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  1. Book ; Online: Einführung von medizintechnischen Innovationen im Krankenhaus

    Panteli, Dimitra / Henschke, Cornelia / Eckhardt, Helene / Busse, Reinhard

    Eine systematische Analyse von 27 neuen Untersuchungs- und Behandlungsmethoden zwischen 2005 und 2017: Diffusion, Evidenz und Forschungsaktivitäten

    (Working papers in health services research)

    2023  

    Series title Working papers in health services research
    Keywords Public health & preventive medicine ; health technologies ; benefit assessment ; evidenced based medicine ; inpatient care ; regulation
    Language German
    Size 1 electronic resource (306 pages)
    Publisher Universitätsverlag der Technischen Universität Berlin
    Publishing place Berlin
    Document type Book ; Online
    Note German
    HBZ-ID HT030374979
    ISBN 9783798332614 ; 3798332614
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: PET/PET-CT Evidenz zum Bedarf und zur Planung in Deutschland und Österreich: Update 2018

    Fuchs, Sabine / Grössmann, Nicole / Eckhardt, Helene / Busse, Reinhard / Wild, Claudia

    (Working papers in health policy and management ; Volume 12)

    2019  

    Author's details Sabine Fuchs, Nicole Grössmann, Helene Eckhardt, Reinhard Busse, Claudia Wild
    Series title Working papers in health policy and management ; Volume 12
    Collection
    Keywords Bedarfsplanung ; Entzündungserkrankungen ; Neurologie ; Nutzenbewertung ; Onkologie ; PET/PET-CT ; Positronen-Emissions-Tomographie ; evidence‐based medicine ; evidenzbasierte Medizin ; health technology assessment ; infections ; inflammatory indications ; needs-based planning ; neurology ; oncology ; positron emission tomography ; Deutschland ; Österreich ; Positronen-Emissions-Tomografie ; Computertomografie
    Subject Computertomographie ; CT ; Tomometrie ; Durchstrahlungscomputertomographie ; Durchstrahlungscomputertomografie ; Transmissionscomputertomographie ; Transmissionscomputertomografie ; Computerlaminographie ; Computerlaminografie ; CAT ; Computed axial tomography ; Computertomogramm ; Positronen-Emissions-Tomographie ; PET
    Subject code 616.075750943 ; 616.0757509436
    Language German
    Size 179 Seiten, 30 cm
    Publisher Universitätsverlag der TU Berlin
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT020431878
    ISBN 978-3-7983-3038-2 ; 3-7983-3038-7 ; 9783798330399 ; 3798330395
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 772 available for loan (reading room) Lesesaal EG

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  3. Article ; Online: Cost-effectiveness of prehabilitation of elderly frail or pre-frail patients prior to elective surgery (PRAEP-GO) versus usual care - Protocol for a health economic evaluation alongside a randomized controlled trial.

    Eckhardt, Helene / Quentin, Wilm / Silzle, Julia / Busse, Reinhard / Rombey, Tanja

    BMC geriatrics

    2024  Volume 24, Issue 1, Page(s) 231

    Abstract: Background: Prehabilitation aims to improve patients' functional capacity before surgery to reduce perioperative complications, promote recovery and decrease probability of disability. The planned economic evaluation is performed alongside a large ... ...

    Abstract Background: Prehabilitation aims to improve patients' functional capacity before surgery to reduce perioperative complications, promote recovery and decrease probability of disability. The planned economic evaluation is performed alongside a large German multi-centre pragmatic, two-arm parallel-group, randomized controlled trial on prehabilitation for frail elderly patients before elective surgery compared to standard care (PRAEP-GO RCT). The aim is to determine the cost-effectiveness and cost-utility of prehabilitation for frail elderly before an elective surgery.
    Methods: The planned health economic evaluation comprises cost-effectiveness, and cost-utility analyses. Analyses are conducted in the German context from different perspectives including the payer perspective, i.e. the statutory health insurance, the societal perspective and the health care provider perspective. Data on outcomes and costs, are collected alongside the ongoing PRAEP-GO RCT. The trial population includes frail or pre-frail patients aged ≥70 years with planned elective surgery. The intervention consists of frailty screening (Fried phenotype), a shared decision-making conference determining modality (physiotherapy and unsupervised physical exercises, nutrition counselling, etc.) and setting (inpatient, day care, outpatient etc.) of a 3-week individual multimodal prehabilitation prior to surgery. The control group receives standard preoperative care. Costs include the intervention costs, the costs of the index hospital stay for surgery, and health care resources consumed during a 12-month follow-up. Clinical effectiveness outcomes included in the economic evaluation are the level of care dependency, the degree of disability as measured by the WHO Disability Assessment Schedule 2.0 (WHODAS 2.0), quality-adjusted life years (QALY) derived from the EQ-5D-5L and the German utility set, and complications occurring during the index hospital stay. Each adopted perspective considers different types of costs and outcomes as outlined in the protocol. All analyses will feature Intention-To-Treat analysis. To explore methodological and parametric uncertainties, we will conduct probabilistic and deterministic sensitivity analyses. Subgroup analyses will be performed as secondary analyses.
    Discussion: The health economic evaluation will provide insights into the cost-effectiveness of prehabilitation in older frail populations, informing decision-making processes and contributing to the evidence base in this field. Potential limitation includes a highly heterogeneous trial population.
    Trial registration: PRAEP-GO RCT: NCT04418271; economic evaluation: OSF ( https://osf.io/ecm74 ).
    MeSH term(s) Aged ; Humans ; Cost-Benefit Analysis ; Frail Elderly ; Preoperative Exercise ; Inpatients ; Outpatients ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-024-04833-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: International strategies, experiences, and payment models to incentivise day surgery.

    Kreutzberg, Anika / Eckhardt, Helene / Milstein, Ricarda / Busse, Reinhard

    Health policy (Amsterdam, Netherlands)

    2023  Volume 140, Page(s) 104968

    Abstract: The importance of day surgery as a less costly alternative compared to conventional inpatient hospital stays is growing internationally. The rate of day surgery activities has increased across Europe. However, this trend has been heterogeneous across ... ...

    Abstract The importance of day surgery as a less costly alternative compared to conventional inpatient hospital stays is growing internationally. The rate of day surgery activities has increased across Europe. However, this trend has been heterogeneous across countries, and might still be below its potential. Since payment systems affect how providers offer care, they represent a policy instrument to further increase the rate of day surgeries. In this paper, we review international strategies to promote day surgery with a particular focus on payment models for 13 OECD countries (Australia, Austria, Canada, Denmark, England, Estonia, Finland, France, Germany, Netherlands, Norway, Sweden, Switzerland). We conduct a cross-country comparison based on an email survey of health policy experts and a comprehensive literature review of peer-reviewed papers and grey literature. Our research shows that all countries aim to strengthen day surgery activity to increase health system efficiency. Several countries used financial and non-financial policy measures to overcome misaligned incentive structures and promote day surgery activity. Financial incentives for day surgery can serve as a policy instrument to promote change. We recommend embedding these incentives in a comprehensive approach of restructuring health systems. In addition, we encourage countries to monitor and evaluate the effect of changes to payment systems on day surgeries to allow for more informed decision-making.
    MeSH term(s) Humans ; Ambulatory Surgical Procedures ; Europe ; Health Policy ; Germany ; Netherlands
    Language English
    Publishing date 2023-12-17
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 605805-x
    ISSN 1872-6054 ; 0168-8510
    ISSN (online) 1872-6054
    ISSN 0168-8510
    DOI 10.1016/j.healthpol.2023.104968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2250: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Correction: Digital health applications and the fast-track pathway to public health coverage in Germany: challenges and opportunities based on first results.

    Lantzsch, Hendrikje / Eckhardt, Helene / Campione, Alessandro / Busse, Reinhard / Henschke, Cornelia

    BMC health services research

    2023  Volume 23, Issue 1, Page(s) 637

    Language English
    Publishing date 2023-06-14
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-023-09679-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Conference proceedings: Aufnahme der Prähabilitation vor elektiven Operationen bei Patient*innen ab 70 Jahren mit Gebrechlichkeitssyndrom in die Regelversorgung – Protokoll einer Potenzialanalyse

    Felgner, Susanne / Eckhardt, Helene / Quentin, Wilm / Rombey, Tanja

    2023  , Page(s) 23dkvf004

    Event/congress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-10-02
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkvf004
    Database German Medical Science

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  7. Conference proceedings: Ist Prähabilitation gegenüber der Standardversorgung vor einer elektiven Operation kosteneffektiv? Ein systematisches Review von gesundheitsökonomischen Evaluationen

    Rombey, Tanja / Eckhardt, Helene / Kiselev, Jörn / Quentin, Wilm

    2023  , Page(s) 23ebmV5–03

    Event/congress 24. Jahrestagung des Netzwerks Evidenzbasierte Medizin; Gesundheit und Klima – EbM für die Zukunft; Potsdam; Netzwerk Evidenzbasierte Medizin e.V.; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-03-21
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23ebm023
    Database German Medical Science

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  8. Conference proceedings: Ist Prähabilitation gegenüber der Standardversorgung vor einer elektiven Operation kosteneffektiv? Ein systematisches Review von gesundheitsökonomischen Evaluationen

    Eckhardt, Helene / Rombey, Tanja / Quentin, Wilm

    2023  , Page(s) 23dkvf571

    Event/congress 22. Deutscher Kongress für Versorgungsforschung (DKVF); Berlin; Deutsches Netzwerk Versorgungsforschung; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-10-02
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23dkvf571
    Database German Medical Science

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  9. Article ; Online: Digital health applications and the fast-track pathway to public health coverage in Germany: challenges and opportunities based on first results.

    Lantzsch, Hendrikje / Eckhardt, Helene / Campione, Alessandro / Busse, Reinhard / Henschke, Cornelia

    BMC health services research

    2022  Volume 22, Issue 1, Page(s) 1182

    Abstract: Objectives: Evidence-based decision-making is the sine qua non for safe and effective patient care and the long-term functioning of health systems. Since 2020 Digital Health Applications (DiHA) in Germany have been undergoing a systematic pathway to be ... ...

    Abstract Objectives: Evidence-based decision-making is the sine qua non for safe and effective patient care and the long-term functioning of health systems. Since 2020 Digital Health Applications (DiHA) in Germany have been undergoing a systematic pathway to be reimbursed by statutory health insurance (SHI) which is attracting attention in other European countries. We therefore investigate coverage decisions on DiHA and the underlying evidence on health care effects, which legally include both medical outcomes and patient-centred structural and procedural outcomes.
    Methods: Based on publicly available data of the Institute for Medicines and Medical Devices searched between 08/2021 and 02/2022, all DiHA listed in the corresponding registry and thus reimbursable by the SHI were systematically investigated and presented descriptively on the basis of predefined criteria, such as clinical condition, and costs. The clinical trials on DiHA permanently included in the registry were reviewed with regard to their study design, endpoints investigated, the survey instruments used, and whether an intention-to-treat analysis was performed. Risk of bias was assessed using the ROB II tool.
    Results: By February 2022, 30 DiHA had been included in the DiHA registry, one third of them permanently and two thirds conditionally. Most DiHA were therapeutic applications for mental illness based on cognitive behavioural therapy. For all permanently included DiHA, randomised controlled trials were conducted to demonstrate the impact on health care effects. While medical outcomes were investigated for all of these DiHA, patient-centred structural and procedural outcomes were rarely investigated. The majority of clinical trials showed a high risk of bias, mainly due to insufficient reporting quality. Overall, the prices for DiHA covered by SHI are on average around € 150 per month (min. € 40; max. € 248).
    Conclusions: Evidence-based decision-making on coverage of DiHA leaves room for improvements both in terms of reporting-quality and the use of patient-centred structural and procedural outcomes in addition to medical outcomes. With appropriate evidence, DiHA can offer an opportunity as an adjunct to existing therapy while currently the high risk of bias of the trials raises doubts about the justification of its high costs.
    MeSH term(s) Cognitive Behavioral Therapy ; Germany ; Humans ; Mental Disorders ; National Health Programs ; Public Health
    Language English
    Publishing date 2022-09-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-022-08500-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cost-effectiveness of prehabilitation prior to elective surgery: a systematic review of economic evaluations.

    Rombey, Tanja / Eckhardt, Helene / Kiselev, Jörn / Silzle, Julia / Mathes, Tim / Quentin, Wilm

    BMC medicine

    2023  Volume 21, Issue 1, Page(s) 265

    Abstract: Background: Prehabilitation aims at enhancing patients' functional capacity and overall health status to enable them to withstand a forthcoming stressor like surgery. Our aim was to synthesise the evidence on the cost-effectiveness of prehabilitation ... ...

    Abstract Background: Prehabilitation aims at enhancing patients' functional capacity and overall health status to enable them to withstand a forthcoming stressor like surgery. Our aim was to synthesise the evidence on the cost-effectiveness of prehabilitation for patients awaiting elective surgery compared with usual preoperative care.
    Methods: We searched PubMed, Embase, the CRD database, ClinicalTrials.gov, the WHO ICTRP and the dissertation databases OADT and DART. Studies comparing prehabilitation for patients with elective surgery to usual preoperative care were included if they reported cost outcomes. All types of economic evaluations (EEs) were included. The primary outcome of the review was cost-effectiveness based on cost-utility analyses (CUAs). The risk of bias of trial-based EEs was assessed with the Cochrane risk of bias 2 tool and the ROBINS-I tool and the credibility of model-based EEs with the ISPOR checklist. Methodological quality of full EEs was assessed using the CHEC checklist. The EEs' results were synthesised narratively using vote counting based on direction of effect.
    Results: We included 45 unique studies: 25 completed EEs and 20 ongoing studies. Of the completed EEs, 22 were trial-based and three model-based, corresponding to four CUAs, three cost-effectiveness analyses, two cost-benefit analyses, 12 cost-consequence analyses and four cost-minimization analyses. Three of the four trial-based CUAs (75%) found prehabilitation cost-effective, i.e. more effective and/or less costly than usual care. Overall, 16/25 (64.0%) EEs found prehabilitation cost-effective. When excluding studies of insufficient credibility/critical risk of bias, this number reduced to 14/23 (60.9%). In 8/25 (32.0%), cost-effectiveness was unclear, e.g. because prehabilitation was more effective and more costly, and in one EE prehabilitation was not cost-effective.
    Conclusions: We found some evidence that prehabilitation for patients awaiting elective surgery is cost-effective compared to usual preoperative care. However, we suspect a relevant risk of publication bias, and most EEs were of high risk of bias and/or low methodological quality. Furthermore, there was relevant heterogeneity depending on the population, intervention and methods. Future EEs should be performed over a longer time horizon and apply a more comprehensive perspective.
    Trial registration: PROSPERO CRD42020182813.
    MeSH term(s) Cost-Effectiveness Analysis ; Preoperative Exercise ; Humans ; Elective Surgical Procedures
    Language English
    Publishing date 2023-07-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2131669-7
    ISSN 1741-7015 ; 1741-7015
    ISSN (online) 1741-7015
    ISSN 1741-7015
    DOI 10.1186/s12916-023-02977-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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