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Book ; Thesis: Effects of alpha-linolenic acid and quercetin on n-3 polyunsaturated fatty acid status and cardiovascular disease risk markers in metabolically healthy men and women

Burak, Constanze Felicitas / Egert, Sarah

2019

Institution	Rheinische Friedrich-Wilhelms-Universität Bonn
Author's details	von Constanze Felicitas Burak ; Referentin: PD Dr. Sarah Egert
Language	English
Size	VII, 187 Seiten, Diagramme
Edition	1. Auflage
Publisher	VVB Laufersweiler Verlag
Publishing place	Gießen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Dissertation, Rheinische Friedrich-Wilhelms-Universität Bonn, 2018
HBZ-ID	HT019961538
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2019 A 323	available for loan (reading room)	Lesesaal EG

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Book ; Thesis: Der Einfluss von omega-3-Polyensäuren auf Lipidstoffwechsel, Zusammensetzung und Oxidationsempfindlichkeit von Lipoproteinen geringer Dichte sowie endotheliale Adhäsionsmoleküle

Egert, Sarah

streng kontrollierte Ernährungsstudie bei gesunden Probanden

(Schriftenreihe des Instituts für Humanernährung und Lebensmittelkunde der Christian-Albrechts-Universität zu Kiel ; 35)

2006

Author's details	Sarah Egert
Series title	Schriftenreihe des Instituts für Humanernährung und Lebensmittelkunde der Christian-Albrechts-Universität zu Kiel ; 35
Collection
Keywords	Arteriosklerose ; Omega-3-Fettsäuren ; Rapsöl ; Projekt
Subject	Pilotprojekt ; Vorhaben ; Modellprojekt ; Projekte ; Polyenfettsäuren ; Fettsäuren ; Fischölfettsäuren ; N-3-Fettsäuren ; Arterienverkalkung ; Atherosklerose ; Arteriosclerosis
Language	German
Size	X, 180, 37 S., Ill., graph. Darst., 21 cm
Publisher	Der Andere Verl
Publishing place	Tönning u.a.
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Kiel, Univ., Diss., 2006
Note	Zsfassung in engl. Sprache
HBZ-ID	HT014886976
ISBN	3-89959-453-3 ; 978-3-89959-453-9
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
068/1439	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: A Systematic Review of the Impact of Fat Quantity and Fatty Acid Composition on Postprandial Vascular Function in Healthy Adults and Patients at Risk of Cardiovascular Disease.

Kienēs, Hannah F / Egert, Sarah

Current developments in nutrition

2023 Volume 7, Issue 12, Page(s) 102025

Abstract: Atherosclerosis is a key risk factor for developing cardiovascular diseases (CVDs). Flow-mediated dilation (FMD), which reflects vascular reactivity, as well as pulse wave velocity (PWV) and augmentation index (AIx), both markers of arterial stiffness, ... ...

Abstract	Atherosclerosis is a key risk factor for developing cardiovascular diseases (CVDs). Flow-mediated dilation (FMD), which reflects vascular reactivity, as well as pulse wave velocity (PWV) and augmentation index (AIx), both markers of arterial stiffness, have emerged as noninvasive, subclinical atherosclerotic markers for the early stages of altered vascular function. In addition to the long-term effects of diet, postprandial processes have been identified as important determinants of CVD risk, and evidence suggests an acute effect of fat quantity and fatty acid (FA) composition on vascular function. However, robust analyses of this association are lacking, especially concerning parameters of arterial stiffness. Therefore, we carried out a systematic literature search in PubMed, Scopus, and the Cochrane Library to investigate the impact of fat quantity and FA composition of meals on postprandial vascular function. Postprandial studies measuring FMD, PWV, and/or AIx in healthy adults and subjects with increased CVD risk (e.g., those with hypercholesterolemia or metabolic syndrome) were analyzed. In total, 24 articles were included; 9 studies focused on the effect of high-fat meals compared with control; and 15 studies investigated the effects of different fat sources. We found that consumption of a high-fat meal causes a reduction in FMD (decrease in vasodilation) and AIx (decrease in arterial stiffness). For eicosapentaenoic acid/docosahexaenoic acid (from fish oil), postprandial assessment (FMD and AIx) indicates a beneficial effect on vascular function. There is limited evidence of an influence of CVD risk on the vascular response to meals with varying fat doses or FA composition. However, meaningful conclusions were difficult to draw because of the large heterogeneity of the studies. Inconsistent results regarding both the impact of fat dose and FA composition on postprandial vascular function should be noted. We propose standardized methods for postprandial protocols to improve data quality in future studies. This review was registered in PROSPERO as CRD42022352986.
Language	English
Publishing date	2023-10-30
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2475-2991
ISSN (online)	2475-2991
DOI	10.1016/j.cdnut.2023.102025
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online ; Thesis: Aufbau einer deutschen Datenbank für bioaktive Pflanzenstoffe und Erweiterung des nutriRECIPE-Algorithmus um bioaktive Pflanzenstoffe sowie Bewertung von Mahlzeiten in der Gemeinschaftsverpflegung und Lebensmitteln im Lebensmitteleinzelhandel

Forner, Frank [Verfasser] / Stangl, Gabriele I. [Gutachter] / Egert, Sarah [Gutachter]

2024

Author's details	Frank Forner ; Gutachter: Gabriele I. Stangl, Sarah Egert
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	German
Publisher	Universitäts- und Landesbibliothek Sachsen-Anhalt
Publishing place	Halle (Saale)
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article ; Online: Impact of Meal Fatty Acid Composition on Postprandial Lipemia in Metabolically Healthy Adults and Individuals with Cardiovascular Disease Risk Factors: A Systematic Review.

Neumann, Hannah F / Egert, Sarah

Advances in nutrition (Bethesda, Md.)

2021 Volume 13, Issue 1, Page(s) 193–207

Abstract: Consuming fat results in postprandial lipemia, which is defined as an increase in blood triglyceride (TG) concentration. According to current knowledge, an excessively elevated postprandial TG concentration increases the risk of cardiovascular disease ( ... ...

Abstract	Consuming fat results in postprandial lipemia, which is defined as an increase in blood triglyceride (TG) concentration. According to current knowledge, an excessively elevated postprandial TG concentration increases the risk of cardiovascular disease (CVD). It is well known that meal-dependent (e.g., nutrient composition) as well as meal-independent factors (e.g., age) determine the magnitude of the lipemic response. However, there is conflicting evidence concerning the influence of fatty acid (FA) composition on postprandial TG concentration. The FA composition of a meal depends on the fat source used; for example, butter and coconut oil are rich in SFAs, while olive oil and canola oil have a high content of unsaturated FAs. To investigate the influence of meals prepared with fat sources rich in either SFAs or unsaturated FAs on postprandial lipemia, we carried out a systematic literature search in PubMed, Scopus, and the Cochrane Library. Randomized crossover studies were analyzed and the AUC of postprandial TG concentration served as the primary outcome measure. To examine the influence of health status, we differentiated between metabolically healthy individuals and those with CVD risk factors. In total, 23 studies were included. The results show that, in metabolically healthy adults, the FA composition of a meal is not a relevant determinant of postprandial lipemia. However, in individuals with CVD risk factors, SFA-rich meals (>32 g SFA/meal) often elicited a stronger lipemic response than meals rich in unsaturated FAs. The results suggest that adults with hypertriglyceridemia, an elevated BMI (≥30 kg/m2), and/or who are older (>40 y) may benefit from replacing SFA sources with unsaturated FAs. These hypotheses need to be verified by further studies in people with CVD risk factors using standardized postprandial protocols. This review was registered in PROSPERO as CRD42021214508 (https://www.crd.york.ac.uk/prospero/).
MeSH term(s)	Adult ; Cardiovascular Diseases/etiology ; Dietary Fats ; Fatty Acids ; Humans ; Hyperlipidemias/etiology ; Meals ; Postprandial Period/physiology ; Triglycerides
Chemical Substances	Dietary Fats ; Fatty Acids ; Triglycerides
Language	English
Publishing date	2021-08-24
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	2583634-1
ISSN	2156-5376 ; 2156-5376
ISSN (online)	2156-5376
ISSN	2156-5376
DOI	10.1093/advances/nmab096
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Concept of an Intervention for Sustainable Weight Loss in Postmenopausal Women with Overweight-Secondary Analysis of a Randomized Dietary Intervention Study.

Englert, Isabell / Egert, Sarah / Hoffmann, Laura / Kohlenberg-Müller, Kathrin

Nutrients

2023 Volume 15, Issue 14

Abstract: Introduction: The approach of an individual diet has great potential for sustainable weight reduction. Social support, participation and empowerment are also key factors for high motivation and compliance. So, the impact of an individual diet in ... ...

Abstract	Introduction: The approach of an individual diet has great potential for sustainable weight reduction. Social support, participation and empowerment are also key factors for high motivation and compliance. So, the impact of an individual diet in combination with group sessions on weight loss in postmenopausal women with overweight was investigated. Methods: In this reanalysis of a controlled intervention study, postmenopausal women ( Results: Forty-six women completed the intervention phase, and 29 completed the follow-up. Average weight loss was -5.8 ± 3.0 kg ( Conclusions: The individual nutrition approach with a focus on nutritype in combination with group sessions was effective for long-lasting weight loss in postmenopausal women. An important factor is close individual and group support.
MeSH term(s)	Aged ; Female ; Humans ; Middle Aged ; Diet ; Overweight/therapy ; Postmenopause ; Weight Loss
Language	English
Publishing date	2023-07-22
Publishing country	Switzerland
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15143250
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Review of Validated Methods to Evaluate Diet History in Diet Therapy and Counselling: An Overview and Analysis of Screeners Based on Food-Based Dietary Guidelines.

Hoffmann, Laura / Egert, Sarah / Allgaier, Joachim / Kohlenberg-Müller, Kathrin

Nutrients

2023 Volume 15, Issue 21

Abstract: Evidence-based dietetic practice calls for systematically developed assessment methods for nutritional assessment in dietetic counselling and therapy (DCT). Screeners can provide a quick and easy way to determine a client's diet quality and contribute to ...

Abstract	Evidence-based dietetic practice calls for systematically developed assessment methods for nutritional assessment in dietetic counselling and therapy (DCT). Screeners can provide a quick and easy way to determine a client's diet quality and contribute to quality assurance in DCT. The aim of this systematic review was to give a comparative overview of screeners based on national food-based dietary guidelines (FBDGs) and to derive recommendations for developing an FBDG-based screener for DCT. The literature search in PubMed (MEDLINE), embase and Web of Science was conducted between May and July 2022, and updated in March 2023, in accordance with the consensus-based standards for the selection of health measurement instruments (COSMIN). The analysis focused on characteristics of screener design and measurement properties for screener testing. In total, 13 studies on 11 screeners based on FBDGs were included; 7 screeners were targeted to DCT. The content and scoring of screeners were based on the corresponding national FBDGs. The validity and/or reliability of screeners were investigated in 11 studies; responsiveness was not tested for any screener and practicality was considered in all studies. Based on the screeners reviewed, a systematic rationale to develop, enhance and test screeners based on national FBDGs was established.
MeSH term(s)	Humans ; Diet ; Dietetics ; Food ; Nutrition Policy ; Reproducibility of Results ; Guidelines as Topic
Language	English
Publishing date	2023-11-02
Publishing country	Switzerland
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15214654
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Potential Protective Protein Components of Cow’s Milk against Certain Tumor Entities

Leischner, Christian / Egert, Sarah / Burkard, Markus / Venturelli, Sascha

Nutrients. 2021 June 08, v. 13, no. 6

2021

Abstract: Milk and dairy products, especially from cow’s milk, play a major role in the daily human diet. It is therefore hardly surprising that the subject of milk is being extensively researched and that many effects of individual milk components have been ... ...

Abstract	Milk and dairy products, especially from cow’s milk, play a major role in the daily human diet. It is therefore hardly surprising that the subject of milk is being extensively researched and that many effects of individual milk components have been characterized as a result. With the wealth of results available today, the influence of milk on the development of various types of cancer and, in particular, its often protective effects have been shown both in vitro and in vivo and in the evaluation of large-scale cohort and case-control studies. Various caseins, diverse whey proteins such as α-lactalbumin (α-LA), bovine α-lactalbumin made lethal to tumor cells (BAMLET), β-lactoglobulin (β-LG), or bovine serum albumin (BSA), and numerous milk fat components, such as conjugated linoleic acid (CLA), milk fat globule membrane (MFGM), or butyrate, as well as calcium and other protein components such as lactoferrin (Lf), lactoferricin (Lfcin), and casomorphines, show antitumor or cytotoxic effects on cells from different tumor entities. With regard to a balanced and health-promoting diet, milk consumption plays a major role in a global context. This work provides an overview of what is known about the antitumoral properties of proteins derived from cow’s milk and their modes of action.
Keywords	bovine serum albumin ; butyrates ; calcium ; conjugated linoleic acid ; cows ; cytotoxicity ; health promotion ; human nutrition ; lactoferrin ; milk ; milk consumption ; milk fat ; neoplasms ; whey
Language	English
Dates of publication	2021-0608
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13061974
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Bioavailability and Cardiometabolic Effects of Xanthohumol: Evidence from Animal and Human Studies.

Neumann, Hannah F / Frank, Jan / Venturelli, Sascha / Egert, Sarah

Molecular nutrition & food research

2022 Volume 66, Issue 6, Page(s) e2100831

Abstract: Xanthohumol is the main prenylflavonoid in hops and has been associated with a wide range of health benefits, due to its anti-inflammatory, anti-oxidative, and cancer-preventive properties. Increasing evidence suggests that xanthohumol positively affects ...

Abstract	Xanthohumol is the main prenylflavonoid in hops and has been associated with a wide range of health benefits, due to its anti-inflammatory, anti-oxidative, and cancer-preventive properties. Increasing evidence suggests that xanthohumol positively affects biomarkers associated with metabolic syndrome and cardiovascular diseases (CVDs). This review summarizes the effects of xanthohumol supplementation on body weight, lipid and glucose metabolism, systemic inflammation, and redox status. In addition, it provides insights into the pharmacokinetics of xanthohumol intake. Animal studies show that xanthohumol exerts beneficial effects on body weight, lipid profile, glucose metabolism, and other biochemical parameters associated with metabolic syndrome and CVDs. Although in vitro studies are increasingly elucidating the responsible mechanisms, the overall in vivo results are currently inconsistent and quantitatively insufficient. Pharmacokinetic and safety studies confirm that intake of xanthohumol is safe and well tolerated in both animals and humans. However, little is known about the metabolism of xanthohumol in the human body, and even less about its effects on body weight and CVD risk factors. There is an urgent need for studies investigating whether the effects of xanthohumol on body weight and cardiometabolic parameters observe in animal studies are reproducible in humans, and what dosage, formulation, and intervention period are required.
MeSH term(s)	Animals ; Biological Availability ; Body Weight ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Flavonoids/adverse effects ; Glucose ; Humans ; Lipids ; Metabolic Syndrome/chemically induced ; Propiophenones/adverse effects
Chemical Substances	Flavonoids ; Lipids ; Propiophenones ; Glucose (IY9XDZ35W2) ; xanthohumol (T4467YT1NT)
Language	English
Publishing date	2022-01-14
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2160372-8
ISSN	1613-4133 ; 1613-4125
ISSN (online)	1613-4133
ISSN	1613-4125
DOI	10.1002/mnfr.202100831
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Potential Protective Protein Components of Cow's Milk against Certain Tumor Entities.

Leischner, Christian / Egert, Sarah / Burkard, Markus / Venturelli, Sascha

Nutrients

2021 Volume 13, Issue 6

Abstract: Milk and dairy products, especially from cow's milk, play a major role in the daily human diet. It is therefore hardly surprising that the subject of milk is being extensively researched and that many effects of individual milk components have been ... ...

Abstract	Milk and dairy products, especially from cow's milk, play a major role in the daily human diet. It is therefore hardly surprising that the subject of milk is being extensively researched and that many effects of individual milk components have been characterized as a result. With the wealth of results available today, the influence of milk on the development of various types of cancer and, in particular, its often protective effects have been shown both in vitro and in vivo and in the evaluation of large-scale cohort and case-control studies. Various caseins, diverse whey proteins such as α-lactalbumin (α-LA), bovine α-lactalbumin made lethal to tumor cells (BAMLET), β-lactoglobulin (β-LG), or bovine serum albumin (BSA), and numerous milk fat components, such as conjugated linoleic acid (CLA), milk fat globule membrane (MFGM), or butyrate, as well as calcium and other protein components such as lactoferrin (Lf), lactoferricin (Lfcin), and casomorphines, show antitumor or cytotoxic effects on cells from different tumor entities. With regard to a balanced and health-promoting diet, milk consumption plays a major role in a global context. This work provides an overview of what is known about the antitumoral properties of proteins derived from cow's milk and their modes of action.
MeSH term(s)	Animals ; Cattle ; Chemoprevention ; Milk/chemistry ; Milk Proteins/therapeutic use ; Neoplasms/drug therapy ; Neoplasms/prevention & control ; Peptides/therapeutic use
Chemical Substances	Milk Proteins ; Peptides
Language	English
Publishing date	2021-06-08
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu13061974
Database	MEDical Literature Analysis and Retrieval System OnLINE

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