen into disuse and doctors are less aware of its complications. This case is of the utmost importance as failure to recognize it could be fatal.
    Language English
    Publishing date 2019-11-22
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: A reversible case of rapidly progressive dementia-Hypercalcemia due to hyperparathyroidism.

    de Oliveira Martins Duarte, Josiana / Pereira, Paula Maria Lobato Pestana / Lopes, João Nuno Gamito / Goes, Ana Teresa Loução / Durán, David Campoamor / Sobral, Ana Sofia Gonçalves Nunes / Rita, Henrique José Barrelas / de Sousa E Costa, José António

    Clinical case reports

    2019  Volume 7, Issue 12, Page(s) 2571–2574

    Abstract: With an increasingly aging population, it is of extreme importance to exclude potentially reversible dementias, such as hyperparathyroidism with hypercalcemia, in the differential diagnosis of a rapidly progressive dementia. According to literature, this ...

    Abstract With an increasingly aging population, it is of extreme importance to exclude potentially reversible dementias, such as hyperparathyroidism with hypercalcemia, in the differential diagnosis of a rapidly progressive dementia. According to literature, this entity is undervalued and it is highly relevant to be aware of it.
    Language English
    Publishing date 2019-11-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.2564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Late Hospital Arrival for Thrombolysis after Stroke in Southern Portugal: Who Is at Risk?

    Sobral, Sofia / Taveira, Isabel / Seixas, Rui / Vicente, Ana Cláudia / Duarte, Josiana / Goes, Ana Teresa / Durán, David / Lopes, João / Rita, Henrique / Nzwalo, Hipólito

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2018  Volume 28, Issue 4, Page(s) 900–905

    Abstract: Background: Delayed hospital arrival remains the main reason for the low rates of thrombolysis in eligible acute ischemic stroke (AIS) patients. The role of socioeconomic and clinical factors for the prehospital delay of AIS remains poor and has never ... ...

    Abstract Background: Delayed hospital arrival remains the main reason for the low rates of thrombolysis in eligible acute ischemic stroke (AIS) patients. The role of socioeconomic and clinical factors for the prehospital delay of AIS remains poor and has never been studied in Portugal.
    Objectives: Describe the socioeconomic and clinical factors leading to delayed hospital admission of AIS patients eligible to thrombolysis.
    Methods: A case-control study with a consecutive thrombolyzed AIS patients from 2010 to 2015. Controls were patients who did not receive thrombolysis because of late hospital arrival. Logistic regression with stepwise forward regression analysis was used to identify independent predictors of delayed admission to receive thrombolysis with intravenous tissue-type plasminogen activator (rtPA).
    Results: Of the 1247 patients admitted with AIS, 76 (6%) arrived on-time and received intravenous rtPA. Controls were 65.8% (146/222) of the total number of patients included in the study. Overall, the mean age was 73 years (±11, 61), a minority were below 60 years, and 43.7% were women. Being beneficiary of social insertion income (odds ratio [OR]: .286; .124-.662, P = .003), not having any telephone contact (OR: .145; .039-.536, .004) or having exclusive landline (.055; .014-.210, <.001) and posterior circulation stroke (OR: .266; .087-.811, P = .020) decreased the likelihood of hospital arrive on-time rtPA. The use of prehospital ambulance services increased (OR: 6.478; 2.751-15.254, P < .001) the odds of ER on-time arrival for thrombolysis.
    Conclusions: Poverty, lack of stroke awareness, or difficulties in requesting immediate medical help are the main factors implicated in late-hospital admission for thrombolysis in AIS. Stroke awareness campaigns, promotion of activation of national emergency number and stroke code can increase the rate of thrombolysis.
    MeSH term(s) Aged ; Aged, 80 and over ; Case-Control Studies ; Female ; Fibrinolytic Agents/administration & dosage ; Health Knowledge, Attitudes, Practice ; Health Services Accessibility ; Humans ; Infusions, Intravenous ; Male ; Middle Aged ; Patient Admission ; Portugal ; Poverty ; Risk Assessment ; Risk Factors ; Rural Health Services ; Socioeconomic Factors ; Stroke/diagnosis ; Stroke/drug therapy ; Thrombolytic Therapy/methods ; Time Factors ; Time-to-Treatment ; Tissue Plasminogen Activator/administration & dosage ; Transportation of Patients ; Treatment Outcome
    Chemical Substances Fibrinolytic Agents ; Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2018-12-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2018.12.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Good outcome after intravenous thrombolysis for acute stroke in a patient under treatment with dabigatran.

    Diogo, Cátia / Duarte, Josiana / Sobral, Sofia / Pestana, Paula / Nzwalo, Hipólito / Rita, Henrique / Sousa E Costa, José

    The American journal of emergency medicine

    2014  Volume 32, Issue 11, Page(s) 1435.e1–2

    Abstract: The novel oral anticoagulants (NOACs) are indicated for stroke and systemic embolism prophylaxis in patients with nonvalvular atrial fibrillation (AF). Very few cases of intravenous recombinant tissue plasminogen activator (IV rt-PA) in patients under ... ...

    Abstract The novel oral anticoagulants (NOACs) are indicated for stroke and systemic embolism prophylaxis in patients with nonvalvular atrial fibrillation (AF). Very few cases of intravenous recombinant tissue plasminogen activator (IV rt-PA) in patients under treatment with NOACs have been described. The decision to thrombolyze patients under NOACs is complex and requires a balance between the benefits of treatment and the risk of symptomatic hemorrhagic complications.We describe an unusual case of treatment IV rt-PA for acute ischemic stroke in a patient receiving dabigatran for AF. The decision to treat the patient with IV rt-PA was based on the combination of normal coagulation times with the long time elapsed after the last dose of dabigatran, when the drug effect was predictably residual.
    MeSH term(s) Antithrombins/adverse effects ; Antithrombins/therapeutic use ; Atrial Fibrillation/drug therapy ; Benzimidazoles/adverse effects ; Benzimidazoles/therapeutic use ; Dabigatran ; Fibrinolytic Agents/therapeutic use ; Humans ; Male ; Middle Aged ; Stroke/diagnostic imaging ; Stroke/drug therapy ; Tissue Plasminogen Activator/therapeutic use ; Tomography, X-Ray Computed ; beta-Alanine/adverse effects ; beta-Alanine/analogs & derivatives ; beta-Alanine/therapeutic use
    Chemical Substances Antithrombins ; Benzimidazoles ; Fibrinolytic Agents ; beta-Alanine (11P2JDE17B) ; Tissue Plasminogen Activator (EC 3.4.21.68) ; Dabigatran (I0VM4M70GC)
    Language English
    Publishing date 2014-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2014.04.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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