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Book ; Online ; E-Book: Phytoremediation of environmental pollutants

Chandra, Ram / Dubey, N.K. / Kumar, Vineet

2018

Author's details	edited by Ram Chandra, N.K. Dubey, Vineet Kumar
Language	English
Size	1 Online-Ressource (xiv, 510 Seiten)
Publisher	CRC Press
Publishing place	Boca Raton, Fla
Publishing country	United States
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT019622017
ISBN	978-1-351-66562-9 ; 9781138062603 ; 1-351-66562-6 ; 113806260X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Nanoencapsulated essential oils as sustainable approach for control of fungal and mycotoxin contamination of food commodities

Tiwari, Shikha / Dubey, N. K.

Current Opinion in Food Science. 2023 May 25, p.101053-

2023 , Page(s) 101053–

Abstract: Contamination of food commodities due to fungal and mycotoxin deteriorates their nutritional quality and also renders potential threat to human health. The adverse effects of different synthetic chemicals used as food preservatives on human health and ... ...

Abstract	Contamination of food commodities due to fungal and mycotoxin deteriorates their nutritional quality and also renders potential threat to human health. The adverse effects of different synthetic chemicals used as food preservatives on human health and environment have compelled the agricultural scientists for search of some safer and sustainable approach to protect food commodities from mycotoxin contamination. During last few years different plant based preservatives specially the essential oil formulations have been recommended as a novel alternative owing to their high volatility, safety and biodegradability. The nanoencapsulation technology has boosted the large scale usage of plant based preservatives overcoming different challenges. The present review deals with the efficacy of botanical preservatives against mold and mycotoxin contamination and emphasizes nanoencapsulation technology as novel approach to enhance their preservative potential.
Keywords	biodegradability ; essential oils ; food contamination ; fungi ; human health ; mycotoxins ; nanocapsules ; nutritive value
Language	English
Dates of publication	2023-0525
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	2797683-X
ISSN	2214-7993
ISSN	2214-7993
DOI	10.1016/j.cofs.2023.101053
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Aflatoxins in food systems: recent advances in toxicology, biosynthesis, regulation and mitigation through green nanoformulations

Tiwari, Shikha / Singh, Bijendra Kumar / Dubey, N. K.

Journal of the Science of Food and Agriculture. 2023 Mar. 15, v. 103, no. 4 p.1621-1630

2023

Abstract: Aflatoxins are hepatocarcinogenic and immunosuppressive mycotoxins mainly synthesized by Aspergillus flavus, A. parasiticus and A. nomius in food systems, causing negative health impacts to humans and other organisms. Aflatoxins contaminate most of the ... ...

Abstract	Aflatoxins are hepatocarcinogenic and immunosuppressive mycotoxins mainly synthesized by Aspergillus flavus, A. parasiticus and A. nomius in food systems, causing negative health impacts to humans and other organisms. Aflatoxins contaminate most of the agri‐products of tropical and subtropical regions due to hot and humid conditions and persist in food items even after food processing steps, causing major threat towards the food security. Different physical and chemical strategies have been applied to mitigate aflatoxin contamination. However, negative impacts of chemical preservatives towards health and environment limit their practical applicability. In this regard, plant‐based preservatives, due to their economical, eco‐friendly and safer profile, are considered as a sustainable approach towards food safety. Incorporation of nanotechnology would enhance the bio‐efficacy of green preservatives by overcoming some of their major challenges, such as volatility. The present review deals with recent information on toxicology and molecular and enzymatic regulatory pathways in the biosynthesis of aflatoxins in food systems. A proper understanding of the role of different genes and regulatory proteins may provide novel preventive strategies for aflatoxin detoxification and also in development of aflatoxin‐resistant food items. The review also emphasizes the role of green nanoformulations as a sustainable approach towards the management of aflatoxins in food systems. In addition, some technological challenges of green nanotechnology have also been discussed in this review, along with highlighting some future perspectives. © 2022 Society of Chemical Industry.
Keywords	Aspergillus flavus ; aflatoxins ; agriculture ; biosynthesis ; food safety ; food security ; immunosuppression ; nanotechnology ; toxicology
Language	English
Dates of publication	2023-0315
Size	p. 1621-1630.
Publishing place	John Wiley & Sons, Ltd.
Document type	Article ; Online
Note	REVIEW
ZDB-ID	184116-6
ISSN	1097-0010 ; 0022-5142
ISSN (online)	1097-0010
ISSN	0022-5142
DOI	10.1002/jsfa.12265
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Encapsulation of carvone in chitosan nanoemulsion as edible film for preservation of slice breads against Aspergillus flavus contamination and aflatoxin B1 production

Das, Somenath / Chaudhari, Anand Kumar / Singh, Vipin Kumar / Dwivedy, Abhishek Kumar / Dubey, N. K.

Food Chemistry. 2024 Jan., v. 430 p.137038-

2024

Abstract: Aspergillus flavus is a common fungus causing bread spoilage by aflatoxin B₁ (AFB₁) production. Essential oil components are considered as effective antifungal agent; however, volatility and oxidative-instability limited their practical applications. The ...

Abstract	Aspergillus flavus is a common fungus causing bread spoilage by aflatoxin B₁ (AFB₁) production. Essential oil components are considered as effective antifungal agent; however, volatility and oxidative-instability limited their practical applications. The aim of this study was to fabricate novel chitosan nanoemulsion film incorporating carvone (carvone-Ne) for protection of bread slices against A. flavus and AFB₁ contamination in storage conditions. The nanoemulsion was characterized by SEM, DLS, XRD, and FTIR analyses accompanying with sustained delivery of carvone. The carvone-Ne displayed better inhibition of A. flavus (0.5 µL/mL) and AFB₁ production (0.4 µL/mL) over unencapsulated carvone along with promising antioxidant activity (p < 0.05). Destruction of ergosterol, mitochondrial-membrane-potential, ions leakage, deformities in methylglyoxal biosynthesis, and in-silico interaction of carvone with Afl-R protein emphasized the antifungal and antiaflatoxigenic mechanisms of action. Further, in-situ preservation potentiality of Carvone-Ne in bread slices with improved gas compositions, and acceptable sensory qualities strengthen its application as innovative packaging material for food preservation.
Keywords	Aspergillus flavus ; aflatoxin B1 ; antioxidant activity ; biosynthesis ; breads ; carvone ; chitosan ; computer simulation ; edible films ; encapsulation ; ergosterol ; essential oils ; food chemistry ; food preservation ; fungi ; nanoemulsions ; spoilage ; Antifungal ; Nanoemulsion ; Packaging ; Methylglyoxal
Language	English
Dates of publication	2024-01
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2023.137038
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Nitric oxide and hydrogen peroxide mediated regulation of chromium (VI) toxicity in wheat seedlings involves alterations in antioxidants and high affinity sulfate transporter

Singh, Samiksha / Dubey, N. K. / Tripathi, Durgesh Kumar / Gupta, Ravi / Singh, Vijay Pratap

Plant Science. 2023 July, v. 332 p.111697-

2023

Abstract: Chromium contamination of the soil is a major scientific concern with reference to crop productivity and human health. In recent years, several approaches are being employed in managing metal toxicity in crop plants. Here, we have investigated about ... ...

Abstract	Chromium contamination of the soil is a major scientific concern with reference to crop productivity and human health. In recent years, several approaches are being employed in managing metal toxicity in crop plants. Here, we have investigated about potential and probable crosstalk of nitric oxide (NO) and hydrogen peroxide (H₂O₂) in mitigating hexavalent chromium [Cr(VI)] toxicity in wheat seedlings. Cr(VI) toxicity reduced the fresh mass and overall growth due to accumulation of reactive oxygen species (ROS) and decreased efficiency of AsA-GSH cycle and downregulation of high affinity sulfate transporter. However, exogenous treatment of NO and H₂O₂ significantly alleviated Cr toxicity. Application of NO and ROS scavengers reversed stress mitigating effects of NO and H₂O₂, respectively suggesting that endogenous NO and H₂O₂ are necessary for rendering Cr toxicity tolerance. Furthermore, NO rescued negative effect of diphenylene iodonium (DPI, NADPH oxidase inhibitor) and H₂O₂ reversed the negative effect of c-PTIO suggesting that they exhibit independent signalling in mitigating Cr stress. Altogether, data indicated that NO and H₂O₂ rendered mitigation of Cr stress by up-regulating enzymes (activity and relative gene expression) and metabolites of AsA-GSH cycle, high affinity sulfate transporter (relative gene expression) and glutathione biosynthesis which collectively controlled occurrence of oxidative stress.
Keywords	NAD(P)H oxidase (H2O2-forming) ; biosynthesis ; chromium ; gene expression ; glutathione ; human health ; hydrogen peroxide ; metabolites ; nitric oxide ; oxidative stress ; soil ; sulfates ; toxicity ; wheat ; Ascorbate-glutathione cycle ; Glutathione biosynthesis ; Growth ; High affinity sulfate transporter ; Oxidative stress indices, Relative gene expression
Language	English
Dates of publication	2023-07
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	742010-9
ISSN	1873-2259 ; 0168-9452
ISSN (online)	1873-2259
ISSN	0168-9452
DOI	10.1016/j.plantsci.2023.111697
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Chitosan based encapsulation of Valeriana officinalis essential oil as edible coating for inhibition of fungi and aflatoxin B1 contamination, nutritional quality improvement, and shelf life extension of Citrus sinensis fruits

Das, Somenath / Chaudhari, Anand Kumar / Singh, Vipin Kumar / Dwivedy, Abhishek Kumar / Dubey, N. K.

International Journal of Biological Macromolecules. 2023 Apr., v. 233 p.123565-

2023

Abstract: In this study, a novel chitosan nanoemulsion coating embedded with Valeriana officinalis essential oil (Ne-VOEO) was synthesized in order to improve the postharvest quality of Citrus sinensis fruits against infesting fungi, and aflatoxin B₁ (AFB₁) ... ...

Abstract	In this study, a novel chitosan nanoemulsion coating embedded with Valeriana officinalis essential oil (Ne-VOEO) was synthesized in order to improve the postharvest quality of Citrus sinensis fruits against infesting fungi, and aflatoxin B₁ (AFB₁) mediated nutritional deterioration. The developed nanoemulsion was characterized through SEM, FTIR, XRD, and DLS analyses. The nanoemulsion showed controlled delivery of VOEO responsible for effective inhibition of Aspergillus flavus, A. niger, A. versicolor, Penicillium italicum, and Fusarium oxysporum growth at 6.5, 5.0, 4.0, 5.5, and 3.5 μL/mL, respectively and AFB₁ production at 5.0 μL/mL. The biochemical and molecular mechanism of aflatoxigenic A. flavus inhibition, and AFB₁ diminution was associated with impairment in ergosterol biosynthesis, methylglyoxal production, and stereo-spatial binding of valerianol in the cavity of Ver-1 protein. During in vivo investigation, Ne-VOEO coating potentially restrained the weight loss, and respiratory rate of C. sinensis fruits with delayed degradation of soluble solids, titrable acidity, pH, and phenolic contents along with maintenance of SOD, CAT, APX activities (p < 0.05) and sensory attributes under specific storage conditions. Based on overall findings, Ne-VOEO nanoemulsion could be recommended as green, and smart antifungal coating agent in prolonging the shelf-life of stored fruits with enhanced AFB₁ mitigation.
Keywords	Aspergillus flavus ; Citrus sinensis ; Fusarium oxysporum ; Penicillium italicum ; Valeriana officinalis ; aflatoxin B1 ; biosynthesis ; chitosan ; encapsulation ; ergosterol ; essential oils ; nanoemulsions ; nutritive value ; pH ; respiratory rate ; shelf life ; titratable acidity ; weight loss ; Valeriana officinalis essential oil ; Nanoemulsion coating ; Antifungal activity
Language	English
Dates of publication	2023-04
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.123565
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: An Appraisal of Ancient Molecule GABA in Abiotic Stress Tolerance in Plants, and Its Crosstalk with Other Signaling Molecules

Suhel, Mohammad / Tajammul Ḥusain / Pandey, Aparna / Singh, Samiksha / Dubey, N. K. / Prasad, Sheo Mohan / Singh, Vijay Pratap

J Plant Growth Regul. 2023 Feb., v. 42, no. 2 p.614-629

2023

Abstract: Gamma-aminobutyric acid (GABA), a non-proteinaceous amino acid, is reported in prokaryotes and eukaryotes, since ancient times. However, it has gained attention in the present time because of its rapid accumulation during stressed conditions in plants as ...

Abstract	Gamma-aminobutyric acid (GABA), a non-proteinaceous amino acid, is reported in prokaryotes and eukaryotes, since ancient times. However, it has gained attention in the present time because of its rapid accumulation during stressed conditions in plants as well as in the cyanobacteria. In plants, it regulates the number of physiological processes such as pollen tube growth, root growth, TCA cycle, N₂-metabolism, and osmoregulation. Several biotic and abiotic stresses prevail in the environment, which lead to enhanced accumulation of reactive oxygen species (ROS) thus causing oxidative damage. However, a rapid increase in the accumulation of GABA during stress in various plant forms like bacteria, cyanobacteria, fungi, and plants indicates its putative role in stress regulation and acclimation. This review summarizes the biosynthesis of GABA, its role in abiotic stress tolerance, and its crosstalk with ROS, nitric oxide, Ca⁺² ions, phytohormones, and polyamines in stress acclimation.
Keywords	Cyanobacteria ; abiotic stress ; acclimation ; biosynthesis ; eukaryotic cells ; gamma-aminobutyric acid ; nitric oxide ; osmoregulation ; plant hormones ; pollen tubes ; polyamines ; prokaryotic cells ; reactive oxygen species ; root growth ; stress tolerance ; tricarboxylic acid cycle
Language	English
Dates of publication	2023-02
Size	p. 614-629.
Publishing place	Springer US
Document type	Article ; Online
Note	Review
ZDB-ID	586787-3
ISSN	1435-8107 ; 0721-7595
ISSN (online)	1435-8107
ISSN	0721-7595
DOI	10.1007/s00344-022-10610-8
Database	NAL-Catalogue (AGRICOLA)

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Book: Plants as a source of natural antioxidants

Dubey, N. K

2015

Author's details	edited by Nawal Kishore Dubey, Banaras Hindu University, India
MeSH term(s)	Antioxidants/therapeutic use ; Antioxidants/pharmacology ; Plants, Edible/chemistry ; Plants, Medicinal/chemistry ; Phytotherapy/methods ; Medicine, Traditional/methods
Language	English
Dates of publication	2015-2015
Size	x, 307 pages :, illustrations ;, 25 cm.
Document type	Book
ISBN	9781780642666 ; 1780642660
Database	Catalogue of the US National Library of Medicine (NLM)

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Book ; Online: Plants as a source of natural antioxidants

Dubey, N. K.

2015

Abstract: This book contains 14 chapters and provides up-to-date basic information on antioxidant plants from different sources and on the role of different abiotic and biotic stresses, endophytes and mycorrhizal fungi in the development of antioxidant compounds ... ...

Author's details	edited by Nawal Kishore Dubey, Banaras Hindu University, India
Abstract	This book contains 14 chapters and provides up-to-date basic information on antioxidant plants from different sources and on the role of different abiotic and biotic stresses, endophytes and mycorrhizal fungi in the development of antioxidant compounds in plants. Some transgenic approaches to the scavenging of reactive oxygen species, and of the antioxidant plants used in different therapeutic systems are discussed and the different medicinal and aromatic plants that have the potential to be used as antioxidants are pointed out.
Keywords	Materia medica, Vegetable. ; Antioxidants/Health aspects. ; Antioxidants/Therapeutic use.
Language	English
Dates of publication	2015-2015
Size	1 online resource (x, 307 pages) :, illustrations
Publisher	CABI
Publishing place	Wallingford, Oxfordshire, UK ; Boston, MA
Document type	Book ; Online
ISBN	9781780642666 ; 1780642660 ; 1780642660 ; 9781780642666
DOI	10.1079/9781780642666.0000
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: High speed homogenization assisted encapsulation of synergistic essential oils formulation: Characterization, in vitro release study, safety profile, and efficacy towards mitigation of aflatoxin B1 induced deterioration in rice samples

Das, Somenath / Chaudhari, Anand Kumar / Singh, Vipin Kumar / Singh, Bijendra Kumar / Dubey, N. K.

Food and Chemical Toxicology. 2022 Nov., v. 169 p.113443-

2022

Abstract: Application of essential oils to mitigate aflatoxin B₁ (AFB₁) contamination in food is a current research hotspot; however, their direct incorporation may cause toxic effects, and changes in food organoleptic properties. This work aimed to synthesize ... ...

Abstract	Application of essential oils to mitigate aflatoxin B₁ (AFB₁) contamination in food is a current research hotspot; however, their direct incorporation may cause toxic effects, and changes in food organoleptic properties. This work aimed to synthesize novel synergistic formulation of Pinus roxburghii, Juniperus communis, and Cupressus sempervirens essential oils by mixture design assay (PJC) and encapsulation of PJC formulation into chitosan nanocomposite (Nm-PJC) with an aim to protect stored rice (Oryza sativa L., prime staple food) against fungi and AFB₁ mediated loss of valuable minerals, macronutrients, and fatty acids. Nm-PJC was characterized through DLS, SEM, FTIR, and XRD analyses, along with controlled delivery from chitosan nanobiopolymer. Encapsulation of synergistic formulation into chitosan-nanomatrix improved antifungal (4.0 μL/mL), antiaflatoxigenic (3.5 μL/mL), and antioxidant activities (P < 0.05). Impairment in ergosterol and methylglyoxal biosynthesis along with in-silico-homology-modeling of major components with Ver-1 and Omt-A proteins advocated chemico-molecular interaction responsible for fungal growth inhibition and AFB₁ secretion. In addition, in-situ efficacy against lipid-peroxidation, fatty acid biodeterioration, and preservation of minerals, macronutrients without affecting organoleptic attributes in rice and high mammalian safety profile (9874.23 μL/kg) suggested practical application of synergistic nanoformulation as innovative smart, and green candidate to mitigate AFB₁ contamination, and shelf-life extension of stored food products.
Keywords	Cupressus sempervirens ; Juniperus communis ; Oryza sativa ; Pinus roxburghii ; aflatoxin B1 ; antioxidants ; biodegradation ; biosynthesis ; chitosan ; encapsulation ; ergosterol ; fatty acids ; fungal growth ; growth retardation ; homogenization ; lipid peroxidation ; mammals ; nanocomposites ; rice ; secretion ; shelf life ; staple foods ; stored grain ; toxicity ; toxicology ; Essential oils ; Nanocomposite ; Antifungal ; Safety
Language	English
Dates of publication	2022-11
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	782617-5
ISSN	1873-6351 ; 0278-6915
ISSN (online)	1873-6351
ISSN	0278-6915
DOI	10.1016/j.fct.2022.113443
Database	NAL-Catalogue (AGRICOLA)

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