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Article ; Online: Long-term tolerability, immunogenicity and efficacy of Nuwiq

Klukowska, A / Szczepański, T / Vdovin, V / Knaub, S / Bichler, J / Jansen, M / Dzhunova, I / Liesner, R J

Haemophilia : the official journal of the World Federation of Hemophilia

2018  Volume 24, Issue 4, Page(s) 595–603

Abstract: Introduction: Nuwiq: Aim/methods: This study (GENA-13) was an extension of the GENA-03 study in which previously treated children aged 2-12 years with severe haemophilia A received Nuwiq: Results: Of 59 patients enrolled in GENA-03, 49 continued ... ...

Abstract Introduction: Nuwiq
Aim/methods: This study (GENA-13) was an extension of the GENA-03 study in which previously treated children aged 2-12 years with severe haemophilia A received Nuwiq
Results: Of 59 patients enrolled in GENA-03, 49 continued Nuwiq
Conclusion: Long-term treatment with Nuwiq
MeSH term(s) Child ; Child, Preschool ; Factor VIII/adverse effects ; Factor VIII/immunology ; Factor VIII/therapeutic use ; Female ; Hemophilia A/complications ; Hemophilia A/drug therapy ; Hemophilia A/immunology ; Hemorrhage/complications ; Hemorrhage/prevention & control ; Humans ; Male ; Recombinant Proteins/adverse effects ; Recombinant Proteins/immunology ; Recombinant Proteins/therapeutic use ; Safety ; Severity of Illness Index ; Treatment Outcome
Chemical Substances Recombinant Proteins ; Factor VIII (9001-27-8)
Language English
Publishing date 2018-03-26
Publishing country England
Document type Clinical Trial, Phase III ; Journal Article
ZDB-ID 1229713-6
ISSN 1365-2516 ; 1351-8216 ; 1355-0691
ISSN (online) 1365-2516
ISSN 1351-8216 ; 1355-0691
DOI 10.1111/hae.13460
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