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  1. Book ; Online: Micromachines for Dielectrophoresis, Volume II

    Martinez-Duarte, Rodrigo

    2023  

    Keywords Technology: general issues ; dielectrophoresis (DEP) ; semiconducting carbon nanotubes ; carbon nanotube field-effect transistors (CNTFETs) ; electrokinetics of metallodielectric Janus particles ; dipolophoresis ; dielectrophoresis ; induced-charge electrophoresis ; travelling waves and non-uniform fields ; electrorotation ; levitation and stability ; microfluidics ; single cell ; single bacterium ; flow cytometer ; electrophoretic displays ; driving waveform ; damping oscillation ; particles separation ; red saturation ; cell characterization ; cell separation ; interdigitated electrodes (IDEs) ; CMOS-based lab-on-a-chip ; metal droplet driving ; DEP force in narrow volumes ; capacitor charge cycle ; micro-fluidic volumes ; DEP trajectories ; 2D and 3D modelling ; DEP-induced polarizability increase ; conditioned polarization ; lossy dispersive materials ; thermodynamics ; Rayleigh's dissipation function ; law of maximum entropy production (LMEP) ; chondrocyte ; mechanical anisotropy ; tissue engineering ; cell patterning ; Brownian dynamics ; Lab-on-a-chip ; Langevin equation ; optical trap ; Clausius-Mossotti function ; dielectric beta-dispersion ; electrokinetics ; Lorentz cavity ; Maxwell cavity ; molecular dynamics simulations ; proteins ; electric curtain ; electrostatics ; upconcentration ; nanoparticles ; system's perspective ; MatLab® model ; DEP trajectory ; LMEP ; protein dielectrophoresis ; virus trapping ; LOC ; μTAS ; force spectroscopy ; n/a
    Language English
    Size 1 electronic resource (232 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030377343
    ISBN 9783036573007 ; 3036573003
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: COVID-19 em Portugal: a estratégia

    Duarte, Raquel / Lopes, Felisbela / Alves, Filipe / Aguiar, Ana

    2022  

    Keywords Society & culture: general ; Medical study & revision guides & reference material ; COVID-19 ; pandemia ; grupo de especialistas ; desconfinamento
    Language 0|p
    Size 1 Online-Ressource
    Publishing place Braga
    Document type Book ; Online
    Note Portuguese ; Open Access
    HBZ-ID HT021612591
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Micromachines for Dielectrophoresis

    Martinez-Duarte, Rodrigo

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; dielectrophoresis (DEP) ; microparticles ; polystyrene ; chromatography ; interdigitated electrodes ; microfluidic ; separation ; electrowetting display ; driving waveform ; aperture ratio ; exponential function ; time constant ; single-cell microfluidics ; single-cell recovery ; single-cell array ; hydrodynamic trapping ; electrokinetics ; tridimensional electrodes ; mRNA sequencing ; Drop-seq ; induced charge electrophoresis (ICEP) ; Janus particles ; optical trapping ; phase-sensitive detection ; phoretic force spectroscopy ; ICEP motility reversal ; micro-robotics ; dielectrophoresis ; microfluidics ; cell separation ; electrokinetic ; particle focusing ; electrophoretic display ; particle activation ; response speed ; reference grayscale ; cell immobilization ; lab-on-a-chip ; Clausius-Mossotti function ; dielectric spectroscopy ; interfacial polarization ; proteins ; sleeping sickness ; Human African trypanosomiasis ; trypanosoma ; titanium ; curvature-induced ; n/a
    Language 0|e
    Size 1 electronic resource (186 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021610236
    ISBN 9783036543376 ; 3036543376
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Urban Atmospheric Aerosols : Sources, Analysis and Effects

    Duarte, Regina / Duarte, Armando da Costa

    2021  

    Keywords Research & information: general ; Asia-Pacific Economic Cooperation summit ; PM2.5 ; trace elements ; source apportionment ; aerosol optical depth MODIS ; urbanization ; DEM ; spearman rank correlation ; organic aerosol ; water-soluble ions ; organic nitrogen ; aerosol mass spectrometry ; MODIS aerosol product ; Collection 6.1 ; heavy aerosol loading ; AERONET ; submicron ; coarse ; modal structure ; meteorological effect ; particle number size distribution ; seasonal ; diurnal ; resuspension ; household dust ; PM10 ; organic and elemental carbon ; phthalic acid esters ; polycyclic aromatic hydrocarbons ; atmospheric particle-bound mercury ; atmospheric particulate matter ; sources contributions ; Atlantic coastal European region ; toxicity prediction ; urban atmospheric aerosols ; primary organic aerosols ; secondary organic aerosols ; chemical composition ; toxic elements ; particle size characterization ; urban air quality ; indoor air pollution
    Size 1 electronic resource (146 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021044034
    ISBN 9783039439324 ; 3039439324
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Uma Perspetiva sobre o Relatório da OCDE “Health at a Glance 2020”.

    Duarte, Raquel

    Acta medica portuguesa

    2021  Volume 34, Issue 2, Page(s) 84–86

    Title translation A Perspective about the "Health at a Glance 2020" OECD Report.
    MeSH term(s) Air Pollutants/toxicity ; Bed Occupancy/statistics & numerical data ; COVID-19/epidemiology ; Delivery of Health Care/standards ; Europe/epidemiology ; Health Services Accessibility ; Health Status Indicators ; Health Workforce/statistics & numerical data ; Hospitalization ; Humans ; Organisation for Economic Co-Operation and Development ; Pandemics ; Portugal/epidemiology ; Social Determinants of Health
    Chemical Substances Air Pollutants
    Language Portuguese
    Publishing date 2021-02-01
    Publishing country Portugal
    Document type Journal Article
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
    DOI 10.20344/amp.15654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Mechanistic insights into the spontaneous induction of bone formation.

    Ripamonti, Ugo / Duarte, Raquel

    Biomaterials advances

    2024  Volume 158, Page(s) 213795

    Abstract: The grand discovery of morphogens, or "form-generating substances", revealed that tissue morphogenesis is initiated by soluble molecular signals or morphogens primarily belonging to the transforming growth factor-β (TGF-β) supergene family. The ... ...

    Abstract The grand discovery of morphogens, or "form-generating substances", revealed that tissue morphogenesis is initiated by soluble molecular signals or morphogens primarily belonging to the transforming growth factor-β (TGF-β) supergene family. The regenerative potential of bone rests on its extracellular matrix, which is the repository of several morphogens that tightly control cellular differentiating pathways, cellular matrix deposition and remodeling. Alluringly, the matrix also contains specific factors transferred from the heterotopic implanted bone matrices initiating "Tissue Induction", as provocatively described in Nature in 1945. Later, it was found that selected genes and gene products of the TGF-β supergene family singly, synchronously, and synergistically mastermind the induction of bone formation. This review describes the phenomenon of the spontaneous and/or intrinsic osteoinductivity of calcium phosphate-based biomaterials and titanium' constructs without the applications of soluble osteogenetic molecular signals. The review shows the spontaneous induction of bone formation initiated by Ca++ activating stem cell differentiation and up-regulation of bone morphogenetic proteins genes. Expressed gene products are embedded into the concavities of the calcium phosphate-based substrata, initiating bone formation as a secondary response. Pure titanium's substrata do not initiate the spontaneous induction of bone formation. The induction of bone is solely dependent on acid, alkali and heat treatments to form apatite layers on the treated titanium surfaces. The induction of bone formation is achieved exclusively by apatite-based biomaterial surfaces. The hydroxyapatite, in its various forms and geometric configurations, finely tunes the induction of bone formation in heterotopic sites. Cellular differentiation by fine-tuning of the cellular molecular machinery is initiated by specific geometric modularity of the hydroxyapatite substrata that push cellular buttons that start the ripple-like cascade of "Tissue Induction", generating newly formed ossicles with bone marrow in heterotopic extraskeletal sites. The highlighted mechanistic insights into the spontaneous induction of bone formation are a research platform invocating selected molecular elements to construct the induction of bone formation.
    MeSH term(s) Osteogenesis/genetics ; Titanium ; Apatites ; Biocompatible Materials ; Durapatite ; Transforming Growth Factor beta ; Calcium Phosphates
    Chemical Substances Titanium (D1JT611TNE) ; Apatites ; calcium phosphate (97Z1WI3NDX) ; Biocompatible Materials ; Durapatite (91D9GV0Z28) ; Transforming Growth Factor beta ; Calcium Phosphates
    Language English
    Publishing date 2024-02-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 2772-9508
    ISSN (online) 2772-9508
    DOI 10.1016/j.bioadv.2024.213795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial for the Special Issue on Micromachines for Dielectrophoresis, Volume II.

    Martinez-Duarte, Rodrigo

    Micromachines

    2023  Volume 14, Issue 4

    Abstract: Dielectrophoresis (DEP) remains an effective technique for the label-free identification and manipulation of targeted particles ranging from sizes from nano to micrometers and from inert particles to biomolecules and cells [ ... ]. ...

    Abstract Dielectrophoresis (DEP) remains an effective technique for the label-free identification and manipulation of targeted particles ranging from sizes from nano to micrometers and from inert particles to biomolecules and cells [...].
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14040769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial for the Special Issue on Micromachines for Dielectrophoresis.

    Martinez-Duarte, Rodrigo

    Micromachines

    2022  Volume 13, Issue 3

    Abstract: Dielectrophoresis (DEP) remains an effective technique for the label-free identification and manipulation of targeted particles ranging from inert particles to biomolecules and cells [ ... ]. ...

    Abstract Dielectrophoresis (DEP) remains an effective technique for the label-free identification and manipulation of targeted particles ranging from inert particles to biomolecules and cells [...].
    Language English
    Publishing date 2022-03-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi13030417
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Impact of annual TB screening on stone quarry workers in high-incidence Portuguese municipalities.

    Sousa, S / Santos, S / Alves, C M / Gonçalves, G / Carvalho, C / Duarte, R

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2024  Volume 28, Issue 3, Page(s) 136–141

    Abstract: ... SETTING ... The Portuguese municipalities of Penafiel and Marco de Canaveses are high TB incidence areas, where stone quarry workers represent a vulnerable population ... OBJECTIVE ... To assess the ... ...

    Abstract <sec id="st1"><title>SETTING</title>The Portuguese municipalities of Penafiel and Marco de Canaveses are high TB incidence areas, where stone quarry workers represent a vulnerable population.</sec><sec id="st2"><title>OBJECTIVE</title>To assess the annual rate of TB infection (ARI) in stone quarry workers and to compare it with the TB notification rate in the general community.</sec><sec id="st3"><title>DESIGN</title>An annual TB infection screening strategy using interferon-gamma release assay (IGRA) was implemented in 2018 for workers from high-risk stone quarries. A prospective cohort was enrolled and workers screened in periods of 2 years were included. IGRA-positive workers were referred for preventive treatment. ARI was calculated as the proportion of workers with IGRA conversion.</sec><sec id="st4"><title>RESULTS</title>Of the 232 IGRA-negative workers in 2018, 20 tested positive in 2019 (8.6% ARI). Of 171 IGRA-negative workers in 2019, eight tested positive in 2021 (4.7% in 2 years). Two of the 150 IGRA-negative workers in 2021 tested positive in 2022 (1.3% ARI). ARI decreased by 84.9% between 2019 and 2022. In the two municipalities, the TB notification rate declined 23.9% between 2018 and 2021.</sec><sec id="st5"><title>CONCLUSION</title>A more pronounced reduction in ARI was observed among stone quarry workers regularly screened for TB infection compared to the notification rate among the general population in high-incidence municipalities. A screening strategy for high-risk populations, together with enforced community measures, could foster risk reduction in the community.</sec>.
    MeSH term(s) Humans ; Tuberculosis/epidemiology ; Prospective Studies ; Incidence ; Cities ; Portugal/epidemiology ; Interferon-gamma Release Tests ; Mass Screening ; Latent Tuberculosis/diagnosis
    Language English
    Publishing date 2024-03-07
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.23.0350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Screening of refugees from Ukraine for TB: a TBnet survey.

    Argel, M / Conde, M / Vieira, M / Lange, C / Magis-Escurra, C / Duarte, R

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease

    2024  Volume 28, Issue 4, Page(s) 202–203

    MeSH term(s) Humans ; Ukraine/epidemiology ; Refugees ; Antitubercular Agents/therapeutic use ; Mass Screening
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2024-04-02
    Publishing country France
    Document type Journal Article
    ZDB-ID 1385624-8
    ISSN 1815-7920 ; 1027-3719
    ISSN (online) 1815-7920
    ISSN 1027-3719
    DOI 10.5588/ijtld.23.0447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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