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  1. Book ; Thesis: Die Implantatstabilität des partiellen Kniegelenkersatzes bei femoralen Knochendefekten

    Eckert, Johannes A.

    2018  

    Institution Universität Heidelberg
    Author's details vorgelegt von Johannes Adrian Eckert ; Doktorvater: Herr Prof. Dr. med. Rudi Georg Bitsch
    Language German
    Size 90 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2019
    HBZ-ID HT020628918
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2020 E 1466 order for loan Magazin

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  2. Article ; Online: An optotracer-based antibiotic susceptibility test specifically targeting the biofilm lifestyle of

    Eckert, Johannes A / Rosenberg, Ming / Rhen, Mikael / Choong, Ferdinand X / Richter-Dahlfors, Agneta

    Biofilm

    2022  Volume 4, Page(s) 100083

    Abstract: Antimicrobial resistance is a medical threat of global dimensions. Proper antimicrobial susceptibility testing (AST) for drug development, patient diagnosis and treatment is crucial to counteract ineffective drug use and resistance development. Despite ... ...

    Abstract Antimicrobial resistance is a medical threat of global dimensions. Proper antimicrobial susceptibility testing (AST) for drug development, patient diagnosis and treatment is crucial to counteract ineffective drug use and resistance development. Despite the important role of bacterial biofilms in chronic and device-associated infections, the efficacy of antibiotics is determined using planktonic cultures. To address the need for antibiotics targeting bacteria in the biofilm lifestyle, we here present an optotracing-based biofilm-AST using
    Language English
    Publishing date 2022-09-08
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-2075
    ISSN (online) 2590-2075
    DOI 10.1016/j.bioflm.2022.100083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pulsatile Lavage Improves Tibial Cement Penetration and Implant Stability in Medial Unicompartmental Arthroplasty: A Cadaveric Study.

    Eckert, Johannes A / Bitsch, Rudi G / Schroeder, Stefan / Schwarze, Martin / Jaeger, Sebastian

    The journal of knee surgery

    2021  Volume 36, Issue 4, Page(s) 417–423

    Abstract: Cemented unicompartmental knee arthroplasty (UKA) shows good survivorship and function. However, implant failure, causing the need for revision, can occur. Aseptic loosening is still among the most common reasons for revision. The purpose of this study ... ...

    Abstract Cemented unicompartmental knee arthroplasty (UKA) shows good survivorship and function. However, implant failure, causing the need for revision, can occur. Aseptic loosening is still among the most common reasons for revision. The purpose of this study was to assess the influence of preimplantation lavage technique on tibial cement penetration depth, tibial cement volume, and load to fracture in the tibial component of mobile-bearing UKA. In 10 pairs of fresh frozen human tibiae, cemented UKA was implanted by an experienced surgeon. Tibial components were then implanted, left and right tibiae were randomly allocated to group A or B. Prior to implantation, irrigation was performed with either syringe lavage or pulsatile jet lavage in a standardized manner. Cement surface was 4170.2 mm
    MeSH term(s) Humans ; Arthroplasty, Replacement, Knee/methods ; Bone Cements ; Cadaver ; Cementation/methods ; Knee Prosthesis ; Therapeutic Irrigation/methods ; Tibia/surgery
    Chemical Substances Bone Cements
    Language English
    Publishing date 2021-09-10
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2075354-8
    ISSN 1938-2480 ; 1538-8506 ; 0899-7403
    ISSN (online) 1938-2480
    ISSN 1538-8506 ; 0899-7403
    DOI 10.1055/s-0041-1735310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3867: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Wear and damage in retrieved humeral inlays of reverse total shoulder arthroplasty-where, how much, and why?

    Mueller, Ulrike / Harzi, Amal / Loescher, Raphael / Buelhoff, Matthias / Eckert, Johannes A / Kretzer, Jan Philippe

    Journal of shoulder and elbow surgery

    2020  Volume 30, Issue 8, Page(s) e517–e530

    Abstract: Background: Polyethylene (PE) wear and material degradation have been reported as complications in reverse total shoulder replacements (rTSAs). In this regard, scapular notching is associated with more clinical complications. Therefore, the purposes of ... ...

    Abstract Background: Polyethylene (PE) wear and material degradation have been reported as complications in reverse total shoulder replacements (rTSAs). In this regard, scapular notching is associated with more clinical complications. Therefore, the purposes of the study were to quantify the linear and volumetric wear, as a measure for the amount of removed material, and to qualitatively assess the PE damage modes to describe the material degradation in retrieved rTSA humeral PE inlays that contribute to failure of shoulder replacements. Furthermore, this study aimed to evaluate the effect of scapular notching on PE wear and rim damage of the humeral components.
    Methods: The total study population of 39 humeral inlays contains 2 cohorts that were used for the damage mode analysis and for the wear analysis, respectively. The extent and presence of wear damage modes in 5 defined zones were assessed by a grading system for all PE joint replacements. For quantitative wear analysis the most frequent design (n = 17) was chosen. Using a coordinate-measuring machine and postprocessing software, volumetric wear measurements for the retrieved humeral PE inlays were undertaken. Furthermore, prerevision radiographs were analyzed for scapular notching. Finally, retrieval findings were correlated with clinical and radiographic data to consider the effect of notching and to identify risk of failures for these prostheses.
    Results: Damage on the rim of the humeral PE inlays was more frequent and severe than on the intended articulation surface. Irrespective of the damage mode, the inferior rim zone sustained the greatest amount of wear damage followed by the posterior zone. Burnishing, scratching, pitting, and embedded particles are most likely to occur in the articular surface area, whereas surface deformation, abrasion, delamination and gross material degradation are predominantly present in the inferior and posterior rim zones. The retrieved inlays exhibited a mean volumetric wear rate of 296.9 mm³/yr ± 87.0 mm³/yr. However, if the notched and non-notched components were compared, a significant higher volumetric wear rate (296.5 ± 106.1 mm³/yr) was found for the notched components compared to the non-notched group (65.7 ± 7.4 mm³/yr). Generally, there was a significantly greater incidence of damage and greater amount of wear if scapular notching occurred.
    Conclusion: The notched components showed a 5-fold increase in PE wear rate. Therefore, scapular notching has a strong effect on PE damage and wear. If scapular notching can be clinically avoided, the PE wear performance is in a similar magnitude as found for hip and knee replacements.
    MeSH term(s) Arthroplasty, Replacement/adverse effects ; Arthroplasty, Replacement, Shoulder/adverse effects ; Humans ; Humerus ; Polyethylene ; Prosthesis Design ; Scapula ; Shoulder Joint/diagnostic imaging ; Shoulder Joint/surgery
    Chemical Substances Polyethylene (9002-88-4)
    Language English
    Publishing date 2020-11-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1170782-3
    ISSN 1532-6500 ; 1058-2746
    ISSN (online) 1532-6500
    ISSN 1058-2746
    DOI 10.1016/j.jse.2020.10.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3973: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Pulsatile Lavage Improves Tibial Cement Penetration and Implant Stability in Medial Unicompartmental Arthroplasty: A Cadaveric Study

    Eckert, Johannes A. / Bitsch, Rudi G. / Schroeder, Stefan / Schwarze, Martin / Jaeger, Sebastian

    The Journal of Knee Surgery

    2021  Volume 36, Issue 04, Page(s) 417–423

    Abstract: Cemented unicompartmental knee arthroplasty (UKA) shows good survivorship and function. However, implant failure, causing the need for revision, can occur. Aseptic loosening is still among the most common reasons for revision. The purpose of this study ... ...

    Abstract Cemented unicompartmental knee arthroplasty (UKA) shows good survivorship and function. However, implant failure, causing the need for revision, can occur. Aseptic loosening is still among the most common reasons for revision. The purpose of this study was to assess the influence of preimplantation lavage technique on tibial cement penetration depth, tibial cement volume, and load to fracture in the tibial component of mobile-bearing UKA. In 10 pairs of fresh frozen human tibiae, cemented UKA was implanted by an experienced surgeon. Tibial components were then implanted, left and right tibiae were randomly allocated to group A or B. Prior to implantation, irrigation was performed with either syringe lavage or pulsatile jet lavage in a standardized manner. Cement surface was 4170.2 mm 2 (3271.6–5497.8 mm 2 ) in the syringe lavage group, whereas the jet lavage group showed 4499.3 mm 2 (3354.3–5809.1 mm 2 ); cement volume was significantly higher as well (4143.4 mm 3 (2956.6–6198.6 mm 3 ) compared with 5936.9 mm 3 (3077.5–8183.1 mm 3 )). Cement penetration depth was 2.5 mm (1.7–3.2 mm) for the jet lavage, and 1.8 mm (1.2–2.4 mm) for the syringe lavage. The mean fracture load was 4680 N in the jet lavage group and 3800 N in the syringe lavage group ( p  = 0.001). Subsidence was significantly higher for syringe lavage. This study suggests a correlation of cement penetration depth and cement volume to implant failure in the tibial component of a UKA using a cadaveric model. The type of bone lavage most likely influences these two key parameters.
    Keywords oxford unicompartmental knee replacement ; lavage ; cementing
    Language English
    Publishing date 2021-09-10
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2075354-8
    ISSN 1938-2480 ; 1538-8506 ; 0899-7403
    ISSN (online) 1938-2480
    ISSN 1538-8506 ; 0899-7403
    DOI 10.1055/s-0041-1735310
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3867: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Can intraoperative measurement of bone quality help in decision making for cementless unicompartmental knee arthroplasty?

    Eckert, Johannes A / Jaeger, Sebastian / Klotz, Matthias C / Schwarze, Martin / Bitsch, Rudi G

    The Knee

    2018  Volume 25, Issue 4, Page(s) 609–616

    Abstract: Background: In uncemented total hip arthroplasty (THA), low bone mineral density (BMD) is associated with aseptic loosening. BMD is usually assessed via dual-energy X-ray absorptiometry (DXA) or quantitative computed tomography, which takes time and ... ...

    Abstract Background: In uncemented total hip arthroplasty (THA), low bone mineral density (BMD) is associated with aseptic loosening. BMD is usually assessed via dual-energy X-ray absorptiometry (DXA) or quantitative computed tomography, which takes time and exposes patients to radiation. Due to its low risk profile, intraoperative measurement of the trabecular stability might be a useful alternative to DXA.
    Methods: In 24 human femora, BMD was analysed using DXA at the femoral necks and the knees. Performing the standard Oxford Unicompartmental Knee Arthroplasty (OUKA) implantation procedure, a wingblade (DensiProbe) coupled to a torque probe was used to evaluate the trabecular peak torque. The standard procedure was modified: before the completion of the central peg drill hole, the DensiProbe was inserted into the pre-drilled hole and then turned until a loss of resistance was achieved. The obtained data was then correlated with BMD at the femoral neck as well as the knee.
    Results: In all tested regions, a higher peak torque was observed in correlation with a higher BMD.
    Conclusions: As demonstrated, the DensiProbe can be a helpful tool to assess the bone quality intraoperatively in OUKA. It can be a valuable decision guidance when faced with choosing between a cemented and a cementless implant. Due to the fact that the central peg hole of the OUKA can be used for the procedure, no additional risk for the patient exists, while the additional work for the surgeon is minimal.
    MeSH term(s) Absorptiometry, Photon/methods ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Knee/methods ; Bone Cements ; Bone Density/physiology ; Cadaver ; Decision Making ; Female ; Femur/diagnostic imaging ; Femur/surgery ; Humans ; Knee Joint/surgery ; Knee Prosthesis ; Male ; Middle Aged ; Torque
    Chemical Substances Bone Cements
    Language English
    Publishing date 2018-05-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1200476-5
    ISSN 1873-5800 ; 0968-0160
    ISSN (online) 1873-5800
    ISSN 0968-0160
    DOI 10.1016/j.knee.2018.03.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4043: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: A semi high-throughput method for real-time monitoring of curli producing

    Choong, Ferdinand X / Huzell, Smilla / Rosenberg, Ming / Eckert, Johannes A / Nagaraj, Madhu / Zhang, Tianqi / Melican, Keira / Otzen, Daniel E / Richter-Dahlfors, Agneta

    Biofilm

    2021  Volume 3, Page(s) 100060

    Abstract: Biofilms enable bacteria to colonize numerous ecological niches. Bacteria within a biofilm are protected by the extracellular matrix (ECM), of which the fibril-forming amyloid protein curli and polysaccharide cellulose are major components in members ... ...

    Abstract Biofilms enable bacteria to colonize numerous ecological niches. Bacteria within a biofilm are protected by the extracellular matrix (ECM), of which the fibril-forming amyloid protein curli and polysaccharide cellulose are major components in members of
    Language English
    Publishing date 2021-11-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-2075
    ISSN (online) 2590-2075
    DOI 10.1016/j.bioflm.2021.100060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fretting and Corrosion in Modular Shoulder Arthroplasty: A Retrieval Analysis.

    Eckert, Johannes A / Mueller, Ulrike / Jaeger, Sebastian / Panzram, Benjamin / Kretzer, J Philippe

    BioMed research international

    2016  Volume 2016, Page(s) 1695906

    Abstract: Tribocorrosion in taper junctions of retrieved anatomic shoulder arthroplasty implants was evaluated. A comparison of the tribocorrosion between cobalt-chromium and titanium alloy stems was conducted and the observations were correlated with the ... ...

    Abstract Tribocorrosion in taper junctions of retrieved anatomic shoulder arthroplasty implants was evaluated. A comparison of the tribocorrosion between cobalt-chromium and titanium alloy stems was conducted and the observations were correlated with the individual's clinical data. Adverse effects caused by metal debris and subsequent elevated serum metal ion levels are frequently reported in total hip arthroplasty. In total shoulder arthroplasty, to date only a small number of retrieval analyses are available and even fewer address the issue of tribocorrosion at the taper junctions. A total of 36 retrieved hemiarthroplasties and total shoulder arthroplasties were assessed using the modified Goldberg score. The prevalence of fretting and corrosion was confirmed in this cohort. Titanium stems seem to be more susceptible to damage caused by tribocorrosion than cobalt-chromium stems. Furthermore, stemless designs offered less tribocorrosion at the taper junction than stemmed designs. A weak correlation between time to revision and increased levels of tribocorrosion was seen. Whether or not tribocorrosion can lead to adverse clinical reactions and causes failure of shoulder arthroplasties remains to be examined.
    MeSH term(s) Aged ; Aged, 80 and over ; Arthroplasty/methods ; Chromium Alloys/therapeutic use ; Female ; Hemiarthroplasty/methods ; Hip/surgery ; Humans ; Male ; Middle Aged ; Shoulder/surgery ; Titanium/therapeutic use
    Chemical Substances Chromium Alloys ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2016/1695906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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