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  1. Book ; Thesis: Detektion zirkulierender Tumor-DNA von Myxoiden Liposarkomen durch Next-Generation Sequencing

    Eßer, Julia

    2021  

    Author's details vorgelegt 2021 von Julia Rosemarie Eßer
    Language German
    Size 105 Blätter, Illustrationen, Diagramme
    Publishing place Freiburg im Breisgau
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Albert-Ludwigs-Universität Freiburg im Breisgau, 2021
    HBZ-ID HT021364498
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2022 E 514 order for loan Magazin

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  2. Article ; Online: The TORP-PORP: A Tympanoplasty Technique for Isolated Defects of the Stapes Suprastructure.

    Esser, Julia / Klussmann, Jens Peter / Hüttenbrink, Karl Bernd / Luers, Jan Christoffer

    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

    2024  Volume 45, Issue 3, Page(s) 295–298

    Abstract: Objective: Investigating the outcomes of a surgical approach to treat isolated defects of the stapes suprastructure, using a modified total ossicular replacement prosthesis (TORP) prosthesis as a PORP between the footplate and the incus, effectively ... ...

    Abstract Objective: Investigating the outcomes of a surgical approach to treat isolated defects of the stapes suprastructure, using a modified total ossicular replacement prosthesis (TORP) prosthesis as a PORP between the footplate and the incus, effectively creating a TORP-PORP configuration.
    Patients: Eleven patients (mean age, 37.2 years; 36% male and 64% female) between the years 2007 and 2022.
    Interventions: Therapeutic (ossiculoplasty).
    Main outcome measures: Hearing gain (in dB) in air conduction thresholds at 0.5, 1, 2, 3, and 4 kHz, stability of bone conduction, revision rate.
    Results: Significant improvement in air conduction between the preoperative and the postoperative cohorts (p = 0.002) with a mean postoperative hearing level of 30.00 ± 5.25 dB. The bone conduction remained stable. We encountered no perioperative complications, and there were no revisions surgery.
    Conclusions: The described ossiculoplasty procedure is a safe and effective approach to treat isolated defects of the stapes suprastructure.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Ossicular Prosthesis ; Stapes ; Incus/surgery ; Tympanoplasty/methods ; Ossicular Replacement/methods ; Treatment Outcome ; Retrospective Studies ; Stapes Surgery/methods
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036790-9
    ISSN 1537-4505 ; 1531-7129
    ISSN (online) 1537-4505
    ISSN 1531-7129
    DOI 10.1097/MAO.0000000000004124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Conference proceedings: Leitlinien zum Vestibularisschwannom

    Pollet, Naomi / Eßer, Julia / Klußmann, Jens Peter / Lüers, Jan-Christoffer

    2024  , Page(s) 14

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno14
    Database German Medical Science

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  4. Conference proceedings: Die TORP-PORP: Eine Tympanoplastik-Technik für isolierte Defekte der Stapes-Suprastruktur

    Eßer, Julia / Klußmann, Jens Peter / Hüttenbrink, Karl-Bernd / Lüers, Jan-Christoffer

    2024  , Page(s) 6

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno06
    Database German Medical Science

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  5. Article ; Online: Safety and Efficacy of Laser Enucleation of the Prostate in Elderly Patients - A Narrative Review.

    Yilmaz, Mehmet / Esser, Julia / Suarez-Ibarrola, Rodrigo / Gratzke, Christian / Miernik, Arkadiusz

    Clinical interventions in aging

    2022  Volume 17, Page(s) 15–33

    Abstract: Benign prostatic hyperplasia (BPH) is a common health condition in aging men resulting in lower urinary tract symptoms (LUTS) and low quality of life (QoL). We aimed to review studies on laser enucleation of the prostate (LEP) due to LUTS in elderly ... ...

    Abstract Benign prostatic hyperplasia (BPH) is a common health condition in aging men resulting in lower urinary tract symptoms (LUTS) and low quality of life (QoL). We aimed to review studies on laser enucleation of the prostate (LEP) due to LUTS in elderly patients (>65 years) comparing different age groups, particularly considering functional outcomes, safety, and perioperative complications. A comprehensive search was conducted using the PubMed-MEDLINE, Web of Science, Wiley Online Library and Cochrane Library databases over the last 10 years until 7 October 2021 with the following search terms solely or in combination: "laser enucleation", "prostate", "laser prostatectomy", "aging", "elderly patients", "older patients" and "age". We identified 12 articles for inclusion in our analysis. Five studies focussed mainly on holmium laser enucleation of the prostate (HoLEP), one compared HoLEP to other laser prostatectomy procedures, two studies examined thulium laser enucleation of the prostate (ThuLEP), and two studies focused on GreenLight laser, one study focussed on potassium-titanyl-phosphate (KTP) laser, and another study compared laser prostatectomy to transurethral resection of the prostate (TURP). These studies showed that LEP improved IPSS, Qmax and QoL compared to baseline regardless of age; no significant difference was reported among age groups. Although ASA scores and anticoagulation/antiplatelet therapy rates are higher in elderly patients, studies revealed no significant difference in perioperative complication rates between age groups. Laser enucleation of the prostate is an effective and safe procedure in elderly patients, resulting in good functional outcomes, low morbidity, and few perioperative complications.
    MeSH term(s) Aged ; Humans ; Laser Therapy ; Lasers, Solid-State ; Male ; Prostate/surgery ; Prostatic Hyperplasia/surgery ; Quality of Life ; Transurethral Resection of Prostate ; Treatment Outcome
    Language English
    Publishing date 2022-01-08
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2364924-0
    ISSN 1178-1998 ; 1176-9092
    ISSN (online) 1178-1998
    ISSN 1176-9092
    DOI 10.2147/CIA.S347698
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6742: Show issues Location:
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  6. Article ; Online: Vestibularisschwannom: Faktoren bei der Therapieentscheidung.

    Esser, Julia / Walger, Martin / Pollet, Naomi / Klußmann, Jens Peter / Ruge, Maximilian / Goldbrunner, Roland / Lüers, Jan Christoffer

    Laryngo- rhino- otologie

    2023  Volume 103, Issue 3, Page(s) 176–186

    Abstract: The treatment of vestibular schwannomas (VS) has always posed a challenge for physicians. Three essential treatment principles are available: wait-and-scan, surgery, and stereotactic radiotherapy. In addition to the type of treatment, decisions must be ... ...

    Title translation Vestibular Schwannoma: Factors in Therapy Decision-Making.
    Abstract The treatment of vestibular schwannomas (VS) has always posed a challenge for physicians. Three essential treatment principles are available: wait-and-scan, surgery, and stereotactic radiotherapy. In addition to the type of treatment, decisions must be made regarding the optimal timing of therapy, the combination of different treatment modalities, the potential surgical approach, and the type and intensity of radiation. Factors influencing the therapy decision include tumor location and size or stage, patient age, comorbidities, symptoms, postoperative hearing rehabilitation options, patient preferences, and, not least, the experience of the surgeons and the personnel and technical capabilities of the clinical site. This article begins with a brief overview of vestibular schwannomas, then outlines the fundamental interdisciplinary treatment options, and finally discusses the ENT (ear, nose, and throat)-relevant factors in the therapy decision.
    MeSH term(s) Humans ; Hearing ; Neuroma, Acoustic/diagnosis ; Neuroma, Acoustic/therapy ; Radiosurgery ; Treatment Outcome
    Language German
    Publishing date 2023-12-21
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0340-1588 ; 0935-8943
    ISSN (online) 1438-8685
    ISSN 0340-1588 ; 0935-8943
    DOI 10.1055/a-2222-0878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ul II Zs.95: Show issues Location:
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  7. Article ; Online: The extent of androgen receptor and HER2 expression allows for targeted therapy in most cases of salivary duct carcinoma: analysis of clinical and histopathological data in a tertiary care center.

    Mayer, Marcel / Wolber, Philipp / Prinz, Johanna / Jansen, Louis / Esser, Julia / Shabli, Sami / Quaas, Alexander / Klußmann, Jens Peter / Sharma, Shachi Jenny / Nachtsheim, Lisa / Arolt, Christoph

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2024  

    Abstract: Purpose: The incidence of salivary duct carcinoma (SDC) seems to be underestimated due to inaccurate classification. Further, the frequency of SDC patients with targeted therapy options according to current guidelines is unclear. Therefore, this study ... ...

    Abstract Purpose: The incidence of salivary duct carcinoma (SDC) seems to be underestimated due to inaccurate classification. Further, the frequency of SDC patients with targeted therapy options according to current guidelines is unclear. Therefore, this study aimed at (a) describing the proportion of SDC among salivary gland carcinoma (SGC) before and after reclassification of cases initially classified as adenocarcinoma, not otherwise specified (ANOS); and (b) quantifying the frequency of SDC patients with targeted therapy options.
    Methods: All patients with SDC or ANOS treated in a tertiary care center between 1996 and 2023 were identified. Histopathological diagnosis was verified for patients primarily diagnosed with SDC and reviewed for patients initially diagnosed with ANOS. Clinical data for SDC patients were retrieved from clinical charts. Immunohistochemical (IHC) androgen receptor (AR) and HER2 staining was performed.
    Results: Among 46 SDC, 34 were primarily diagnosed as SDC and 12 had initially been classified as ANOS. The proportion of SDC among SGC was 12.1% and was rising when comparing the time periods 2000-2015 (7.1-11.5%) versus 2016-2023 (15.4-18.1%). Nuclear AR staining in > 70% of tumor cells was found in 56.8% and HER2 positivity (IHC 3 +) in 36.4% of cases. 70.5% of patients showed AR staining in > 70% of tumor cells and/or HER2 positivity and therefore at least one molecular target. 5-year overall and disease-free survival (DFS) were 62.8% and 41.0%. Multivariate Cox regression revealed positive resection margins (HR = 4.0, p = 0.03) as independent negative predictor for DFS.
    Conclusions: The results suggest a rising SDC incidence and show that the extent of the AR and HER2 expression allows for targeted therapy in most SDC cases.
    Language English
    Publishing date 2024-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-024-08627-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Conference proceedings: Bizentrische Analyse des mikrobiologischen Spektrums und der chirurgischen Therapie von Abszessen der Glandula parotidea – eine retrospektive Studie

    Mayer, Marcel / Eßer, Julia / Nachtsheim, Lisa / Walker, Sarah / Lechner, Axel / Canis, Martin / Klußmann, Jens Peter / Wolber, Philipp

    2024  , Page(s) 32

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno32
    Database German Medical Science

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  9. Conference proceedings: Schädigung der makulären retinalen Ganglienzellen bei Patienten mit Riesenzellarteriitis

    Esser, Julia / von der Emde, L / Terheyden, J. / Mercieca, K. / Petzinna, S. / Schäfer, V.S. / Holz, F.G. / Ach, T.

    2024  , Page(s) 24rwa29

    Event/congress 186. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte; Köln; Verein Rheinisch-Westfälischer Augenärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-01-26
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24rwa29
    Database German Medical Science

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  10. Article ; Conference proceedings: Bizentrische Analyse des mikrobiologischen Spektrums und der chirurgischen Therapie von Abszessen der Glandula parotidea – eine retrospektive Studie

    Esser, Julia / Nachtsheim, Lisa / Walker, Sarah / Shabli, Sami / Lechner, Axel / Canis, Martin / Klußmann Jens, Peter / Wolber, Philipp / Mayer, Marcel

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Bonn, Messe Essen, 2024-05-08
    Language German
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1783998
    Database Thieme publisher's database

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