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  1. Article ; Online: Concealed retro-iridic multi-cavitary melanoma revealed by ultrasound biomicroscopy.

    E Hernandez-Emanuelli, Miguel / Bansal, Rolika / Catapano, Thomas M / Shields, Carol L

    Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

    2024  , Page(s) 100049

    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2756329-7
    ISSN 2162-0989 ; 2162-0989
    ISSN (online) 2162-0989
    ISSN 2162-0989
    DOI 10.1016/j.apjo.2024.100049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mesenchymal Stem Cell Therapy for Alzheimer’s Disease

    A. E. Hernández / E. García

    Stem Cells International, Vol

    2021  Volume 2021

    Abstract: Alzheimer’s disease (AD) is a neurodegenerative disease responsible for 60-70% of the 50 million cases of dementia worldwide. It is characterized by neuronal cell death, shrinkage of brain tissue, and progressive cognitive, motor, and behavioral ... ...

    Abstract Alzheimer’s disease (AD) is a neurodegenerative disease responsible for 60-70% of the 50 million cases of dementia worldwide. It is characterized by neuronal cell death, shrinkage of brain tissue, and progressive cognitive, motor, and behavioral impairment, which often leads to death. Although current treatment has helped improve the patient’s quality of life, it has not been able to alter the underlying disease pathology of AD. Studies have shown that mesenchymal stem cells (MSCs)—a group of multipotent stem cells—have the ability to stimulate neuroregeneration and inhibit disease progression. More recently, extracellular vesicles (EVs) from cytokine-preconditioned MSCs have also shown to induce immunomodulatory and neuroprotective effects in AD models. This review will aim to compile pertinent preclinical AD research on transgenic mice as well as clinical trials on MSC-based therapy from diverse sources.
    Keywords Internal medicine ; RC31-1245
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effect of Heart Rate Reserve on Prefrontal Cortical Activation While Dual-Task Walking in Older Adults

    Alka Bishnoi / Gioella N. Chaparro / Manuel E. Hernandez

    International Journal of Environmental Research and Public Health, Vol 19, Iss 47, p

    2022  Volume 47

    Abstract: Hypertension is considered a risk factor for cardiovascular health and non-amnestic cognitive impairment in older adults. While heart rate reserve (HRR) has been shown to be a risk factor for hypertension, how impaired HRR in older adults can lead to ... ...

    Abstract Hypertension is considered a risk factor for cardiovascular health and non-amnestic cognitive impairment in older adults. While heart rate reserve (HRR) has been shown to be a risk factor for hypertension, how impaired HRR in older adults can lead to cognitive impairment is still unclear. The objective of this study was to examine the effects of HRR on prefrontal cortical (PFC) activation under varying dual-task demands in older adults. Twenty-eight older adults (50–82 years of age) were included in this study and divided into higher ( n = 14) and lower ( n = 14) HRR groups. Participants engaged in the cognitive task which was the Modified Stroop Color Word Test (MSCWT) on a self-paced treadmill while walking. Participants with higher HRR demonstrated increased PFC activation in comparison to lower HRR, even after controlling for covariates in analysis. Furthermore, as cognitive task difficulty increased (from neutral to congruent to incongruent to switching), PFC activation increased. In addition, there was a significant interaction between tasks and HRR group, with older adults with higher HRR demonstrating increases in PFC activation, faster gait speed, and increased accuracy, relative to those with lower HRR, when going from neutral to switching tasks. These results provide evidence of a relationship between HRR and prefrontal cortical activation and cognitive and physical performance, suggesting that HRR may serve as a biomarker for cognitive health of an older adult with or without cardiovascular risk.
    Keywords neuroimaging ; cognition ; gait ; Medicine ; R
    Subject code 150
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Developing effective and responsive schools and practitioners. Insights from the science of learning and development

    Laura E. Hernández / Linda Darling-Hammond

    Revista Portuguesa de Investigação Educacional, Iss

    2022  Volume 22

    Abstract: The landscape of 21st century, along with scientific advancements, have significant implications for the way we organize schools and student learning experiences. This conceptual article elevates findings from the science of learning and development ( ... ...

    Abstract The landscape of 21st century, along with scientific advancements, have significant implications for the way we organize schools and student learning experiences. This conceptual article elevates findings from the science of learning and development (SoLD)—a groundbreaking, interdisciplinary research syntheses—to articulate the bourgeoning scientific knowledge of the ways that young people develop and its concrete implications for the ways that schools can be effectively designed to optimize learning, success, and well-being. It concludes with a discussion of emerging research on effectively professionalization to support SoLD-aligned transformation, noting how targeted, ongoing, and immersive professional learning experiences are essential to enabling teacher and school leaders to bring about sustainable and equitable change.
    Keywords Science of learning and development ; School transformation ; Educator/leader professionalization ; Education ; L
    Subject code 370
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Universidade Católica Portuguesa
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Evaluation of the Soil–Water Retention Curve of Arsenic-Contaminated Soil by the Filter Paper Method

    Ismael Vásquez-Nogal / Christian E. Hernández-Mendoza

    Applied Sciences, Vol 12, Iss 2610, p

    2022  Volume 2610

    Abstract: Arsenic is a metalloid frequently found in contaminated sites due to its easy mobilization in the environment. This has attracted the researchers who have studied this phenomenon from an environmental engineering perspective. Although there is evidence ... ...

    Abstract Arsenic is a metalloid frequently found in contaminated sites due to its easy mobilization in the environment. This has attracted the researchers who have studied this phenomenon from an environmental engineering perspective. Although there is evidence indicating that soil contamination impacts its geotechnical behavior, there is no available information about the changes in the soil’s suction after its contamination. The objective of this paper was to evaluate the soil–water retention curve of arsenic-contaminated soil. An unsaturated soil sample was contaminated with arsenic at two different concentrations and a filter paper calibration curve was developed for each contaminant concentration. Soil contamination decreased the BET area and increased its pore sizes. At a saturation rate of 0.8, the matric suction of the contaminated soils decreased (from 1681 kPa to 260 kPa), while the osmotic suction increased (from 23 kPa to 530 kPa), compared with the natural soil’s condition. Furthermore, the soil’s suction values obtained with the ASTM D5298 calibration curve were higher than those obtained using the calibration curve developed for the contaminated state. Thus, to avoid misunderstanding the mechanical behavior of the unsaturated soils under contaminated conditions, the osmotic suction should be considered and evaluated with the corresponding calibration curve.
    Keywords unsaturated soil ; soil suction ; arsenic ; contaminated soil ; environmental geotechnics ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 630
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: LOE renal incidental e inusual

    Carlos E. Hernández O. / María Elena Rojas

    Revista Científica CMDLT, Vol 15, Iss Suplemento (2022)

    2022  

    Abstract: Introducción: Los angiomiolipomas son tumores renales generalmente benignos y muy poco frecuentes. Poseen dos subtipos histológicos, los trifásicos o clásicos, que suelen ser benignos y pueden ser o no asintomáticos, y los del tipo epitelioide que se ... ...

    Abstract Introducción: Los angiomiolipomas son tumores renales generalmente benignos y muy poco frecuentes. Poseen dos subtipos histológicos, los trifásicos o clásicos, que suelen ser benignos y pueden ser o no asintomáticos, y los del tipo epitelioide que se asocian con la enfermedad de esclerosis tuberosa y que cuyo comportamiento es más agresivo y maligno. Discusión: Se hace revisión apropósito de un caso con esta patología, femenina de 56 años quien cursa con LOE renal izquierdo de más de 4 cm, completamente asintomática, por lo que se le realiza Nefroadrenelectomía Radical Izquierda, y tras tomarse muestra para biopsia, se realiza el diagnóstico histológico de Angiomiolipoma Trifásico. Conclusión: Un estudio de imagen de 6 años antes ya describe el LOE en la paciente, sin embargo, se encontraba de menor tamaño. Estos tumores pueden complicarse con hemorragias retroperitoneales, las cuales inducen a un shock hipovolémico, y, por ende, un riesgo para la vida. El estudio de imagen gold standard para su diagnóstico es la tomografía computarizada.
    Keywords Angiomiolipoma ; Biopsia ; Esclerosis Tuberosa ; Riesgo ; patología ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Centro Médico Docente La Trinidad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: LOE renal incidental e inusual

    Carlos E. Hernández O. / María Elena Rojas

    Revista Científica CMDLT, Vol 15, Iss Suplemento (2022)

    2022  

    Abstract: Introducción: Los angiomiolipomas son tumores renales generalmente benignos y muy poco frecuentes. Poseen dos subtipos histológicos, los trifásicos o clásicos, que suelen ser benignos y pueden ser o no asintomáticos, y los del tipo epitelioide que se ... ...

    Abstract Introducción: Los angiomiolipomas son tumores renales generalmente benignos y muy poco frecuentes. Poseen dos subtipos histológicos, los trifásicos o clásicos, que suelen ser benignos y pueden ser o no asintomáticos, y los del tipo epitelioide que se asocian con la enfermedad de esclerosis tuberosa y que cuyo comportamiento es más agresivo y maligno. Discusión: Se hace revisión apropósito de un caso con esta patología, femenina de 56 años quien cursa con LOE renal izquierdo de más de 4 cm, completamente asintomática, por lo que se le realiza Nefroadrenelectomía Radical Izquierda, y tras tomarse muestra para biopsia, se realiza el diagnóstico histológico de Angiomiolipoma Trifásico. Conclusión: Un estudio de imagen de 6 años antes ya describe el LOE en la paciente, sin embargo, se encontraba de menor tamaño. Estos tumores pueden complicarse con hemorragias retroperitoneales, las cuales inducen a un shock hipovolémico, y, por ende, un riesgo para la vida. El estudio de imagen gold standard para su diagnóstico es la tomografía computarizada.
    Keywords Angiomiolipoma ; Biopsia ; Esclerosis Tuberosa ; Riesgo ; patología ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Centro Médico Docente La Trinidad
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Bolivia en la encrucijada de la COVID 19

    Orietta E. Hernández Bermúdez

    Comparative Cultural Studies, Vol 5, Iss

    2020  Volume 10

    Abstract: En noviembre de 2019, un golpe de estado cívico-militar-policial, interrumpió el Proceso de Cambio liderado por Evo Morales Ayma en el Estado Plurinacional de Bolivia. La autoproclamación de Jeanine Añez como presidenta del país dio inicio a un período ... ...

    Abstract En noviembre de 2019, un golpe de estado cívico-militar-policial, interrumpió el Proceso de Cambio liderado por Evo Morales Ayma en el Estado Plurinacional de Bolivia. La autoproclamación de Jeanine Añez como presidenta del país dio inicio a un período oscuro de la historia boliviana caracterizado por inestabilidad y persecución política. El nuevo gabinete ha ido desmontando los logros sociales obtenidos por la administración anterior, sumiendo al país en un escenario de incertidumbre. En este contexto Bolivia enfrenta el reto de la llegada de la COVID 19. En este artículo analizaremos el deficiente manejo de la pandemia por parte del gobierno golpista así como el verdadero trasfondo electoralista de las medidas tomadas por la Presidenta/candidata Jeanine Añez.
    Keywords Proceso de cambio ; golpe de Estado ; Estado Plurinacional ; coronavirus ; gobierno de facto ; Ethnology. Social and cultural anthropology ; GN301-674
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Firenze University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Seagrass mapping using high resolution multispectral satellite imagery

    A. Mederos-Barrera / J. Marcello / F. Eugenio / E. Hernández

    International Journal of Applied Earth Observations and Geoinformation, Vol 113, Iss , Pp 102990- (2022)

    A comparison of water column correction models

    2022  

    Abstract: Satellite remote sensing is an efficient and economical technique for studying coastal bottoms in clear and shallow waters. Accordingly, the main objective of this study is the generation of benthic maps using high spatial resolution multispectral images ...

    Abstract Satellite remote sensing is an efficient and economical technique for studying coastal bottoms in clear and shallow waters. Accordingly, the main objective of this study is the generation of benthic maps using high spatial resolution multispectral images from the WorldView-2/3 satellites. In this context, one of the main challenges consists of eliminating the disturbances caused in the signal by the atmosphere, the sea surface, and the water column. Regarding the water column correction, there is controversy about its effectiveness to improve the results achieved. To assess the impact of the water column correction in seagrass mapping, two coastal areas with different characteristics have been selected. Specifically, an analysis has been carried out consisting of the assessment of the Lyzenga and Sagawa water column correction models to identify the algorithm that provides the best mapping precision and, additionally, to seek if this pre-processing stage is helpful when classifying the seabed. The classification models selected for the study were: Gaussian Naïve Bayes (GNB), Support Vector Machine (SVM), K-Nearest Neighbors (KNN), and Subspace KNN (S-KNN). Machine learning techniques have proven to achieve better results and, in particular, SVM and KNN models provide the best overall accuracy. The results after benthic mapping have demonstrated, that image classification without water column corrections provides better accuracy (95.36% and 99.20%) than using Lyzenga (73.49% and 97.80%) or Sagawa (82.04% and 99.10%), for Case 2 and 1 waters, respectively.
    Keywords High resolution benthic maps ; Seagrass ; Water column correction ; Depth Invariant Index ; Sagawa ; WorldView ; Physical geography ; GB3-5030 ; Environmental sciences ; GE1-350
    Subject code 550
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Magnetless Optical Circulator Based on an Iron Garnet with Reduced Magnetization Saturation

    Gianni Portela / Miguel Levy / Hugo E. Hernandez-Figueroa

    Molecules, Vol 26, Iss 4692, p

    2021  Volume 4692

    Abstract: A three-port circulator for optical communication systems comprising a photonic crystal slab made of a magneto-optical material in which an magnetizing element is not required to keep its magnetic domains aligned is suggested for the first time. By ... ...

    Abstract A three-port circulator for optical communication systems comprising a photonic crystal slab made of a magneto-optical material in which an magnetizing element is not required to keep its magnetic domains aligned is suggested for the first time. By maximizing the incorporation of europium to its molecular formula, the magneto-optical material can remain in the saturated magnetic state even in the absence of an external DC magnetic field. Two- and three-dimensional simulations of the device performed with full-wave electromagnetic solvers based on the finite element method demonstrate that, at the 1550 nm wavelength, the insertion loss, isolation, and reflection levels are equal to or better than −1 dB, −14 dB, and −20 dB, respectively. Since its operation does not require an electromagnet or a permanent magnet, the suggested circulator is much more compact, being able to reach footprints in the range of three orders of magnitude smaller, when compared to other circulator designs referred to in the literature and the presented results can be useful for the design of other nonreciprocal devices with reduced dimensions for optical communication systems.
    Keywords circulators ; magneto-optical materials ; optical communication systems ; Organic chemistry ; QD241-441
    Subject code 535
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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