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  1. Article ; Online: In Response.

    Blaine, Kevin P / Dudaryk, Roman

    Anesthesia and analgesia

    2023  Volume 136, Issue 6, Page(s) e25

    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.78: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
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  2. Article ; Online: In Response.

    Dudaryk, Roman / Pivalizza, Evan G

    Anesthesia and analgesia

    2022  Volume 135, Issue 2, Page(s) e13–e14

    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In Response.

    Dudaryk, Roman / Pivalizza, Evan G

    Anesthesia and analgesia

    2022  Volume 135, Issue 2, Page(s) e15–e16

    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Evolving science of trauma-induced coagulopathy.

    Fort, Alexander C / Dudaryk, Roman

    International anesthesiology clinics

    2021  Volume 59, Issue 2, Page(s) 25–30

    MeSH term(s) Blood Coagulation Disorders/etiology ; Humans ; Resuscitation
    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 210757-0
    ISSN 1537-1913 ; 0020-5907
    ISSN (online) 1537-1913
    ISSN 0020-5907
    DOI 10.1097/AIA.0000000000000318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 243: Show issues Location:
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  5. Article ; Online: Pro-Con Debate: Viscoelastic Hemostatic Assays Should Replace Fixed Ratio Massive Transfusion Protocols in Trauma.

    Blaine, Kevin P / Dudaryk, Roman

    Anesthesia and analgesia

    2021  Volume 134, Issue 1, Page(s) 21–31

    Abstract: Major trauma patients at risk of traumatic coagulopathy are commonly treated with early clotting factor replacement to maintain hemostasis and prevent microvascular bleeding. In the United States, trauma transfusions are often dosed by empiric, low-ratio ...

    Abstract Major trauma patients at risk of traumatic coagulopathy are commonly treated with early clotting factor replacement to maintain hemostasis and prevent microvascular bleeding. In the United States, trauma transfusions are often dosed by empiric, low-ratio massive transfusion protocols, which pair plasma and platelets in some ratio relative to the red cells, such as the "1:1:1" combination of 1 units of red cells, 1 unit of plasma, and 1 donor's worth of pooled platelets. Empiric transfusion increases the rate of overtransfusion when unnecessary blood products are administered based on a formula and not on at patient's hemostatic profile. Viscoelastic hemostatic assays (VHAs) are point-of-care hemostatic assays that provided detailed information about abnormal clotting pathways. VHAs are used at many centers to better target hemostatic therapies in trauma. This Pro/Con section will address whether VHA guidance should replace empiric fixed ratio protocols in major trauma.
    MeSH term(s) Blood Coagulation Disorders/blood ; Blood Coagulation Factors ; Blood Coagulation Tests/methods ; Blood Transfusion/methods ; Blood Transfusion/standards ; Elasticity ; Emergency Medicine/methods ; Emergency Medicine/standards ; Hemorrhage/therapy ; Hemostasis ; Humans ; Plasma ; Point-of-Care Testing ; Resuscitation ; Transfusion Reaction ; Treatment Outcome ; Viscosity ; Wounds and Injuries/therapy
    Chemical Substances Blood Coagulation Factors
    Language English
    Publishing date 2021-12-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.78: Show issues Location:
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    Zs.MO 149: Show issues

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  6. Article ; Online: Surgical rib fixation in traumatic rib fractures: is it warranted?

    Doben, Andrew R / Schubl, Sebastian D / Dudaryk, Roman

    Current opinion in anaesthesiology

    2022  Volume 35, Issue 2, Page(s) 172–175

    Abstract: Purpose of review: Traumatic chest wall injuries and rib fractures remain a prevalent injury. Despite many advances, these injuries result in high morbidity and mortality. Surgical stabilization of rib fractures (SSRF) is increasing in utilization with ... ...

    Abstract Purpose of review: Traumatic chest wall injuries and rib fractures remain a prevalent injury. Despite many advances, these injuries result in high morbidity and mortality. Surgical stabilization of rib fractures (SSRF) is increasing in utilization with expanding indications. Recent studies have demonstrated that many patients may benefit from surgical intervention.
    Recent findings: Over the past 20 years the indications and timing of SSRF has evolved. Once reserved mainly for the most extreme of injuries, expanding indications demonstrate that even minimally injured patients may benefit from intervention regarding pain control, respiratory complications, and overall mortality.
    Summary: SSRF has become more prevalent with improving outcomes for patients. Understanding the indications will help expand utilization and improve patient outcomes.
    MeSH term(s) Fracture Fixation/adverse effects ; Humans ; Length of Stay ; Rib Fractures/complications ; Rib Fractures/surgery ; Ribs ; Thoracic Injuries/complications
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000001095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2564: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Pro-Con Debate: Prehospital Blood Transfusion-Should It Be Adopted for Civilian Trauma?

    Dudaryk, Roman / Heim, Catherine / Ruetzler, Kurt / Pivalizza, Evan G

    Anesthesia and analgesia

    2022  Volume 134, Issue 4, Page(s) 678–682

    Abstract: Exsanguination is the leading cause of death in severely injured patients; nevertheless, prehospital blood transfusion (PHT) remains a controversial topic. Here, we review the pros and cons of PHT, which is now routine in treatment of military trauma ... ...

    Abstract Exsanguination is the leading cause of death in severely injured patients; nevertheless, prehospital blood transfusion (PHT) remains a controversial topic. Here, we review the pros and cons of PHT, which is now routine in treatment of military trauma patients in the civilian setting. While PHT may improve survival in those who suffer blunt injury or require prolonged transport from the site of injury, PHT for civilian trauma generally is not supported by high-quality evidence. This article was originally presented as a pro-con debate at the 2020 meeting of the European Society of Anesthesiology and Intensive Care.
    MeSH term(s) Blood Transfusion ; Emergency Medical Services ; Exsanguination ; Humans ; Wounds and Injuries/diagnosis ; Wounds and Injuries/therapy ; Wounds, Nonpenetrating
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005747
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Management of Pregnant Trauma Patients: A Narrative Review.

    Lopez, Carmen E / Salloum, Joe / Varon, Albert J / Toledo, Paloma / Dudaryk, Roman

    Anesthesia and analgesia

    2023  Volume 136, Issue 5, Page(s) 830–840

    Abstract: Trauma is the leading nonobstetric cause of maternal death and affects 1 in 12 pregnancies in the United States. Adhering to the fundamentals of the advanced trauma life support (ATLS) framework is the most important component of care in this patient ... ...

    Abstract Trauma is the leading nonobstetric cause of maternal death and affects 1 in 12 pregnancies in the United States. Adhering to the fundamentals of the advanced trauma life support (ATLS) framework is the most important component of care in this patient population. Understanding the significant physiologic changes of pregnancy, especially with regard to the respiratory, cardiovascular, and hematologic systems, will aid in airway, breathing, and circulation components of resuscitation. In addition to trauma resuscitation, pregnant patients should undergo left uterine displacement, insertion of 2 large bore intravenous lines placed above the level of the diaphragm, careful airway management factoring in physiologic changes of pregnancy, and resuscitation with a balanced ratio of blood products. Early notification of obstetric providers, initiation of secondary assessment for obstetric complications, and fetal assessment should be undertaken as soon as possible but without interference to maternal trauma assessment and management. In general, viable fetuses are monitored by continuous fetal heart rate for at least 4 hours or more if abnormalities are detected. Moreover, fetal distress may be an early sign of maternal deterioration. When indicated, imaging studies should not be limited out of fear for fetal radiation exposure. Resuscitative hysterotomy should be considered in patients approaching 22 to 24 weeks of gestation, who arrive in cardiac arrest or present with profound hemodynamic instability due to hypovolemic shock.
    MeSH term(s) Pregnancy ; Female ; Humans ; Cesarean Section/methods ; Resuscitation/adverse effects ; Resuscitation/methods ; Heart Arrest ; Airway Management ; Shock
    Language English
    Publishing date 2023-04-14
    Publishing country United States
    Document type Review ; Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Management of Respiratory Distress Syndrome due to COVID-19 infection

    Navas-Blanco, Jose / Dudaryk, Roman

    BMC anesthesiology, 20(1):177

    2020  

    Abstract: The management of Acute Respiratory Distress Syndrome (ARDS) secondary to the novel Coronavirus Disease 2019 (COVID-19) proves to be challenging and controversial. Multiple studies have suggested the likelihood of an atypical pathophysiology to explain ... ...

    Abstract The management of Acute Respiratory Distress Syndrome (ARDS) secondary to the novel Coronavirus Disease 2019 (COVID-19) proves to be challenging and controversial. Multiple studies have suggested the likelihood of an atypical pathophysiology to explain the spectrum of pulmonary and systemic manifestations caused by the virus. The principal paradox of COVID-19 pneumonia is the presence of severe hypoxemia with preserved pulmonary mechanics. Data derived from the experience of multiple centers around the world have demonstrated that initial clinical efforts should be focused into avoid intubation and mechanical ventilation in hypoxemic COVID-19 patients. On the other hand, COVID-19 patients progressing or presenting into frank ARDS with typical decreased pulmonary compliance, represents another clinical enigma to many clinicians, since routine therapeutic interventions for ARDS are still a subject of debate.
    Keywords COVID-19 ; Severe acute respiratory syndrome coronavirus 2 ; Extracorporeal membrane oxygenation ; Mechanical ventilation ; Acute respiratory distress syndrome ; Coronavirus disease 19 ; Intensive care unit ; covid19
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Management of Respiratory Distress Syndrome due to COVID-19 infection.

    Navas-Blanco, Jose R / Dudaryk, Roman

    BMC anesthesiology

    2020  Volume 20, Issue 1, Page(s) 177

    Abstract: The management of Acute Respiratory Distress Syndrome (ARDS) secondary to the novel Coronavirus Disease 2019 (COVID-19) proves to be challenging and controversial. Multiple studies have suggested the likelihood of an atypical pathophysiology to explain ... ...

    Abstract The management of Acute Respiratory Distress Syndrome (ARDS) secondary to the novel Coronavirus Disease 2019 (COVID-19) proves to be challenging and controversial. Multiple studies have suggested the likelihood of an atypical pathophysiology to explain the spectrum of pulmonary and systemic manifestations caused by the virus. The principal paradox of COVID-19 pneumonia is the presence of severe hypoxemia with preserved pulmonary mechanics. Data derived from the experience of multiple centers around the world have demonstrated that initial clinical efforts should be focused into avoid intubation and mechanical ventilation in hypoxemic COVID-19 patients. On the other hand, COVID-19 patients progressing or presenting into frank ARDS with typical decreased pulmonary compliance, represents another clinical enigma to many clinicians, since routine therapeutic interventions for ARDS are still a subject of debate.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Betacoronavirus ; Biomarkers/metabolism ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Critical Care/methods ; Cross Infection/transmission ; Cytokines/metabolism ; Diagnostic Imaging ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Hypoxia/virology ; Immune System Diseases/virology ; Intubation, Intratracheal ; Neuromuscular Blockade/methods ; Pandemics ; Patient Positioning/methods ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Prone Position/physiology ; Respiration, Artificial/methods ; Respiratory Distress Syndrome/therapy ; Respiratory Distress Syndrome/virology ; SARS-CoV-2 ; Thrombophilia/virology ; Vasodilator Agents/therapeutic use ; COVID-19 Drug Treatment
    Chemical Substances Adrenal Cortex Hormones ; Biomarkers ; Cytokines ; Vasodilator Agents
    Keywords covid19
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2091252-3
    ISSN 1471-2253 ; 1471-2253
    ISSN (online) 1471-2253
    ISSN 1471-2253
    DOI 10.1186/s12871-020-01095-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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