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  1. Article ; Online: Iodine in plant-based dairy products is not sufficient in the UK: A market survey.

    Alzahrani, Ali / Ebel, Rainer / Norton, Gareth / Raab, Andrea / Feldmann, Joerg

    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

    2023  Volume 79, Page(s) 127218

    Abstract: Background: Following a well-balanced diet ensures that a person gets all the essential elements for health sustenance. However, in the United Kingdom an increasing proportion of people are transiting to become vegans who exclude animal-based products ... ...

    Abstract Background: Following a well-balanced diet ensures that a person gets all the essential elements for health sustenance. However, in the United Kingdom an increasing proportion of people are transiting to become vegans who exclude animal-based products in their diets. Consequently, people may have a deficit of essential elements such as iodine which is not present in most plant-based meals, additionally iodide fortified table salt is not commonly used in the UK. Without iodine people consuming a vegan diet risk developing iodine deficiency and diseases like goiter.
    Methods: The objective of this study is to determine the difference in iodine content and iodine speciation between plant-based and dairy products. More than 100 market samples of plant-based and dairy milk products were collected in Scotland, UK.
    Results: Iodine concentrations in dairy milk is ten times higher compared to plant-based milks. Similar differences were also apparent for butter, yogurt and cheese. A total of 20% of plant-based milk products were fortified with iodine, however these products had lower iodine concentrations compare to the equivalent dairy products. In this study we calculated that people with average diet have an iodine intake of 226 + /- 103 μg day
    Conclusion: Plant-based dairy consumers are encouraged to use iodine fortified dairy products or use of iodized salt in the UK for home cooking, otherwise there are at risk to get iodine deficient.
    MeSH term(s) Pregnancy ; Animals ; Female ; Lactation ; Dairy Products ; Milk/chemistry ; Diet ; Iodine/analysis ; Nutritional Status ; Malnutrition
    Chemical Substances Iodine (9679TC07X4)
    Language English
    Publishing date 2023-05-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1236267-0
    ISSN 1878-3252 ; 1611-602X ; 0946-672X
    ISSN (online) 1878-3252 ; 1611-602X
    ISSN 0946-672X
    DOI 10.1016/j.jtemb.2023.127218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Arabinofuranosyl Thymine Derivatives-Potential Candidates against Cowpox Virus: A Computational Screening Study.

    Haj Hasan, Ahlam / Preet, Gagan / Milne, Bruce Forbes / Ebel, Rainer / Jaspars, Marcel

    International journal of molecular sciences

    2023  Volume 24, Issue 2

    Abstract: Cowpox is caused by a DNA virus known as the cowpox virus (CPXV) belonging to ... ...

    Abstract Cowpox is caused by a DNA virus known as the cowpox virus (CPXV) belonging to the
    MeSH term(s) Animals ; Humans ; Cowpox virus/genetics ; Cowpox virus/metabolism ; Thymine/metabolism ; Cidofovir/pharmacology ; Ligands ; Molecular Docking Simulation ; Cowpox ; Rodentia
    Chemical Substances Thymine (QR26YLT7LT) ; Cidofovir (JIL713Q00N) ; Ligands
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24021751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: GenX uptake by wheat and rice in flooded and non-flooded soils: a greenhouse experiment.

    Al Zbedy, Amnah / Müller, Viktoria / Kindness, Andrew / Ebel, Rainer / Norton, Gareth J / Feldmann, Joerg

    Environmental science and pollution research international

    2023  Volume 31, Issue 1, Page(s) 1607–1620

    Abstract: GenX (hexafluoropropylene oxide dimer acid) belongs to the group of per- and poly-fluoroalkyl substance (PFAS) compounds introduced to replace perfluorooctanoic acid (PFOA), which has been phased out in industrial and consumer product formulations. While ...

    Abstract GenX (hexafluoropropylene oxide dimer acid) belongs to the group of per- and poly-fluoroalkyl substance (PFAS) compounds introduced to replace perfluorooctanoic acid (PFOA), which has been phased out in industrial and consumer product formulations. While GenX has been investigated in lab animals, there is limited information available regarding its uptake and translocation in wheat and rice. This study reports on a greenhouse experiment in which wheat and rice grown under flooded and non-flooded conditions were exposed to two GenX concentrations in the soil (0.4 mg kg
    MeSH term(s) Animals ; Soil ; Oryza ; Triticum ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Soil Pollutants/analysis
    Chemical Substances Soil ; Soil Pollutants
    Language English
    Publishing date 2023-12-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-31160-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Oesophageal atresia with tracheo-oesophageal fistula: an unusual radiological presentation.

    Patel, Neaha / Ebel, Rainer

    Archives of disease in childhood. Fetal and neonatal edition

    2018  Volume 103, Issue 6, Page(s) F596

    MeSH term(s) Esophageal Atresia/complications ; Esophageal Atresia/diagnostic imaging ; Humans ; Infant, Newborn ; Male ; Radiography ; Tracheoesophageal Fistula/complications ; Tracheoesophageal Fistula/diagnostic imaging
    Language English
    Publishing date 2018-07-20
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2007331-8
    ISSN 1468-2052 ; 1359-2998
    ISSN (online) 1468-2052
    ISSN 1359-2998
    DOI 10.1136/archdischild-2018-315436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Computational Repurposing of Mitoxantrone-Related Structures against Monkeypox Virus: A Molecular Docking and 3D Pharmacophore Study.

    Preet, Gagan / Oluwabusola, Emmanuel T / Milne, Bruce Forbes / Ebel, Rainer / Jaspars, Marcel

    International journal of molecular sciences

    2022  Volume 23, Issue 22

    Abstract: Monkeypox is caused by a DNA virus known as the monkeypox virus (MPXV) belonging to ... ...

    Abstract Monkeypox is caused by a DNA virus known as the monkeypox virus (MPXV) belonging to the
    MeSH term(s) Animals ; Humans ; Monkeypox virus ; Mpox (monkeypox)/diagnosis ; Mpox (monkeypox)/drug therapy ; Molecular Docking Simulation ; Mitoxantrone/pharmacology ; Drug Repositioning ; Pandemics ; COVID-19 ; Receptors, Drug ; Primates ; Rodentia
    Chemical Substances Mitoxantrone (BZ114NVM5P) ; Receptors, Drug
    Language English
    Publishing date 2022-11-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232214287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Terpenes from marine-derived fungi.

    Ebel, Rainer

    Marine drugs

    2010  Volume 8, Issue 8, Page(s) 2340–2368

    Abstract: Terpenes from marine-derived fungi show a pronounced degree of structural diversity, and due to their interesting biological and pharmacological properties many of them have aroused interest from synthetic chemists and the pharmaceutical industry alike. ... ...

    Abstract Terpenes from marine-derived fungi show a pronounced degree of structural diversity, and due to their interesting biological and pharmacological properties many of them have aroused interest from synthetic chemists and the pharmaceutical industry alike. The aim of this paper is to give an overview of the structural diversity of terpenes from marine-derived fungi, highlighting individual examples of chemical structures and placing them in a context of other terpenes of fungal origin. Wherever possible, information regarding the biological activity is presented.
    MeSH term(s) Animals ; Aquatic Organisms/chemistry ; Aquatic Organisms/metabolism ; Biological Products/pharmacology ; Carotenoids/chemistry ; Diterpenes/chemistry ; Fungi/chemistry ; Fungi/metabolism ; Oceans and Seas ; Sesquiterpenes/chemistry ; Sesterterpenes/chemistry ; Steroids/chemistry ; Terpenes/chemistry ; Terpenes/pharmacology ; Triterpenes/chemistry
    Chemical Substances Biological Products ; Diterpenes ; Sesquiterpenes ; Sesterterpenes ; Steroids ; Terpenes ; Triterpenes ; Carotenoids (36-88-4)
    Language English
    Publishing date 2010-08-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md8082340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Pseudomonassin, a New Bioactive Ribosomally Synthesised and Post-Translationally Modified Peptide from

    Miranda, Kevin Jace / Jaber, Saif / Atoum, Dana / Arjunan, Subha / Ebel, Rainer / Jaspars, Marcel / Edrada-Ebel, RuAngelie

    Microorganisms

    2023  Volume 11, Issue 10

    Abstract: Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism, ...

    Abstract Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism,
    Language English
    Publishing date 2023-10-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11102563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Virtual Screening of a Library of Naturally Occurring Anthraquinones for Potential Anti-Fouling Agents.

    Preet, Gagan / Astakala, Rishi Vachaspathy / Gomez-Banderas, Jessica / Rajakulendran, Joy Ebenezer / Hasan, Ahlam Haj / Ebel, Rainer / Jaspars, Marcel

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 3

    Abstract: Marine biofouling is the undesired accumulation of organic molecules, microorganisms, macroalgae, marine invertebrates, and their by-products on submerged surfaces. It is a serious challenge for marine vessels and the oil, gas, and renewable energy ... ...

    Abstract Marine biofouling is the undesired accumulation of organic molecules, microorganisms, macroalgae, marine invertebrates, and their by-products on submerged surfaces. It is a serious challenge for marine vessels and the oil, gas, and renewable energy industries, as biofouling can cause economic losses for these industries. Natural products have been an abundant source of therapeutics since the start of civilisation. Their use as novel anti-fouling agents is a promising approach for replacing currently used, harmful anti-fouling agents. Anthraquinones (AQs) have been used for centuries in the food, pharmaceutical, cosmetics, and paint industries. Citreorosein and emodin are typical additives used in the anti-fouling paint industry to help improve the global problem of biofouling. This study is based on our previous study, in which we presented the promising activity of structurally related anthraquinone compounds against biofilm-forming marine bacteria. To help uncover the anti-fouling potential of other AQ-related structures, 2194 compounds from the COCONUT natural products database were analysed. Molecular docking analysis was performed to assess the binding strength of these compounds to the LuxP protein in
    MeSH term(s) Biofouling/prevention & control ; Molecular Docking Simulation ; Biofilms ; Biological Products/pharmacology ; Anthraquinones/pharmacology
    Chemical Substances Biological Products ; Anthraquinones
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28030995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Heavy Metals, Proximate Analysis and Brine Shrimp Lethality of

    Diyaolu, Oluwatofunmilayo Arike / Attah, Alfred F / Oluwabusola, Emmanuel T / Moody, Jones Olanrewaju / Jaspars, Marcel / Ebel, Rainer

    Foods (Basel, Switzerland)

    2021  Volume 10, Issue 12

    Abstract: ... Vernonia ... ...

    Abstract Vernonia amygdalina
    Language English
    Publishing date 2021-11-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods10122913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Natural product diversity of actinobacteria in the Atacama Desert.

    Rateb, Mostafa E / Ebel, Rainer / Jaspars, Marcel

    Antonie van Leeuwenhoek

    2018  Volume 111, Issue 8, Page(s) 1467–1477

    Abstract: The Atacama Desert of northern Chile is considered one of the most arid and extreme environment on Earth. Its core region was described as featuring "Mars-like" soils that were at one point deemed too extreme for life to exist. However, recent ... ...

    Abstract The Atacama Desert of northern Chile is considered one of the most arid and extreme environment on Earth. Its core region was described as featuring "Mars-like" soils that were at one point deemed too extreme for life to exist. However, recent investigations confirmed the presence of diverse culturable actinobacteria. In the current review, we discuss a total of 46 natural products isolated to date representing diverse chemical classes characterized from different actinobacteria isolated from various locations in the Atacama Desert. Their reported biological activities are also discussed.
    MeSH term(s) Actinobacteria/classification ; Actinobacteria/genetics ; Actinobacteria/physiology ; Anti-Bacterial Agents/biosynthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/isolation & purification ; Biological Products ; Chile ; Computational Biology ; Desert Climate ; Genetic Variation ; Genome, Bacterial/genetics ; Molecular Structure ; Secondary Metabolism/genetics ; Soil Microbiology
    Chemical Substances Anti-Bacterial Agents ; Biological Products
    Language English
    Publishing date 2018-02-14
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 214861-4
    ISSN 1572-9699 ; 0003-6072
    ISSN (online) 1572-9699
    ISSN 0003-6072
    DOI 10.1007/s10482-018-1030-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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