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  1. Article ; Online: Perinatal outcomes.

    Ehrhardt, Peter

    Archives of disease in childhood. Fetal and neonatal edition

    2014  Volume 99, Issue 6, Page(s) F521

    MeSH term(s) Female ; Fetal Death/epidemiology ; Humans ; Infant Mortality ; Infant, Extremely Premature ; Infant, Premature, Diseases/mortality ; Intensive Care Units, Neonatal/statistics & numerical data ; Male ; Patient Transfer/statistics & numerical data ; Perinatal Mortality
    Language English
    Publishing date 2014-09-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2007331-8
    ISSN 1468-2052 ; 1359-2998
    ISSN (online) 1468-2052
    ISSN 1359-2998
    DOI 10.1136/archdischild-2014-307338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Extrakorporale Stosswellentherapie bei Tendopathie der Achillessehne

    Ehrhardt, Peter

    2009  

    Author's details vorgelegt von Peter Ehrhardt
    Size 83 Blatt
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Universität, Dissertation, 2009
    HBZ-ID HT016344206
    Database Central Library of Sport Science of the German Sport University Cologne

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  3. Article: Original Paper. Effekte plyometrischen Trainings unter Verwendung instabiler Untergründe auf sportmotorische Sprung- und Schnelligkeitsleistungen von Nachwuchsleistungshandballern

    Büsch, Dirk / Pabst, Jan / Mühlbauer, Thomas / Ehrhardt, Peter / Granacher, Urs

    Sports orthopaedics and traumatology

    2015  Volume 31, Issue 4, Page(s) 299

    Language German
    Document type Article
    ZDB-ID 1233784-5
    ISSN 0177-0438 ; 0949-328X
    Database Current Contents Medicine

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  4. Article: Detection of MAGE-A transcripts in bone marrow is an independent prognostic factor in operable non-small-cell lung cancer.

    Sienel, Wulf / Mecklenburg, Ingo / Dango, Sebastian / Ehrhardt, Peter / Kirschbaum, Andreas / Passlick, Bernward / Pantel, Klaus

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2007  Volume 13, Issue 13, Page(s) 3840–3847

    Abstract: Purpose: MAGE-A gene expression in humans is mostly restricted to tumor cells, and the role of MAGE-A transcripts and peptides as diagnostic markers and therapeutic targets is currently under investigation. Thus far, the clinical relevance of MAGE-A ... ...

    Abstract Purpose: MAGE-A gene expression in humans is mostly restricted to tumor cells, and the role of MAGE-A transcripts and peptides as diagnostic markers and therapeutic targets is currently under investigation. Thus far, the clinical relevance of MAGE-A transcripts as marker for disseminated tumor cells in bone marrow of patients with operable lung cancer without overt metastases is still unclear.
    Experimental design: Preoperative bone marrow aspirates from 50 consecutive patients with operable non-small-cell lung cancer free of distant metastases (i.e., pT(1-4) pN(0-2) M(0) R(0)) were admitted to the study. Each bone marrow sample was divided and examined using multimarker MAGE-A reverse transcription-PCR (RT-PCR) and immunocytochemical staining with the anti-pancytokeratin antibody A45-B/B3. Multimarker MAGE-A RT-PCR consisted of multiple subtype-specific nested RT-PCRs with primers for MAGE-A1, MAGE-A2, MAGE-A3/6, MAGE-A4, and MAGE-A12. The median follow-up duration was 92 months (range, 18-110 months).
    Results: Twenty-six (52%) lung cancer patients harbored MAGE-A transcripts in their bone marrow, as opposed to none of the 30 healthy controls tested. In all 7 patients with immunocytochemically positive bone marrow, MAGE-A transcripts were also detected. All different MAGE-A subtypes (MAGE-A1, MAGE-A2, MAGE-A3/6, MAGE-A4, and MAGE-A12) were observed. Sixty-five percent of patients with MAGE-A transcripts in bone marrow exhibited only one subtype. Univariate (P = 0.03, log-rank-test) and multivariate survival analysis showed that MAGE-A transcripts in bone marrow were associated with poor outcome in pN(0) patients (P = 0.02; relative risk, 7.6).
    Conclusions: Detection of MAGE-A transcripts in bone marrow predicts an unfavorable outcome in patients with early-stage operable lung cancer. This finding indicates that MAGE-A transcripts are clinically relevant markers of micrometastatic spread in lung cancer and supports further investigation of MAGE-A as potential future therapeutic target.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antigens, Neoplasm ; Bone Marrow Cells/metabolism ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Male ; Melanoma-Specific Antigens ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Proteins/biosynthesis ; Neoplasm Proteins/genetics ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction
    Chemical Substances Antigens, Neoplasm ; Melanoma-Specific Antigens ; Neoplasm Proteins
    Language English
    Publishing date 2007-07-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-06-2507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The future in diagnosis and staging of lung cancer. Molecular techniques.

    Sienel, Wulf / Dango, Sebastian / Ehrhardt, Peter / Eggeling, Stephan / Kirschbaum, Andreas / Passlick, Bernward

    Respiration; international review of thoracic diseases

    2006  Volume 73, Issue 5, Page(s) 575–580

    Abstract: Lung cancers at the same stage of disease have markedly different rates of disease progression. In this review, we will address current molecular techniques which provide new opportunities according to diagnosis, prediction of survival or selection of ... ...

    Abstract Lung cancers at the same stage of disease have markedly different rates of disease progression. In this review, we will address current molecular techniques which provide new opportunities according to diagnosis, prediction of survival or selection of therapy. New molecular techniques might be helpful in TNM staging and lead to additional individual prognostic information. A revised TNM system could include a TNM component and a molecular supplemental component allowing new markers to be evaluated without undermining the value of classic TNM staging. Furthermore, molecular techniques might be helpful in the early or differential diagnosis of lung cancer. Since many new targeted agents are effective only if their respective molecular markers are mutated or expressed at sufficient levels, DNA-based or RNA-based techniques have the potential to influence treatment selection in the future. Overall, we can expect that molecular markers will contribute to a more personalized lung cancer treatment.
    MeSH term(s) Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Molecular Diagnostic Techniques ; Neoplasm Staging
    Language English
    Publishing date 2006
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000095310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Conference proceedings: Lokale Radikalität bei Laser-Metastasektomien

    Sienel, Wulf / Ehrhardt, Peter / Dango, Sebastian / Kirschbaum, Andreas / Stremmel, Christian / Passlick, Bernward

    2010  , Page(s) 07dgtF2

    Event/congress 16. Jahrestagung der Deutschen Gesellschaft für Thoraxchirurgie; Konstanz; Deutsche Gesellschaft für Thoraxchirurgie; 2007
    Keywords Medizin, Gesundheit
    Publishing date 2010-03-22
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/07dgt24
    Database German Medical Science

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  7. Book ; Online: Extended Range Telepresence for Evacuation Training in Pedestrian Simulations

    Arias, Antonia Perez / Hanebeck, Uwe D. / Ehrhardt, Peter / Hengst, Stefan / Kretz, Tobias / Vortisch, Peter

    2010  

    Abstract: In this contribution, we propose a new framework to evaluate pedestrian simula-tions by using Extended Range Telepresence. Telepresence is used as a virtual reality walking simulator, which provides the user with a realistic impression of being present ... ...

    Abstract In this contribution, we propose a new framework to evaluate pedestrian simula-tions by using Extended Range Telepresence. Telepresence is used as a virtual reality walking simulator, which provides the user with a realistic impression of being present and walking in a virtual environment that is much larger than the real physical environment, in which the user actually walks. The validation of the simulation is performed by comparing motion data of the telepresent user with simulated data at some points of the simulation. The use of haptic feedback from the simulation makes the framework suitable for training in emergency situations.

    Comment: Contribution to Pedestrian and Evacuation Dynamics 2010 (PED2010) conference
    Keywords Computer Science - Human-Computer Interaction ; Computer Science - Multiagent Systems
    Publishing date 2010-02-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: The Future in Diagnosis and Staging of Lung Cancer

    Sienel, Wulf / Dango, Sebastian / Ehrhardt, Peter / Eggeling, Stephan / Kirschbaum, Andreas / Passlick, Bernward

    Respiration

    2006  Volume 73, Issue 5, Page(s) 575–580

    Abstract: Lung cancers at the same stage of disease have markedly different rates of disease progression. In this review, we will address current molecular techniques which provide new opportunities according to diagnosis, prediction of survival or selection of ... ...

    Institution Department of Thoracic Surgery, Albert-Ludwigs University Freiburg, Freiburg, Germany
    Abstract Lung cancers at the same stage of disease have markedly different rates of disease progression. In this review, we will address current molecular techniques which provide new opportunities according to diagnosis, prediction of survival or selection of therapy. New molecular techniques might be helpful in TNM staging and lead to additional individual prognostic information. A revised TNM system could include a TNM component and a molecular supplemental component allowing new markers to be evaluated without undermining the value of classic TNM staging. Furthermore, molecular techniques might be helpful in the early or differential diagnosis of lung cancer. Since many new targeted agents are effective only if their respective molecular markers are mutated or expressed at sufficient levels, DNA-based or RNA-based techniques have the potential to influence treatment selection in the future. Overall, we can expect that molecular markers will contribute to a more personalized lung cancer treatment.
    Keywords Neoplasm staging ; Proteomics ; Lung cancer ; Classification ; Diagnosis ; Genomics
    Language English
    Publishing date 2006-09-29
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Thematic Review Series 2006
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000095310
    Database Karger publisher's database

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  9. Book: Weiterbildungsberatung für Erwerbslose

    Braun, Joachim / Ehrhardt, Peter

    Aufbau und Erprobung von zehn kommunalen Beratungsstellen für Weiterbildung

    1981  

    Institution Deutsches Institut für Urbanistik
    Author's details Joachim Braun; Peter Ehrhardt
    Language German
    Size 321 S, graph. Darst
    Publisher Deutsches Institut für Urbanistik
    Publishing place Berlin
    Document type Book
    Note Literaturverz. S. 315 - 320
    ISBN 3881180621 ; 9783881180627
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Book ; Thesis: Untersuchungen über Bau und Funktion des Verdauungstraktes sowie zur Stoffwechselphysiologie von Megoura Viciae Buckt

    Ehrhardt, Peter

    Zeitschrift für vergleichende Physiologie ; 1962,46 (1. Teil) , Zeitschrift für Morphologie und Ökologie der Tiere ; 1963,52 (2. Teil)

    (Alphidae, Homoptera) unter besonderer Berücksichtigung der Nahrungsaufnahme und der Honigtauabgabe

    1962  

    Author's details Peter Ehrhardt
    Language German
    Size S. 169 - 211, S. 597 - 677
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Würzburg, 1963
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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