Article ; Online: Renal changes in COVID-19 infection.
Revista da Associacao Medica Brasileira (1992)
2020 Volume 66, Issue 10, Page(s) 1335–1337
Abstract: The COVID-19 (SARS-CoV-2) infection started in China, Wuhan City, Hubei Province, in December 2019, and it was declared a pandemic in mid-March 2020, caused by a new coronavirus strain called SARS-CoV-2. The pathogenesis of kidney injury attributed to ... ...
| Abstract | The COVID-19 (SARS-CoV-2) infection started in China, Wuhan City, Hubei Province, in December 2019, and it was declared a pandemic in mid-March 2020, caused by a new coronavirus strain called SARS-CoV-2. The pathogenesis of kidney injury attributed to SARS- CoV-2 is not well defined yet. Observations show that the kidney damage caused by the new virus mutation is mainly tubular, with impairment of glomerular filtration and high levels of urea and creatinine. A study with seriously ill patients with COVID-19 showed that acute kidney injury was present in 29%. In the face of this evidence, based on recent studies, we can see the great renal contribution as an impact factor in the evolution of COVID-19, not just as a complicator of severity, but maybe part of the initial cascade of the process, requiring a deeper analysis using conventional biomarkers of kidney injury and more aggressive clinical intervention in patients at risk, in an attempt to reduce mortality. |
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| MeSH term(s) | Acute Kidney Injury/virology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/pathology ; Humans ; Kidney/physiopathology ; Kidney/virology ; Pandemics ; Pneumonia, Viral/pathology ; SARS-CoV-2 |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-11-11 |
| Publishing country | Brazil |
| Document type | Journal Article |
| ZDB-ID | 731969-1 |
| ISSN | 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X |
| ISSN (online) | 1806-9282 |
| ISSN | 0104-4230 ; 0004-5241 ; 0102-843X |
| DOI | 10.1590/1806-9282.66.10.1335 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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