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  1. Book ; Thesis: Untersuchungen zu Pathogenitätsfaktoren und -mechanismen von Listeria monocytogenes und Shiga Toxin produzierenden Escherichia coli (STEC)

    Ebel, Frank

    1999  

    Author's details vorgelegt von Frank Ebel
    Language German ; English
    Size 68, [110] Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Habil.-Schr., 2000
    Note Enth. außerdem 11 Sonderabdr. aus verschiedenen Zeitschr. - Beitr. teilw. dt., teilw. engl.
    HBZ-ID HT013207574
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 E 3552 order to use in reading room Magazin

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  2. Article ; Online: Monoclonal Antibodies as Tools to Combat Fungal Infections.

    Ulrich, Sebastian / Ebel, Frank

    Journal of fungi (Basel, Switzerland)

    2020  Volume 6, Issue 1

    Abstract: Antibodies represent an important element in the adaptive immune response and a major tool to eliminate microbial pathogens. For many bacterial and viral infections, efficient vaccines exist, but not for fungal pathogens. For a long time, antibodies have ...

    Abstract Antibodies represent an important element in the adaptive immune response and a major tool to eliminate microbial pathogens. For many bacterial and viral infections, efficient vaccines exist, but not for fungal pathogens. For a long time, antibodies have been assumed to be of minor importance for a successful clearance of fungal infections; however this perception has been challenged by a large number of studies over the last three decades. In this review, we focus on the potential therapeutic and prophylactic use of monoclonal antibodies. Since systemic mycoses normally occur in severely immunocompromised patients, a passive immunization using monoclonal antibodies is a promising approach to directly attack the fungal pathogen and/or to activate and strengthen the residual antifungal immune response in these patients.
    Language English
    Publishing date 2020-02-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof6010022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Conference proceedings: Der Kirchenbaumeister Heinrich Hauberrisser

    Ebel, Frank

    Architektur zwischen Historismus und Moderne ; Vorträge zum Symposium am 11. und 12. Oktober 2013 in Vohenstrauß ; mit Werkverzeichnis

    (Schriftenreihe des Oberpfälzer Kulturbundes ; 4)

    2014  

    Event/congress Symposium (2013.10.11-12, Vohenstrauß)
    Author's details Oberpfälzer Kulturbund (Hrsg.). In Zusammenarbeit mit dem Diözesanmuseum Regensburg. [Red.: Frank Ebel]
    Series title Schriftenreihe des Oberpfälzer Kulturbundes ; 4
    Keywords Architektur ; Kirchenbau ; Historismus ; Diözese Regensburg
    Language German
    Size 176 S., Ill., graph. Darst., 21 cm
    Publisher Morsbach
    Publishing place Regensburg
    Document type Book ; Conference proceedings
    Note Literaturangaben
    ISBN 9783937527734 ; 3937527737
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book ; Online ; Thesis: Charakterisierung der Aleuriokonidien von Aspergillus terreus und Untersuchungen von Oberflächenantigenen von Aspergillus fumigatus

    Henß, Isabell [Verfasser] / Ebel, Frank [Akademischer Betreuer]

    2023  

    Author's details Isabell Henß ; Betreuer: Frank Ebel
    Keywords Tiere (Zoologie) ; Animals (Zoology)
    Subject code sg590
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  5. Book ; Online ; Thesis: Untersuchungen zum Sekundärmetabolismus des Schwärzepilzes Stachybotrys chartarum Genotyp S

    Tribelhorn, Katharina [Verfasser] / Ebel, Frank [Akademischer Betreuer]

    2023  

    Author's details Katharina Tribelhorn ; Betreuer: Frank Ebel
    Keywords Tiere (Zoologie) ; Animals (Zoology)
    Subject code sg590
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  6. Article ; Online: A Chemically Defined Medium That Supports Mycotoxin Production by Stachybotrys chartarum Enabled Analysis of the Impact of Nitrogen and Carbon Sources on the Biosynthesis of Macrocyclic Trichothecenes and Stachybotrylactam.

    Tribelhorn, Katharina / Twarużek, Magdalena / Kosicki, Robert / Straubinger, Reinhard K / Ebel, Frank / Ulrich, Sebastian

    Applied and environmental microbiology

    2023  Volume 89, Issue 7, Page(s) e0016323

    Abstract: Stachybotrys chartarum ( ...

    Abstract Stachybotrys chartarum (
    MeSH term(s) Animals ; Humans ; Mycotoxins/toxicity ; Trichothecenes/metabolism ; Stachybotrys/metabolism
    Chemical Substances Mycotoxins ; Trichothecenes
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223011-2
    ISSN 1098-5336 ; 0099-2240
    ISSN (online) 1098-5336
    ISSN 0099-2240
    DOI 10.1128/aem.00163-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 201: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The Novel Monoclonal IgG

    Kakoschke, Tamara Katharina / Kleinemeier, Christoph / Knösel, Thomas / Kakoschke, Sara Carina / Ebel, Frank

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 6

    Abstract: In most cases, invasive aspergillosis (IA) is caused ... ...

    Abstract In most cases, invasive aspergillosis (IA) is caused by
    Language English
    Publishing date 2023-05-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9060622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Galactofuranose (Galf)-containing sugar chain contributes to the hyphal growth, conidiation and virulence of F. oxysporum f.sp. cucumerinum.

    Zhou, Hui / Xu, Yueqiang / Ebel, Frank / Jin, Cheng

    PloS one

    2021  Volume 16, Issue 7, Page(s) e0250064

    Abstract: The ascomycete fungus Fusarium oxysporum f.sp. cucumerinum causes vascular wilt diseases in cucumber. However, few genes related to morphogenesis and pathogenicity of this fungal pathogen have been functionally characterized. BLASTp searches of the ... ...

    Abstract The ascomycete fungus Fusarium oxysporum f.sp. cucumerinum causes vascular wilt diseases in cucumber. However, few genes related to morphogenesis and pathogenicity of this fungal pathogen have been functionally characterized. BLASTp searches of the Aspergillus fumigatus UgmA and galatofuranosyltransferases (Galf-transferases) sequences in the F. oxysporum genome identified two genes encoding putative UDP-galactopyranose mutase (UGM), ugmA and ugmB, and six genes encoding putative Galf-transferase homologs. In this study, the single and double mutants of the ugmA, ugmB and gfsB were obtained. The roles of UGMs and GfsB were investigated by analyzing the phenotypes of the mutants. Our results showed that deletion of the ugmA gene led to a reduced production of galactofuranose-containing sugar chains, reduced growth and impaired conidiation of F. oxysporum f.sp. cucumerinum. Most importantly, the ugmA deletion mutant lost the pathogenicity in cucumber plantlets. Although deletion of the ugmB gene did not cause any visible phenotype, deletion of both ugmA and ugmB genes caused more severe phenotypes as compared with the ΔugmA, suggesting that UgmA and UgmB are redundant and they can both contribute to synthesis of UDP-Galf. Furthermore, the ΔgfsB exhibited an attenuated virulence although no other phenotype was observed. Our results demonstrate that the galactofuranose (Galf) synthesis contributes to the cell wall integrity, germination, hyphal growth, conidiation and virulence in Fusarium oxysporum f.sp. cucumerinum and an ideal target for the development of new anti-Fusarium agents.
    MeSH term(s) Aspergillus nidulans/enzymology ; Cucumis sativus/microbiology ; Fungal Proteins/classification ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Fusarium/genetics ; Fusarium/growth & development ; Fusarium/pathogenicity ; Galactose/analysis ; Galactose/metabolism ; Hyphae/genetics ; Hyphae/growth & development ; Intramolecular Transferases/classification ; Intramolecular Transferases/genetics ; Intramolecular Transferases/metabolism ; Mannans/analysis ; Mannans/metabolism ; Mutagenesis ; Phenotype ; Phylogeny ; Plant Diseases/microbiology ; Virulence/genetics
    Chemical Substances Fungal Proteins ; Mannans ; galactomannan (11078-30-1) ; Intramolecular Transferases (EC 5.4.-) ; UDP-galactopyranose mutase (EC 5.4.99.9) ; Galactose (X2RN3Q8DNE)
    Language English
    Publishing date 2021-07-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0250064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online ; Thesis: Untersuchungen der Atranon- und Satratoxin-Gencluster des Schwärzepilzes Stachybotrys chartarum

    Lang, Katharina [Verfasser] / Ebel, Frank [Akademischer Betreuer]

    2022  

    Author's details Katharina Lang ; Betreuer: Frank Ebel
    Keywords Tiere (Zoologie) ; Animals (Zoology)
    Subject code sg590
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Book ; Online ; Thesis: Zusammenspiel von Thrombozyten und neutrophilen Granulozyten in der Leber unter inflammatorischen Bedingungen

    Hoffknecht, Marie-Louise Laura [Verfasser] / Ebel, Frank [Akademischer Betreuer]

    2022  

    Author's details Marie-Louise Laura Hoffknecht ; Betreuer: Frank Ebel
    Keywords Tiere (Zoologie) ; Animals (Zoology)
    Subject code sg590
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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